All Stories

  1. Modulation of Hachiman defence by a type II toxin-antitoxin system via balancing trade-off between the fitness cost and antiphage activity
  2. Phosphorylation of the α subunit inhibits proteasome assembly and regulates cell cycle in an archaeon
  3. An Lrs14 family protein functions as a nucleoid-associated protein regulating cell cycle progression in Sulfolobales
  4. Cran1, member of a new class of OLD family ATPases, functions in cell cycle progression in an archaeon
  5. Substrate-induced remodeling of protein disordered loops activates Csm DNases
  6. Control of the archaeal DNA damage-responsive pathway by phosphorylation of Orc1-2, the global regulator in Saccharolobus islandicus
  7. TrmB1, a novel nucleoid-associated protein orchestrates dynamic chromatin organization and cell cycle progression in archaea
  8. Phosphorylation of the α subunit inhibits proteasome assembly and regulates cell division in an archaeon
  9. Universal Amplification-Free RNA Detection by Integrating CRISPR-Cas10 with Aptameric Graphene Field-Effect Transistor
  10. Base-modified nucleotides mediate immune signaling in bacteria
  11. A new class of OLD family ATPases Cran1 functions in cell cycle progression in an archaeon
  12. Rational design of unrestricted pRN1 derivatives and their application in the construction of a dual plasmid vector system for Saccharolobus islandicus
  13. Cbp1 and Cren7 form chromatin-like structures that ensure efficient transcription of long CRISPR arrays
  14. Catalytically inactive long prokaryotic Argonaute systems employ distinct effectors to confer immunity via abortive infection
  15. Rationale design of unrestricted pRN1 derivatives and their application in construction of a dual plasmid vector system forSaccharolobus islandicus
  16. The FHA domain protein ArnA functions as a global DNA damage response repressor in the hyperthermophilic archaeon Saccharolobus islandicus
  17. The abortive infection functions of CRISPR-Cas and Argonaute
  18. Cbp1-Cren7 chromatinization of CRISPR arrays favours transcription from leader-over cryptic promoters
  19. Inactive long prokaryotic Argonaute systems employ various effectors to confer immunity via abortive infection
  20. Harnessing the LdCsm RNA Detection Platform for Efficient microRNA Detection
  21. A novel RHH family transcription factor aCcr1 and its viral homologs dictate cell cycle progression in archaea
  22. Sulfolobus islandicus Employs Orc1-2-Mediated DNA Damage Response in Defense against Infection by SSV2
  23. Dissection of Functional Domains of Orc1-2, the Archaeal Global DNA Damage-Responsive Regulator
  24. Remodeling of a tripartite substrate-binding motif in the HD domain provides the mechanism for activation of CRISPR-Cas10 DNases
  25. Genomics, Transcriptomics, and Proteomics of SSV1 and Related Fusellovirus: A Minireview
  26. Inactivation of Target RNA Cleavage of a III-B CRISPR-Cas System Induces Robust Autoimmunity in Saccharolobus islandicus
  27. A Well-Conserved Archaeal B-Family Polymerase Functions as an Extender in Translesion Synthesis
  28. Enzymatic Switching Between Archaeal DNA Polymerases Facilitates Abasic Site Bypass
  29. Genome editing from Cas9 to IscB: Backwards and forwards towards new breakthroughs
  30. A well conserved archaeal B-family polymerase functions as a mismatch and lesion extender
  31. A type III-A CRISPR–Cas system mediates co-transcriptional DNA cleavage at the transcriptional bubbles in close proximity to active effectors
  32. Evolutionary Trajectory of the Replication Mode of Bacterial Replicons
  33. Purification and characterization of ribonucleoprotein effector complexes of Sulfolobus islandicus CRISPR-Cas systems
  34. Recombinant protein expression in Sulfolobus islandicus
  35. Antiviral Defense Mechanisms in Archaea
  36. CRISPR-Cas adaptive immune systems in Sulfolobales: genetic studies and molecular mechanisms
  37. A Membrane-Associated DHH-DHHA1 Nuclease Degrades Type III CRISPR Second Messenger
  38. Structures of the Cmr-β Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas
  39. A Unique B-Family DNA Polymerase Facilitating Error-Prone DNA Damage Tolerance in Crenarchaeota
  40. Structures of the Cmr-β Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas
  41. Characterization of a novel type III CRISPR-Cas effector provides new insights into the allosteric activation and suppression of the Cas10 DNase
