All Stories

  1. PLGA-PEI nanoparticle covered with poly(I:C) for personalised cancer immunotherapy

    Article • Drug Delivery and Translational Research, March 2024, Springer Science + Business Media

    Dr Ruben Varela-Calvino

  2. Self-assembled peptide/polymer hybrid nanoplatform for cancer immunostimulating therapies

    Article • Drug Delivery and Translational Research, September 2023, Springer Science + Business Media

    Dr Ruben Varela-Calvino

  3. Semisynthetic Pneumococcal Glycoconjugate Nanovaccine

    Article • Bioconjugate Chemistry, September 2023, American Chemical Society (ACS)

    Dr Ruben Varela-Calvino

  4. A ready-to-use dry powder formulation based on protamine nanocarriers for pulmonary drug delivery

    Article • European Journal of Pharmaceutical Sciences, June 2023, Elsevier

    Dr Ruben Varela-Calvino

  5. Development of rifabutin-loaded protamine nanocarriers for pulmonary drug delivery with improved aerodynamic properties

    Article • January 2023, University of Szeged

    Dr Ruben Varela-Calvino

  6. Dry Powder Comprised of Isoniazid-Loaded Nanoparticles of Hyaluronic Acid in Conjugation with Mannose-Anchored Chitosan for Macrophage-Targeted Pulmonary Administration in Tuberculosis

    Article • Pharmaceutics, July 2022, MDPI AG

    Dr Ruben Varela-Calvino

  7. Study of Plasma Anti-CD26 Autoantibody Levels in a Cohort of Treatment-Naïve Early Arthritis Patients

    Article • Archivum Immunologiae et Therapiae Experimentalis, March 2022, De Gruyter

    Dr Ruben Varela-Calvino

  8. Distinctive CD26 Expression on CD4 T-Cell Subsets

    Article • Biomolecules, October 2021, MDPI AG

    Dr Ruben Varela-Calvino

  9. The mechanism of sitagliptin inhibition of colorectal cancer cell lines' metastatic functionalities

    Article • IUBMB Life, March 2021, Wiley

    Dr Ruben Varela-Calvino

  10. A chitosan-based nanosystem as pneumococcal vaccine delivery platform

    Article • Drug Delivery and Translational Research, March 2021, Springer Science + Business Media

    Dr Ruben Varela-Calvino

  11. Bioinspired pollen microcapsules to overcome mucosal barriers

    Article • January 2021, University of Szeged

    Dr Ruben Varela-Calvino

  12. CD26-Related Serum Biomarkers: sCD26 Protein, DPP4 Activity, and Anti-CD26 Isotype Levels in a Colorectal Cancer-Screening Context

    Article • Disease Markers, January 2020, Wiley

    Dr Ruben Varela-Calvino

  13. Design of polymeric nanocapsules to improve their lympho-targeting capacity

    Article • Nanomedicine, December 2019, Future Medicine

    Dr Ruben Varela-Calvino

  14. Naturally presented HLA class I–restricted epitopes from the neurotrophic factor S100-β are targets of the autoimmune response in type 1 diabetes

    Article • The FASEB Journal, May 2019, Federation of American Societies For Experimental Biology (FASEB)

    Dr Ruben Varela-Calvino, Miguel Rodriguez, aurelio martis-sueiro, Cristina Calviño Sampedro

  15. IC-Tagging methodology applied to the expression of viral glycoproteins and the difficult-to-express membrane-bound IGRP autoantigen

    Article • Scientific Reports, November 2018, Springer Science + Business Media

    Dr Ruben Varela-Calvino

  16. Oral hygiene might prevent cancer

    Article • Heliyon, October 2018, Elsevier

    Dr Ruben Varela-Calvino

  17. BMPR2 gene is overexpressed in lymphoblastoid cell lines from Graves Disease patients

    Article • Journal of Cellular and Molecular Medicine, December 2017, Wiley

    Mr Mauro Lago Docampo, Dr Ruben Varela-Calvino, Sonia Prado López

  18. Anti-CD26 autoantibodies are involved in rheumatoid arthritis and show potential clinical interest

    Article • Clinical Biochemistry, November 2017, Elsevier

    Dr Ruben Varela-Calvino

  19. Apportioning Blame: Autoreactive CD4+ and CD8+ T Cells in Type 1 Diabetes

    Article • Archivum Immunologiae et Therapiae Experimentalis, January 2017, Springer Science + Business Media

    Dr Ruben Varela-Calvino

  20. Human peripheral blood mononuclear cell in vitro system to test the efficacy of food bioactive compounds: Effects of polyunsaturated fatty acids and their relation with BMI

