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  1. Stability and Chemical Conversion of the Purified Reference Material of Gymnodimine-A under Different Temperature and pH Conditions

    Article • Toxins, October 2022, MDPI AG

    Dr. Philipp Hess

  2. Comparative Study on the Performance of Three Detection Methods for the Quantification of Pacific Ciguatoxins in French Polynesian Strains of Gambierdiscus polynesiensis

    Article • Marine Drugs, May 2022, MDPI AG

    Dr. Philipp Hess

  3. Unraveling the Gonyaulax baltica Species Complex: Cyst–theca Relationship of Impagidinium variaseptum , Spiniferites pseudodelicatus sp. nov. and <...

    Article • Journal of Phycology, March 2022, Wiley

    Dr. Philipp Hess

  4. Sulfo-Gambierones, Two New Analogs of Gambierone Produced by Gambierdiscus excentricus

    Article • Marine Drugs, November 2021, MDPI AG

    Dr. Philipp Hess

  5. Deep-Water Fish Are Potential Vectors of Ciguatera Poisoning in the Gambier Islands, French Polynesia

    Article • Marine Drugs, November 2021, MDPI AG

    Dr. Philipp Hess

  6. Development of an Efficient Extraction Method for Harvesting Gymnodimine-A from Large-Scale Cultures of Karenia selliformis

    Article • Toxins, November 2021, MDPI AG

    Dr. Philipp Hess

  7. Tetrodotoxins in French Bivalve Mollusks—Analytical Methodology, Environmental Dynamics and Screening of Bacterial Strain Collections

    Article • Toxins, October 2021, MDPI AG

    Dr. Philipp Hess

  8. Toward Isolation of Palytoxins: Liquid Chromatography Coupled to Low- or High-Resolution Mass Spectrometry for the Study on the Impact of Drying Techniques, Solvents and Materials

    Article • Toxins, September 2021, MDPI AG

    Dr. Philipp Hess

  9. Toxicity Screening of a Gambierdiscus australes Strain from the Western Mediterranean Sea and Identification of a Novel Maitotoxin Analogue

    Article • Marine Drugs, August 2021, MDPI AG

    Dr. Philipp Hess

  10. Characterisation of ciguatoxins

    Article • EFSA Supporting Publications, May 2021, Wiley

    Dr. Philipp Hess

  11. Risk characterisation of ciguatera poisoning in Europe

    Article • EFSA Supporting Publications, May 2021, Wiley

    Dr. Philipp Hess

  12. Effects of pH and Nutrients (Nitrogen) on Growth and Toxin Profile of the Ciguatera-Causing Dinoflagellate Gambierdiscus polynesiensis (Dinophyceae)

    Article • Toxins, December 2020, MDPI AG

    Dr. Philipp Hess

  13. Evidence for the Range Expansion of Ciguatera in French Polynesia: A Revisit of the 2009 Mass-Poisoning Outbreak in Rapa Island (Australes Archipelago)

    Article • Toxins, December 2020, MDPI AG

    Dr. Philipp Hess

  14. Diversity and Toxicity of the Genus Coolia Meunier in Brazil, and Detection of 44-methyl Gambierone in Coolia tropicalis

    Article • Toxins, May 2020, MDPI AG

    Dr. Philipp Hess

  15. Assessment of Ciguatera and Other Phycotoxin-Related Risks in Anaho Bay (Nuku Hiva Island, French Polynesia): Molecular, Toxicological, and Chemical Analyses of Passive Samplers

    Article • Toxins, May 2020, MDPI AG

    Dr. Philipp Hess

  16. Use of Mass Spectrometry to Determine the Diversity of Toxins Produced by Gambierdiscus and Fukuyoa Species from Balearic Islands and Crete (Mediterranean Sea) and the Canary Islands (Northeast Atlantic)

