All Stories

  1. Multispectral live-cell imaging with uncompromised spatiotemporal resolution

    Article • Nature Precedings, September 2025, Springer Science + Business Media

    Dr Robert R Kay

  2. Making cups and rings: the ‘stalled-wave’ model for macropinocytosis

    Article • Biochemical Society Transactions, June 2024, Portland Press Ltd.

    Dr Robert R Kay

  3. Formation and closure of macropinocytic cups in Dictyostelium

    Article • Current Biology, August 2023, Elsevier

    Dr Robert R Kay

  4. Jeffrey G. Williams (1948-2022): a pioneer molecular biologist in development

    Article • Development, October 2022, The Company of Biologists

    Dr Cornelis jan Weijer, Dr Robert R Kay

  5. Generating polyketide diversity in Dictyostelium : a Steely hybrid polyketide synthase produces alternate products at different developmental stages

    Article • Proceedings of the Royal Society B Biological Sciences, September 2022, Royal Society Publishing

    Dr Robert R Kay

  6. Macropinocytosis: Biology and mechanisms

    Article • Cells and Development, December 2021, Elsevier

    Dr Robert R Kay

  7. Endocytosis: RasGAPs Help Organize Macropinocytic Cups

    Article • Current Biology, August 2020, Elsevier

    Dr Robert R Kay

  8. Pressure sensing through Piezo channels controls whether cells migrate with blebs or pseudopods

    Article • Proceedings of the National Academy of Sciences, January 2020, Proceedings of the National Academy of Sciences

    Dr Robert R Kay

  9. The Atypical MAP Kinase ErkB Transmits Distinct Chemotactic Signals through a Core Signaling Module

    Article • Developmental Cell, February 2019, Elsevier

    Dr Robert R Kay

  10. Triparental inheritance in Dictyostelium

    Article • Proceedings of the National Academy of Sciences, January 2019, Proceedings of the National Academy of Sciences

    Dr Robert R Kay

  11. Akt and SGK protein kinases are required for efficient feeding by macropinocytosis

    Article • Journal of Cell Science, January 2019, The Company of Biologists

    Dr Robert R Kay

  12. Living on soup: macropinocytic feeding in amoebae

    Article • The International Journal of Developmental Biology, January 2019, UBC Press

    Dr Robert R Kay

  13. Function of small GTPases in Dictyostelium macropinocytosis

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, December 2018, Royal Society Publishing

    Dr Robert R Kay

  14. The origins and evolution of macropinocytosis

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, December 2018, Royal Society Publishing

    Dr Robert R Kay

  15. Rapid and efficient genetic engineering of both wild type and axenic strains of Dictyostelium discoideum

    Article • PLOS One, May 2018, PLOS

    Profesor Robert Insall, Dr Robert R Kay

  16. Repellent and Attractant Guidance Cues Initiate Cell Migration by Distinct Rear-Driven and Front-Driven Cytoskeletal Mechanisms

    Article • Current Biology, March 2018, Elsevier

    Dr Robert R Kay

  17. The physiological regulation of macropinocytosis during Dictyostelium growth and development

    Article • Journal of Cell Science, February 2018, The Company of Biologists

    Dr Robert R Kay

  18. The physiological regulation of macropinocytosis during Dictyostelium growth and development

    Article • December 2017, Cold Spring Harbor Laboratory Press

    Dr Robert R Kay

  19. Image based modeling of bleb site selection

    Article • Scientific Reports, July 2017, Springer Science + Business Media

    Dr Robert R Kay

  20. A polycystin-type transient receptor potential (Trp) channel that is activated by ATP

    Article • Biology Open, December 2016, The Company of Biologists

    Dr Robert R Kay

  21. A plasma membrane template for macropinocytic cups

    Article • eLife, December 2016, eLife

    Profesor Robert Insall, Dr Robert R Kay

  22. Mechanism of eIF6 release from the nascent 60S ribosomal subunit

    Article • Nature Structural & Molecular Biology, October 2015, Springer Science + Business Media

