All Stories

  1. Recent advances in understanding and managing hepatic encephalopathy in chronic liver disease

    Article • F1000Research, April 2020, Faculty of 1000, Ltd.

    Professor Rajiv Jalan

  2. Novel therapies in the management of acute episodes of hepatic encephalopathy

    Article • Clinical Liver Disease, March 2017, Wiley

    Professor Rajiv Jalan

  3. Acute-on-Chronic Liver Failure: A Distinct Clinical Condition

    Article • Seminars in Liver Disease, May 2016, Thieme Publishing Group

    Professor Rajiv Jalan

  4. From the Editor’s desk...

    Article • Journal of Hepatology, July 2015, Elsevier

    Professor Rajiv Jalan

  5. From the Editor’s desk...

    Article • Journal of Hepatology, June 2015, Elsevier

    Professor Rajiv Jalan

  6. From the Editor’s desk…

    Article • Journal of Hepatology, May 2015, Elsevier

    Professor Rajiv Jalan

  7. Hepatic encephalopathy: New treatments

    Article • Clinical Liver Disease, May 2015, Wiley

    Professor Rajiv Jalan

  8. Emerging trends in hepatology: 30years of the Journal of Hepatology and 50years of EASL

    Article • Journal of Hepatology, April 2015, Elsevier

    Professor Rajiv Jalan

  9. Acute-on-chronic liver failure: A new syndrome that will re-classify cirrhosis

    Article • Journal of Hepatology, April 2015, Elsevier

    Professor Rajiv Jalan

  10. Acute-on-Chronic Liver Failure: Recent Concepts

    Article • Journal of Clinical and Experimental Hepatology, March 2015, Elsevier

    Professor Rajiv Jalan

  11. Attenuation of Congenital Portosystemic Shunt Reduces Inflammation in Dogs

    Article • PLoS ONE, February 2015, PLOS

    Professor Rajiv Jalan

  12. Hepatic encephalopathy in patients with acute decompensation of cirrhosis and acute-on-chronic liver failure

    Article • Journal of Hepatology, February 2015, Elsevier

    Professor Rajiv Jalan

  13. A Multi-Journal Partnership to Highlight Joint First-Authors of Manuscripts

    Article • Gastroenterology, February 2015, Elsevier

    Professor Rajiv Jalan

  14. A Multi-Journal Partnership to Highlight Joint First-Authors of Manuscripts

    Article • Journal of Hepatology, February 2015, Elsevier

    Professor Rajiv Jalan

  15. A multi-journal partnership to highlight joint first-authors of manuscripts

    Article • Gastrointestinal Endoscopy, February 2015, Elsevier

    Professor Rajiv Jalan

  16. Hepatic dimethylarginine-dimethylaminohydrolase1 is reduced in cirrhosis and is a target for therapy in portal hypertension

    Article • Journal of Hepatology, February 2015, Elsevier

    Professor Rajiv Jalan

  17. Acute-on-chronic liver failure

    Article • January 2015, Wiley

    Professor Rajiv Jalan

  18. A multi-journal partnership to highlight joint first-authors of manuscripts

    Article • Hepatology, January 2015, Wiley

    Professor Rajiv Jalan

  19. A multi-journal partnership to highlight joint first-authors of manuscripts

    Article • Gut, January 2015, BMJ

    Professor Rajiv Jalan

  20. Liver Support Systems

    Article • January 2015, Springer Science + Business Media

    Professor Rajiv Jalan

  21. Journal of Hepatology: The home of liver research

    Article • Journal of Hepatology, January 2015, Elsevier

    Professor Rajiv Jalan

  22. L-Ornithine phenylacetate reduces ammonia in pigs with acute liver failure through phenylacetylglycine formation: a novel ammonia-lowering pathway

    Article • AJP Gastrointestinal and Liver Physiology, September 2014, American Physiological Society

    Professor Rajiv Jalan

  23. Novel insights into ammonia-mediated neurotoxicity pointing to potential new therapeutic strategies

    Article • Hepatology, August 2014, Wolters Kluwer Health

    Professor Rajiv Jalan

  24. Effect of toll-like receptor 7 and 9 targeted therapy to prevent the development of hepatocellular carcinoma

    Article • Liver International, July 2014, Wiley

    Professor Rajiv Jalan

  25. Pharmacotherapy for hyperammonemia

    Article • Expert Opinion on Pharmacotherapy, July 2014, Informa Healthcare

    Professor Rajiv Jalan

  26. Inflammation and portal hypertension – The undiscovered country

    Article • Journal of Hepatology, July 2014, Elsevier

    Professor Rajiv Jalan

  27. ‘Hepatology’ on the move

    Article • Liver International, June 2014, Wiley

    Professor Rajiv Jalan

  28. Joan Cordoba Cordona (1964–2014): A dedicated clinician, great scientist, mentor, friend, collaborator, critic…

    Article • Journal of Hepatology, June 2014, Elsevier

    Professor Rajiv Jalan

  29. The brain in acute on chronic liver failure

    Article • Metabolic Brain Disease, May 2014, Springer Science + Business Media

    Professor Rajiv Jalan

  30. Obeticholic acid, a Farensoid-X receptor agonist, improves portal hypertension by two distinct pathways in cirrhotic rats

    Article • Hepatology, May 2014, Wolters Kluwer Health

    Professor Rajiv Jalan

  31. Systemic inflammation is associated with increased intrahepatic resistance and mortality in alcohol-related acute-on-chronic liver failure

    Article • Liver International, April 2014, Wiley

    Professor Rajiv Jalan

  32. P105 ACTIVATION OF SENESCENT GENES IN CHRONIC AND ACUTE-ON-CHRONIC LIVER FAILURE RAT BRAINS

    Article • Journal of Hepatology, April 2014, Elsevier

    Professor Rajiv Jalan

  33. P39 EVIDENCE THAT AMMONIA ACTS AS A DANGER ASSOCIATED MOLECULAR PATTERN (DAMP) AND SIGNALS THROUGH THE TOLL-LIKE RECEPTOR-4 (TLR4) PATHWAY

    Article • Journal of Hepatology, April 2014, Elsevier

    Professor Rajiv Jalan

  34. P24 L-ORNITHINE PHENYLACETATE REDUCES AMMONIA IN PIGS WITH ACUTE LIVER FAILURE THROUGH PHENYLACETYLGLYCINE FORMATION: A NOVEL AMMONIA-LOWERING PATHWAY

    Article • Journal of Hepatology, April 2014, Elsevier

    Professor Rajiv Jalan

  35. P28 EVIDENCE FOR INTRACELLULAR IMMUNOMODULATORY AND ANTIOXIDANT ACTION OF ALBUMIN TO PROVIDE ENDOTHELIAL PROTECTION IN LIVER FAILURE

    Article • Journal of Hepatology, April 2014, Elsevier

    Professor Rajiv Jalan

  36. O15 EFFECTS OF THE FXR AGONIST OBETICHOLIC ACID ON HEPATIC VENOUS PRESSURE GRADIENT (HVPG) IN ALCOHOLIC CIRRHOSIS: A PROOF OF CONCEPT PHASE 2A STUDY

    Article • Journal of Hepatology, April 2014, Elsevier

    Professor Rajiv Jalan

  37. O70 LIFETOUCH: A NOVEL REMOTE MONITORING DEVICE TO IDENTIFY PATIENTS WITH ADVANCED CIRRHOSIS MOST AT RISK OF DECOMPENSATION – A PROOF OF CONCEPT STUDY

    Article • Journal of Hepatology, April 2014, Elsevier

    Professor Rajiv Jalan

  38. P91 EFFECT OF TOLL-LIKE RECEPTOR 7 AND 9 TARGETED THERAPY TO PREVENT THE DEVELOPMENT OF HEPATOCELLULAR CARCINOMA

    Article • Journal of Hepatology, April 2014, Elsevier

    Professor Rajiv Jalan

  39. P340 ALBUMIN EXCHANGE AND ENDOTOXIN REMOVAL USING THE NOVEL UCL-LIVER DIALYSIS DEVICE (UCL-LDD) PROLONGS SURVIVAL IN ACETAMINOPHEN-INDUCED ACUTE LIVER FAILURE (ALF)

    Article • Journal of Hepatology, April 2014, Elsevier

    Professor Rajiv Jalan

  40. P36 ADMINISTRATION OF RECOMBINANT ALKALINE PHOSPHATASE PREVENTS DEVELOPMENT OF ACUTE ON CHRONIC LIVER FAILURE (ACLF) IN A RODENT BILE-DUCT LIGATION MODEL

