All Stories

  1. Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology
  2. Decorin deficiency promotes hepatic carcinogenesis
  3. De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways
  4. Biglycan and decorin differentially regulate signaling in the fetal membranes
  5. Decorin differentially modulates the activity of insulin receptor isoform A ligands
  6. A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function
  7. Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells
  8. The injury response of aged tendons in the absence of biglycan and decorin
  9. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling
  10. Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury
  11. Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells
  12. Matrix Biologists in Action
  13. Announcement – MBE Meeting
  14. Osteoblastic cell secretome: A novel role for progranulin during risedronate treatment
  15. ELAF posters
  16. Decorin has an appetite for endothelial cell autophagy
  17. The location-specific role of proteoglycans in the flexor carpi ulnaris tendon
  18. The Tendon Injury Response is Influenced by Decorin and Biglycan
  19. 11C-meta-hydroxyephedrine PET/CT imaging allows in vivo study of adaptive thermogenesis and white-to-brown fat conversion
  20. Intracellularly-Retained Decorin Lacking the C-Terminal Ear Repeat Causes ER Stress
  21. Heparanase: Multiple functions in inflammation, diabetes and atherosclerosis
  22. Decorin interferes with platelet‐derived growth factor receptor signaling in experimental hepatocarcinogenesis
  23. Endorepellin laminin‐like globular 1/2 domains bind Ig3–5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro‐angiogenic signaling by VEGFA in endothelial cells
  24. Biological interplay between proteoglycans and their innate immune receptors in inflammation
  25. Dichotomy of decorin activity on the insulin‐like growth factor‐I system
  26. Decorin induces rapid secretion of thrombospondin‐1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho‐associated coiled‐coil containing protein kinase 1
  27. Effect of Age and Proteoglycan Deficiency on Collagen Fiber Re-Alignment and Mechanical Properties in Mouse Supraspinatus Tendon
  28. Decorin expression is important for age-related changes in tendon structure and mechanical properties
  29. Obesity and Diabetes
  30. The Dermatan Sulfate Proteoglycan Decorin Modulates α2β1 Integrin and the Vimentin Intermediate Filament System during Collagen Synthesis
  31. Decorin Protein Core Affects the Global Gene Expression Profile of the Tumor Microenvironment in a Triple-Negative Orthotopic Breast Carcinoma Xenograft Model
  32. 3.5 Small leucine-rich proteoglycans: multifunctional signaling effectors
  33. 3.4 The biology of perlecan and its bioactive modules
  34. Decorin
  35. Proline-Rich Tyrosine Kinase 2 (Pyk2) Regulates IGF-I-Induced Cell Motility and Invasion of Urothelial Carcinoma Cells
  36. Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation
  37. Targeting heparanase for cancer therapy at the tumor–matrix interface
  38. Thrombospondins in physiology and disease: New tricks for old dogs
  39. Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation
  40. Decorin–TGFβ Axis in Hepatic Fibrosis and Cirrhosis
  41. Uterine Dysfunction in Biglycan and Decorin Deficient Mice Leads to Dystocia during Parturition
  42. Influence of Decorin on the Mechanical, Compositional, and Structural Properties of the Mouse Patellar Tendon
  43. Pathophysiological Mechanisms of Autosomal Dominant Congenital Stromal Corneal Dystrophy
  44. Autophagic tumor stroma: A biofuel for cancer growth
  45. Scleroderma-like properties of skin from caveolin-1-deficient mice
  46. Influence of Decorin and Biglycan on Tensile Viscoelastic Properties in Knockout Mice
  47. Mitostatin Is Down-Regulated in Human Prostate Cancer and Suppresses the Invasive Phenotype of Prostate Cancer Cells
  48. Proteoglycans in cancer biology, tumour microenvironment and angiogenesis
  49. Myocardial, Perivascular, and Epicardial Fat
