Professor Peixuan Guo

3D RNA nanocage for encapsulation and shielding of hydrophobic biomolecules to improve ...

• Nano Research
• September 2020

Construction of RNA nanotubes

• Nano Research
• July 2019

Photo-controlled release of paclitaxel and model drugs from RNA pyramids

• Nano Research
• September 2018

RNA versatility, flexibility, and thermostability for practice in RNA nanotechnology an...

• Wiley Interdisciplinary Reviews - RNA
• November 2017

An Arginine Finger Regulates the Sequential Action of Asymmetrical Hexameric ATPase in ...

• Molecular and Cellular Biology
• July 2016

Precise spatial control of cavitation erosion in a vessel phantom by using an ultrasoni...

• Ultrasonics Sonochemistry
• July 2016

Development of Potent Antiviral Drugs Inspired by Viral Hexameric DNA-Packaging Motors ...

• Journal of Virology
• June 2016

Controllable self-assembly of RNA dendrimers

• Nanomedicine Nanotechnology Biology and Medicine
• April 2016

Biological Nanomotors with a Revolution, Linear, or Rotation Motion Mechanism

• Microbiology and Molecular Biology Reviews
• January 2016

Systemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utiliz...

• ACS Nano
• October 2015

RNA as a stable polymer to build controllable and defined nanostructures for material a...

• Nano Today
• October 2015

Discovery of a new method for potent drug development using power function of stoichiom...

• Expert Opinion on Drug Delivery
• August 2015

Methods in Molecular Biology 1297: RNA Nanotechnology and Therapeutics: Methods and Pro...

• ChemBioChem
• August 2015

RNA Nanoparticles Derived from Three-Way Junction of Phi29 Motor pRNA Are Resistant to ...

• Nucleic Acid Therapeutics
• August 2015

Construction of RNA–Quantum Dot Chimera for Nanoscale Resistive Biomemory Application

• ACS Nano
• July 2015

Regression of Gastric Cancer by Systemic Injection of RNA Nanoparticles Carrying both L...

• Scientific Reports
• July 2015

New approach to develop ultra-high inhibitory drug using the power function of the stoi...

• Nanomedicine
• July 2015

RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model

• Oncotarget
• June 2015

Single pore translocation of folded, double-stranded, and tetra-stranded DNA through ch...

• Biomaterials
• June 2015

Probing surface hydrophobicity of individual protein at single-molecule resolution usin...

• Science China Materials
• June 2015

Delivery of RNA Nanoparticles into Colorectal Cancer Metastases Following Systemic Admi...

• ACS Nano
• February 2015

RNA Nanotechnology and Therapeutics

• January 2015

Studies and application of Nanomotor for Single Pore Sensing, Single Fluorescence Imagi...

• Biochemistry & Analytical Biochemistry
• January 2015

Overview of Methods in RNA Nanotechnology: Synthesis, Purification, and Characterizatio...

• January 2015

Methods and Assays for Specific Targeting and Delivery of RNA Nanoparticles to Cancer M...

• January 2015

Large Scale Purification of RNA Nanoparticles by Preparative Ultracentrifugation

• January 2015

Simple Method for Constructing RNA Triangle, Square, Pentagon by Tuning Interior RNA 3W...

• January 2015

Functional Assays for Specific Targeting and Delivery of RNA Nanoparticles to Brain Tumor

• January 2015

Using RNA Nanoparticles with Thermostable Motifs and Fluorogenic Modules for Real-Time ...

• January 2015

Binomial distribution for quantification of protein subunits in biological Nanoassembli...

• Nanomedicine Nanotechnology Biology and Medicine
• October 2014

Physicochemically Tunable Polyfunctionalized RNA Square Architecture with Fluorogenic a...

• ACS Nano
• August 2014

Common mechanisms of DNA translocation motors in bacteria and viruses using one-way rev...

• Biotechnology Advances
• July 2014

RNA as a Boiling-Resistant Anionic Polymer Material To Build Robust Structures with Def...

• ACS Nano
• May 2014

Single molecule photobleaching (SMPB) technology for counting of RNA, DNA, protein and ...

• Methods
• May 2014

Biophysical Studies Reveal New Evidence for One-Way Revolution Mechanism of Bacteriopha...

• Biophysical Journal
• May 2014

Entropy-Driven One-Step Formation of Phi29 pRNA 3WJ from Three RNA Fragments

• Biochemistry
• April 2014

Stable RNA nanoparticles as potential new generation drugs for cancer therapy

• Advanced Drug Delivery Reviews
• February 2014

Two classes of nucleic acid translocation motors: rotation and revolution without rotation

• Cell & Bioscience
• January 2014

Finding of widespread viral and bacterial revolution dsDNA translocation motors distinc...

• Cell & Bioscience
• January 2014

Ocular Delivery of pRNA Nanoparticles: Distribution and Clearance After Subconjunctival...