    Article • Toxins, May 2020, MDPI AG

    Dr. Philipp Hess

  17. Liquid Chromatography Coupled to High-Resolution Mass Spectrometry for the Confirmation of Caribbean Ciguatoxin-1 as the Main Toxin Responsible for Ciguatera Poisoning Caused by Fish from European Atlantic Coasts

    Article • Toxins, April 2020, MDPI AG

    Dr. Philipp Hess

  18. Acute Oral Toxicity of Pinnatoxin G in Mice

    Article • Toxins, January 2020, MDPI AG

    Dr. Philipp Hess

  19. Ostreopsis cf. ovata (Dinophyceae) Molecular Phylogeny, Morphology, and Detection of Ovatoxins in Strains and Field Samples from Brazil

    Article • Toxins, January 2020, MDPI AG

    Dr. Philipp Hess

  20. Intraspecific Variability in the Toxin Production and Toxin Profiles of In Vitro Cultures of Gambierdiscus polynesiensis (Dinophyceae) from French Polynesia

    Article • Toxins, December 2019, MDPI AG

    Dr. Philipp Hess

  21. Ostreopsis cf. ovata Bloom in Currais, Brazil: Phylogeny, Toxin Profile and Contamination of Mussels and Marine Plastic Litter

    Article • Toxins, July 2019, MDPI AG

    Dr. Philipp Hess

  22. Azaspiracids Increase Mitochondrial Dehydrogenases Activity in Hepatocytes: Involvement of Potassium and Chloride Ions

    Article • Marine Drugs, May 2019, MDPI AG

    Dr. Philipp Hess

  23. Chemically mediated interactions between Microcystis and Planktothrix : impact on their growth, morphology and metabolic profiles

    Article • Environmental Microbiology, January 2019, Wiley

    Dr. Philipp Hess

  24. Tissue Distribution and Elimination of Ciguatoxins in Tridacna maxima (Tridacnidae, Bivalvia) Fed Gambierdiscus polynesiensis

    Article • Toxins, May 2018, MDPI AG

    Dr. Philipp Hess

  25. Metabolomic Profiles of Dinophysis acuminata and Dinophysis acuta Using Non-Targeted High-Resolution Mass Spectrometry: Effect of Nutritional Status and Prey

    Article • Marine Drugs, April 2018, MDPI AG

    Dr. Philipp Hess

  26. Toxicological Investigations on the Sea Urchin Tripneustes gratilla (Toxopneustidae, Echinoid) from Anaho Bay (Nuku Hiva, French Polynesia): Evidence for the Presence of Pacific Ciguatoxins

    Article • Marine Drugs, April 2018, MDPI AG

    Dr. Philipp Hess

  27. Toxic equivalency factors (TEFs) after acute oral exposure of azaspiracid 1, −2 and −3 in mice

    Article • Toxicology Letters, January 2018, Elsevier

    Dr. Philipp Hess

  28. Tectus niloticus (Tegulidae, Gastropod) as a Novel Vector of Ciguatera Poisoning: Detection of Pacific Ciguatoxins in Toxic Samples from Nuku Hiva Island (French Polynesia)

    Article • Toxins, December 2017, MDPI AG

    Dr. Philipp Hess

  29. Ciguatoxicity of Gambierdiscus and Fukuyoa species from the Caribbean and Gulf of Mexico

    Article • PLOS One, October 2017, PLOS

    Dr. Philipp Hess

  30. Relative molar response of lipophilic algal toxins in mass spectrometry

    Article • Rapid Communications in Mass Spectrometry, July 2017, Wiley

    Dr. Philipp Hess

  31. Maitotoxin-4, a Novel MTX Analog Produced by Gambierdiscus excentricus

    Article • Marine Drugs, July 2017, MDPI AG

    Dr. Philipp Hess

  32. Intoxikation durch marine Biotoxine

    Article • Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, May 2017, Springer Science + Business Media

