All Stories

  1. Appropriateness of Term Limits for Administrative Appointments in Pharmacy Programs
  2. C8-guanine mutations in DNA produce a unique DNA conformation that may be involved in cancer
  3. Immobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and Metabolism
  4. Nanoscale electron transport measurements of immobilized cytochrome P450 proteins
  5. Selection of Single-Stranded DNA Molecular Recognition Elements against Exotoxin A Using a Novel Decoy-SELEX Method and Sensitive Detection of Exotoxin A in Human Serum
  6. Single C8-Arylguanine Modifications Render Oligonucleotides in the Z-DNA Conformation under Physiological Conditions
  7. The Use of Immobilized Cytochrome P4502C9 in PMMA-Based Plug Flow Bioreactors for the Production of Drug Metabolites
  8. Measurement of Electron Transfer through Cytochrome P450 Protein on Nanopillars and the Effect of Bound Substrates
  9. A conformational NMR analysis of methymycin aglycones: complete and unambiguous assignments of stereochemically diverse glycosylated methymycin analogs by 1D and 2D NMR techniques and molecular modeling
  10. Src binds cortactin through an SH2 domain cystine-mediated linkage
  11. An investigation into the feasibility of myoglobin-based single-electron transistors
  12. Selective filling of nanowells in nanowell arrays fabricated using polystyrene nanosphere lithography with cytochrome P450 enzymes
  13. Student engagement in professional political advocacy in colleges/schools of pharmacy
  14. Glutathione conjugation of busulfan produces a hydroxyl radical-trapping dehydroalanine metabolite
  15. The conformational effect of para-substituted C8-arylguanine adducts on the B/Z-DNA equilibrium
  16. The Synthesis of C8-Aryl Purines, Nucleosides and Phosphoramidites
  17. A Polymorphic Variant of AFAP-110 Enhances cSrc Activity
  18. A General Synthesis of C8-Arylpurine Phosphoramidites
  19. Electrocatalytic Drug Metabolism by CYP2C9 Bonded to A Self-Assembled Monolayer-Modified Electrode
  20. Differential electronic states observed during A–B DNA duplex conformational transitions
  21. Substrate proton to heme distances in CYP2C9 allelic variants and alterations by the heterotropic activator, dapsone
  22. Use of Simple Docking Methods To Screen a Virtual Library for Heteroactivators of Cytochrome P450 2C9
  23. Synthesis of deuterated naproxens
  24. Preparation, Characterization, and Substrate Metabolism of Gold-Immobilized Cytochrome P450 2C9
  25. Heteroactivator effects on the coupling and spin state equilibrium of CYP2C9
  26. Epoxidation of the methamphetamine pyrolysis product, trans-phenylpropene, to trans-phenylpropylene oxide by CYP enzymes and stereoselective glutathione adduct formation☆
  27. Identification of N,N-dimethylamphetamine formed by methylation of methamphetamine in formalin-fixed liver tissue by multistage mass spectrometry
  28. Actions of a Histone Deacetylase Inhibitor NSC3852 (5-Nitroso-8-quinolinol) Link Reactive Oxygen Species to Cell Differentiation and Apoptosis in MCF-7 Human Mammary Tumor Cells
  29. DNA Cleavage by the Photolysis of Cyclopentadienyl Metal Complexes:  Mechanistic Studies and Sequence Selectivity of Strand Scission by CpW(CO)3CH3
  30. Molecular Dynamics and Free Energy Calculations of the B and Z Forms of C8-Arylguanine Modified Oligonucleotides
  31. CYP2C9 Genotype-Dependent Effects on in Vitro Drug-Drug Interactions: Switching of Benzbromarone Effect from Inhibition to Activation in the CYP2C9.3 Variant
  32. Application of Molecular Dynamics Simulations to Spin-labeled Oligonucleotides
  33. Conversion of Methamphetamine to N-Methyl-Methamphetamine in Formalin Solutions
  34. Effector-Mediated Alteration of Substrate Orientation in Cytochrome P450 2C9†
  35. Synthesis, Properties, and NMR Studies of a C8-Phenylguanine Modified Oligonucleotide that Preferentially Adopts the Z DNA Conformation
  36. Efficient One-Step Suzuki Arylation of Unprotected Halonucleosides, Using Water-Soluble Palladium Catalysts
  37. Intratracheal amiodarone administration to F344 rats directly damages lung airway and parenchymal cells
  38. Synthesis of deuterated 4,4?-diaminodiphenylsulfone (Dapsone) and related analogs
  39. Probing triplex formation by EPR spectroscopy using a newly synthesized spin label for oligonucleotides
  40. Comparison of Magnesium Sulfate and Sodium Sulfate for Removal of Water from Pesticide Extracts of Foods
  41. Solid-phase DNA binding detection by EPR spectroscopy