• Pharmaceutical Research
• December 2013

Engineered Nanopore of Phi29 DNA-Packaging Motor for Real-Time Detection of Single Colo...

• ACS Nano
• November 2013

Discovery of a new motion mechanism of biomotors similar to the earth revolving around ...

• Virology
• November 2013

The ATPase of the phi29 DNA packaging motor is a member of the hexameric AAA+ superfamily

• Virology
• August 2013

Revolution rather than rotation of AAA+ hexameric phi29 nanomotor for viral dsDNA packa...

• Virology
• August 2013

Fabrication of pRNA nanoparticles to deliver therapeutic RNAs and bioactive compounds i...

• Nature Protocols
• August 2013

Ultrastable pRNA hexameric ring gearing hexameric phi29 DNA-packaging motor by revolvin...

• Current Opinion in Biotechnology
• August 2013

RNA Nanotechnology and Therapeutics

• July 2013

Conference Scene: Advances in RNA nanotechnology promise to transform medicine

• Nanomedicine
• July 2013

Toward Reproducible Computational Research: An Empirical Analysis of Data and Code Poli...

• PLoS ONE
• June 2013

RNA Junction Motifs as Scaffolds for Construction of Multifunctional RNA Nanoparticles

• June 2013

Single-Molecule Approach to Study RNA Nanoparticles

• June 2013

Design and Construction of RNA Nanoparticles Targeting Prostate Cancer

• June 2013

Uniqueness, Advantages, Challenges, Solutions, and Perspectives in Therapeutics Applyin...

• June 2013

Fabrication Methods for RNA Nanoparticle Assembly Based on Bacteriophage phi29 Packagin...

• June 2013

Thermodynamically Stable RNA Three-Way Junction for Constructing Multifunctional Nanopa...

• June 2013

Conjugation of RNA Aptamer to RNA Nanoparticles for Targeted Drug Delivery

• June 2013

Mechanism of One-Way Traffic of Hexameric Phi29 DNA Packaging Motor with Four Electropo...

• ACS Nano
• May 2013

Synthesis and Biological Evaluation of Novel Folic Acid Receptor-Targeted, β-Cyclodextr...

• PLoS ONE
• May 2013

Tu1890 Targeting Colorectal Cancer Liver Metastases With Folate-Conjugated Ultrastable ...

• Gastroenterology
• May 2013

Channel Size Conversion of Phi29 DNA-Packaging Nanomotor for Discrimination of Single- ...

• ACS Nano
• April 2013

Solid-state and biological nanopore for real-time sensing of single chemical and sequen...

• Nano Today
• February 2013

Incorporation of a viral DNA-packaging motor channel in lipid bilayers for real-time, s...

• Nature Protocols
• January 2013

Push Through One-Way Valve Mechanism of Viral DNA Packaging Nanomotor

• January 2013

Rolling Circle Transcription of Tandem siRNA to Generate Spherulitic RNA Nanoparticles ...

• Molecular Therapy — Nucleic Acids
• August 2012

Ultrastable synergistic tetravalent RNA nanoparticles for targeting to cancers

• Nano Today
• August 2012

Formation of lipid bilayers inside microfluidic channel array for monitoring membrane-e...

• Biomedical Microdevices
• July 2012

Real-Time Sensing and Discrimination of Single Chemicals Using the Channel of Phi29 DNA...

• ACS Nano
• April 2012

Role of Channel Lysines and the “Push Through a One-Way Valve” Mechanism of the Viral D...

• Biophysical Journal
• January 2012

Synthesis, Conjugation, and Labeling of Multifunctional pRNA Nanoparticles for Specific...

• January 2012

“Push Through One-Way Valve” Mechanism of Viral DNA Packaging

• January 2012

Three reversible and controllable discrete steps of channel gating of a viral DNA packa...

• Biomaterials
• November 2011

Thermodynamically stable RNA three-way junction for constructing multifunctional nanopa...

• Nature Physics
• September 2011

RNA Nanotechnology: Methods for synthesis, conjugation, assembly and application of RNA...

• Methods
• June 2011

Optimized method for the synthesis and purification of adenosine – Folic acid conjugate...

• Methods
• June 2011

Assembly of multifunctional phi29 pRNA nanoparticles for specific delivery of siRNA and...

• Methods
• June 2011

Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer fo...

• Methods
• June 2011

A Boost for the Emerging Field of RNA Nanotechnology

• ACS Nano
• May 2011

Assembly of Therapeutic pRNA-siRNA Nanoparticles Using Bipartite Approach

• Molecular Therapy
• April 2011

Pharmacological Characterization of Chemically Synthesized Monomeric phi29 pRNA Nanopar...

• Molecular Therapy
• April 2011

Fabrication of Stable and RNase-Resistant RNA Nanoparticles Active in Gearing the Nanom...