    Dr Robert R Kay

  23. Chemotaxis of a model organism: progress with Dictyostelium

    Article • Current Opinion in Cell Biology, October 2015, Elsevier

    Dr Robert R Kay

  24. Neurofibromin controls macropinocytosis and phagocytosis in Dictyostelium

    Article • eLife, March 2015, eLife

    Dr Robert R Kay

  25. Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion

    Article • EMBO Molecular Medicine, December 2014, EMBO

    Dr Robert R Kay

  26. Dictyostelium uses ether-linked inositol phospholipids for intracellular signalling

    Article • The EMBO Journal, September 2014, EMBO

    Dr Robert R Kay

  27. How blebs and pseudopods cooperate during chemotaxis

    Article • Proceedings of the National Academy of Sciences, July 2014, Proceedings of the National Academy of Sciences

    Dr Robert R Kay

  28. Characterization of TSET, an ancient and widespread membrane trafficking complex

    Article • eLife, May 2014, eLife

    Joel Dacks, Dr Robert R Kay

  29. Bleb-driven chemotaxis of Dictyostelium cells

    Article • Journal of Cell Biology, March 2014, Rockefeller University Press

    Dr Robert R Kay

  30. A PIP5 Kinase Essential for Efficient Chemotactic Signaling

    Article • Current Biology, February 2014, Elsevier

    Dr Robert R Kay

  31. Two distinct functions for PI3-kinases in macropinocytosis

    Article • Journal of Cell Science, July 2013, The Company of Biologists

    Dr Robert R Kay

  32. Defective ribosome assembly in Shwachman-Diamond syndrome

    Article • Blood, October 2011, American Society of Hematology

    Dr Robert R Kay

  33. Identification of a Eukaryotic Reductive Dechlorinase and Characterization of Its Mechanism of Action on Its Natural Substrate

    Article • Chemistry & Biology, October 2011, Elsevier

    Dr Robert R Kay

  34. Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum

    Article • Genome Biology, January 2011, Springer Science + Business Media

    Professor Ludwig Eichinger, Dr Robert R Kay

  35. Sex Determination in the Social Amoeba Dictyostelium discoideum

    Article • Science, December 2010, American Association for the Advancement of Science

    Dr Robert R Kay

  36. Dictyostelium

    Article • Current Biology, December 2010, Elsevier

    Dr Robert R Kay

  37. The exocytic gene secA is required for Dictyostelium cell motility and osmoregulation

    Article • Journal of Cell Science, August 2010, The Company of Biologists

    Dr Robert R Kay

  38. A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1

    Article • Proceedings of the National Academy of Sciences, March 2010, Proceedings of the National Academy of Sciences

    Dr Robert R Kay

  39. A new Dictyostelium prestalk cell sub-type

    Article • Developmental Biology, March 2010, Elsevier

    Dr Robert R Kay

  40. Xpf and Not the Fanconi Anaemia Proteins or Rev3 Accounts for the Extreme Resistance to Cisplatin in Dictyostelium discoideum

    Article • PLoS Genetics, September 2009, PLOS

    Dr Robert R Kay

  41. Migration ofDictyosteliumslugs: Anterior-like cells may provide the motive force for the prespore zone

    Article • Cell Motility and the Cytoskeleton, August 2009, Wiley

    Dr Robert R Kay

  42. Forming Patterns in Development without Morphogen Gradients: Scattered Differentiation and Sorting Out

    Article • Cold Spring Harbor Perspectives in Biology, July 2009, Cold Spring Harbor Laboratory Press

    Dr Robert R Kay

  43. Regulation of Rap1 activity is required for differential adhesion, cell-type patterning and morphogenesis in Dictyostelium

    Article • Journal of Cell Science, January 2009, The Company of Biologists

    Dr Robert R Kay

  44. Surface area regulation: underexplored yet crucial in cell motility

    Article • Nature Reviews Molecular Cell Biology, August 2008, Springer Science + Business Media

    Dr Robert R Kay

  45. Changing directions in the study of chemotaxis

    Article • Nature Reviews Molecular Cell Biology, June 2008, Springer Science + Business Media