    Article • Journal of Hepatology, April 2014, Elsevier

    Professor Rajiv Jalan

  41. P949 QUANTITATION AND LOCATION OF THE SEVERITY OF BRAIN EDEMA IN PATIENTS WITH ACUTE ON CHRONIC LIVER FAILURE AND HEPATIC ENCEPHALOPATHY

    Article • Journal of Hepatology, April 2014, Elsevier

    Professor Rajiv Jalan

  42. Brain lactate in hepatic encephalopathy: Friend or foe?

    Article • Journal of Hepatology, March 2014, Elsevier

    Professor Rajiv Jalan

  43. L-Ornithine Phenylacetate (OCR-002) Ameliorates Portal Hypertension by Modulating NFKB Driven Inflammatory Pathway in Cirrhosis

    Article • Journal of Clinical and Experimental Hepatology, March 2014, Elsevier

    Professor Rajiv Jalan

  44. Arterial ammonia levels in cirrhosis are determined by systemic and hepatic hemodynamics, and by organ function: a quantitative modelling study

    Article • Liver International, November 2013, Wiley

    Professor Rajiv Jalan

  45. Effective albumin concentration and cirrhosis mortality: From concept to reality

    Article • Journal of Hepatology, November 2013, Elsevier

    Professor Rajiv Jalan

  46. Treatment of hyperammonemia in liver failure

    Article • Current Opinion in Clinical Nutrition & Metabolic Care, November 2013, Wolters Kluwer Health

    Professor Rajiv Jalan

  47. Hemostasis in patients with acute kidney injury secondary to acute liver failure

    Article • Kidney International, July 2013, Elsevier

    Dr Alex Gatt, Professor Rajiv Jalan

  48. Reply to: “Acute-on-chronic liver failure – Its definition remains unclear”

    Article • Journal of Hepatology, July 2013, Elsevier

    Professor Rajiv Jalan

  49. Role of Toll-Like Receptor 4 in Mediating Multiorgan Dysfunction in Mice With Acetaminophen Induced Acute Liver Failure

    Article • Liver Transplantation, June 2013, Wiley

    Professor Rajiv Jalan

  50. Cracking the ENCODE: From transcription to therapeutics

    Article • Hepatology, June 2013, Wiley

    Professor Rajiv Jalan

  51. When to use renal replacement therapy and bioartificial support for renal failure in patients with cirrhosis

    Article • Clinical Liver Disease, June 2013, Wiley

    Professor Rajiv Jalan

  52. Albumin: Pathophysiologic basis of its role in the treatment of cirrhosis and its complications

    Article • Hepatology, May 2013, Wiley

    Professor Rajiv Jalan

  53. Beyond scoring: a modern interpretation of disease progression in chronic liver disease

    Article • Gut, May 2013, BMJ

    Professor Rajiv Jalan

  54. 571 P2X7 RECEPTOR IN ACUTE KIDNEY INJURY OF CIRRHOSIS: A POTENTIAL NOVEL TARGET OF THERAPY

    Article • Journal of Hepatology, April 2013, Elsevier

    Professor Rajiv Jalan

  55. 578 ALBUMIN INFUSION IMPROVES SYSTEMIC AND RENAL BLOOD FLOW AUTOREGULATION BY RESTORATION OF ENDOTHELIAL DYSFUNCTION

    Article • Journal of Hepatology, April 2013, Elsevier

    Professor Rajiv Jalan

  56. 1064 TARGETING TLR7 AND 9: A NOVEL STRATEGY FOR TREATMENT OF CHOLANGIOCARCINOMA

    Article • Journal of Hepatology, April 2013, Elsevier

    Professor Rajiv Jalan

  57. 77 EMBOLIZATION OF LARGE SPONTANEOUS PORTOSYSTEMIC SHUNTS FOR REFRACTORY HEPATIC ENCEPHALOPATHY: A EUROPEAN MULTI-CENTER SURVEY ON SAFETY & EFFICACY

    Article • Journal of Hepatology, April 2013, Elsevier

    Professor Rajiv Jalan

  58. 534 MUSCLE GLUTAMINE SYNTHASE REGULATES THE SEVERITY OF HYPERAMMONEMIA, HEPATIC INFLAMMATION, BRAIN SWELLING AND SURVIVAL IN ACETAMINOPHEN HEPATOTOXICITY

    Article • Journal of Hepatology, April 2013, Elsevier

    Professor Rajiv Jalan

  59. Ornithine phenylacetate revisited

    Article • Metabolic Brain Disease, March 2013, Springer Science + Business Media

    Professor Rajiv Jalan

  60. Activation of farnesoid X receptor (FXR) by its agonist int-747 restores hepatic endothelial NOS activity and lowers portal pressure in cirrhotic rats by modulating the DDAH-ADMA pathway

    Article • Journal of Clinical and Experimental Hepatology, March 2013, Elsevier

    Professor Rajiv Jalan

  61. An exciting time for Hepatology

    Article • Liver International, December 2012, Wiley

    Professor Rajiv Jalan

  62. Acute-on chronic liver failure

    Article • Journal of Hepatology, December 2012, Elsevier

    Professor Rajiv Jalan

  63. Evaluation of coagulation abnormalities in acute liver failure

    Article • Journal of Hepatology, October 2012, Elsevier

    Dr Alex Gatt, Professor Rajiv Jalan

  64. Reply to: “Is a liver biopsy necessary in alcoholic hepatitis?”

    Article • Journal of Hepatology, June 2012, Elsevier

    Professor Rajiv Jalan

  65. Neurological complications of acute liver failure: Pathophysiological basis of current management and emerging therapies

    Article • Neurochemistry International, June 2012, Elsevier

    Professor Rajiv Jalan

  66. PTU-010 Computational model predicts that portosystemic shunting is key to the development of hyperammonaemia in liver cirrhosis

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  67. OC-068 Albumin is central in mediating the cardio-renal dysfunction of cirrhosis: a study in analbuminaemic rats: Abstract OC-068 Figure 1

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  68. PTU-016 Albumin restores renal blood flow (RBF) autoregulation in patients with refractory ascites and acute-on-chronic liver failure (ACLF) through stabilisation of endothelial function: Abstract PTU-016 Figure 1

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  69. PMO-128 Effects of oral nanoporous carbon therapy in leptin null mice as a model of non-alcoholic steatohepatitis

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  70. PMO-127 Biological effects of oral nanoporous carbon in bile duct ligated rats

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  71. PTU-008 A reproducible, clinically-relevant, intensively-managed, pig model of acute liver failure for testing of therapies aimed to prolong survival

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  72. PMO-142 Evidence refuting the Trojan-horse hypothesis of brain swelling in acute liver failure: l-type glutaminase is exclusively neuronal: Abstract PMO-142 Figure 1

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  73. PTU-049 Modulation of toll-like receptor genes with selective gut decontamination in cirrhotic animals prevents the development of acute-on chronic liver failure (ACLF)

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  74. PWE-264 Blood lipidomic profiling of hepatocellular carcinoma in human and animal studies identifies lysophosphatidylcholine (24, 0, 0), a discriminatory biomarker

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  75. PWE-265 Plasma metabolite profiling in a rat model of hepatocellular carcinoma and the effects of co-administered antibiotics

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  76. PWE-267 Urinary TLR4: a novel biomarker to identify patients with acute kidney injury in patients with acute on chronic liver failure: Abstract PWE-267 Figure 1

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  77. OC-023 Extracorporeal liver support using UCL-arsenel reduces inflammation, improves haemodynamic function and increase survival time in a porcine paracetamol-induced acute liver failure model

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  78. PMO-092 TLR7 expression is increased in hepatocellular cancer (HCC) and its modulation is associated with alterations in tumour growth: a novel therapeutic target

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  79. PMO-091 TLR 9 inhibition: a novel target of therapy for primary liver cancer

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  80. PTU-030 Selective gut decomtamination reduces hepatic expression of toll-like receptor (TLR) 4 and development of cirrhosis but does not prevent development of hepatocellular carcinoma (HCC)

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  81. PMO-123 Gene transfer of dimethylarginine dimethylaminohydrolase-1 reduces portal pressure in a rodent model of cirrhosis

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  82. OC-066 Toll like receptor 4 antagonist prevents acetaminophen induced acute liver failure in mice: a novel therapeutic strategy

    Article • Gut, May 2012, BMJ

    Professor Rajiv Jalan

  83. Reply to: “The quest for the elusive factors that underpin neutrophil dysfunction in cirrhosis goes on”

    Article • Journal of Hepatology, May 2012, Elsevier

    Professor Rajiv Jalan

  84. Mechanistic biomarkers in acute liver injury: Are we there yet?

    Article • Journal of Hepatology, May 2012, Elsevier

    Professor Rajiv Jalan

  85. Prevention of acute kidney injury in a rodent model of cirrhosis following selective gut decontamination is associated with reduced renal TLR4 expression