    Article • Molecular Nutrition & Food Research, December 2016, Wiley

    Dr Ruben Varela-Calvino

  21. Correction: CD26 Expression on T Helper Populations and sCD26 Serum Levels in Patients with Rheumatoid Arthritis

    Article • PLOS One, September 2015, PLOS

    Dr Ruben Varela-Calvino

  22. Serum dipeptidyl peptidase IV activity and sCD26 concentration in patients with choroidal nevus or uveal melanoma

    Article • Clinica Chimica Acta, August 2015, Elsevier

    Dr Ruben Varela-Calvino

  23. CD26 Expression on T Helper Populations and sCD26 Serum Levels in Patients with Rheumatoid Arthritis

    Article • PLOS One, July 2015, PLOS

    Dr Ruben Varela-Calvino

  24. Characterization of the autoimmune response against the nerve tissue S100β in patients with type 1 diabetes

    Article • Clinical & Experimental Immunology, April 2015, Wiley

    Dr Ruben Varela-Calvino

  25. Immunology and Immunotherapy of Colorectal Cancer

    Article • January 2015, Springer Science + Business Media

    Dr Ruben Varela-Calvino

  26. Stem and immune cells in colorectal primary tumour: Number and function of subsets may diagnose metastasis

    Article • World Journal of Immunology, January 2015, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Dr Ruben Varela-Calvino

  27. Galectin-1 synthesis in type 1 diabetes by different immune cell types: Reduced synthesis by monocytes and Th1 cells

    Article • Cellular Immunology, January 2011, Elsevier

    Dr Ruben Varela-Calvino

  28. Autoantibodies to glial fibrillary acid protein and S100β in diabetic patients

    Article • Diabetic Medicine, February 2010, Wiley

    Dr Ruben Varela-Calvino

  29. CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

    Article • Journal of Clinical Investigation, September 2009, American Society for Clinical Investigation

    Dr Ruben Varela-Calvino

  30. CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

    Article • Journal of Clinical Investigation, September 2009, American Society for Clinical Investigation

    Dr Ruben Varela-Calvino

  31. CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

    Article • Journal of Clinical Investigation, September 2008, American Society for Clinical Investigation

    Dr Ruben Varela-Calvino

  32. Role of the capsid protein VP4 in the plasma-dependent enhancement of the Coxsackievirus B4E2-infection of human peripheral blood cells

    Article • Virus Research, May 2007, Elsevier

    Dr Ruben Varela-Calvino

  33. Tissue-polypeptide-specific antigen levels in diabetic patients with normal and pathological biochemical profiles

    Article • Clinical Biochemistry, February 2007, Elsevier

    Dr Ruben Varela-Calvino

  34. HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides

    Article • Immunology, November 2005, Wiley

    Dr Ruben Varela-Calvino

  35. Identification of a Naturally Processed Cytotoxic CD8 T-Cell Epitope of Coxsackievirus B4, Presented by HLA-A2.1 and Located in the PEVKEK Region of the P2C Nonstructural Protein

    Article • Journal of Virology, December 2004, ASM Journals

    Dr Ruben Varela-Calvino

  36. Cellular Immune Activation in Gulf War Veterans

    Article • Journal of Clinical Immunology, January 2004, Springer Science + Business Media

    Dr Ruben Varela-Calvino, Matthew Hotopf

  37. Enteroviruses and type 1 diabetes

    Article • Diabetes/Metabolism Research and Reviews, January 2003, Wiley

    Dr Ruben Varela-Calvino

  38. Characterization of the T-Cell Response to Coxsackievirus B4: Evidence That Effector Memory Cells Predominate in Patients With Type 1 Diabetes

    Article • Diabetes, June 2002, American Diabetes Association

    Dr Ruben Varela-Calvino

  39. 3β Hydroxysteroid Dehydrogenase Autoantibodies in Patients with Idiopathic Premature Ovarian Failure Target N- and C-Terminal Epitopes

    Article • The Journal of Clinical Endocrinology & Metabolism, December 2001, Endocrine Society

    Dr Ruben Varela-Calvino

  40. 3  Hydroxysteroid Dehydrogenase Autoantibodies in Patients with Idiopathic Premature Ovarian Failure Target N- and C-Terminal Epitopes

    Article • The Journal of Clinical Endocrinology & Metabolism, December 2001, Endocrine Society

    Dr Ruben Varela-Calvino

  41. T Cell Activation by Coxsackievirus B4 Antigens in Type 1 Diabetes Mellitus: Evidence for Selective TCR V  Usage Without Superantigenic Activity

    Article • The Journal of Immunology, September 2001, The American Association of Immunologists

    Dr Ruben Varela-Calvino

  42. T-Cell Reactivity to the P2C Nonstructural Protein of a Diabetogenic Strain of Coxsackievirus B4

    Article • Virology, August 2000, Elsevier

    Dr Ruben Varela-Calvino

  43. Endogenous Enzymatic Activities of the Avian Reovirus S1133: Identification of the Viral Capping Enzyme

    Article • Virology, February 1995, Elsevier

    Dr Ruben Varela-Calvino