    Dr Robert R Kay

  46. DIF-1 induces the basal disc of the Dictyostelium fruiting body

    Article • Developmental Biology, May 2008, Elsevier

    Dr Robert R Kay

  47. SrfB, a member of the Serum Response Factor family of transcription factors, regulates starvation response and early development in Dictyostelium

    Article • Developmental Biology, April 2008, Elsevier

    Dr Leandro Sastre, Dr Robert R Kay

  48. Dictyostelium transcriptional responses to Pseudomonas aeruginosa: common and specific effects from PAO1 and PA14 strains

    Article • BMC Microbiology, January 2008, Springer Science + Business Media

    Dr Robert R Kay

  49. Widespread duplications in the genomes of laboratory stocks of Dictyostelium discoideum

    Article • Genome Biology, January 2008, Springer Science + Business Media

    Dr Robert R Kay

  50. Possible roles of the endocytic cycle in cell motility

    Article • Journal of Cell Science, July 2007, The Company of Biologists

    Dr Robert R Kay

  51. Mutants in the Dictyostelium Arp2/3 complex and chemoattractant-induced actin polymerization

    Article • Experimental Cell Research, July 2007, Elsevier

    Dr Robert R Kay

  52. Chemotaxis in the Absence of PIP3 Gradients

    Article • Current Biology, May 2007, Elsevier

    Dr Robert R Kay

  53. A new environmentally resistant cell type from Dictyostelium

    Article • Microbiology, February 2007, Society for General Microbiology

    Dr Robert R Kay

  54. My 2,000 best films: parallel phenotyping of Dictyostelium development

    Article • Genome Biology, January 2007, Springer Science + Business Media

    Dr Robert R Kay

  55. Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid–type III polyketide synthase

    Article • Nature Chemical Biology, August 2006, Springer Science + Business Media

    Dr Robert R Kay

  56. Blebbing of Dictyostelium cells in response to chemoattractant

    Article • Experimental Cell Research, July 2006, Elsevier

    Dr Robert R Kay

  57. Identification of new differentiation inducing factors from Dictyostelium discoideum

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, May 2006, Elsevier

    Dr Robert R Kay

  58. Developmental timing in Dictyostelium is regulated by the Set1 histone methyltransferase

    Article • Developmental Biology, April 2006, Elsevier

    Dr Robert R Kay

  59. New prestalk and prespore inducing signals in Dictyostelium

    Article • Developmental Biology, June 2005, Elsevier

    Dr Robert R Kay

  60. The genome of the social amoeba Dictyostelium discoideum

    Article • Nature, May 2005, Springer Science + Business Media

    Dr Robert R Kay

  61. A demonstration of pattern formation without positional information in Dictyostelium

    Article • Embryologia, August 2004, Wiley

    Dr Robert R Kay

  62. Novel Development Rescuing Factors (DRFs) Secreted by the Developing Dictyostelium Cells, That are Involved in the Restoration of a Mutant Lacking MAP-kinase ERK2

    Article • ZOOLOGICAL SCIENCE, August 2004, Zoological Society of Japan

    Dr Robert R Kay

  63. A bZIP/bRLZ transcription factor required for DIF signaling in Dictyostelium

    Article • Development, January 2004, The Company of Biologists

    Dr Robert R Kay

  64. Chemotaxis and cell differentiation in Dictyostelium

    Article • Current Opinion in Microbiology, December 2002, Elsevier

    Dr Robert R Kay

  65. The Role of DIF-1 Signaling in Dictyostelium Development

    Article • Molecular Cell, December 2000, Elsevier

    Dr Robert R Kay

  66. Cell-Fate Choice in Dictyostelium: Intrinsic Biases Modulate Sensitivity to DIF Signaling

    Article • Developmental Biology, November 2000, Elsevier

    Dr Robert R Kay

  67. DIF signalling and cell fate

    Article • Seminars in Cell and Developmental Biology, December 1999, Elsevier

    Dr Robert R Kay

  68. The RdeA-RegA System, a Eukaryotic Phospho-relay Controlling cAMP Breakdown

    Article • Journal of Biological Chemistry, September 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Robert R Kay