  50. Ablation of the decorin gene enhances experimental hepatic fibrosis and impairs hepatic healing in mice
  51. Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment
  52. Small Leucine-Rich Proteoglycans
  53. Proteoglycans in health and disease: emerging concepts and future directions
  54. Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine‐rich proteoglycans
  55. Letter from Renato V. Iozzo
  56. Heparan Sulfate-Dependent Signaling of Fibroblast Growth Factor 18 by Chondrocyte-Derived Perlecan
  57. The Insulin-Like Growth Factor Receptor I Promotes Motility and Invasion of Bladder Cancer Cells through Akt- and Mitogen-Activated Protein Kinase-Dependent Activation of Paxillin
  58. Metabolic toxicity of the heart: Insights from molecular imaging
  59. Necrotizing vasculitis in a patient affected by autoimmune hyperthyroidism treated with propylthiouracil
  60. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan
  61. Collagen fibril organization in the pregnant endometrium of decorin‐deficient mice
  62. Viewpoints on the Way to the Consensus Session
  63. A Key Role for the Integrin α2β1 in Experimental and Developmental Angiogenesis
  64. Topographical variation in the distributions of versican, aggrecan and perlecan in the foetal human spine reflects their diverse functional roles in spinal development
  65. Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis
  66. Basement Membrane Proteoglycans: Modulators Par Excellence of Cancer Growth and Angiogenesis
  67. PROEPITHELIN IS A NOVEL BIOMARKER FOR PROSTATE CANCER AND REGULATES CELL GROWTH, MIGRATION AND ANCHORAGE-INDEPENDENT GROWTH OF PROSTATE CANCER CELLS
  68. Genetic evidence for key roles of decorin and biglycan in dentin mineralization
  69. Proepithelin Regulates Prostate Cancer Cell Biology by Promoting Cell Growth, Migration, and Anchorage-Independent Growth
  70. A central role for decorin during vertebrate convergent extension
  71. Endorepellin evokes SHP1 activity in endothelial cells
  72. Decorin binds to and downregulates the MET receptor
  73. Small molecule inhibitors of collagen-induced angiogenesis
  74. Diverse Cell Signaling Events Modulated by Perlecan
  75. Tumor microenvironment: Modulation by decorin and related molecules harboring leucine‐rich tandem motifs
  76. An Antimetastatic Role for Decorin in Breast Cancer
  77. Urinary proteomic analysis of chronic allograft nephropathy
  78. Influence of cyclic strain and decorin deficiency on 3D cellularized collagen matrices
  79. MITOSTATIN, A NOVEL MITOCHONDRIAL PROTEIN, THAT ACTS AS A TUMOR SUPPRESSOR IN PROSTATE CANCER CELLS
  80. Novel interactions of perlecan: Unraveling perlecan's role in angiogenesis
  81. Recombinant heparan sulfate for use in tissue engineering applications
  82. Proteomic profiling of endorepellin angiostatic activity on human endothelial cells
  83. Decorin Deficiency Enhances Progressive Nephropathy in Diabetic Mice
  84. The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis
  85. Positron Emission Tomography in Metabolic Research
  86. Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice
  87. Decorin-Mediated Regulation of Fibrillin-1 in the Kidney Involves the Insulin-Like Growth Factor-I Receptor and Mammalian Target of Rapamycin
  88. Soluble LRIG1 inhibits cancer cell growth
  89. Actin' Up: Endorepellin and endothelial morphogenesis
  90. Endothelial cell_collagen interactions in angiogenesis
  91. A role for decorin in cutaneous wound healing and angiogenesis
  92. Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development
  93. The role of proteomics in the assessment of premature rupture of fetal membranes
  94. Heparan Sulfate: A Complex Polymer Charged with Biological Activity
  95. Basement membrane proteoglycans: from cellar to ceiling
  96. A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival
  97. Heparan Sulfate:  A Complex Polymer Charged with Biological Activity
  98. Matrix revolutions: ‘tails’ of basement-membrane components with angiostatic functions
  99. Influence of Decorin and Biglycan on Mechanical Properties of Multiple Tendons in Knockout Mice
