All Stories

  1. Simplified PCR-Based Quantification of Proteins with DNA Aptamers and Methylcellulose as a Blocking Agent

    Article • International Journal of Molecular Sciences, December 2023, MDPI AG

    Dr Petr Draber

  2. Enhanced Membrane Fluidization and Cholesterol Displacement by 1-Heptanol Inhibit Mast Cell Effector Functions

    Article • Cells, August 2023, MDPI AG

    Dr Petr Draber

  3. Simultaneous reduction of all ORMDL proteins decreases the threshold of mast cell activation

    Article • Scientific Reports, June 2023, Springer Science + Business Media

    Dr Petr Draber

  4. Pentacyclic triterpenoid ursolic acid interferes with mast cell activation via a lipid-centric mechanism affecting FcεRI signalosome functions

    Article • Journal of Biological Chemistry, November 2022, Elsevier

    Dr Petr Draber

  5. Molecular Mechanisms of Mast Cell Activation by Cholesterol-Dependent Cytolysins

    Article • Frontiers in Immunology, June 2021, Frontiers

    Dr Petr Draber

  6. ORMDL2 Deficiency Potentiates the ORMDL3-Dependent Changes in Mast Cell Signaling

    Article • Frontiers in Immunology, February 2021, Frontiers

    Dr Petr Draber

  7. Crosstalk between ORMDL3, serine palmitoyltransferase, and 5-lipoxygenase in the sphingolipid and eicosanoid metabolic pathways

    Article • Journal of Lipid Research, January 2021, Elsevier

    Dr Petr Draber

  8. Tetraspanins in the regulation of mast cell function

    Article • Medical Microbiology and Immunology, June 2020, Springer Science + Business Media

    Dr Petr Draber

  9. Triacylglycerol‐Rich Oils of Marine Origin are Optimal Nutrients for Induction of Polyunsaturated Docosahexaenoic Acid Ester of Hydroxy Linoleic Acid (13‐DHAHLA) with Anti‐Inflammatory Properties in Mice

    Article • Molecular Nutrition & Food Research, April 2020, Wiley

    Dr Petr Draber

  10. Cytoskeletal Protein 4.1R Is a Positive Regulator of the FcεRI Signaling and Chemotaxis in Mast Cells

    Article • Frontiers in Immunology, January 2020, Frontiers

    Dr Petr Draber

  11. Carboxymethylcellulose enhances the production of single-stranded DNA aptamers generated by asymmetric PCR

    Article • Analytical Biochemistry, January 2020, Elsevier

    Dr Petr Draber

  12. Mast Cell Migration and Chemotaxis Assayed by Microscopy

    Article • January 2020, Springer Science + Business Media

    Dr Petr Draber

  13. The transmembrane adaptor protein NTAL limits mast cell chemotaxis toward prostaglandin E 2

    Article • Science Signaling, November 2018, American Association for the Advancement of Science

    Dr Petr Draber

  14. Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-Mediated Mast Cell Activation, Independent of the Transmembrane Adaptor PAG/CSK-Binding Protein

    Article • Frontiers in Immunology, August 2018, Frontiers

    Dr Petr Draber

  15. Changing the threshold-Signals and mechanisms of mast cell priming

    Article • Immunological Reviews, February 2018, Wiley

    Dr Petr Draber

  16. Positive and Negative Signals in Mast Cell Activation

    Article • Trends in Immunology, September 2017, Elsevier

    Dr Petr Draber

  17. Tetraspanins and Transmembrane Adaptor Proteins As Plasma Membrane Organizers—Mast Cell Case

    Article • Frontiers in Cell and Developmental Biology, May 2016, Frontiers

    Dr Petr Draber

  18. Signal transduction and chemotaxis in mast cells

    Article • European Journal of Pharmacology, May 2016, Elsevier

    Dr Petr Draber

  19. Signal transduction imunoreceptors IgE

    Article • Allergy, March 2016, Wiley

    Dr Petr Draber

  20. New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling

    Article • Molecular and Cellular Biology, February 2016, ASM Journals

    Dr Petr Draber

  21. Ethanol Inhibits High-Affinity Immunoglobulin E Receptor (FcεRI) Signaling in Mast Cells by Suppressing the Function of FcεRI-Cholesterol Signalosome

