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  1. Structural insights into the interaction of three Y-shaped ligands with PI3Kα
  2. Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3Kα
  3. Nanobodies and chemical cross-links advance the structural and functional analysis of PI3Kα
  4. Cryo-EM structures of PI3Kα reveal conformational changes during inhibition and activation
  5. Isoform-specific activities of the regulatory subunits of phosphatidylinositol 3-kinases – potentially novel therapeutic targets