    Dr. Philipp Hess

  33. Toxicity screening of 13 Gambierdiscus strains using neuro-2a and erythrocyte lysis bioassays

    Article • Harmful Algae, March 2017, Elsevier

    Dr. Philipp Hess

  34. Derivation of toxicity equivalency factors for marine biotoxins associated with Bivalve Molluscs

    Article • Trends in Food Science & Technology, January 2017, Elsevier

    Dr. Philipp Hess

  35. Production of BMAA and DAB by diatoms ( Phaeodactylum tricornutum , Chaetoceros sp., Chaetoceros calcitrans and, Thalassiosira pseudonana ) and bacteria isolated from a diatom culture

    Article • Harmful Algae, September 2016, Elsevier

    Dr. Philipp Hess

  36. Passive Sampling and High Resolution Mass Spectrometry for Chemical Profiling of French Coastal Areas with a Focus on Marine Biotoxins

    Article • Environmental Science & Technology, August 2016, American Chemical Society (ACS)

    Dr. Philipp Hess

  37. Toxin and Growth Responses of the Neurotoxic Dinoflagellate Vulcanodinium rugosum to Varying Temperature and Salinity

    Article • Toxins, May 2016, MDPI AG

    Dr. Philipp Hess

  38. Algal toxin profiles in Nigerian coastal waters (Gulf of Guinea) using passive sampling and liquid chromatography coupled to mass spectrometry

    Article • Toxicon, May 2016, Elsevier

    Dr. Philipp Hess

  39. Differentiation of gonyautoxins by ion mobility–mass spectrometry: A cationization study

    Article • International Journal of Mass Spectrometry, May 2016, Elsevier

    Dr. Philipp Hess

  40. Systematic detection of BMAA (β-N-methylamino-l-alanine) and DAB (2,4-diaminobutyric acid) in mollusks collected in shellfish production areas along the French coasts

    Article • Toxicon, February 2016, Elsevier

    Dr. Philipp Hess

  41. Azaspiracid Toxins: Toxicological Profile

    Article • January 2016, Springer Science + Business Media

    Dr. Philipp Hess

  42. Effects of Heating on Proportions of Azaspiracids 1–10 in Mussels (Mytilus edulis) and Identification of Carboxylated Precursors for Azaspiracids 5, 10, 13, and 15

    Article • Journal of Agricultural and Food Chemistry, December 2015, American Chemical Society (ACS)

    Dr. Philipp Hess

  43. Marine harmful algal blooms, human health and wellbeing: challenges and opportunities in the 21st century

    Article • Journal of the Marine Biological Association of the United Kingdom, November 2015, Cambridge University Press

    Dr. Philipp Hess

  44. Cyclic imine toxins: From shellfish poisoning to neuroscience: The case of acyl derivatives

    Article • Biochemical Pharmacology, October 2015, Elsevier

    Dr. Philipp Hess

  45. High resolution mass spectrometry for quantitative analysis and untargeted screening of algal toxins in mussels and passive samplers

    Article • Journal of Chromatography A, October 2015, Elsevier

    Dr. Philipp Hess

  46. Effect of Nitrate, Ammonium and Urea on Growth and Pinnatoxin G Production of Vulcanodinium rugosum

    Article • Marine Drugs, September 2015, MDPI AG

    Dr. Philipp Hess

  47. β-N-methylamino-l-alanine (BMAA) and isomers: Distribution in different food web compartments of Thau lagoon, French Mediterranean Sea

    Article • Marine Environmental Research, September 2015, Elsevier

    Dr. Philipp Hess

  48. Structure Elucidation, Relative LC–MS Response and In Vitro Toxicity of Azaspiracids 7–10 Isolated from Mussels (Mytilus edulis)

    Article • Journal of Agricultural and Food Chemistry, May 2015, American Chemical Society (ACS)

    Dr. Philipp Hess

  49. Characterization of ovatoxin-h, a new ovatoxin analog, and evaluation of chromatographic columns for ovatoxin analysis and purification

