All Stories

  1. DNA methylation profiles in cancer: functions, therapy, and beyond
  2. Oncogenic Role of HMGB1 as An Alarming in Robust Prediction of Immunotherapy Response in Colorectal Cancer
  3. MYBL1 induces transcriptional activation of ANGPT2 to promote tumor angiogenesis and confer sorafenib resistance in human hepatocellular carcinoma
  4. Cordycepin enhances anti-tumor immunity in colon cancer by inhibiting phagocytosis immune checkpoint CD47 expression
  5. Parthenolide Suppresses T Helper 17 and Alleviates Experimental Autoimmune Encephalomyelitis
  6. Cell pyroptosis in health and inflammatory diseases
  7. Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/Neutrophil Elastase Signaling in Mice
  8. Targeting TRIM54/Axin1/β-Catenin Axis Prohibits Proliferation and Metastasis in Hepatocellular Carcinoma
  9. MMP12 knockout prevents weight and muscle loss in tumor-bearing mice
  10. Erratum to Thermosensitive injectable hydrogel enhances the antitumor effect of embelin in mouse hepatocellular carcinoma [Journal of Pharmaceutical Sciences 103 (2014) 965–973]
  11. miR-194-5p down-regulates tumor cell PD-L1 expression and promotes anti-tumor immunity in pancreatic cancer
  12. Arctigenin Exerts Neuroprotective Effect by Ameliorating Cortical Activities in Experimental Autoimmune Encephalomyelitis In Vivo
  13. Loss of fragile site-associated tumor suppressor promotes antitumor immunity via macrophage polarization
  14. Andrographolide Suppresses the Growth and Metastasis of Luminal-Like Breast Cancer by Inhibiting the NF-κB/miR-21-5p/PDCD4 Signaling Pathway
  15. Microglial PGC-1α protects against ischemic brain injury by suppressing neuroinflammation
  16. MMP12 Knockout Prevent Weight and Muscle Loss Induced by Cancer Cachexia
  17. Upregulation of TNF-α and IL-6 induces preterm premature rupture of membranes by activation of ADAMTS-9 in embryonic membrane cells
  18. Effect of AKT1 (p. E17K) Hotspot Mutation on Malignant Tumorigenesis and Prognosis
  19. Arctigenin protects mice from thioglycollate‐induced acute peritonitis
  20. A Bromodomain-Containing Protein 4 (BRD4) Inhibitor Suppresses Angiogenesis by Regulating AP-1 Expression
  21. Restoration of miR-340 controls pancreatic cancer cell CD47 expression to promote macrophage phagocytosis and enhance antitumor immunity
  22. miR-128 Regulates Tumor Cell CD47 Expression and Promotes Anti-tumor Immunity in Pancreatic Cancer
  23. Use of copper-cysteamine nanoparticles to simultaneously enable radiotherapy, oxidative therapy and immunotherapy for melanoma treatment
  24. Apolipoprotein A-I Mimetic Peptide L-4F Suppresses Granulocytic-Myeloid-Derived Suppressor Cells in Mouse Pancreatic Cancer
  25. miR-21 promotes NLRP3 inflammasome activation to mediate pyroptosis and endotoxic shock
  26. Parthenolide regulates oxidative stress‐induced mitophagy and suppresses apoptosis through p53 signaling pathway in C2C12 myoblasts
  27. Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1
  28. Embelin impairs the accumulation and activation of MDSCs in colitis-associated tumorigenesis
  29. Arctigenin protects against liver injury from acute hepatitis by suppressing immune cells in mice
  30. MicroRNA-181c promotes Th17 cell differentiation and mediates experimental autoimmune encephalomyelitis
  31. lincRNA-Cox2 regulates NLRP3 inflammasome and autophagy mediated neuroinflammation
  32. PD-1/PD-L1 pathway blockade works as an effective and practical therapy for cancer immunotherapy
  33. Apolipoprotein A-I mimetic peptide 4F suppresses tumor-associated macrophages and pancreatic cancer progression
  34. Activation of Adiponectin Receptor Regulates Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Inhibits Lesions in ApoE-Deficient Mice
  35. Overexpression of CHD1L is associated with poor survival and aggressive tumor biology in esophageal carcinoma
  36. tRF/miR-1280 Suppresses Stem Cell–like Cells and Metastasis in Colorectal Cancer
  37. Adiponectin modulates oxidative stress-induced mitophagy and protects C2C12 myoblasts against apoptosis
  38. miR-142-5p regulates tumor cell PD-L1 expression and enhances anti-tumor immunity
  39. Interferon regulatory factor-1 activates autophagy to aggravate hepatic ischemia-reperfusion injury via the P38/P62 pathway in mice
  40. CAR-T cell therapy in gastrointestinal tumors and hepatic carcinoma: From bench to bedside
  41. Plumbagin protects liver against fulminant hepatic failure and chronic liver fibrosis via inhibiting inflammation and collagen production
  42. Parthenolide ameliorates Concanavalin A-induced acute hepatitis in mice and modulates the macrophages to an anti-inflammatory state
  43. Vitexin suppresses autophagy to induce apoptosis in hepatocellular carcinoma via activation of the JNK signaling pathway
  44. Adiponectin Suppresses T Helper 17 Cell Differentiation and Limits Autoimmune CNS Inflammation via the SIRT1/PPARγ/RORγt Pathway
  45. mTORC1 pathway disruption ameliorates brain inflammation following stroke via a shift in microglia phenotype from M1 type to M2 type
  46. LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway
  47. Correction: Corrigendum: Adiponectin-derived active peptide ADP355 exerts anti-inflammatory and anti-fibrotic activities in thioacetamide-induced liver injury
  48. Bi-directional roles of IRF-1 on autophagy diminish its prognostic value as compared with Ki67 in liver transplantation for hepatocellular carcinoma