  42. A Membrane-Associated Nuclease Degrades Cyclic Oligo-Adenylate and Deactivates Type III CRISPR Ribonuclease
  43. Characterization of a novel type III CRISPR-Cas effector provides new insights into the allosteric activation and suppression of the Cas10 DNase
  44. Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas
  45. Crenarchaeal 3D Genome: A Prototypical Chromosome Architecture for Eukaryotes
  46. Cmr3 regulates the suppression on cyclic oligoadenylate synthesis by tag complementarity in a Type III-B CRISPR-Cas system
  47. A seed motif for target RNA capture enables efficient immune defence by a type III-B CRISPR-Cas system
  48. Comparative genomics for non-O1/O139 Vibrio cholerae isolates recovered from the Yangtze River Estuary versus V. cholerae representative isolates from serogroup O1
  49. Molecular mechanisms of III-B CRISPR–Cas systems in archaea
  50. A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding
  51. Comprehensive search for accessory proteins encoded with archaeal and bacterial type III CRISPR-cas gene cassettes reveals 39 new cas gene families
  52. An Orc1/Cdc6 ortholog functions as a key regulator in the DNA damage response in Archaea
  53. A transcriptional factor B paralog functions as an activator to DNA damage-responsive expression in archaea
  54. Tolerance of Sulfolobus SMV1 virus to the immunity of I-A and III-B CRISPR-Cas systems in Sulfolobus islandicus
  55. A transcriptional factor B paralog functions as an activator to DNA damage-responsive expression in archaea
  56. Diversity and Contributions to Nitrogen Cycling and Carbon Fixation of Soil Salinity Shaped Microbial Communities in Tarim Basin
  57. Conserved accessory proteins encoded with archaeal and bacterial Type III CRISPR-Cas gene cassettes that may specifically modulate, complement or extend interference activity
  58. Type III CRISPR-Cas System: Introduction And Its Application for Genetic Manipulations
  59. In vivo and in vitro protein imaging in thermophilic archaea by exploiting a novel protein tag
  60. Cmr1 enables efficient RNA and DNA interference of a III-B CRISPR–Cas system by binding to target RNA and crRNA
  61. Allosteric regulation of Csx1, a type IIIB-associated CARF domain ribonuclease by RNAs carrying a tetraadenylate tail
  62. NQO-Induced DNA-Less Cell Formation Is Associated with Chromatin Protein Degradation and Dependent on A0A1-ATPase in Sulfolobus
  63. Coupling transcriptional activation of CRISPR–Cas system and DNA repair genes by Csa3a in Sulfolobus islandicus
  64. The extraordinary thermal stability of EstA from S. islandicus is independent of post translational modifications
  65. Reverse Gyrase Functions in Genome Integrity Maintenance by Protecting DNA Breaks In Vivo
  66. Genomic and transcriptomic analyses reveal distinct biological functions for cold shock proteins (VpaCspA and VpaCspD) in Vibrio parahaemolyticus CHN25 during low-temperature survival
  67. Genetic technologies for extremely thermophilic microorganisms of Sulfolobus, the only genetically tractable genus of crenarchaea
  68. Type III CRISPR-Cas System: Introduction And Its Application for Genetic Manipulations
  69. CRISPR History: Discovery, Characterization, and Prosperity
  70. A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction
  71. CRISPR-Cas type I-A Cascade complex couples viral infection surveillance to host transcriptional regulation in the dependence of Csa3b
  72. Major and minor crRNA annealing sites facilitate low stringency DNA protospacer binding prior to Type I-A CRISPR-Cas interference in Sulfolobus
  73. Diverse CRISPR-Cas responses and dramatic cellular DNA changes and cell death in pKEF9-conjugatedSulfolobusspecies
  74. Theapt/6-Methylpurine Counterselection System and Its Applications in Genetic Studies of the Hyperthermophilic Archaeon Sulfolobus islandicus
  75. Construction and characterization of three protein-targeting expression system inLactobacillus casei
  76. Heterologous Expression of Mannanase and Developing a New Reporter Gene System in Lactobacillus casei and Escherichia coli
  77. Transcriptome analysis of Sulfolobus solfataricus infected with two related fuselloviruses reveals novel insights into the regulation of CRISPR-Cas system
  78. Harnessing Type I and Type III CRISPR-Cas systems for genome editing