    Article • Journal of Hepatology, May 2012, Elsevier

    Professor Rajiv Jalan

  86. 597 PERICYTE ACTIVATION AND CEREBRAL SEQULAE OF CIRRHOSIS

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  87. Albumin Regeneration for Extracorporeal Liver Support Using Prometheus: A Step in the Right Direction

    Article • Gastroenterology, April 2012, Elsevier

    Professor Rajiv Jalan

  88. 117 GENE DELIVERY OF DIMETHYLARGININE DIMETHYLAMINOHYDROLASE-1 REDUCES PORTAL PRESSURE IN BILE DUCT-LIGATED RATS

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  89. 595 INFLAMMATION UPREGULATES HEPATIC CONNEXIN-43 EXPRESSION IN CIRRHOSIS WHICH DEFINES SUSCEPTIBILITY TO DEVELOPMENT OF ACUTE-ON CHRONIC LIVER FAILURE

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  90. 588 ALBUMIN RESTORES RENAL BLOOD FLOW (RBF) AUTOREGULATION IN PATIENTS WITH REFRACTORY ASCITES AND ACUTE-ON-CHRONIC LIVER FAILURE (ACLF) THROUGH STABILIZATION OF ENDOTHELIAL FUNCTION

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  91. 1248 ORAL ADMINISTRATION OF NANOPOROUS CARBONS REDUCE SEVERITY OF NON-ALCOHOLIC STEATOHEPATITIS BY MODULATING HEPATIC KUPFFER CELL FUNCTION: A NOVEL THERAPEUTIC APPROACH

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  92. 577 ALBUMIN IS CENTRAL IN MEDIATING THE CARDIO-RENAL DYSFUNCTION OF CIRRHOSIS: A STUDY IN ANALBUMINAEMIC RATS

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  93. 294 TLR 9 INHIBITION: A NOVEL TARGET OF THERAPY FOR PRIMARY LIVER CANCER

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  94. 248 EVIDENCE REFUTING THE TROJAN-HORSE HYPOTHESIS OF BRAIN SWELLING IN ACUTE LIVER FAILURE: L-TYPE GLUTAMINASE IS EXCLUSIVELY NEURONAL

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  95. 250 EVALUATION OF HAEMOSTASIS IN ACUTE LIVER FAILURE: A COMPREHENSIVE STUDY USING TRADITIONAL PLASMATIC TESTS AND WHOLE BLOOD THROMBOELASTOGRAPHY

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan, Dr Alex Gatt

  96. 581 GUT DECONTAMINATION USING NANOPOROUS CARBONS REDUCES PORTAL PRESSURE AND PREVENTS LIVER FAILURE IN BILE-DUCT LIGATED CIRRHOTIC ANIMALS BY REDUCING KUPFFER CELL ACTIVATION

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  97. 748 BLOOD LIPIDOMIC PROFILING OF HEPATOCELLULAR CARCINOMA IN HUMAN AND ANIMAL STUDIES IDENTIFIES LYSOPHOSPHATIDYLCHOLINE (24, 0, 0) AS A DISCRIMINATORY BIOMARKER

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  98. 680 URINARY TLR4: A NOVEL BIOMARKER TO IDENTIFY PATIENTS WITH ACUTE KIDNEY INJURY IN PATIENTS WITH ACUTE ON CHRONIC LIVER FAILURE

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  99. 243 A REPRODUCIBLE, CLINICALLY-RELEVANT, INTENSIVELY-MANAGED, PIG MODEL OF ACUTE LIVER FAILURE FOR TESTING OF THERAPIES AIMED TO PROLONG SURVIVAL

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  100. 238 EXTRACORPOREAL LIVER SUPPORT USING UCL-ARSENEL REDUCES INFLAMMATION, IMPROVES HAEMODYNAMIC FUNCTION AND INCREASE SURVIVAL TIME IN A PORCINE PARACETAMOL-INDUCED ACUTE LIVER FAILURE MODEL

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  101. 293 SELECTIVE GUT DECOMTAMINATION REDUCES HEPATIC EXPRESSION OF TOLL-LIKE RECEPTOR (TLR) 4 AND DEVELOPMENT OF CIRRHOSIS BUT DOES NOT PREVENT DEVELOPMENT OF HEPATOCELLULAR CARCINOMA (HCC)

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  102. 586 RENAL NKCC2 TRANSPORTER TRIGGERS ENHANCED URINARY AMMONIA EXCRETION DURING INDUCED HYPERAMMONEMIA: A NOVEL TARGET OF THERAPY FOR HEPATIC ENCEPHALOPATHY?

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  103. 91 TOLL LIKE RECEPTOR 4 ANTAGONIST PREVENTS ACETAMINOPHEN INDUCED ACUTE LIVER FAILURE IN MICE: A NOVEL THERAPEUTIC STRATEGY

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  104. MODULATION OF TOLL-LIKE RECEPTOR GENES WITH SELECTIVE GUT DECONTAMINATION IN CIRRHOTIC ANIMALS PREVENTS THE DEVELOPMENT OF ACUTE-ON CHRONIC LIVER FAILURE (ACLF)

    Article • Journal of Hepatology, April 2012, Elsevier

    Professor Rajiv Jalan

  105. Systems Biology of the Liver

    Article • March 2012, Wiley

    Ian David Bogle, Professor Rajiv Jalan

  106. Dogs with congenital porto-systemic shunting (cPSS) and hepatic encephalopathy have higher serum concentrations of C-reactive protein than asymptomatic dogs with cPSS

    Article • Metabolic Brain Disease, February 2012, Springer Science + Business Media

    Professor Rajiv Jalan

  107. The Rise of Glutaminase in End-Stage Liver Diseases

    Article • February 2012, IntechOpen

    Professor Rajiv Jalan

  108. ‘Out-patient’ albumin dialysis for cholestatic patients with intractable pruritus

    Article • Alimentary Pharmacology & Therapeutics, January 2012, Wiley

    Professor Rajiv Jalan

  109. Extracorporeal Liver Support

    Article • Blood Purification, January 2012, Karger Publishers

    Professor Rajiv Jalan

  110. Ornithine Phenylacetate: A Novel Strategy for the Treatment of Hepatic Encephalopathy

    Article • January 2012, Springer Science + Business Media

    Professor Rajiv Jalan

  111. Role of predisposition, injury, response and organ failure in the prognosis of patients with acute-on-chronic liver failure: a prospective cohort study

    Article • Critical Care, January 2012, Springer Science + Business Media

    Professor Rajiv Jalan

  112. Reduction in hyperammonaemia by ornithine phenylacetate prevents lipopolysaccharide-induced brain edema and coma in cirrhotic rats

    Article • Liver International, December 2011, Wiley

    Professor Rajiv Jalan

  113. The role of liver biopsy in the diagnosis and prognosis of patients with acute deterioration of alcoholic cirrhosis

    Article • Journal of Hepatology, November 2011, Elsevier

    Professor Rajiv Jalan

  114. Intensive care of the patient with cirrhosis

    Article • Hepatology, October 2011, Wiley

    Professor Rajiv Jalan

  115. P17 TIPS outcomes for Budd-Chiari: a single tertiary centre experience

    Article • Gut, September 2011, BMJ

    Professor Rajiv Jalan

  116. OP09 TIPS outcomes for refractory ascites: a single centre experience

    Article • Gut, September 2011, BMJ

    Professor Rajiv Jalan

  117. Acute-on-chronic liver failure: from concept to a new syndrome

    Article • Current Opinion in Critical Care, April 2011, Wolters Kluwer Health

    Professor Rajiv Jalan

  118. 611 PROGRESSION OF HEMODYNAMIC CHANGES IN LIVER CIRRHOSIS. A MATHEMATICAL APPROACH

    Article • Journal of Hepatology, March 2011, Elsevier

    Professor Rajiv Jalan

  119. 620 IMMUNOHISTOCHEMICAL CHARACTERIZATION OF ASTROGLIAL IMMUNE RESPONSES IN CIRRHOTIC RATS

    Article • Journal of Hepatology, March 2011, Elsevier

    Professor Rajiv Jalan

  120. Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis

    Article • Gut, February 2011, BMJ

    Professor Rajiv Jalan

  121. Stumbling into encephalopathy: chest trauma in a patient with alcoholic cirrhosis

    Article • British Journal of Hospital Medicine, February 2011, Mark Allen Group

    Professor Rajiv Jalan

  122. Interorgan ammonia metabolism in liver failure: the basis of current and future therapies

    Article • Liver International, January 2011, Wiley

    Professor Rajiv Jalan

  123. Management of Hepatic Encephalopathy

    Article • International Journal of Hepatology, January 2011, Hindawi Publishing Corporation