  49. Differentially expressed lncRNAs and mRNAs identified by microarray analysis in GBS patients vs healthy controls
  50. Mesenchymal stem cells and their secreted molecules predominantly ameliorate fulminant hepatic failure and chronic liver fibrosis in mice respectively
  51. Expression Profile of Long Noncoding RNA s in Peripheral Blood Mononuclear Cells from Multiple Sclerosis Patients
  52. Macrophage targeting contributes to the inhibitory effects of embelin on colitis-associated cancer
  53. Adiponectin-derived active peptide ADP355 exerts anti-inflammatory and anti-fibrotic activities in thioacetamide-induced liver injury
  54. Chrysin suppresses human CD14+ monocyte-derived dendritic cells and ameliorates experimental autoimmune encephalomyelitis
  55. Arctigenin Suppress Th17 Cells and Ameliorates Experimental Autoimmune Encephalomyelitis Through AMPK and PPAR-γ/ROR-γt Signaling
  56. Epigenetics in autoimmune diseases: Pathogenesis and prospects for therapy
  57. T cell immunity to glatiramer acetate ameliorates cognitive deficits induced by chronic cerebral hypoperfusion by modulating the microenvironment
  58. Impact of Immune Response on the Use of iPSCs in Disease Modeling
  59. Structural Mediation on Polycation Nanoparticles by Sulfadiazine to Enhance DNA Transfection Efficiency and Reduce Toxicity
  60. Chrysin Protects against Focal Cerebral Ischemia/Reperfusion Injury in Mice through Attenuation of Oxidative Stress and Inflammation
  61. Embelin inhibits pancreatic cancer progression by directly inducing cancer cell apoptosis and indirectly restricting IL-6 associated inflammatory and immune suppressive cells11These authors contributed equally to this work.
  62. Plumbagin suppresses dendritic cell functions and alleviates experimental autoimmune encephalomyelitis
  63. ZSTK474, a novel PI3K inhibitor, modulates human CD14+ monocyte-derived dendritic cell functions and suppresses experimental autoimmune encephalomyelitis
  64. Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1α signaling
  65. Embelin Reduces Colitis-Associated Tumorigenesis through Limiting IL-6/STAT3 Signaling
  66. Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer
  67. Thermosensitive Injectable Hydrogel Enhances the Antitumor Effect of Embelin in Mouse Hepatocellular Carcinoma
  68. Chrysin attenuates experimental autoimmune neuritis by suppressing immuno-inflammatory responses
  69. Regulatory non-coding RNAs: revolutionizing the RNA world
  70. Epigenetics: The Language of the Cell?
  71. Embelin Suppresses Dendritic Cell Functions and Limits Autoimmune Encephalomyelitis Through the TGF-β/β-catenin and STAT3 Signaling Pathways
  72. Immune microenvironment profiles of tumor immune equilibrium and immune escape states of mouse sarcoma
  73. Vorinostat, a histone deacetylase inhibitor, suppresses dendritic cell function and ameliorates experimental autoimmune encephalomyelitis
  74. Obesity-related hepatocellular carcinoma: roles of risk factors altered in obesity
  75. XIAP-associated factor 1 (XAF1), a novel target of p53, enhances p53-mediated apoptosis via post-translational modification
  76. Incorporation of CD40 ligand into SHIV virus-like particles (VLP) enhances SHIV-VLP-induced dendritic cell activation and boosts immune responses against HIV
  77. C-Reactive Protein Promotes Cardiac Fibrosis and Inflammation in Angiotensin II–Induced Hypertensive Cardiac Disease
  78. Adenovirus-mediated down-regulation of X-linked inhibitor of apoptosis protein inhibits colon cancer
  79. Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer
  80. IL-6 stimulates Th2 type cytokine secretion and upregulates VEGF and NRP-1 expression in pancreatic cancer cells
  81. Elevated Interleukin-6 and G-CSF in Human Pancreatic Cancer Cell Conditioned Medium Suppress Dendritic Cell Differentiation and Activation
  82. Thymosin-α1 modulates dendritic cell differentiation and functional maturation from human peripheral blood CD14+ monocytes
  83. Effects of Pentoxifylline on Differentiation, Maturation, and Function of Human CD14+ Monocyte-derived Dendritic Cells
  84. C‐reactive protein impairs human CD14+ monocyte‐derived dendritic cell differentiation, maturation and function
  85. CD40 ligand increases expression of its receptor CD40 in human coronary artery endothelial cells
  86. Adiponectin promotes endothelial cell differentiation from human peripheral CD14+monocytesin vitro
  87. Acceleration of endothelial-like cell differentiation from CD14+ monocytes in vitro
  88. Transfection of SSTR-1 and SSTR-2 Inhibits Panc-1 Cell Proliferation and Renders Panc-1 Cells Responsive to Somatostatin Analogue
  89. Effects of Cyclophilin A on Myeloblastic Cell Line KG-1 Derived Dendritic Like Cells (DLC) Through p38 MAP Kinase Activation1,2
  90. Expression and regulation of neuropilins and VEGF receptors byTNF-α in human endothelial cells
  91. SHIV virus-like particles bind and activate human dendritic cells
  92. Th Cell-Independent Immune Responses to Chimeric Hemagglutinin/Simian Human Immunodeficiency Virus-Like Particles Vaccine
  93. Homodimerization through coiled‐coil regions enhances activity of the myotonic dystrophy protein kinase
  94. Myotonic dystrophy protein kinase phosphorylates the myosin phosphatase targeting subunit and inhibits myosin phosphatase activity