All Stories

  1. Mannitol reduces the time to reconstitute protein drug medication
  2. Protein Internal Dynamics Associated With Pre–System Glass Transition Temperature Endothermic Events: Investigation of Insulin and Human Growth Hormone by Solid State Hydrogen/Deuterium Exchange
  3. Freeze-Drying Process Development and Scale-Up: Scale-Up of Edge Vial Versus Center Vial Heat Transfer Coefficients, Kv
  4. Spatial Variation of Pressure in the Lyophilization Product Chamber Part 1: Computational Modeling
  5. Spatial Variation of Pressure in the Lyophilization Product Chamber Part 2: Experimental Measurements and Implications for Scale-up and Batch Uniformity
  6. Addition of Amino Acids to Further Stabilize Lyophilized Sucrose-Based Protein Formulations: I. Screening of 15 Amino Acids in Two Model Proteins
  7. Mathematical Models to Explore Potential Effects of Supersaturation and Precipitation on Oral Bioavailability of Poorly Soluble Drugs
  8. Amorphization of itraconazole by inorganic pharmaceutical excipients: comparison of excipients and processing methods
  9. Optimization of a Raman Microscopy Technique to Efficiently Detect Amorphous–Amorphous Phase Separation in Freeze‐Dried Protein Formulations
  10. Systematic Investigation of Parameters Affecting the Performance of an Agitated Filter-Dryer
  11. Solution-Mediated Phase Transformation: Significance During Dissolution and Implications for Bioavailability
  12. Spontaneous Crystalline-to-Amorphous Phase Transformation of Organic or Medicinal Compounds in the Presence of Porous Media, Part 3: Effect of Moisture
  13. ChemInform Abstract: Aqueous Solubility of Crystalline and Amorphous Drugs: Challenges in Measurement
  14. Application of Mesoporous Silicon Dioxide and Silicate in Oral Amorphous Drug Delivery Systems
  15. Spontaneous crystalline‐to‐amorphous phase transformation of organic or medicinal compounds in the presence of porous media, part 2: Amorphization capacity and mechanisms of interaction
  16. Solubility Advantage of Amorphous Pharmaceuticals, Part 3: Is Maximum Solubility Advantage Experimentally Attainable and Sustainable?
  17. Solution-Mediated Phase Transformation of Haloperidol Mesylate in the Presence of Sodium Lauryl Sulfate
  18. Solution-Mediated Phase Transformation of Salts During Dissolution: Investigation Using Haloperidol as a Model Drug
  19. Spontaneous Crystalline-to-Amorphous Phase Transformation of Organic or Medicinal Compounds in the Presence of Porous Media, Part 1: Thermodynamics of Spontaneous Amorphization
  20. Complex Effects of Drug/Silicate Ratio, Solid-State Equivalent pH, and Moisture on Chemical Stability of Amorphous Quinapril Hydrochloride Coground with Silicates
  21. The Study of Phase Separation in Amorphous Freeze-Dried Systems. Part I: Raman Mapping and Computational Analysis of XRPD Data in Model Polymer Systems
  22. Crystallization of Amorphous Indomethacin during Dissolution: Effect of Processing and Annealing
  23. Factors Affecting Calcium Precipitation During Neutralisation in a Simulated Intestinal Environment
  24. Solubility Advantage of Amorphous Pharmaceuticals: II. Application of Quantitative Thermodynamic Relationships for Prediction of Solubility Enhancement in Structurally Diverse Insoluble Pharmaceuticals
  25. Pharmaceutical review articles: From good to great
  26. Differential heat of adsorption of water vapor on silicified microcrystalline cellulose (SMCC): An investigation using isothermal microcalorimetry
  27. Solventless visible light-curable coating: I. Critical formulation and processing parameters
  28. Solventless visible light-curable coating: II. Drug release, mechanical strength and photostability
  29. Solid-State Surface Acidity and pH-Stability Profiles of Amorphous Quinapril Hydrochloride and Silicate Formulations
  30. Aqueous solubility of crystalline and amorphous drugs: Challenges in measurement
  31. Solubility advantage of amorphous pharmaceuticals: I. A thermodynamic analysis
  32. Design and characterization of a laminar flow-through dissolution apparatus: Comparison of hydrodynamic conditions to those of common dissolution techniques
  33. Effect of the pH grade of silicates on chemical stability of coground amorphous quinapril hydrochloride and its stabilization using pH-modifiers
  34. Exploration of Intestinal Calcium Precipitation as a Barrier to Absorption at High Calcium Doses
  35. Study of the Individual Contributions of Ice Formation and Freeze-Concentration on Isothermal Stability of Lactate Dehydrogenase during Freezing
  36. Amorphization Alone Does Not Account for the Enhancement of Solubility of Drug Co-ground with Silicate: The Case of Indomethacin
  37. Comparison of the Ability of Various Pharmaceutical Silicates to Amorphize and Enhance Dissolution of Indomethacin Upon Co-grinding
  38. Determination of calcium salt solubility with changes in pH and PCO2, simulating varying gastrointestinal environments
  39. Solventless photocurable film coating: Evaluation of drug release, mechanical strength, and photostability
  40. The Effect of Annealing on the Stability of Amorphous Solids: Chemical Stability of Freeze-Dried Moxalactam
  41. Solventless Pharmaceutical Coating Processes: A Review
  42. Protein Stability During Freezing: Separation of Stresses and Mechanisms of Protein Stabilization
  43. Design space for a solventless photocurable pharmaceutical coating
  44. Amorphization of Indomethacin by Co-Grinding with Neusilin US2: Amorphization Kinetics, Physical Stability and Mechanism
  45. Post-Thaw Aging Affects Activity of Lactate Dehydrogenase
  46. Reliable determination of freeze-concentration using DSC
  47. Formation of Physically Stable Amorphous Drugs by Milling with Neusilin
  48. Measurement of pH near dissolving enteric coatings
  49. Mechanism for Further Enhancement in Drug Dissolution from Solid-Dispersion Granules upon Storage
  50. Enhanced Drug Dissolution and Bulk Properties of Solid Dispersions Granulated with a Surface Adsorbent
  51. Correction for the dielectric constant of pH values in heterogeneous solutions obtained from fluorescein fluorescence
  52. Sensitivity and selectivity of p-(N-dimethylamino cinnamylidene) malononitrile, 6-propionyl-2-(dimethylamino) naphthalene (PRODAN) and fluorescein
  53. Development of a Course to Promote Research Awareness in Pharmacy Students
  54. Experimental evidence for the development of a microviscous layer near the surface of dissolving polyethylene glycol
  55. Investigation of Physicochemical Changes to l-Asparaginase During Freeze-thaw Cycling
  56. Techniques to monitor the UV curing of potential solvent-free film-coating polymers
  57. Kinetics of curing and physicomechanical behavior of silicone membrane
  58. Methods for determining partial solubility parameters of potential film-coating polymers