    Professor Rajiv Jalan

  124. Improving Survival in Patients with Decompensated Cirrhosis

    Article • International Journal of Hepatology, January 2011, Hindawi Publishing Corporation

    Professor Rajiv Jalan

  125. Autotaxin spiegelt das Therapieansprechen bei cholestatischem Pruritus wider

    Article • Seminars in Musculoskeletal Radiology, January 2011, Thieme Publishing Group

    Professor Rajiv Jalan

  126. SIRS, Bacterial Infections, and Alterations of the Immune System

    Article • October 2010, Springer Science + Business Media

    Professor Rajiv Jalan

  127. Acute-on-chronic liver failure: an early biopsy is essential?

    Article • Gut, October 2010, BMJ

    Professor Rajiv Jalan

  128. Rifaximin in hepatic encephalopathy: More than just a non-absorbable antibiotic?

    Article • Journal of Hepatology, September 2010, Elsevier

    Professor Rajiv Jalan

  129. Role of aquaporin-4 in the development of brain oedema in liver failure

    Article • Journal of Hepatology, July 2010, Elsevier

    Professor Rajiv Jalan

  130. Blood-brain barrier in liver failure: are cracks appearing in the wall?

    Article • Liver International, June 2010, Wiley

    Professor Rajiv Jalan

  131. Short chain fatty acids exchange: Is the cirrhotic, dysfunctional liver still able to clear them?

    Article • Clinical Nutrition, June 2010, Elsevier

    Professor Rajiv Jalan

  132. Intrinsic renal disease in cirrhosis:adding insult to injury

    Article • Liver International, May 2010, Wiley

    Professor Rajiv Jalan

  133. Alcohol takes the toll on immune function

    Article • Liver International, April 2010, Wiley

    Professor Rajiv Jalan

  134. 1184 EXTRACORPOREAL LIVER SUPPORT WITH THE MOLECULAR ADSORBENT RECIRCULATING SYSTEM (MARS) IN PATIENTS WITH ACUTE-ON-CHRONIC LIVER FAILURE (AOCLF). THE RELIEF TRIAL

    Article • Journal of Hepatology, April 2010, Elsevier

    Professor Rajiv Jalan

  135. 523 HEMODYNAMIC EFFECTS OF TEZOSENTAN, A DUAL ENDOTHELIN RECEPTOR ANTAGONIST, IN PATIENTS WITH CIRRHOSIS

    Article • Journal of Hepatology, April 2010, Elsevier

    Professor Rajiv Jalan

  136. 537 RESTORATION OF THE L-ARGININE:ADMA RATIO BY L-ARGININE TREATMENT IN BILE DUCT LIGATED RATS RESULTS IN SIGNIFICANT LOWERING OF PORTAL PRESSURE

    Article • Journal of Hepatology, April 2010, Elsevier

    Professor Rajiv Jalan

  137. P.157 “OUT-PATIENT” ALBUMIN DIALYSIS FOR INTRACTABLE ITCH IN CHRONIC CHOLESTATIC LIVER DISEASE IS AN ALTERNATIVE TO LIVER TRANSPLANTATION

    Article • Digestive and Liver Disease, March 2010, Elsevier

    Professor Rajiv Jalan

  138. F.N.18 NEUTROPHIL PHAGOCYTIC DYSFUNCTION IN STABLE CIRRHOSIS IS INDEPENDENT OF BACTERIAL DNA AND ASSOCIATED WITH INCREASED EXPRESSION OF TLR-4

    Article • Digestive and Liver Disease, February 2010, Elsevier

    Professor Rajiv Jalan

  139. Albumin: Not Just a Plasma Expander

    Article • January 2010, Karger Publishers

    Professor Rajiv Jalan

  140. Infection and inflammation in liver failure: Two sides of the same coin

    Article • Journal of Hepatology, September 2009, Elsevier

    Professor Rajiv Jalan

  141. Treatment of Hyperammonemia in Liver Failure: A Tale of Two Enzymes

    Article • Gastroenterology, June 2009, Elsevier

    Professor Rajiv Jalan

  142. Review article: hyperammonaemic and catabolic consequences of upper gastrointestinal bleeding in cirrhosis

    Article • Alimentary Pharmacology & Therapeutics, April 2009, Wiley

    Professor Rajiv Jalan

  143. 494 THE BIOMARKER ‘DASIMAR’ (DIMETHYLARGININE SCORE AND ISCHAEMIA MODIFIED ALBUMIN RATIO) IS AN EARLY PREDICTOR OF MORTALITY IN PATIENTS WITH ACUTE LIVER FAILURE

    Article • Journal of Hepatology, April 2009, Elsevier

    Professor Rajiv Jalan

  144. 734 TREATMENT WITH INFLIXIMAB INCREASES E-NOS ACTIVITY IN CIRRHOSIS THROUGH MODULATION OF THE DDAH-ADMA PATHWAY

    Article • Journal of Hepatology, April 2009, Elsevier

    Professor Rajiv Jalan

  145. 771 EVIDENCE OF SEVERE NEUTROPHIL DYSFUNCTION IN STABLE CIRRHOSIS USING A NOVEL IN VIVO MODEL OF INFLAMMATION

    Article • Journal of Hepatology, April 2009, Elsevier

    Professor Rajiv Jalan

  146. 773 REDUCTION IN AMMONIA WITH L-ORNITHINE, PHENYLACETATE (OP) BUT NOT ANTI-TNF PREVENTS LPS INDUCED BRAIN EDEMA IN BILE-DUCT LIGATED CIRRHOTIC RATS

    Article • Journal of Hepatology, April 2009, Elsevier

    Professor Rajiv Jalan

  147. 154 THE CONTRIBUTIONS OF DE NOVO ARGININE GENERATION AND ARGINASE ACTIVITY TO WHOLE BODY ARGININE METABOLISM IN ACUTE LIVER FAILURE

    Article • Journal of Hepatology, April 2009, Elsevier

    Professor Rajiv Jalan

  148. Demonstration of dysfunction in neutrophil phagocytosis in stable cirrhosis using a novel in vivo model of inflammation

    Article • Digestive and Liver Disease, March 2009, Elsevier

    Professor Rajiv Jalan

  149. L-ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure

    Article • Hepatology, February 2009, Wiley

    Professor Rajiv Jalan

  150. Alterations in the functional capacity of albumin in patients with decompensated cirrhosis is associated with increased mortality

    Article • Hepatology, February 2009, Wiley

    Professor Rajiv Jalan

  151. L-ornithine and phenylacetate synergistically produce sustained reduction in ammonia and brain water in cirrhotic rats

    Article • Hepatology, February 2009, Wiley

    Professor Rajiv Jalan

  152. Role of artificial liver support in hepatic encephalopathy

    Article • Metabolic Brain Disease, December 2008, Springer Science + Business Media

    Professor Rajiv Jalan

  153. Interorgan ammonia trafficking in liver disease

    Article • Metabolic Brain Disease, December 2008, Springer Science + Business Media

    Professor Rajiv Jalan

  154. Probiotics for patients with liver cirrhosis: Reply

    Article • Journal of Hepatology, December 2008, Elsevier

    Professor Rajiv Jalan

  155. Role of Toll-like receptors 2, 4, and 9 in mediating neutrophil dysfunction in alcoholic hepatitis

    Article • AJP Gastrointestinal and Liver Physiology, November 2008, American Physiological Society

    Professor Rajiv Jalan

  156. Protein synthesis is severely diminished following a simulated upper GI bleed in patients with cirrhosis

    Article • Journal of Hepatology, November 2008, Elsevier

    Professor Rajiv Jalan

  157. High prevalence of abnormal alanine and aspartate aminotransferases in a “worried-well” population in the United Kingdom: Rationale for a liver screening program?