    Article • PLOS One, December 2015, PLOS

    Dr Petr Draber

  22. Negative regulatory roles of ORMDL3 in the FcεRI-triggered expression of proinflammatory mediators and chemotactic response in murine mast cells

    Article • Cellular and Molecular Life Sciences, September 2015, Springer Science + Business Media

    Dr Petr Draber

  23. Real-time PCR-based genotyping from whole blood using Taq DNA polymerase and a buffer supplemented with 1,2-propanediol and trehalose

    Article • Journal of Immunological Methods, January 2015, Elsevier

    Dr Petr Draber

  24. Transmembrane Adaptor Protein PAG/CBP Is Involved in both Positive and Negative Regulation of Mast Cell Signaling

    Article • Molecular and Cellular Biology, September 2014, ASM Journals

    Dr Petr Draber

  25. Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation

    Article • September 2014, Springer Science + Business Media

    Dr Petr Draber

  26. Molecular targets on mast cells and basophils for novel therapies

    Article • Journal of Allergy and Clinical Immunology, September 2014, Elsevier

    Dr Petr Draber

  27. Multiple Regulatory Roles of the Mouse Transmembrane Adaptor Protein NTAL in Gene Transcription and Mast Cell Physiology

    Article • PLOS One, August 2014, PLOS

    Dr Petr Draber

  28. Gold nanoparticle-based immuno-PCR for detection of tau protein in cerebrospinal fluid

    Article • Journal of Immunological Methods, April 2014, Elsevier

    Dr Petr Draber

  29. Microscopy Assays for Evaluation of Mast Cell Migration and Chemotaxis

    Article • January 2014, Springer Science + Business Media

    Dr Petr Draber

  30. Quantification of α-tubulin isotypes by sandwich ELISA with signal amplification through biotinyl-tyramide or immuno-PCR

    Article • Journal of Immunological Methods, September 2013, Elsevier

    Dr Petr Draber

  31. Cross-talk between Tetraspanin CD9 and Transmembrane Adaptor Protein Non-T Cell Activation Linker (NTAL) in Mast Cell Activation and Chemotaxis

    Article • Journal of Biological Chemistry, April 2013, Elsevier

    Dr Petr Draber

  32. Fc receptor-γ subunits with both polar or non-polar amino acids at position of T22 are capable of restoring surface expression of the high-affinity IgE receptor and degranulation in γ subunit-deficient rat basophilic leukemia cells

    Article • Molecular Immunology, March 2013, Elsevier

    Dr Petr Draber

  33. Mast Cell Chemotaxis – Chemoattractants and Signaling Pathways

    Article • Frontiers in Immunology, January 2012, Frontiers

    Dr Petr Draber

  34. Novel Mechanism for FcϵRI-mediated Signal Transducer and Activator of Transcription 5 (STAT5) Tyrosine Phosphorylation and the Selective Influence of STAT5B over Mast Cell Cytokine Production

    Article • Journal of Biological Chemistry, January 2012, Elsevier

    Dr Petr Draber

  35. Transmembrane Adaptor Proteins in the High-Affinity IgE Receptor Signaling

    Article • Frontiers in Immunology, January 2012, Frontiers

    Dr Petr Draber

  36. Rapid and sensitive detection of cytokines using functionalized gold nanoparticle-based immuno-PCR, comparison with immuno-PCR and ELISA

    Article • Journal of Immunological Methods, August 2011, Elsevier

    Dr Petr Draber

  37. 1,2-propanediol-trehalose mixture as a potent quantitative real-time PCR enhancer

    Article • BMC Biotechnology, April 2011, Springer Science + Business Media

    Dr Petr Draber

  38. STIM1-Directed Reorganization of Microtubules in Activated Mast Cells

    Article • The Journal of Immunology, January 2011, Oxford University Press (OUP)