  42. In Vitro Reaction of Barbiturates with Formaldehyde
  43. Stability of Benzodiazepines in Formaldehyde Solutions
  44. In Vitro Reaction of Formaldehyde with Fenfluramine: Conversion to N-Methyl Fenfluramine
  45. A SHORT PROCEDURE FOR SYNTHESIS OF 4-ETHYNYL-2,2,6,6-TETRAMETHYL-3,4-DEHYDRO-PIPERIDINE-1-OXYL NITROXIDE
  46. Improvement of a Critical Intermediate Step in the Synthesis of a Nitroxide-Based Spin-Labeled Deoxythymidine Analog
  47. Ethanol-Mediated CYP1A1/2 Induction in Rat Skeletal Muscle Tissue
  48. Activation of AP-1 through the MAP Kinase Pathway:  A Potential Mechanism of the Carcinogenic Effect of Arenediazonium Ions
  49. Reactive Oxygen Species in the Aerobic Decomposition of Sodium Hydroxymethanesulfinate
  50. C8-Arylguanine andC8-Aryladenine Formation in Calf Thymus DNA from Arenediazonium Ions
  51. Cobalt-mediated generation of reactive oxygen species and its possible mechanism
  52. Cr(III)-mediated hydroxyl radical generation via Haber-Weiss cycle
  53. Aryl Radical Formation during the Metabolism of Arylhydrazines by Microsomes
  54. Carcinogenesis by the cultivated baked Agaricus bisporus mushroom in mice
  55. 8-Arylguanine adducts from arenediazonium ions and DNA
  56. Cascade Radical Cyclizations via Biradicals Generated from (Z)-1,2,4-Heptatrien-6-ynes
  57. Different Patterns of Mutagenicity of Arenediazonium Ions in V79 Cells and Salmonella typhimurium TA102: Evidence for Different Mechanisms of Action
  58. The use of 2-hydroperoxytetrahydrofuran as a reagent to sequence cytosine and to probe non-Watson-Crick DNA structures
  59. Generation of thiyl and ascorbyl radicals in the reaction of peroxynitrite with thiols and ascorbate at physiological pH
  60. One-electron reduction of vanadate by ascorbate and related free radical generation at physiological pH
  61. Chromate-mediated free radical generation from cysteine, penicillamine, hydrogen peroxide, and lipid hydroperoxides
  62. DNA Sequencing with the Hydroperoxide of Tetrahydrofuran
  63. Reaction of Cr(VI) with ascorbate and hydrogen peroxide generates hydroxyl radicals and causes DNA damage: role of a Cr(IV)-mediated Fenton-like reaction
  64. Agaricus Bisporus: An assessment of its carcinogenic potency
  65. Base pairing of 8-oxoguanosine and 8-oxo-2'-deoxyguanosine with 2'-deoxyadenosine, 2'-deoxycytosine, 2'-deoxyguanosine, and thymidine
  66. An Improved Synthesis of 8-Bromo-2′-deoxyguanosine
  67. DNA alkyation and mutagenicity of related hydroxypropylating and methylating agents in V79 cells
  68. Deferoxamine inhibition of Cr(V)-mediated radical generation and deoxyguanine hydroxylation: ESR and HPLC evidence
  69. Tumor induction with hexanal methylformylhydrazone of Gyromitra esculenta
  70. N-Nitrosoatrazine: synthesis, kinetics of formation, and nuclear magnetic resonance spectra and other properties
  71. 8-Hydroxy-2′-deoxyguanosine formation during the catalytic oxidation of hydrazines in the presence of 2′-deoxyguanosine
  72. Chemical oxidation and metabolism of N-methyl-N-formylhydrazine. Evidence for diazenium and radical intermediates
  73. The mechanism of inhibition of cytochrome P450IIE1 by dihydrocapsaicin
  74. The mutagenicity of capsaicin and dihydrocapsaicin in V79 cells
  75. Capsaicinoids: their separation, synthesis, and mutagenicity [Erratum to document cited in CA108(13):112057d]
  76. Capsaicinoids: their separation, synthesis, and mutagenicity
  77. Hydrazines and diazonium ions of mushroom origin and cancer
  78. Anomalous reaction of adenine and 4-(hydroxymethyl)benzenediazonium ion
  79. Synthesis of the proposed penultimate biosynthetic triene intermediate of monensin A
  80. Synthesis of the putative biosynthetic triene precursor of Monensin A
  81. Comparison of free energy changes for nitrogen inversion and electron loss for some amino nitrogen compounds
  82. Electron loss from 1,3,3-trimethyl-2-azabicyclo[2.2.2]octane derivatives. Is .sigma.-coupling thermodynamically important?
  83. One-electron oxidation of trialkylsulfenamides
  84. The 3,3-dimethyl-2-azabicyclo[2.2.2]octyl system as a Bredt's rule kinetically stabilized dialkylamino group in electron-transfer studies
  85. 6-Methyl-1,6-diazabicyclo[6.2.2]dodecane: an inside, outside six-atom bridged boat piperidine
  86. Conformational interconversions in pentaalkylhydrazine cation tetrafluoroborates
  87. Nitrosohydrazine conformations. The effect of replacing C(1)-H of 2-nitroso-2-azabicyclo[2.2.2]octane derivatives by nitrogen