    Article • Hepatology, August 2008, Wiley

    Professor Rajiv Jalan

  158. Ammonia impairs neutrophil phagocytic function in liver disease

    Article • Hepatology, June 2008, Wiley

    Professor Rajiv Jalan

  159. Liver failure after partial hepatic resection: definition, pathophysiology, risk factors and treatment

    Article • Liver International, June 2008, Wiley

    Professor Rajiv Jalan

  160. Effect of probiotic treatment on deranged neutrophil function and cytokine responses in patients with compensated alcoholic cirrhosis

    Article • Journal of Hepatology, June 2008, Elsevier

    Professor Rajiv Jalan

  161. Artificial Liver Support Systems in the Management of Complications of Cirrhosis

    Article • Seminars in Liver Disease, February 2008, Thieme Publishing Group

    Professor Rajiv Jalan

  162. Relationship Between Activation of the Sympathetic Nervous System and Renal Blood Flow Autoregulation in Cirrhosis

    Article • Gastroenterology, January 2008, Elsevier

    Professor Rajiv Jalan

  163. Towards goal-directed therapy of hepatorenal syndrome: we have the tools but we need the trials

    Article • Critical Care, January 2008, Springer Science + Business Media

    Professor Rajiv Jalan

  164. 33 INCREASED NEUTROPHIL TOLL-LIKE-RECEPTOR 2, 4 AND 9 EXPRESSION IN ALCOHOLIC HEPATITIS IS A RESULT OF ITS ACTIVATION RATHER THAN ITS CAUSE

    Article • Journal of Hepatology, January 2008, Elsevier

    Professor Rajiv Jalan

  165. 953 EARLY LIVER BIOPSY IS CRUCIAL FOR ACCURATE DIAGNOSIS OF ALCOHOLIC HEPATITIS AND PROVIDES INDEPENDENT PROGNOSTIC INFORMATION IN PATIENTS WITH DECOMPENSATED ALCOHOLIC LIVER DISEASE

    Article • Journal of Hepatology, January 2008, Elsevier

    Professor Rajiv Jalan

  166. Response to letter by R. Mookerjee and R. Jalan

    Article • European Journal of Clinical Investigation, December 2007, Wiley

    Professor Rajiv Jalan

  167. ADMA correlates with portal pressure in patients with compensated cirrhosis by Vizzutti et al. Eur J Clin Invest 2007; 37: 509-15

    Article • European Journal of Clinical Investigation, December 2007, Wiley

    Professor Rajiv Jalan

  168. Endotoxin measures in patients’ sample: How valid are the results?

    Article • Journal of Hepatology, November 2007, Elsevier

    Professor Rajiv Jalan

  169. Brain cytokine flux in acute liver failure and its relationship with intracranial hypertension

    Article • Metabolic Brain Disease, September 2007, Springer Science + Business Media

    Professor Rajiv Jalan

  170. Lack of renal improvement with nonselective endothelin antagonism with tezosentan in type 2 hepatorenal syndrome

    Article • Hepatology, September 2007, Wiley

    Dr Jasper Dingemanse, Professor Rajiv Jalan

  171. The treatment of hepatic encephalopathy

    Article • Metabolic Brain Disease, September 2007, Springer Science + Business Media

    Professor Rajiv Jalan

  172. Malnutrition and diabetes mellitus are related to hepatic encephalopathy in patients with liver cirrhosis

    Article • Liver International, August 2007, Wiley

    Professor Rajiv Jalan

  173. Association of reduced extracellular brain ammonia, lactate, and intracranial pressure in pigs with acute liver failure

    Article • Hepatology, August 2007, Wiley

    Professor Rajiv Jalan

  174. Protocols and Mechanisms for Remote Ischemic Preconditioning: A Novel Method for Reducing Ischemia Reperfusion Injury

    Article • Transplantation, August 2007, Wolters Kluwer Health

    Professor Rajiv Jalan

  175. Induction of cerebral hyperemia by ammonia plus endotoxin: Does hyperammonemia unlock the blood–brain barrier?

    Article • Journal of Hepatology, August 2007, Elsevier

    Professor Rajiv Jalan

  176. Increased Gene and Protein Expression of the Novel eNOS Regulatory Protein NOSTRIN and a Variant in Alcoholic Hepatitis

    Article • Gastroenterology, June 2007, Elsevier

    Professor Rajiv Jalan

  177. Acute liver failure: liver support therapies

    Article • Current Opinion in Critical Care, April 2007, Wolters Kluwer Health

    Professor Rajiv Jalan

  178. [250] THE EFFECTS OF TEZOSENTAN, AN ENDOTHELIN RECEPTOR ANTAGONIST, ON RENAL FUNCTION IN PATIENTS WITH CIRRHOSIS COMPLICATED BY ASCITES AND HEPATORENAL SYNDROME

    Article • Journal of Hepatology, April 2007, Elsevier

    Professor Rajiv Jalan

  179. [232] ALBUMIN INFUSION FOR SEVERE HYPONATREMIA IN PATIENTS WITH REFRACTORY ASCITES: A RANDOMIZED CLINICAL TRIAL

    Article • Journal of Hepatology, April 2007, Elsevier

    Professor Rajiv Jalan

  180. [212] BRAIN SWELLING AND COMA IN CIRRHOTIC RATS ADMINISTERED ENDOTOXIN IS ASSOCIATED WITH INCREASED PROTEIN NITROSATION

    Article • Journal of Hepatology, April 2007, Elsevier

    Professor Rajiv Jalan

  181. [213] LIPOPOLYSACCHARIDE EXACERBATES BRAIN EDEMA AND PRODUCES COMA IN CIRRHOTIC RATS THROUGH A CYTOTOXIC MECHANISM: AN ELECTRON-MICROSCOPIC STUDY

    Article • Journal of Hepatology, April 2007, Elsevier

    Professor Rajiv Jalan

  182. quantitative tests of liver function

    Article • Alimentary Pharmacology & Therapeutics, March 2007, Wiley

    Professor Rajiv Jalan

  183. Isoleucine infusion during “simulated” upper gastrointestinal bleeding improves liver and muscle protein synthesis in cirrhotic patients

    Article • Hepatology, March 2007, Wiley

    Professor Rajiv Jalan

  184. Role of ammonia and inflammation in minimal hepatic encephalopathy

    Article • Metabolic Brain Disease, January 2007, Springer Science + Business Media

    Professor Rajiv Jalan

  185. Ammonia and inflammation in the pathogenesis of hepatic encephalopathy: Pandora's box?

    Article • Hepatology, January 2007, Wiley

    Professor Rajiv Jalan

  186. The puzzle of endothelial nitric oxide synthase dysfunction in portal hypertension: The missing piece?

    Article • Hepatology, January 2007, Wiley

    Professor Rajiv Jalan

  187. Management of hepatic encephalopathy in patients with cirrhosis

    Article • Best Practice & Research Clinical Gastroenterology, January 2007, Elsevier

    Professor Rajiv Jalan

  188. Endotoxemia during liver transplantation

    Article • Liver Transplantation, January 2007, Wiley

    Professor Rajiv Jalan

  189. Neutrophil dysfunction in alcoholic hepatitis superimposed on cirrhosis is reversible and predicts the outcome

    Article • Hepatology, January 2007, Wiley

    Professor Rajiv Jalan

  190. l-Ornithine phenylacetate (OP): A novel treatment for hyperammonemia and hepatic encephalopathy

    Article • Medical Hypotheses, January 2007, Elsevier

    Professor Rajiv Jalan

  191. Endotoxemia produces coma and brain swelling in bile duct ligated rats

    Article • Hepatology, January 2007, Wiley

    Professor Rajiv Jalan

  192. Inflammation is an important determinant of levels of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) in acute liver failure

    Article • Liver Transplantation, January 2007, Wiley

    Professor Rajiv Jalan

  193. Paracetamol: are therapeutic doses entirely safe?

    Article • The Lancet, December 2006, Elsevier

    Professor Rajiv Jalan

  194. Transjugular intrahepatic portosystemic stent-shunt in the management of gastric and ectopic varices

    Article • European Journal of Gastroenterology & Hepatology, November 2006, Wolters Kluwer Health

    Professor Rajiv Jalan

  195. Acute Liver Failure: a Review

    Article • Clinics in Liver Disease, May 2006, Elsevier

    Professor Rajiv Jalan

  196. 189 Hepatic inflammation increases portal pressure through inhibition of eNOS activity — Potential mechanisms

    Article • Journal of Hepatology, April 2006, Elsevier

    Professor Rajiv Jalan

  197. Arginine, citrulline, and nitric oxide metabolism in patients with liver failure and the effect of intervention with hypothermia and transplantation

    Article • European Journal of Gastroenterology & Hepatology, January 2006, Wolters Kluwer Health

    Professor Rajiv Jalan

  198. Remote ischaemic preconditioning of the hind limb reduces experimental liver warm ischaemia–reperfusion injury

    Article • British Journal of Surgery, January 2006, Wiley

    Professor Rajiv Jalan

  199. Systemic and regional haemodynamics in pigs with acute liver failure and the effect of albumin dialysis

    Article • Scandinavian Journal of Gastroenterology, January 2006, Taylor & Francis

    Professor Rajiv Jalan

  200. The pathophysiologic basis of hepatic encephalopathy: central role for ammonia and inflammation

    Article • Cellular and Molecular Life Sciences, September 2005, Springer Science + Business Media

    Professor Rajiv Jalan

  201. Ammonia and Hepatic Encephalopathy: The More Things Change, the More They Remain the Same

    Article • Metabolic Brain Disease, September 2005, Springer Science + Business Media