    Dr Petr Draber

  39. The transmembrane adaptor protein NTAL signals to mast cell cytoskeleton via the small GTPase Rho

    Article • European Journal of Immunology, October 2010, Wiley

    Dr Petr Draber

  40. What precedes the initial tyrosine phosphorylation of the high affinity IgE receptor in antigen‐activated mast cell?

    Article • FEBS Letters, September 2010, Wiley

    Dr Petr Draber

  41. Down-regulation of Protein-tyrosine Phosphatases Activates an Immune Receptor in the Absence of Its Translocation into Lipid Rafts

    Article • Journal of Biological Chemistry, April 2010, Elsevier

    Dr Petr Draber

  42. Vacuolin-1-modulated exocytosis and cell resealing in mast cells

    Article • Cellular Signalling, August 2009, Elsevier

    Dr Petr Draber

  43. Engagement of Phospholipid Scramblase 1 in Activated Cells

    Article • Journal of Biological Chemistry, April 2008, Elsevier

    Dr Petr Draber

  44. Topography of signaling molecules as detected by electron microscopy on plasma membrane sheets isolated from non-adherent mast cells

    Article • Journal of Immunological Methods, December 2007, Elsevier

    Dr Petr Draber

  45. Preformed STAT3 transducer complexes in human HepG2 cells and rat hepatocytes

    Article • Cellular Signalling, November 2007, Elsevier

    Dr Petr Draber

  46. Regulation of Ca2+ Signaling in Mast Cells by Tyrosine-Phosphorylated and Unphosphorylated Non-T Cell Activation Linker

    Article • The Journal of Immunology, October 2007, Oxford University Press (OUP)

    Dr Petr Draber

  47. Non-apoptotic Phosphatidylserine Externalization Induced by Engagement of Glycosylphosphatidylinositol-anchored Proteins

    Article • Journal of Biological Chemistry, April 2007, Elsevier

    Dr Petr Draber

  48. Changes in GM1 ganglioside content and localization in cholestatic rat liver

    Article • Glycoconjugate Journal, February 2007, Springer Science + Business Media

    Dr Petr Draber

  49. Topography of plasma membrane microdomains and its consequences for mast cell signaling

    Article • European Journal of Immunology, October 2006, Wiley

    Dr Petr Draber

  50. Regulation of Microtubule Formation in Activated Mast Cells by Complexes of γ-Tubulin with Fyn and Syk Kinases

    Article • The Journal of Immunology, June 2006, Oxford University Press (OUP)

    Dr Petr Draber

  51. Lifting the fog in store-operated Ca2+ entry

    Article • Trends in Immunology, December 2005, Elsevier

    Dr Petr Draber

  52. Regulation of Cys-Based Protein Tyrosine Phosphatases Via Reactive Oxygen and Nitrogen Species in Mast Cells and Basophils

    Article • Current Medicinal Chemistry, August 2005, Bentham Science Publishers

    Dr Petr Draber

  53. Negative Regulation of Mast Cell Signaling and Function by the Adaptor LAB/NTAL

    Article • Journal of Experimental Medicine, October 2004, Rockefeller University Press

    Dr Petr Draber

  54. Signaling assemblies formed in mast cells activated via Fcϵ receptor I dimers

    Article • European Journal of Immunology, July 2004, Wiley

    Dr Petr Draber

  55. NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc RI aggregation

    Article • Blood, July 2004, American Society of Hematology

    Dr Petr Draber

  56. Modulation of the Fce Receptor I Signaling by Tyrosine Kinase Inhibitors: Search for Therapeutic Targets of Inflammatory and Allergy Diseases

    Article • Current Pharmaceutical Design, June 2004, Bentham Science Publishers

    Dr Petr Draber

  57. Involvement of filamentous actin in setting the threshold for degranulation in mast cells

    Article • European Journal of Immunology, May 2004, Wiley

    Dr Petr Draber

  58. Positive and negative regulation of Fcϵ receptor I‐mediated signaling events by Lyn kinase C‐terminal tyrosine phosphorylation

    Article • European Journal of Immunology, March 2004, Wiley

    Dr Petr Draber

  59. One-tube semi-nested PCR-ELISA for the detection of human cytomegalovirus DNA sequences; comparison with hybridization-based and semi-nested-based PCR-ELISA procedures