    Article • Journal of Chromatography A, April 2015, Elsevier

    Dr. Philipp Hess

  50. Azaspiracid Toxins: Toxicological Profile

    Article • January 2015, Springer Science + Business Media

    Dr. Philipp Hess

  51. Identification and separation of saxitoxins using hydrophilic interaction liquid chromatography coupled to traveling wave ion mobility-mass spectrometry

    Article • Journal of Mass Spectrometry, January 2015, Wiley

    Dr. Philipp Hess

  52. Effect of seawater salinity on pore-size distribution on a poly(styrene)-based HP20 resin and its adsorption of diarrhetic shellfish toxins

    Article • Journal of Chromatography A, December 2014, Elsevier

    Dr. Philipp Hess

  53. Extended evaluation of polymeric and lipophilic sorbents for passive sampling of marine toxins

    Article • Toxicon, December 2014, Elsevier

    Dr. Philipp Hess

  54. Beta-N-Methylamino-l-Alanine: LC-MS/MS Optimization, Screening of Cyanobacterial Strains and Occurrence in Shellfish from Thau, a French Mediterranean Lagoon

    Article • Marine Drugs, November 2014, MDPI AG

    Dr. Philipp Hess

  55. Isolation, Structure Elucidation, Relative LC-MS Response, and in Vitro Toxicity of Azaspiracids from the Dinoflagellate Azadinium spinosum

    Article • Journal of Natural Products, October 2014, American Chemical Society (ACS)

    Dr. Philipp Hess

  56. A mussel (Mytilus edulis) tissue certified reference material for the marine biotoxins azaspiracids

    Article • Analytical and Bioanalytical Chemistry, October 2014, Springer Science + Business Media

    Dr. Philipp Hess

  57. Oceans and Human Health: A rising tide of challenges and opportunities for Europe

    Article • Marine Environmental Research, August 2014, Elsevier

    Dr. Philipp Hess

  58. Complex Toxin Profile of French Mediterranean Ostreopsis cf. ovata Strains, Seafood Accumulation and Ovatoxins Prepurification

    Article • Marine Drugs, May 2014, MDPI AG

    Dr. Philipp Hess

  59. Azaspiracids

    Article • February 2014, Taylor & Francis

    Dr. Philipp Hess

  60. Azaspiracids

    Article • February 2014, Taylor & Francis

    Dr. Philipp Hess

  61. AZA

    Article • February 2014, Taylor & Francis

    Dr. Philipp Hess

  62. Cellular models and cytotoxicity of pinnatoxin-G and extracts of the dinoflagellate Vulcanodinium rugosum recently isolated from the French mediterranean lagoon of Ingril

    Article • Toxicon, December 2013, Elsevier

    Dr. Philipp Hess

  63. Pinnatoxin G is responsible for atypical toxicity in mussels (Mytilus galloprovincialis) and clams (Venerupis decussata) from Ingril, a French Mediterranean lagoon

    Article • Toxicon, December 2013, Elsevier

    Dr. Philipp Hess

  64. Study on the usefulness and limitations of a cytotoxicity bio-assay using KB cells to detect lipophilic toxins in shellfish matrices

    Article • Toxicon, December 2013, Elsevier

    Dr. Philipp Hess

  65. Cytotoxicity and mycotoxin production of shellfish-derivedPenicilliumspp., a risk for shellfish consumers

    Article • Letters in Applied Microbiology, September 2013, Wiley

    Dr. Philipp Hess

  66. Cytotoxicity, Fractionation and Dereplication of Extracts of the Dinoflagellate Vulcanodinium rugosum, a Producer of Pinnatoxin G

    Article • Marine Drugs, September 2013, MDPI AG

    Dr. Philipp Hess

  67. Effect of environmental and nutritional factors on growth and azaspiracid production of the dinoflagellate Azadinium spinosum