• ACS Nano
• January 2011

Membrane-Embedded Channel of Bacteriophage Phi29 DNA-Packaging Motor for Translocation ...

• January 2011

Self-Assembly of Heptameric Nanoparticles Derived from Tag-Functionalized Phi29 Connectors

• ACS Nano
• December 2010

Dual-Channel Single-Molecule Fluorescence Resonance Energy Transfer to Establish Distan...

• ACS Nano
• November 2010

The emerging field of RNA nanotechnology

• Nature Physics
• November 2010

Application of Phi29 Motor pRNA for Targeted Therapeutic Delivery of siRNA Silencing Me...

• Molecular Therapy
• November 2010

One-Way Traffic of a Viral Motor Channel for Double-Stranded DNA Translocation

• Nano Letters
• September 2010

Assembly Mechanism of the Sixty-Subunit Nanoparticles via Interaction of RNA with the ...

• ACS Nano
• June 2010

AIDS Treatment with Novel Anti-HIV Compounds Improved by Nanotechnology

• The AAPS Journal
• April 2010

Engineering RNA for Targeted siRNA Delivery and Medical Application

• Advanced Drug Delivery Reviews
• April 2010

Design and application of single fluorophore dual-view imaging system containing both t...

• February 2010

Robust properties of membrane-embedded connector channel of bacterial virus phi29 DNA p...

• Molecular BioSystems
• January 2010

Engineering of the Fluorescent-Energy-Conversion Arm of Phi29 DNA Packaging Motor for S...

• Small
• November 2009

Construction of a laser combiner for dual fluorescent single molecule imaging of pRNA o...

• Biomedical Microdevices
• October 2009

Translocation of double-stranded DNA through membrane-adapted phi29 motor protein nanop...

• Nature Physics
• September 2009

Targeted delivery of anti-coxsackievirus siRNAs using ligand-conjugated packaging RNAs

• Antiviral Research
• September 2009

Adjustable Ellipsoid Nanoparticles Assembled from Re-engineered Connectors of the Bacte...

• ACS Nano
• August 2009

Construction of Bacteriophage Phi29 DNA Packaging Motor and its Applications in Nanotec...

• Annals of Biomedical Engineering
• June 2009

Fabrication of polyvalent therapeutic RNA nanoparticles for specific delivery of siRNA,...

• April 2009

Approaches for stoichiometry and distance determination of nanometer bio-complex by dua...

• April 2009

Fabrication of Massive Sheets of Single Layer Patterned Arrays Using Lipid Directed Ree...

• ACS Nano
• January 2009

Evaluation of specific delivery of chimeric phi29 pRNA/siRNA nanoparticles to multiple ...

• Molecular BioSystems
• January 2009

Reversible Switching of pRNA Activity on the DNA Packaging Motor of Bacteriophage phi29

• Journal of the American Chemical Society
• December 2008

Bright-field analysis of phi29 DNA packaging motor using a magnetomechanical system

• Applied Physics Letters
• October 2008

Strand and nucleotide-dependent ATPase activity of gp16 of bacterial virus phi29 DNA pa...

• Virology
• October 2008

Capture and alignment of phi29 viral particles in sub-40 nanometer porous alumina membr...

• Biomedical Microdevices
• September 2008

Modular assembly of chimeric phi29 packaging RNAs that support DNA packaging

• Biochemical and Biophysical Research Communications
• August 2008

The effect of N- or C-terminal alterations of the connector of bacteriophage phi29 DNA ...

• Nanomedicine Nanotechnology Biology and Medicine
• March 2008

From bench to bedside: successful translational nanomedicine

• Nanomedicine Nanotechnology Biology and Medicine
• December 2007

Grouping of Ferritin and Gold Nanoparticles Conjugated to pRNA of the Phage phi29 DNA-P...

• Journal of Nanoscience and Nanotechnology
• September 2007

Crystallization of Phi29 Spindle-Shaped Nano-Bar Anti-Receptor with Glycosidase Domain

• Journal of Nanoscience and Nanotechnology
• August 2007

Phi29 pRNA vector for efficient escort of hammerhead ribozyme targeting survivin in mul...

• Cancer Biology & Therapy
• May 2007

Viral nanomotors for packaging of dsDNA and dsRNA

• Molecular Microbiology
• May 2007

Counting of six pRNAs of phi29 DNA-packaging motor with customized single-molecule dual...

• The EMBO Journal
• January 2007

Interaction of gp16 with pRNA and DNA for Genome Packaging by the Motor of Bacterial Vi...

• Journal of Molecular Biology
• February 2006

RNA Nanotechnology: Engineering, Assembly and Applications in Detection, Gene Delivery ...