    Article • Journal of Immunological Methods, December 2003, Elsevier

    Dr Petr Draber

  60. Exogenous Administration of Gangliosides Inhibits FcεRI-Mediated Mast Cell Degranulation by Decreasing the Activity of Phospholipase Cγ

    Article • The Journal of Immunology, October 2003, Oxford University Press (OUP)

    Dr Petr Draber

  61. A role of tyrosine kinase Syk during neuronal differentiation of raurine embryonal carcinoma cells P19, stimulated by retinoic acid

    Article • Biopolymers and Cell, September 2003, Institute of Molecular Biology and Genetics (NAS Ukraine)

    Dr Petr Draber

  62. Non–T Cell Activation Linker (NTAL)

    Article • Journal of Experimental Medicine, December 2002, Rockefeller University Press

    Dr Petr Draber

  63. Lipid rafts in mast cell signaling

    Article • Molecular Immunology, September 2002, Elsevier

    Dr Petr Draber

  64. A novel lipid raft-associated glycoprotein, TEC-21, activates rat basophilic leukemia cells independently of the type 1 Fcε receptor

    Article • International Immunology, February 2002, Oxford University Press (OUP)

    Dr Petr Draber

  65. Nonreceptor Protein Tyrosine and Lipid Phosphatases in Type I Fcε Receptor-Mediated Activation of Mast Cells and Basophils

    Article • International Archives of Allergy and Immunology, January 2002, Karger Publishers

    Dr Petr Draber

  66. Structure-Function Analysis of Lyn Kinase Association with Lipid Rafts and Initiation of Early Signaling Events after Fcɛ Receptor I Aggregation

    Article • Molecular and Cellular Biology, December 2001, ASM Journals

    Dr Petr Draber

  67. Carcinoembryonic antigen-related cell adhesion molecule 1 is the 85-kilodalton pronase-resistant biliary glycoprotein in the cholesterol crystallization promoting low density protein-lipid complex

    Article • Hepatology, December 2001, Wolters Kluwer Health

    Dr Petr Draber

  68. Lipid Rafts and Their Role in Signal Transduction-Mast Cells as a Model

    Article • Trends in Glycoscience and Glycotechnology, January 2001, Forum: Carbohydrates Coming of Age

    Dr Petr Draber

  69. Soluble isoforms of CEACAM1 containing the A2 domain: increased serum levels in patients with obstructive jaundice and differences in 3‐fucosyl‐N‐acetyl‐lactosamine moiety

    Article • Immunology, October 2000, Wiley

    Dr Petr Draber

  70. The Specificity for the Differentiation Blocking Activity of Carcinoembryonic Antigen Resides in Its Glycophosphatidyl-Inositol Anchor

    Article • Journal of Cell Biology, August 2000, Rockefeller University Press

    Dr Petr Draber

  71. New specificity and yield enhancer of polymerase chain reactions

    Article • Nucleic Acids Research, July 2000, Oxford University Press (OUP)

    Dr Petr Draber

  72. Protein tyrosine kinase p53/p56lyn forms complexes with γ-tubulin in rat basophilic leukemia cells

    Article • International Immunology, November 1999, Oxford University Press (OUP)

    Dr Petr Draber

  73. Redefined Nomenclature for Members of the Carcinoembryonic Antigen Family

    Article • Experimental Cell Research, November 1999, Elsevier

    Dr Petr Draber

  74. Comparison of the expression of specific cell surface epitopes on in vitro fertilized and parthenogenetic bovine embryos

    Article • The Journal of Experimental Zoology, September 1999, Wiley

    Dr Petr Draber

  75. Requirement for a Negative Charge at Threonine 60 of the FcRγ for Complete Activation of Syk

    Article • Journal of Biological Chemistry, August 1999, Elsevier

    Dr Petr Draber

  76. Cytochemical localization of GalNAc and GalNAcβ1,4Galβ1,4 disaccharide in mouse zona pellucida

    Article • Cell and Tissue Research, January 1999, Springer Science + Business Media