  79. Unravelling the Role of the F55 Regulator in the Transition from Lysogeny to UV Induction of Sulfolobus Spindle-Shaped Virus 1
  80. CRISPR-Cas Adaptive Immune Systems of the Sulfolobales: Unravelling Their Complexity and Diversity
  81. Archaeal Extrachromosomal Genetic Elements
  82. Genetic analysis of the Holliday junction resolvases Hje and Hjc in Sulfolobus islandicus
  83. Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR de novo spacer acquisition
  84. Efficient 5′-3′ DNA end resection by HerA and NurA is essential for cell viability in the crenarchaeon Sulfolobus islandicus
  85. An archaeal CRISPR type III-B system exhibiting distinctive RNA targeting features and mediating dual RNA and DNA interference
  86. Sulfolobus Replication Factor C Stimulates the Activity of DNA Polymerase B1
  87. Characterization of pMC11, a plasmid with dual origins of replication isolated from Lactobacillus casei MCJ and construction of shuttle vectors with each replicon
  88. Molecular biology of fuselloviruses and their satellites
  89. Nanobiomotors of archaeal DNA repair machineries: current research status and application potential
  90. A novel single-tailed fusiform Sulfolobus virus STSV2 infecting model Sulfolobus species
  91. Knockouts of RecA-Like Proteins RadC1 and RadC2 Have Distinct Responses to DNA Damage Agents in Sulfolobus islandicus
  92. Transcriptomic analysis of the SSV2 infection of Sulfolobus solfataricus with and without the integrative plasmid pSSVi
  93. Genomics and genetics of Sulfolobus islandicus LAL14/1, a model hyperthermophilic archaeon
  94. Novel insights into gene regulation of the rudivirus SIRV2 infectingSulfolobuscells
  95. Tlys, a Newly Identified Sulfolobus Spindle-Shaped Virus 1 Transcript Expressed in the Lysogenic State, Encodes a DNA-Binding Protein Interacting at the Promoters of the Early Genes
  96. Genetic determinants of PAM-dependent DNA targeting and pre-crRNA processing inSulfolobus islandicus
  97. A novel interference mechanism by a type IIIB CRISPR-Cmr module inSulfolobus
  98. Genetic manipulation inSulfolobus islandicusand functional analysis of DNA repair genes
  99. Specificity and Function of Archaeal DNA Replication Initiator Proteins
  100. A novel carboxyl-terminal protease derived from Paenibacillus lautus CHN26 exhibiting high activities at multiple sites of substrates
  101. Molecular cloning of a novel bioH gene from an environmental metagenome encoding a carboxylesterase with exceptional tolerance to organic solvents
  102. An archaeal protein evolutionarily conserved in prokaryotes is a zinc-dependent metalloprotease
  103. A Synthetic Arabinose-Inducible Promoter Confers High Levels of Recombinant Protein Expression in Hyperthermophilic Archaeon Sulfolobus islandicus
  104. Archaeal viruses—novel, diverse and enigmatic
  105. Dissection of the functional domains of an archaeal Holliday junction helicase
  106. Modulation of CRISPR locus transcription by the repeat-binding protein Cbp1 in Sulfolobus
  107. Development of a Simvastatin Selection Marker for a Hyperthermophilic Acidophile, Sulfolobus islandicus
  108. Exceptional thermal stability and organic solvent tolerance of an esterase expressed from a thermophilic host
  109. Deletion of the topoisomerase III gene in the hyperthermophilic archaeon Sulfolobus islandicus results in slow growth and defects in cell cycle control
  110. Genomic analysis of Acidianus hospitalis W1 a host for studying crenarchaeal virus and plasmid life cycles
  111. Sulfolobus Turreted Icosahedral Virus c92 Protein Responsible for the Formation of Pyramid-Like Cellular Lysis Structures
  112. Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE)
  113. C68 from theSulfolobus islandicusplasmid–virus pSSVx is a novel member of the AbrB-like transcription factor family
  114. Phenotypic, Proteomic, and Genomic Characterization of a Putative ABC-Transporter Permease Involved inListeria monocytogenesBiofilm Formation
  115. Archaeal promoter architecture and mechanism of gene activation: Figure 1
  116. CRISPR-based immune systems of the Sulfolobales: complexity and diversity
  117. Genome Analyses of Icelandic Strains of Sulfolobus islandicus, Model Organisms for Genetic and Virus-Host Interaction Studies
  118. Dynamic properties of the Sulfolobus CRISPR/Cas and CRISPR/Cmr systems when challenged with vector-borne viral and plasmid genes and protospacers