    Article • Harmful Algae, July 2013, Elsevier

    Dr. Philipp Hess

  68. Dissolved azaspiracids are absorbed and metabolized by blue mussels (Mytilus edulis)

    Article • Toxicon, April 2013, Elsevier

    Dr. Philipp Hess

  69. Oceans and Human Health (OHH): a European Perspective from the Marine Board of the European Science Foundation (Marine Board-ESF)

    Article • Microbial Ecology, March 2013, Springer Science + Business Media

    Dr. Philipp Hess

  70. Effect of Azadinium spinosum on the feeding behaviour and azaspiracid accumulation of Mytilus edulis

    Article • Aquatic Toxicology, November 2012, Elsevier

    Dr. Philipp Hess

  71. Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route

    Article • Toxicon, October 2012, Elsevier

    Dr. Philipp Hess

  72. Azaspiracid accumulation, detoxification and biotransformation in blue mussels (Mytilus edulis) experimentally fed Azadinium spinosum

    Article • Toxicon, September 2012, Elsevier

    Dr. Philipp Hess

  73. Production and Isolation of Azaspiracid-1 and -2 from Azadinium spinosum Culture in Pilot Scale Photobioreactors

    Article • Marine Drugs, June 2012, MDPI AG

    Dr. Philipp Hess

  74. Improved Isolation Procedure for Azaspiracids from Shellfish, Structural Elucidation of Azaspiracid-6, and Stability Studies

    Article • Journal of Agricultural and Food Chemistry, March 2012, American Chemical Society (ACS)

    Dr. Philipp Hess

  75. Quantitative analysis of azaspiracids in Azadinium spinosum cultures

    Article • Analytical and Bioanalytical Chemistry, February 2012, Springer Science + Business Media

    Dr. Philipp Hess

  76. The role of Azadinium spinosum (Dinophyceae) in the production of azaspiracid shellfish poisoning in mussels

    Article • Harmful Algae, September 2011, Elsevier

    Dr. Philipp Hess

  77. Combined oral toxicity of azaspiracid-1 and yessotoxin in female NMRI mice

    Article • Toxicon, May 2011, Elsevier

    Dr. Philipp Hess

  78. A mussel tissue certified reference material for multiple phycotoxins. Part 1: design and preparation

    Article • Analytical and Bioanalytical Chemistry, March 2011, Springer Science + Business Media

    Dr. Philipp Hess

  79. The effects of growth phase and light intensity on toxin production by Dinophysis acuminata from the northeastern United States

    Article • Harmful Algae, March 2011, Elsevier

    Dr. Philipp Hess

  80. Sub-lethal dosing of azaspiracid-1 in female NMRI mice

    Article • Toxicon, December 2010, Elsevier

    Dr. Philipp Hess

  81. Production of diarrhetic shellfish poisoning toxins and pectenotoxins at depths within and below the euphotic zone

    Article • Toxicon, December 2010, Elsevier

    Dr. Philipp Hess

  82. The preparation of certified calibration solutions for azaspiracid-1, -2, and -3, potent marine biotoxins found in shellfish

    Article • Analytical and Bioanalytical Chemistry, September 2010, Springer Science + Business Media

    Dr. Philipp Hess

  83. Requirements for screening and confirmatory methods for the detection and quantification of marine biotoxins in end-product and official control

    Article • Analytical and Bioanalytical Chemistry, January 2010, Springer Science + Business Media

    Dr. Philipp Hess

  84. Phycotoxins: chemistry, mechanisms of action and shellfish poisoning

    Article • January 2010, Springer Science + Business Media

    Dr. Philipp Hess

  85. DSP toxin production de novo in cultures of Dinophysis acuminata (Dinophyceae) from North America

    Article • Harmful Algae, September 2009, Elsevier

    Dr. Philipp Hess

  86. Performance of the EU-harmonised mouse bioassay for lipophilic toxins for the detection of azaspiracids in naturally contaminated mussel (Mytilus edulis) hepatopancreas tissue homogenates characterised by liquid chromatography coupled to tandem mass sp...