    Dr Petr Draber

  77. Functional heterogeneity of Thy-1 membrane microdomains in rat basophilic leukemia cells

    Article • European Journal of Immunology, June 1998, Wiley

    Dr Petr Draber

  78. Lex glycosphingolipids-mediated cell aggregation

    Article • Glycobiology, February 1998, Oxford University Press (OUP)

    Dr Petr Draber

  79. The stage-specific expression of TEC-1, -2, -3, and -4 antigens on bovine preimplantation embryos

    Article • Molecular Reproduction and Development, January 1998, Wiley

    Dr Petr Draber

  80. Protein tyrosine kinase Syk is involved in Thy‐1 signaling in rat basophilic leukemia cells

    Article • European Journal of Immunology, December 1997, Wiley

    Dr Petr Draber

  81. Inhibition of murine macrophage nitric oxide synthase expression by a pivoxil prodrug of antiviral acyclic nucleotide analogue 9-(2-phosphonomethoxyethyl)adenine

    Article • Biochemical Pharmacology, October 1997, Elsevier

    Dr Petr Draber

  82. Src family‐selective tyrosine kinase inhibitor, PP1, inhibits both FcεRI‐ and Thy‐1‐mediated activation of rat basophilic leukemia cells

    Article • European Journal of Immunology, August 1997, Wiley

    Dr Petr Draber

  83. Direct interaction of Syk and Lyn protein tyrosine kinases in rat basophilic leukemia cells activated via type I Fcε receptors

    Article • European Journal of Immunology, January 1997, Wiley

    Dr Petr Draber

  84. Carbohydrate-Mediated Sorting in Aggregating Embryonal Carcinoma Cells

    Article • Biochemical and Biophysical Research Communications, July 1996, Elsevier

    Dr Petr Draber

  85. Characterization of Fcγ receptors on rat mucosal mast cells using a mutant FcϵRI‐deficient rat basophilic leukemia line

    Article • European Journal of Immunology, October 1995, Wiley

    Dr Petr Draber

  86. Thy‐1‐mediated activation of rat basophilic leukemia cells does not require co‐expression of the high‐affinity IgE receptor

    Article • European Journal of Immunology, September 1995, Wiley

    Dr Petr Draber

  87. Aggregation of Thy-1 Glycoprotein Induces Tyrosine Phosphorylation of Different Proteins in Isolated Rat Mast Cells and Rat Basophilic Leukemia Cells

    Article • January 1995, Springer Science + Business Media

    Dr Petr Draber

  88. Retinoic acid‐induced changes in differentiation‐defective embryonal carcinoma RAC65 cells

    Article • FEBS Letters, October 1992, Wiley

    Dr Petr Draber

  89. Inhibition of fertilization by a monoclonal antibody recognizing the oligosaccharide sequence Ga1NAcβ1→4Ga1β1→4 on the mouse zona pellucida

    Article • Journal of Reproductive Immunology, April 1992, Elsevier

    Dr Petr Draber

  90. Functional expression of the endogenous Thy‐1 gene and the transfected murine Thy‐1.2 gene in rat basophilic leukemia cells

    Article • European Journal of Immunology, July 1991, Wiley

    Dr Petr Draber

  91. Expression of Developmentally Regulated Genes in Embryonal Carcinoma Cells

    Article • January 1991, Springer Science + Business Media

    Dr Petr Draber

  92. Unusual stage-specific embryonic antigen (TEC-4) defined by a monoclonal antibody to embryonal carcinoma cells defective in the expression of embryoglycan.

    Article • Proceedings of the National Academy of Sciences, December 1989, Proceedings of the National Academy of Sciences

    Dr Petr Draber

  93. Inhibition of adhesion of F9 embryonal carcinoma cells to substratum by a novel monoclonal antibody, TEC-05, reactive with a developmentally regulated carbohydrate epitope

    Article • Differentiation, May 1988, Elsevier

    Dr Petr Draber

  94. Expression of mouse embryonic epitope TEC-2 on human carcinoma-derived cell lines and characterization of its glycoprotein carriers