    Professor Rajiv Jalan

  202. Pathophysiological basis of therapy of raised intracranial pressure in acute liver failure

    Article • Neurochemistry International, July 2005, Elsevier

    Professor Rajiv Jalan

  203. Albumin dialysis reduces portal pressure acutely in patients with severe alcoholic hepatitis

    Article • Journal of Hepatology, July 2005, Elsevier

    Professor Rajiv Jalan

  204. Reply

    Article • Gastroenterology, April 2005, Elsevier

    Professor Rajiv Jalan

  205. Treatment of hepatic encephalopathy

    Article • The Lancet, April 2005, Elsevier

    Professor Rajiv Jalan

  206. Acute liver failure: current management and future prospects

    Article • Journal of Hepatology, April 2005, Elsevier

    Professor Rajiv Jalan

  207. Emerging Indications for Albumin Dialysis

    Article • The American Journal of Gastroenterology, February 2005, Wolters Kluwer Health

    Professor Rajiv Jalan

  208. Dispelling myths in the treatment of hepatic encephalopathy

    Article • The Lancet, January 2005, Elsevier

    Professor Rajiv Jalan

  209. Letter to the Editors

    Article • Liver Transplantation, January 2005, Wiley

    Professor Rajiv Jalan

  210. Gc-globulin to predict outcome in acute liver failure: A panacea?

    Article • Liver Transplantation, January 2005, Wiley

    Professor Rajiv Jalan

  211. Transjugular Intrahepatic Portosystemic Stent-Shunt

    Article • January 2005, Springer Science + Business Media

    Professor Rajiv Jalan

  212. Dispelling myths in the treatment of hepatic encephalopathy

    Article • The Lancet, January 2005, Elsevier

    Professor Rajiv Jalan

  213. `Nipped in the Budd'

    Article • European Journal of Gastroenterology & Hepatology, January 2005, Wolters Kluwer Health

    Professor Rajiv Jalan

  214. Hypothermia in Acute Liver Failure

    Article • Metabolic Brain Disease, December 2004, Springer Science + Business Media

    Professor Rajiv Jalan

  215. A model to study total hepatic ischemia–reperfusion injury

    Article • Transplantation Proceedings, November 2004, Elsevier

    Professor Rajiv Jalan

  216. Moderate hypothermia in patients with acute liver failure and uncontrolled intracranial hypertension

    Article • Gastroenterology, November 2004, Elsevier

    Professor Rajiv Jalan

  217. Pathogenesis of intracranial hypertension in acute liver failure: inflammation, ammonia and cerebral blood flow

    Article • Journal of Hepatology, October 2004, Elsevier

    Professor Rajiv Jalan

  218. PROSPECTS FOR EXTRACORPOREAL LIVER SUPPORT

    Article • Gut, June 2004, BMJ

    Professor Rajiv Jalan

  219. Extracorporeal Albumin Dialysis for Intoxication from Protein-Bound Agents

    Article • Critical Care Medicine, June 2004, Wolters Kluwer Health

    Professor Rajiv Jalan

  220. Reversal of diuretic-induced hepatic encephalopathy with infusion of albumin but not colloid

    Article • Clinical Science, May 2004, Portland Press Ltd.

    Professor Rajiv Jalan

  221. Albumin dialysis: a new therapeutic strategy for intoxication from protein-bound drugs

    Article • Intensive Care Medicine, March 2004, Springer Science + Business Media

    Professor Rajiv Jalan

  222. Systemic inflammatory response exacerbates the neuropsychological effects of induced hyperammonemia in cirrhosis

    Article • Journal of Hepatology, February 2004, Elsevier

    Professor Rajiv Jalan

  223. Should a biopsy precede liver resection or transplantation for presumed hepatocellular carcinoma when the alfa fetoprotein is normal?

    Article • Transplantation, February 2004, Wolters Kluwer Health

    Professor Rajiv Jalan

  224. Infliximab and alcoholic hepatitis

    Article • Hepatology, January 2004, Wiley

    Professor Rajiv Jalan

  225. Is minimal hepatic encephalopathy completely reversible following liver transplantation?

    Article • Liver Transplantation, January 2004, Wiley

    Professor Rajiv Jalan

  226. Binding of bilirubin and bromosulphthalein to albumin: Implications for understanding the pathophysiology of liver failure and its management

    Article • Liver Transplantation, January 2004, Wiley

    Professor Rajiv Jalan

  227. The role of the Molecular Adsorbents Recirculating System (MARS) in the management of liver failure

    Article • Perfusion, January 2004, SAGE Publications

    Professor Rajiv Jalan

  228. Worsening of cerebral hyperemia by the administration of terlipressin in acute liver failure with severe encephalopathy

    Article • Hepatology, January 2004, Wiley

    Professor Rajiv Jalan

  229. Contractile response of femoral arteries in pigs with acute liver failure

    Article • Scandinavian Journal of Gastroenterology, January 2004, Taylor & Francis

    Professor Rajiv Jalan

  230. Pathophysiological effects of albumin dialysis in acute-on-chronic liver failure: A randomized controlled study

    Article • Liver Transplantation, January 2004, Wiley

    Professor Rajiv Jalan

  231. 193 Aseptic inflammation independent of its source is important in the development of advanced grades of encephalopathy in alcoholic cirrhosis

    Article • Journal of Hepatology, January 2004, Elsevier

    Professor Rajiv Jalan

  232. Urotensin II: better than somatostatin for portal hypertension?

    Article • Hepatology, December 2003, Wiley

    Professor Rajiv Jalan

  233. Reply

    Article • Hepatology, September 2003, Wiley

    Professor Rajiv Jalan

  234. Liver failure: basis of benefit of therapy with the molecular adsorbents recirculating system

    Article • The International Journal of Biochemistry & Cell Biology, September 2003, Elsevier

    Professor Rajiv Jalan

  235. The molecular pathogenesis of hepatic encephalopathy

    Article • The International Journal of Biochemistry & Cell Biology, August 2003, Elsevier

    Professor Rajiv Jalan

  236. Enhanced renal ammonia excretion following volume expansion in patients with well compensated cirrhosis of the liver

    Article • Gut, July 2003, BMJ

    Professor Rajiv Jalan

  237. The kidney plays a major role in the hyperammonemia seen after simulated or actual GI bleeding in patients with cirrhosis

    Article • European Journal of Gastroenterology & Hepatology, July 2003, Wolters Kluwer Health

    Professor Rajiv Jalan

  238. Correspondence

    Article • Hepatology, June 2003, Wiley

    Professor Rajiv Jalan

  239. Moderate hypothermia prevents cerebral hyperemia and increase in intracranial pressure in patients undergoing liver transplantation for acute liver failure

    Article • Transplantation, June 2003, Wolters Kluwer Health

    Professor Rajiv Jalan

  240. Reversal of severe cholestasis caused by chronic graft-versus-host disease with the MARS liver-support device

    Article • Transplantation, May 2003, Wolters Kluwer Health

    Professor Rajiv Jalan

  241. Decompensation of chronic stable alcoholic liver disease by severe exfoliative dermatitis

    Article • European Journal of Gastroenterology & Hepatology, April 2003, Wolters Kluwer Health

    Professor Rajiv Jalan

  242. Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis

    Article • Journal of Hepatology, April 2003, Elsevier

    Professor Rajiv Jalan

  243. Treatment of Phenytoin Toxicity by the Molecular Adsorbents Recirculating System (MARS)

    Article • Epilepsia, February 2003, Wiley

    Professor Rajiv Jalan

  244. Extracorporeal liver support with molecular adsorbents recirculating system in patients with severe acute alcoholic hepatitis

    Article • Journal of Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  245. 167 Pre-primed neutrophil oxidative burst is independent of clinical severity and outcome in patients with severe alcoholic liver disease

    Article • Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  246. 169 Kinetics of binding of non-dialysable substances to albumin: relevance in liver disease

    Article • Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  247. 173 Pathophysiological basis of extracorporeal albumin dialysis with MARS in acute-on-chronic liver failure due to alcohol

    Article • Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  248. 531 Hepatic inflammation is an important modulator of the circulatory disturbances in cirrhosis

    Article • Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  249. 536 Evidence for altered renal blood flow autoregulation in cirrhosis

    Article • Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  250. 652 Remote ischaemic preconditioning of the hind limb improves systemic haemodynamics and reduces reperfusion injury to the liver and lungs

    Article • Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  251. 787 Worsening of cerebral hyperemia in acute liver failure with severe hepatic encephalopathy following terlipressin?

    Article • Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  252. 801 Brain production of pro-inflammatory cytokines in patients with acute liver failure and uncontrolled intracranial hypertension: evidence of disrupted blood brain barrier?