    Article • Toxicon, June 2009, Elsevier

    Dr. Philipp Hess

  87. Solid phase extraction for removal of matrix effects in lipophilic marine toxin analysis by liquid chromatography-tandem mass spectrometry

    Article • Analytical and Bioanalytical Chemistry, April 2009, Springer Science + Business Media

    Dr. Philipp Hess

  88. Comparative accumulation and composition of lipophilic marine biotoxins in passive samplers and in mussels (M. edulis) on the West Coast of Ireland

    Article • Harmful Algae, February 2009, Elsevier

    Dr. Philipp Hess

  89. Formation of Azaspiracids-3, -4, -6, and -9 via Decarboxylation of Carboxyazaspiracid Metabolites from Shellfish

    Article • Journal of Agricultural and Food Chemistry, January 2009, American Chemical Society (ACS)

    Dr. Philipp Hess

  90. Evaluation of Various pH and Temperature Conditions on the Stability of Azaspiracids and Their Importance in Preparative Isolation and Toxicological Studies

    Article • Analytical Chemistry, December 2008, American Chemical Society (ACS)

    Dr. Philipp Hess

  91. Field and mesocosm trials on passive sampling for the study of adsorption and desorption behaviour of lipophilic toxins with a focus on OA and DTX1

    Article • Harmful Algae, August 2008, Elsevier

    Dr. Philipp Hess

  92. Confirmation by LC–MS/MS of azaspiracids in shellfish from the Portuguese north-western coast

    Article • Toxicon, June 2008, Elsevier

    Dr. Philipp Hess

  93. Azaspiracid Shellfish Poisoning: A Review on the Chemistry, Ecology, and Toxicology with an Emphasis on Human Health Impacts

    Article • Marine Drugs, June 2008, MDPI AG

    Dr. Philipp Hess

  94. Azaspiracid Shellfish Poisoning: A Review on the Chemistry, Ecology, and Toxicology with an Emphasis on Human Health Impacts

    Article • Marine Drugs, May 2008, MDPI AG

    Dr. Philipp Hess

  95. Effects of cooking and heat treatment on concentration and tissue distribution of okadaic acid and dinophysistoxin-2 in mussels (Mytilus edulis)

    Article • Toxicon, May 2008, Elsevier

    Dr. Philipp Hess

  96. Clarification of the C-35 Stereochemistries of Dinophysistoxin-1 and Dinophysistoxin-2 and Its Consequences for Binding to Protein Phosphatase

    Article • Chemical Research in Toxicology, December 2007, American Chemical Society (ACS)

    Dr. Philipp Hess

  97. Freeze-drying for the stabilisation of shellfish toxins in mussel tissue (Mytilus edulis) reference materials

    Article • Analytical and Bioanalytical Chemistry, January 2007, Springer Science + Business Media

    Dr. Philipp Hess

  98. Tissue distribution and effects of heat treatments on the content of domoic acid in blue mussels, Mytilus edulis

    Article • Toxicon, March 2006, Elsevier

    Dr. Philipp Hess

  99. Hydrophilic interaction liquid chromatography–mass spectrometry for the analysis of paralytic shellfish poisoning (PSP) toxins

    Article • Journal of Chromatography A, July 2005, Elsevier

    Dr. Philipp Hess

  100. Determination of paralytic shellfish poisoning toxins by high-performance ion-exchange chromatography

    Article • Journal of Chromatography A, September 2001, Elsevier

    Dr. Philipp Hess

  101. Chapter 2 Separation, clean-up and recoveries of persistent trace organic contaminants from soils, sediment and biological matrices

    Article • January 2000, Elsevier

    Dr. Philipp Hess

  102. Chapter 6 Methods for the determination and evaluation of chlorinated biphenyls (CBs) in environmental matrices

    Article • January 2000, Elsevier

    Dr. Philipp Hess

  103. Chemistry, Origins, and Distribution of Yessotoxin and its Analogues

    Article • Wiley

    Dr. Philipp Hess