  119. Transcription termination in the plasmid/virus hybrid pSSVx from Sulfolobus islandicus
  120. Revealing the essentiality of multiple archaeal pcna genes using a mutant propagation assay based on an improved knockout method
  121. Four newly isolated fuselloviruses from extreme geothermal environments reveal unusual morphologies and a possible interviral recombination mechanism
  122. An upstream activation element exerting differential transcriptional activation on an archaeal promoter
  123. Unmarked gene deletion and host–vector system for the hyperthermophilic crenarchaeon Sulfolobus islandicus
  124. Genetic analyses in the hyperthermophilic archaeonSulfolobus islandicus
  125. A Putative ABC Transporter Is Involved in Negative Regulation of Biofilm Formation by Listeria monocytogenes
  126. Nucleotide sequence of pOLA52: A conjugative IncX1 plasmid from Escherichia coli which enables biofilm formation and multidrug efflux
  127. Transcriptional Analysis of the Genetic Element pSSVx: Differential and Temporal Regulation of Gene Expression Reveals Correlation between Transcription and Replication
  128. A novel Sulfolobus non-conjugative extrachromosomal genetic element capable of integration into the host genome and spreading in the presence of a fusellovirus
  129. The genome ofHyperthermus butylicus: a sulfur-reducing, peptide fermenting, neutrophilic Crenarchaeote growing up to 108 °C
  130. Novel bacterial sulfur oxygenase reductases from bioreactors treating gold-bearing concentrates
  131. Characterization of the Sulfolobus host–SSV2 virus interaction
  132. The Genome of Sulfolobus acidocaldarius, a Model Organism of the Crenarchaeota
  133. Sulfolobus tengchongensis Spindle-Shaped Virus STSV1: Virus-Host Interactions and Genomic Features
  134. Key Role of Cysteine Residues in Catalysis and Subcellular Localization of Sulfur Oxygenase-Reductase of Acidianus tengchongensis
  135. Novel RepA-MCM proteins encoded in plasmids pTAU4, pORA1 and pTIK4 fromSulfolobus neozealandicus
  136. Archaeal integrases and mechanisms of gene capture
  137. Relationships between fuselloviruses infecting the extremely thermophilic archaeon Sulfolobus: SSV1 and SSV2
  138. Genus-Specific Protein Binding to the Large Clusters of DNA Repeats (Short Regularly Spaced Repeats) Present in Sulfolobus Genomes
  139. Archaeal integrative genetic elements and their impact on genome evolution
  140. Mobile elements in archaeal genomes
  141. Mobile elements in archaeal genomes
  142. Sequences and Replication of Genomes of the Archaeal Rudiviruses SIRV1 and SIRV2: Relationships to the Archaeal Lipothrixvirus SIFV and Some Eukaryal Viruses
  143. The complete genome of the crenarchaeon Sulfolobus solfataricus P2
  144. Non-autonomous mobile elements in the crenarchaeon Sulfolobus solfataricus
  145. Genome evolution: Gene capture in archaeal chromosomes
  146. pING Family of Conjugative Plasmids from the Extremely Thermophilic Archaeon Sulfolobus islandicus: Insights into Recombination and Conjugation in Crenarchaeota
  147. Evolution of the family of pRN plasmids and their integrase-mediated insertion into the chromosome of the crenarchaeon Sulfolobus solfataricus
  148. Gene content and organization of a 281-kbp contig from the genome of the extremely thermophilic archaeon,Sulfolobus solfataricusP2
  149. A Bac Library and Paired-PCR Approach to Mapping and Completing the Genome Sequence ofSulfolobus SolfataricusP2
  150. Gene content and organization of a 281-kbp contig from the genome of the extremely thermophilic archaeon, Sulfolobus solfataricus P2
  151. The genetic element pSSVx of the extremely thermophilic crenarchaeon Sulfolobus is a hybrid between a plasmid and a virus
  152. Genetic profile of pNOB8 from Sulfolobus : the first conjugative plasmid from an archaeon
  153. Sulfolobus genome: from genomics to biology
  154. Completing the sequence of the Sulfolobus solfataricus P2 genome
  155. Genetic elements in the extremely thermophilic archaeon Sulfolobus
  156. Archaea and the new age of microorganisms
  157. Organization and expression of genes in the genomic region surrounding the glutamine synthetase gene Gln1 from Lotus japonicus
  158. Minimal enhancer elements of the leghemoglobinlba andlbc3 gene promoters fromGlycine max L. have different properties
  159. Comparative sequence analysis of cis elements present in Glycine max L. leghemoglobin lba and lbc3 genes