    Article • Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  253. Molecular Adsorbents Recirculating System (MARS) for acute decompensation of chronic liver disease: an early clinical experience

    Article • January 2003, Springer Science + Business Media

    Professor Rajiv Jalan

  254. Hypothermia for the management of intracranial hypertension in acute liver failure

    Article • January 2003, Springer Science + Business Media

    Professor Rajiv Jalan

  255. Nitric oxide mediates the reduced vasoconstrictor response to angiotensin II in patients with preascitic cirrhosis

    Article • Journal of Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  256. 809 Improvement in cerebral lactate, glutamate and energy metabolism with albumin dialysis in a large animal model of acute liver failure: a microdialysis study

    Article • Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  257. 1083 MARS treatment improves renal function independent of systemic haemodynamics in acute liver failure: a randomized controlled study in a pig model

    Article • Hepatology, January 2003, Elsevier

    Professor Rajiv Jalan

  258. Terlipressin-induced vasoconstriction reversed with N-acetylcysteine: A case for combined use in hepatorenal syndrome?

    Article • Gastroenterology, December 2002, Elsevier

    Professor Rajiv Jalan

  259. Review article: the Molecular Adsorbents Recirculating System (MARS) in liver failure

    Article • Alimentary Pharmacology & Therapeutics, November 2002, Wiley

    Professor Rajiv Jalan

  260. Albumin dialysis and Molecular Adsorbents Recirculating System (MARS) for acute Wilson's disease

    Article • Liver Transplantation, October 2002, Wiley

    Professor Rajiv Jalan

  261. Liver derived pro-inflammatory cytokines may be important in producing intracranial hypertension in acute liver failure

    Article • Journal of Hepatology, October 2002, Elsevier

    Professor Rajiv Jalan

  262. Primary prophylaxis of variceal hemorrhage: A randomized controlled trial comparing band ligation, propranolol, and isosorbide mononitrate

    Article • Gastroenterology, September 2002, Elsevier

    Professor Rajiv Jalan

  263. Interorgan ammonia metabolism in liver failure

    Article • Neurochemistry International, August 2002, Elsevier

    Professor Rajiv Jalan

  264. Impact of transjugular intrahepatic portosystemic stent-shunt for secondary prophylaxis of oesophageal variceal haemorrhage: a single-centre study over an 11-year period

    Article • European Journal of Gastroenterology & Hepatology, June 2002, Wolters Kluwer Health

    Professor Rajiv Jalan

  265. Is “Gilbert's” the culprit in indinavir-induced hyperbilirubinemia?

    Article • Hepatology, May 2002, Wiley

    Professor Rajiv Jalan

  266. The pathophysiological basis of acute-on-chronic liver failure

    Article • April 2002, Wiley

    Professor Rajiv Jalan

  267. Novel spin trap findings demonstrating severe oxidative stress in alcoholic hepatitis

    Article • Journal of Hepatology, April 2002, Elsevier

    Professor Rajiv Jalan

  268. Increased cerebral and peripheral vasodilation, and whole body nitricoxide (NO) production after insertion of a transjugular intrahepatic portosystemic stent-shunt (TIPSS) in patients with cirrhosis

    Article • Journal of Hepatology, April 2002, Elsevier

    Professor Rajiv Jalan

  269. BIO-ARTIFICIAL LIVER SUPPORT FOR ACUTE LIVER FAILURE: SHOULD WE BE USING IT TO TREAT PATIENTS?

    Article • Transplantation, January 2002, Wolters Kluwer Health

    Professor Rajiv Jalan

  270. Acute-on-Chronic Liver Failure: Pathophysiological Basis of Therapeutic Options

    Article • Blood Purification, January 2002, Karger Publishers

    Professor Rajiv Jalan

  271. Delayed opioid withdrawal-like reaction in primary biliary cirrhosis following naloxone therapy

    Article • Gastroenterology, September 2001, Elsevier

    Professor Rajiv Jalan

  272. Hypothermia for the management of intracranial hypertension in acute liver failure

    Article • Current Opinion in Critical Care, August 2001, Wolters Kluwer Health

    Professor Rajiv Jalan

  273. Editorial: Improvement in cerebral perfusion after MARS therapy: Further clues about the pathogenesis of hepatic encephalopathy?

    Article • Liver Transplantation, August 2001, Wiley

    Professor Rajiv Jalan

  274. Mars in decompensated Alcoholic Liver Disease with Multi-Organ Failure

    Article • Seminars in Musculoskeletal Radiology, July 2001, Thieme Publishing Group

    Professor Rajiv Jalan

  275. Restoration of cerebral blood flow autoregulation and reactivity to carbon dioxide in acute liver failure by moderate hypothermia

    Article • Hepatology, July 2001, Wiley

    Professor Rajiv Jalan

  276. The inflammatory basis of intracranial hypertension in acute liver failure

    Article • Journal of Hepatology, June 2001, Elsevier

    Professor Rajiv Jalan

  277. Primary prophylaxis of variceal bleeding in cirrhosis

    Article • April 2001, Wolters Kluwer Health

    Professor Rajiv Jalan

  278. Altered peripheral vascular responses to vasoactive mediators in patients with pre-ascitic cirrhosis: role of nitric oxide

    Article • Journal of Hepatology, April 2001, Elsevier

    Professor Rajiv Jalan

  279. Study of regional neutrophil chemotaxis in chronic liver diseases (CLD)

    Article • Journal of Hepatology, April 2001, Elsevier

    Professor Rajiv Jalan

  280. Enhanced renal ammonia excretion following volume expansion is mediated through the renin-angiotensin system

    Article • Journal of Hepatology, April 2001, Elsevier

    Professor Rajiv Jalan

  281. Randomised controlled trial of transjugular intra-hepatic portosystemic stent-shunt (TIPSS) versus tipss and variceal band ligation (VBL) in the prevention of variceal rebleeding

    Article • Journal of Hepatology, April 2001, Elsevier

    Professor Rajiv Jalan

  282. Acute changes in cerebral blood flow and metabolism during portasystemic shunting

    Article • Liver Transplantation, March 2001, Wiley

    Professor Rajiv Jalan

  283. Vascular hyporesponsiveness in cirrhosis - many facets of a common problem!

    Article • European Journal of Clinical Investigation, February 2001, Wiley

    Professor Rajiv Jalan

  284. MARS: A new treatment for hepatorenal failure

    Article • Gastroenterology, December 2000, Elsevier

    Professor Rajiv Jalan

  285. Losartan and renal sodium handling Reply

    Article • Gut, October 2000, BMJ

    Professor Rajiv Jalan

  286. UK guidelines on the management of variceal haemorrhage in cirrhotic patients

    Article • Gut, June 2000, BMJ

    Professor Rajiv Jalan

  287. TIPSS 10 years on

    Article • Gut, April 2000, BMJ

    Professor Rajiv Jalan

  288. Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis

    Article • Gut, April 2000, BMJ

    Professor Rajiv Jalan

  289. Sodium handling in patients with well compensated cirrhosis is dependent on the severity of liver disease and portal pressure

    Article • Gut, April 2000, BMJ

    Professor Rajiv Jalan

  290. Hypothermia for fulminant hepatic failure: A cool approach to a burning problem

    Article • Liver Transplantation, March 2000, Wiley

    Professor Rajiv Jalan

  291. Role of angiotensin II in regulation of basal and sympathetically stimulated vascular tone in early and advanced cirrhosis

    Article • Gastroenterology, March 2000, Elsevier

    Professor Rajiv Jalan

  292. Double blind randomised study of effect of simulated bleeding onneutrophil chemotaxis in patients with cirrhosis

    Article • Journal of Hepatology, January 2000, Elsevier

    Professor Rajiv Jalan

  293. Interorgan ammonia metabolism in overnight fasted, metabolically stable patients with cirrhosis of the liver

    Article • European Journal of Gastroenterology & Hepatology, December 1999, Wolters Kluwer Health

    Professor Rajiv Jalan

  294. Enhanced renal ammonia production is a major cause of hyperammonemia after a simulated upper gastrointestinal bleed in patients with cirrhosis of the liver

    Article • European Journal of Gastroenterology & Hepatology, December 1999, Wolters Kluwer Health

    Professor Rajiv Jalan

  295. Moderate hypothermia for uncontrolled intracranial hypertension in acute liver failure

    Article • The Lancet, October 1999, Elsevier

    Professor Rajiv Jalan

  296. Diagnosis of hepatic encephalopathy: Willin vivo proton MRS play a role?

    Article • Hepatology, May 1999, Wiley

    Professor Rajiv Jalan

  297. Indocyanine green clearance reflects reperfusion injury following liver transplantation and is an early predictor of graft function

    Article • Journal of Hepatology, January 1999, Elsevier

    Professor Rajiv Jalan

  298. Simulation of a upper gastrointestinal bleed in patients with cirrhosis of the liver

    Article • European Journal of Gastroenterology & Hepatology, December 1998, Wolters Kluwer Health