• Journal of Nanoscience and Nanotechnology
• December 2005

<I>A Special Issue on</I> Bionanotechnology

• Journal of Nanoscience and Nanotechnology
• December 2005

Specific Delivery of Therapeutic RNAs to Cancer Cells via the Dimerization Mechanism of...

• Human Gene Therapy
• September 2005

Controllable Self-Assembly of Nanoparticles for Specific Delivery of Multiple Therapeut...

• Nano Letters
• September 2005

Translocation of Nicked but not Gapped DNA by the Packaging Motor of Bacteriophage phi29

• Journal of Molecular Biology
• August 2005

Quantum dots for robust and simple assays using single particles in nanodevices

• Nanomedicine Nanotechnology Biology and Medicine
• June 2005

Construction and 3-D Computer Modeling of Connector Arrays with Tetragonal to Decagonal...

• Journal of Nanoscience and Nanotechnology
• June 2005

Bottom-up Assembly of RNA Arrays and Superstructures as Potential Parts in Nanotechnology

• Nano Letters
• September 2004

A simple mathematical formula for stoichiometry quantification of viral and nanobiologi...

• Journal of Virological Methods
• January 2004

Gene cloning, purification, and stoichiometry quantification of phi29 anti-receptor gp1...

• Gene
• October 2003

Use of acetone to attain highly active and soluble DNA packaging protein Gp16 of Phi29 ...

• Virology
• August 2003

Construction of phi29 DNA-Packaging RNA Monomers, Dimers, and Trimers with Variable Siz...

• Journal of Nanoscience and Nanotechnology
• August 2003

Use of PEG to acquire highly soluble DNA-packaging enzyme gp16 of bacterial virus phi29...

• Journal of Virological Methods
• May 2003

Only one pRNA hexamer but multiple copies of the DNA-packaging protein gp16 are needed ...

• Virology
• April 2003

Structure and function of φ29 hexameric RNA that drives the viral DNA packaging motor: ...

• January 2002

Chemical Modification Patterns of Active and Inactive as Well as Procapsid-Bound and Un...

• Virology
• March 2001

Probing the structure of monomers and dimers of the bacterial virus phi29 hexamer RNA c...

• RNA
• September 2000

Photoinduced cross-linking of RNA by cis-Rh(phen)2Cl2+ and cis-Rh(phen)(phi)Cl2+: A new...

• Bioorganic & Medicinal Chemistry Letters
• June 1999

Sequence requirement for hand-in-hand interaction in formation of RNA dimers and hexame...

• RNA
• June 1999

Inter-RNA Interaction of Phage φ29 pRNA to Form a Hexameric Complex for Viral DNA Trans...

• Molecular Cell
• July 1998

Inhibition of Phage φ29 Assembly by Antisense Oligonucleotides Targeting Viral pRNA Ess...

• Virology
• August 1995

Circularly Permuted Viral pRNA Active and Specific in the Packaging of Bacteriophage φ2...

• Virology
• March 1995

Differential diagnosis of infectious laryngotracheitis from other avian respiratory dis...

• Journal of Virological Methods
• December 1994

Construction of Recombinant Avian Infectious Laryngotracheitis Virus Expressing the β-G...

• Virology
• August 1994

A Highly Sensitive System for the in Vitro Assembly of Bacteriophage (ø29 of Bacillus s...

• Virology
• August 1994

The Proximate 5′ and 3′ Ends of the 120-Base Viral RNA (pRNA) Are Crucial for the Packa...

• Virology
• May 1994

Introduction: Principles, perspectives and potential applications in viral assembly

• Seminars in Virology
• February 1994

Biological and biochemical properties of the small viral RNA(pRNA) essential for the pa...

• Seminars in Virology
• February 1994

Transactivation of the early SV40 promoter by avian infectious laryngotracheitis virus ...

• Journal of Virological Methods
• December 1993

An avian hepatoma cell line for the cultivation of infectious laryngotracheitis virus a...

• Journal of Virological Methods
• August 1993

sRNA of phage φ29 of Bacillus subtilis mediates DNA packaging of φ29 proheads assembled...

• Virology
• November 1991

Regulation of the phage φ29 prohead shape and size by the portal vertex

• Virology
• July 1991

Characterization of the gene and an antigenic determinant of equine herpesvirus type-1 ...

• Gene
• March 1990

Prohead and DNA-gp3-dependent ATPase activity of the DNA packaging protein gp16 of bact...

• Journal of Molecular Biology
• September 1987

Initiation events in in-vitro packaging of bacteriophage φ29 DNA-gp3

• Journal of Molecular Biology
• September 1987

A small viral RNA is required for in vitro packaging of bacteriophage phi 29 DNA

• Science
• May 1987

Characterization of the small RNA of the bacteriophage ø29 DNA packaging machine

• Nucleic Acids Research
• January 1987

Bacterial Virus f29 DNA-Packaging Motor and Its Potential Applications in Gene Therapy ...