  100. Decorin prevents metastatic spreading of breast cancer
  101. Protective Niche for Borrelia burgdorferi to Evade Humoral Immunity
  102. Regulation of Fibrillin-1 by Biglycan and Decorin Is Important for Tissue Preservation in the Kidney During Pressure-Induced Injury
  103. Investigating Tendon Fascicle Structure–Function Relationships in a Transgenic-Age Mouse Model Using Multiple Regression Models
  104. Strain-Rate Sensitive Mechanical Properties of Tendon Fascicles From Mice With Genetically Engineered Alterations in Collagen and Decorin
  105. Decorin Deficiency Leads to Impaired Angiogenesis in Injured Mouse Cornea
  106. Effect of Altered Matrix Proteins on Quasilinear Viscoelastic Properties in Transgenic Mouse Tail Tendons
  107. Androgen receptor expression induces FGF2, FGF‐binding protein production, and FGF2 release in prostate carcinoma cells: Role of FGF2 in growth, survival, and androgen receptor down‐modulation
  108. Decorin suppresses tumor cell-mediated angiogenesis
  109. Renato V. Iozzo (ed): Proteoglycan protocols
  110. Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin
  111. The role of decorin in collagen fibrillogenesis and skin homeostasis
  112. Absence of Decorin Adversely Influences Tubulointerstitial Fibrosis of the Obstructed Kidney by Enhanced Apoptosis and Increased Inflammatory Reaction
  113. Isolation and purification of proteoglycans
  114. A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor
  115. Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena
  116. Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena
  117. Series Introduction: Heparan sulfate proteoglycans: intricate molecules with intriguing functions
  118. Series Introduction: Heparan sulfate proteoglycans: intricate molecules with intriguing functions
  119. Proteoglycan Protocols
  120. Proteoglycans: Structure, Biology, and Molecular Interactions Renato V. Iozzo
  121. Glycosaminoglycans: Structure and Biological Functions
  122. Resistance to Lyme disease in decorin-deficient mice
  123. A Role for Decorin in the Structural Organization of Periodontal Ligament
  124. Activation of extracellular signal-regulated protein kinase1,2 results in down-regulation of decorin expression in fibroblasts
  125. Proteoglycans
  126. Introductory Remarks and Overview
  127. Fibroblast growth factor-2
  128. Human perlecan immunopurified from different endothelial cell sources has different adhesive properties for vascular cells
  129. Decorin Is a Biological Ligand for the Epidermal Growth Factor Receptor
  130. Decorin, epiphycan, and lumican genes are closely linked on murine Chromosome 10 and are deleted in lethal steel mutants
  131. There Is Binding of Collagen IV to β1 Integrin during Early Skin Basement Membrane Assembly
  132. MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function
  133. Transcriptional and Posttranscriptional Regulation of Proteoglycan Gene Expression
  134. Ectopic expression of decorin protein core causes generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases
  135. Altered Proteoglycan Gene Expression in Human Biliary Cirrhosis
  136. The Family of the Small Leucine-Rich Proteoglycans: Key Regulators of Matrix Assembly and Cellular Growth
  137. The Murine Biglycan: Complete cDNA Cloning, Genomic Organization, Promoter Function, and Expression
  138. Expression Pattern and Mapping of the Murine Versican Gene (Cspg2) to Chromosome 13
  139. The proteoglycan perlecan is expressed in the erythroleukemia cell line K562 and is upregulated by sodium butyrate and phorbol ester
  140. Decorin gene transcription: Up-regulation upon cellular quiescence and down-regulation by tumor necrosis factor-α
  141. Formation of nodular structures resembling mature articular cartilage in long–term primary cultures of human fetal epiphyseal chondrocytes on a hydrogel substrate
  142. Perlecan: A gem of a proteoglycan
  143. ChemInform Abstract: Altered Proteoglycan Gene Expression and the Tumor Stroma
  144. Altered proteoglycan gene expression and the tumor stroma