    Professor Rajiv Jalan

  299. Prediction of cirrhosis in patients with chronic hepatitis C infection by artificial neural network analysis of virus and clinical factors

    Article • Journal of Viral Hepatitis, July 1998, Wiley

    Professor Rajiv Jalan

  300. Reply to Dr Larsen

    Article • Journal of Hepatology, June 1998, Elsevier

    Professor Rajiv Jalan

  301. Shunt insufficiency after TIPSS

    Article • CardioVascular and Interventional Radiology, May 1998, Springer Science + Business Media

    Professor Rajiv Jalan

  302. A randomized trial comparing transjugular intrahepatic portosystemic stent-shunt with variceal band ligation in the prevention of rebleeding from esophageal varices

    Article • European Journal of Gastroenterology & Hepatology, January 1998, Wolters Kluwer Health

    Professor Rajiv Jalan

  303. Efficacy of balloon angioplasty, restenting, and parallel shunt insertion for shunt insufficiency after transjugular intrahepatic portosystemic stent-shunt (TIPSS)

    Article • Minimally Invasive Therapy & Allied Technologies, January 1998, Taylor & Francis

    Professor Rajiv Jalan

  304. Hepatic encephalopathy and ascites

    Article • The Lancet, November 1997, Elsevier

    Professor Rajiv Jalan

  305. TIPSS trials: Design determines outcome

    Article • Hepatology, November 1997, Wiley

    Professor Rajiv Jalan

  306. TIPSS trials: Design determines outcome

    Article • Hepatology, November 1997, Wiley

    Professor Rajiv Jalan

  307. Elevation of intracranial pressure following transjugular intrahepatic portosystemic stent-shunt for variceal haemorrhage

    Article • Journal of Hepatology, November 1997, Elsevier

    Professor Rajiv Jalan

  308. A randomized trial comparing transjugular intrahepatic portosystemic stent-shunt with variceal band ligation in the prevention of rebleeding from esophageal varices.

    Article • Hepatology, November 1997, Wiley

    Professor Rajiv Jalan

  309. A randomized trial comparing transjugular intrahepatic portosystemic stent-shunt with variceal band ligation in the prevention of rebleeding from esophageal varices

    Article • Hepatology, November 1997, Wiley

    Professor Rajiv Jalan

  310. Shunt insufficiency after transjugular intrahepatic portosystemic stent-shunt: the whens, whys, hows and what should we do about it?

    Article • Clinical Radiology, May 1997, Elsevier

    Professor Rajiv Jalan

  311. Primary graft dysfunction after liver transplantation: From pathogenesis to prevention

    Article • Liver Transplantation and Surgery, March 1997, Wiley

    Professor Rajiv Jalan

  312. INFLUENCE OF CYCLIC GUANOSINE MONOPHOSPHATE CHANGES ON HEMODYNAMICS AFTER REPERFUSION IN LIVER TRANSPLANTATION

    Article • Transplantation, February 1997, Wolters Kluwer Health

    Professor Rajiv Jalan

  313. A comparison between gastric and oesophageal variceal haemorrhage treated with transjugular intrahepatic portosystemic stent shunt (TIPSS)

    Article • Alimentary Pharmacology & Therapeutics, February 1997, Wiley

    Professor Rajiv Jalan

  314. Transjugular intrahepatic portosystemic stent-shunt (TIPSS) insertion as a prelude to orthotopic liver transplantation in patients with severe portal hypertension

    Article • European Journal of Gastroenterology & Hepatology, December 1996, Wolters Kluwer Health

    Professor Rajiv Jalan

  315. Mechanisms of changes in renal handling of sodium following transjugular intrahepatic portal systemic stent-shunt (TIPSS)

    Article • European Journal of Gastroenterology & Hepatology, November 1996, Wolters Kluwer Health

    Professor Rajiv Jalan

  316. NEUTROPHIL ELASTASE: A DETERMINANT OF ENDOTHELIAL DAMAGE AND REPERFUSION INJURY AFTER LIVER TRANSPLANTATION?

    Article • Transplantation, October 1996, Wolters Kluwer Health

    Professor Rajiv Jalan

  317. pathogenesis and treatment of chronic hepatic encephalopathy

    Article • Alimentary Pharmacology & Therapeutics, October 1996, Wiley

    Professor Rajiv Jalan

  318. Differing actions of the acute administration of propranolol and isosorbide-5-mononitrate on the portal circulation

    Article • Alimentary Pharmacology & Therapeutics, October 1996, Wiley

    Professor Rajiv Jalan

  319. In vivo hepatic magnetic resonance spectroscopy: clinical or research tool?

    Article • Journal of Hepatology, September 1996, Elsevier

    Professor Rajiv Jalan

  320. Longterm follow up of transjugular intrahepatic portosystemic stent shunt (TIPSS) for the treatment of portal hypertension: results in 130 patients.

    Article • Gut, September 1996, BMJ

    Professor Rajiv Jalan

  321. Hepatic phosphorus-31 magnetic resonance spectroscopy in primary biliary cirrhosis and its relation to prognostic models.

    Article • Gut, July 1996, BMJ

    Professor Rajiv Jalan

  322. Review article: renal circulatory changes in cirrhosis--pathogenesis and therapeutic prospects.

    Article • Alimentary Pharmacology & Therapeutics, June 1996, Wiley

    Professor Rajiv Jalan

  323. Prospective evaluation of haematological alterations following the transjugular intrahepatic portosystemic stent-shunt (TIPSS)

    Article • European Journal of Gastroenterology & Hepatology, April 1996, Wolters Kluwer Health

    Professor Rajiv Jalan

  324. Transjugular intrahepatic portosystemic stent-shunt (TIPSS) occlusion and the role of biliary venous fistulae

    Article • Journal of Hepatology, February 1996, Elsevier

    Professor Rajiv Jalan

  325. Risk of intentional reversible thrombosis of transjugular intrahepatic portosystemic shunt.

    Article • Radiology, December 1995, Radiological Society of North America (RSNA)

    Professor Rajiv Jalan

  326. A prospective evaluation of changes in neuropsychological and liver function tests following transjugular intrahepatic portosystemic stent-shunt

    Article • Journal of Hepatology, December 1995, Elsevier

    Professor Rajiv Jalan

  327. In vitro proton (1H) magnetic resonance spectroscopy of the plasma in cirrhosis and changes following the transjugular intrahepatic portosystemic stentshunt (TIPSS) R. Jalan, Y.L. Chung, D.N.Redhead, *P.C. Hayes, J.D. Bell, R.E. Steiner, MR Unit, Hamme...

    Article • Hepatology, October 1995, Elsevier

    Professor Rajiv Jalan

  328. Transjugular intrahepatic portasystemic stent—shunt in the treatment of variceal haemorrhage

    Article • British Journal of Surgery, September 1995, Wiley

    Professor Rajiv Jalan

  329. Analysis of prognostic variables in the prediction of mortality, shunt failure, variceal rebleeding and encephalopathy following the transjugular intrahepatic protosystemic stent-shunt for variceal haemorrhage

    Article • Journal of Hepatology, August 1995, Elsevier

    Professor Rajiv Jalan

  330. The role of duplex and colour Doppler ultrasound in the follow-up evaluation of transjugular intrahepatic portosystemic stent shunt (TIPSS)

    Article • British Journal of Radiology, June 1995, British Institute of Radiology

    Professor Rajiv Jalan

  331. Gastric mucosal bleeding time in cirrhosis

    Article • Gastrointestinal Endoscopy, September 1994, Elsevier

    Professor Rajiv Jalan

  332. A PILOT STUDY OF INDOCYANINE GREEN CLEARANCE AS AN EARLY PREDICTOR OF GRAFT FUNCTION

    Article • Transplantation, July 1994, Wolters Kluwer Health

    Professor Rajiv Jalan

  333. A PILOT STUDY OF INDOCYANINE GREEN CLEARANCE AS AN EARLY PREDICTOR OF GRAFT FUNCTION

    Article • Transplantation, July 1994, Wolters Kluwer Health

    Professor Rajiv Jalan

  334. Gastric acid secretion rate and buffer content of the stomach after a rice- and a wheat-based meal in normal subjects and patients with duodenal ulcer.

    Article • Gut, May 1979, BMJ

    Professor Rajiv Jalan

  335. Testicular torsion in Henoch--Schonlein syndrome.

    Article • BMJ, April 1974, BMJ

    Professor Rajiv Jalan

  336. The role of inflammation in hepatic encephalopathy

    Article • Springer Science + Business Media

    Professor Rajiv Jalan

  337. Liver Failure and Intracerebral Hypertension

    Article • Springer Science + Business Media

    Professor Rajiv Jalan