  69. The Dictyostelium genome project an invitation to species hopping

    Article • Trends in Genetics, August 1999, Elsevier

    Dr Robert R Kay

  70. Taking the plunge: terminal differentiation in Dictyostelium

    Article • Trends in Genetics, January 1999, Elsevier

    Dr Robert R Kay

  71. An intersection of the cAMP/PKA and two-component signal transduction systems in Dictyostelium

    Article • The EMBO Journal, May 1998, Wiley

    Dr Robert R Kay

  72. The Biosynthesis of Differentiation-Inducing Factor, a Chlorinated Signal Molecule RegulatingDictyosteliumDevelopment

    Article • Journal of Biological Chemistry, January 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Robert R Kay

  73. Glycogen synthase kinase 3 regulates cell fate in dictyostelium

    Article • Cell, January 1995, Elsevier

    Dr Robert R Kay

  74. Metabolic pathways for differentiation-inducing factor-1 and their regulation are conserved between closely related Dictyostelium species, but not between distant members of the family

    Article • Differentiation, January 1995, Elsevier

    Dr Robert R Kay

  75. Differentiation and patterning in Dictyostelium

    Article • Current Opinion in Genetics & Development, October 1994, Elsevier

    Dr Robert R Kay

  76. Morphogenesis and differentiation of Dictyostelium cells interacting with immobilized glucosides: dependence on DIF production

    Article • Differentiation, April 1992, Elsevier

    Dr Robert R Kay

  77. New roles for DIF? Effects on early development in Dictyostelium

    Article • Developmental Biology, July 1990, Elsevier

    Dr Robert R Kay

  78. Position-Dependent regulation of the prestalk-prespore pattern inDictyostelium slugs

    Article • Developmental Genetics, January 1990, Wiley

    Dr Robert R Kay

  79. Origins of the prestalk-prespore pattern in Dictyostelium development

    Article • Cell, December 1989, Elsevier

    Dr Robert R Kay

  80. Cyclic AMP is an inhibitor of stalk cell differentiation in Dictyostelium discoideum

    Article • Developmental Biology, March 1988, Elsevier

    Dr Robert R Kay

  81. Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum

    Article • Nature, August 1987, Springer Science + Business Media

    Dr Robert R Kay

  82. Direct induction of dictyostelium prestalk gene expression by DIF provides evidence that DIF is a morphogen

    Article • Cell, April 1987, Elsevier

    Dr Robert R Kay

  83. Chapter 23 Cell Differentiation in Monolayers and the Investigation of Slime Mold Morphogens

    Article • January 1987, Elsevier

    Dr Robert R Kay

  84. Gene targeting in Dictyostelium: what do cells need myosin for?

    Article • Trends in Genetics, January 1987, Elsevier

    Dr Robert R Kay

  85. An electrogenic proton pump in plasma membranes from the cellular slime mould Dictyostelium discoideum

    Article • FEBS Letters, October 1984, Wiley

    Dr Robert R Kay

  86. Dictyostelium mutants lacking DIF, a putative morphogen

    Article • Cell, June 1983, Elsevier

    Dr Robert R Kay

  87. Control of gene expression: Cyclic AMP and development in the slime mould

    Article • Nature, February 1983, Springer Science + Business Media

    Dr Robert R Kay

  88. Developmental regulation of a stalk cell differentiation-inducing factor in Dictyostelium discoideum

    Article • Developmental Biology, May 1982, Elsevier

    Dr Robert R Kay

  89. How cells live together

    Article • Nature, November 1981, Springer Science + Business Media

    Dr Robert R Kay

  90. Effects of BUdR on developmental functions of Dictyostelium discoideum

    Article • Cell Differentiation, April 1978, Elsevier

    Dr Robert R Kay

  91. Erratum

    Article • Nature, February 1978, Springer Science + Business Media

    Dr Robert R Kay

  92. Repetitive DNA associated with rodent liver nuclear envelopes

    Article • Cellular and Molecular Life Sciences, May 1974, Springer Science + Business Media

    Dr Robert R Kay

  93. Late replication of the DNA associated with the nuclear membrane

    Article • FEBS Letters, September 1971, Wiley

    Dr Robert R Kay

  94. Abstract

    Article • eLife

    Dr Robert R Kay