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, March 1988, Elsevier

    Dr Petr Draber

  95. Differential expression of mouse embryonic antigens TEC-1 and TEC-2 in the epididymis of four rodent species

    Article • Cell Differentiation, September 1987, Elsevier

    Dr Petr Draber

  96. Mutants of embryonal carcinoma cells defective in the expression of embryoglycan.

    Article • Proceedings of the National Academy of Sciences, August 1987, Proceedings of the National Academy of Sciences

    Dr Petr Draber

  97. The epitope of mouse embryonic antigen(s) recognized by monoclonal antibody TEC-02 is a carbohydrate carried by high-molecular-weight glycoconjugates

    Article • Cell Differentiation, July 1987, Elsevier

    Dr Petr Draber

  98. Developmentally regulated surface structures of teratocarcinoma stem cells studied by mutant cell lines

    Article • Cell Differentiation, December 1984, Elsevier

    Dr Petr Draber

  99. Differentiation antigens of mouse teratocarcinoma stem cells defined by monoclonal antibodies

    Article • Cell Differentiation, December 1984, Elsevier

    Dr Petr Draber

  100. Localization of mouse TEC-1,2,3 antigens in adult and fetal tissues in the rat and human

    Article • Cell Differentiation, December 1984, Elsevier

    Dr Petr Draber

  101. Relationship of F9 antigens to spermatogenic cell antigens

    Article • Cell Differentiation, December 1984, Elsevier

    Dr Petr Draber

  102. Cytotoxicity of plant lectins for mouse embryonal carcinoma cells

    Article • Somatic Cell and Molecular Genetics, September 1984, Springer Science + Business Media

    Dr Petr Draber

  103. Isolation and partial characterization of lectin-resistant F9 cells

    Article • Somatic Cell and Molecular Genetics, September 1984, Springer Science + Business Media

    Dr Petr Draber

  104. Autoimmune damage to spermatogenesis in rodents immunized with mouse F9 embryonic carcinoma cells.

    Article • Proceedings of the National Academy of Sciences, January 1983, Proceedings of the National Academy of Sciences

    Dr Petr Draber

  105. Mechanism of the inhibitory effect of hydrocortisone on concanavalin A-induced activation of thymus cells. Role of interleukins

    Article • International Journal of Immunopharmacology, January 1982, Elsevier

    Dr Petr Draber

  106. Biological activity of hormonally active and non-active androgen derivatives

    Article • International Journal of Immunopharmacology, January 1982, Elsevier

    Dr Petr Draber

  107. Expression of T-cell differentiation antigens on activated thymocytes

    Article • Cellular Immunology, November 1981, Elsevier

    Dr Petr Draber

  108. Identification and characterization of immature thymocytes responsive to T cell growth factor

    Article • European Journal of Immunology, January 1981, Wiley

    Dr Petr Draber

  109. ADDITION OF SERUM TO THE MEDIUM USED FOR PREPARATION OF CELL SUSPENSIONS AS A POSSIBLE SOURCE OF ARTIFACTS IN CELL‐MEDIATED REACTIONS STUDIED BY MEANS OF THE POPLITEAL LYMPH NODE TEST

    Article • International Journal of Immunogenetics, December 1980, Wiley

    Dr Petr Draber

  110. ESTABLISHMENT AND CHARACTERIZATION OF PERMANENT MURINE HYBRIDOMAS SECRETING MONOCLONAL ANTI‐THY‐1 ANTIBODIES *

    Article • International Journal of Immunogenetics, December 1980, Wiley

    Dr Petr Draber

  111. Identification of TL+ thymocytes with different Lyt phenotypes

    Article • European Journal of Immunology, December 1979, Wiley

    Dr Petr Draber

  112. Cytochalasin B-induced changes in concanavalin A-activated lymphocytes

    Article • Cell and Tissue Research, November 1978, Springer Science + Business Media

    Dr Petr Draber

  113. ROLE OF CELL‐CELL INTERACTIONS IN MITOGENIC STIMULATION OF LYMPHOCYTES: I. DISSOCIATION OF CONCANAVALIN A‐INDUCIBLE LYMPHOCYTE ACTIVATION AND AGGLUTINATION

    Article • International Journal of Immunogenetics, February 1978, Wiley

    Dr Petr Draber