  145. Molecular Cloning of the Human Proto-oncogene Wnt-5A and Mapping of the Gene (WNT5A) to Chromosome 3p14-p21
  146. Stimulation of protein synthesis in isolated pancreatic acini from chronically ethanol-fed rats is due to alterations in post-transcriptional regulation
  147. Perlecan: The multidomain heparan sulphate proteoglycan of basement membrane and extracellular matrix
  148. Altered proteoglycan gene expression and the tumor stroma
  149. The Human Decorin Gene: Intron-Exon Organization, Discovery of Two Alternatively Spliced Exons in the 5′ Untranslated Region, and Mapping of the Gene to Chromosome 12q23
  150. Mapping of the versican proteoglycan gene (CSPG2) to the long arm of human chromosome 5 (5q12–5q14)
  151. Establishment of a Cell Line from the EHS Tumor: Biosynthesis of Basement Membrane Constituents and Characterization of a Hybrid Proteoglycan Containing Heparan and Chondroitin Sulfate Chains
  152. Biosynthetic and proliferative characteristics of tubulointerstitial fibroblasts probed with paracrine cytokines
  153. Larsen's syndrome with novel congenital anomalies
  154. Human clathrin heavy chain (CLTC): Partial molecular cloning, expression, and mapping of the gene to human chromosome 17q11-qter
  155. Heparan sulfate proteoglycan of human colon: Partial molecular cloning, cellular expression, and mapping of the gene (HSPG2) to the short arm of human chromosome 1
  156. Lipid-Linked Heparan Sulfate Proteoglycan.
  157. Myristoylation of heparan sulfate proteoglycan and proteins occurs post-translationally in human colon carcinoma cells
  158. Altered methylation of versican proteoglycan gene in human colon carcinoma
  159. Inhibition of Proteoglycan Synthesis in Human Endothelial Cells after Infection with Herpes Simplex Virus Type 1In Vitro
  160. Altered glycosaminoglycan composition in reactive and neoplastic human liver
  161. Sequences
  162. Large animal model of left ventricular aneurysm
  163. Receptors for and bioresponses to 1,25-dihydroxyvitamin D in a human colon carcinoma cell line (HT-29)
  164. Bovine Pericardial Proteoglycan: Biochemical, Immunochemical and Ultrastructural Studies
  165. Heparin and endothelial cell growth factor modulate collagen and proteoglycan production in human smooth muscle cells
  166. Neoplastic modulation of extracellular matrix: Stimulation of chondroitin sulfate proteoglycan and hyaluronic acid synthesis in co‐cultures of human colon carcinoma and smooth muscle cells
  167. Identification of the precursor protein for the heparan sulfate proteoglycan of human colon carcinoma cells and its post-translational modifications
  168. Collagen matrix influences the morphologic features and steroid secretion of human granulosa cells
  169. Cell surface heparan sulfate proteoglycan and the neoplastic phenotype
  170. Proteoglycans and neoplasia
  171. Corinthian Basins on High Stands
  172. Experimental Myocardial Cryoinjury: Local Electromechanical Changes, Arrhythmogenicity, and Methods for Determining Depth of Injury
  173. Proteoglycans and the Intercellular Tumor Matrix
  174. Evidence of a small hydrophobic domain in the core protein of the heparan sulfate proteoglycan from human colon carcinoma cells
  175. MURCS association with additional congenital anomalies
  176. Early diagnosis of experimental necrotizing enterocolitis using proton nuclear magnetic resonance
  177. Anatomic and hemodynamic effects of catheter-delivered ablation energies in the ventricle
  178. Proteoglycans and neoplastic—mesenchymal cell interactions
  179. Analysis of proteoglycans by high-performance liquid chromatography: A rapid micromethod for the separation of proteoglycans from tissue and cell culture
  180. Cerebral infarction complicating umbilical vein catheterization
  181. Prokaryotic Expression of Proteoglycans
  182. Proteoglycan Gene Targeting in Somatic Cells
  183. Constitutive and Inducible Antisense Expression
  184. Interaction of Proteoglycans with Receptor Tyrosine Kinases
  185. Measuring Single-Cell Cytosolic Ca<sup>2+</sup> Concentration in Response to Proteoglycans