All Stories

  1. Hidden Activities of Tyrosine Phenol-Lyase and Tryptophan Indole-Lyase: Recombinant PLP-Dependent C–C Lyases as New Biocatalysts for Antimicrobial Thiosulfinate Generation

    Article • Pharmaceuticals, February 2026, MDPI AG

    Dr. Pavel N. Solyev

  2. Cycloaddition of benzo[ d ]thiazoles with imidazol-4-one-activated donor–acceptor cyclopropanes: synthesis of spirocyclic inhibitors of HIV-1

    Article • Organic & Biomolecular Chemistry, January 2026, Royal Society of Chemistry

    Dr. Pavel N. Solyev

  3. Stereoselective synthesis of functionalized perhydropyrrolo[1,2- b ]isoxazoles based on (3 + 2)-annulation of donor–acceptor cyclopropanes and isoxazolines

    Article • Organic & Biomolecular Chemistry, January 2026, Royal Society of Chemistry

    Dr. Pavel N. Solyev

  4. Rapid and Efficient Radiolabeling of Short Peptides

    Article • ACS Omega, September 2025, American Chemical Society (ACS)

    Dr. Pavel N. Solyev

  5. Thymidine-Inosine Dimer Building Block for Reversible Modification of Synthetic Oligonucleotides

    Article • Molecules, September 2025, MDPI AG

    Dr. Pavel N. Solyev

  6. Anti-HIV and Antimicrobial Activity of 7-Hydrazino-8-hydroxyquinoline-Based Aromatic Hydrazones

    Article • International Journal of Molecular Sciences, August 2025, MDPI AG

    Dr. Pavel N. Solyev

  7. Synthesis of Chroman Derivatives by Group Transposition and Atom Swapping in 1‐Tetralones: Single‐Atom Editing Enabled by Oxidative Ring Contraction of Benzoxepine Silyl Ketene Acetals

    Article • Angewandte Chemie, May 2025, Wiley

    Dr. Pavel N. Solyev

  8. Redesigning methionine γ-lyase for improved stability and catalytic activity in the β-elimination reaction for the synthesis of thiosulfinates

    Article • Biochimie, May 2025, Elsevier

    Dr. Pavel N. Solyev

  9. Piperazine-Substituted Pyranopyridines Exhibit Antiproliferative Activity and Act as Inhibitors of HBV Virion Production

    Article • International Journal of Molecular Sciences, April 2025, MDPI AG

    Dr. Pavel N. Solyev

  10. Distinct N6-Substituted Adenosine Derivatives Exhibit Receptor-Specific Anticytokinin Action by Unknown Non-competitive Mechanism

    Article • Journal of Plant Growth Regulation, April 2025, Springer Science + Business Media

    Dr. Pavel N. Solyev

  11. Improved Synthesis of Effective 3-(Indolin-6-yl)-4-(N-pyrazole-sulfonamide)-1H-pyrrolo[2,3-b]pyridine-Based Inhibitors of NADPH Oxidase 2

    Article • International Journal of Molecular Sciences, April 2025, MDPI AG

    Dr. Pavel N. Solyev

  12. Revealing O-acetylhomoserine sulfhydrylase involved in direct sulfhydrylation pathway in Clostridium tetani

    Article • Biochimie, April 2025, Elsevier

    Dr. Pavel N. Solyev

  13. 6-Bromoindole- and 6-Bromoindazole-Based Inhibitors of Bacterial Cystathionine γ-Lyase Containing 3-Aminothiophene-2-Carboxylate Moiety

    Article • Molecules, January 2025, MDPI AG

    Dr. Pavel N. Solyev

  14. Synthesis of daidzein derivatives for targeted drug delivery

    Article • Mendeleev Communications, January 2025, OOO Zhurnal "Mendeleevskie Soobshcheniya"

    Dr. Pavel N. Solyev

  15. Development of a New Inhibitor of Bacterial Cystathionine γ-Lyase Based on 6-Bromoindole and Aminothiophene

    Article • Molecular Biology, December 2024, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  16. Synthesis and Antimicrobial Activity of Thiosulfinates and Allicin Analogues

    Article • Molecular Biology, December 2024, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  17. Toxicity Study of the Pharmacological Pair of Encapsulated Citrobacter freundii C115H Methionine γ-Lyase/Methiin

    Article • Molecular Biology, December 2024, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  18. Bacterial Purine Nucleoside Phosphorylases from Mesophilic and Thermophilic Sources: Characterization of Their Interaction with Natural Nucleosides and Modified Arabinofuranoside Analogues

    Article • Biomolecules, August 2024, MDPI AG

    Dr. Pavel N. Solyev

  19. Synthesis of Isoquinoline‐Containing 5,6‐Dicyano‐2,1,3‐Benzothiadiazoles: Unusual Heterocyclization into Dibenzo‐1,6‐Naphthyridine Framework

    Article • Asian Journal of Organic Chemistry, August 2024, Wiley

    Dr. Pavel N. Solyev

  20. O-Acetylhomoserine Sulfhydrylase As a Key Enzyme of Direct Sulfhydrylation in Microbial Methionine Biosynthesis (A Review)

    Article • Applied Biochemistry and Microbiology, May 2024, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  21. A convenient synthesis of a chlorobenzothiophenyl-indole-based inhibitor of bacterial cystathionine γ-lyase

    Article • Mendeleev Communications, March 2024, OOO Zhurnal "Mendeleevskie Soobshcheniya"

    Dr. Pavel N. Solyev

  22. Synthesis of Spiro[imidazole‐4,3′‐pyrrolo[1,2‐a]quinolin]‐ 5‐ones via 1,3‐Dipolar Cycloaddition of Quinolinium Ylides with Arylydeneimidazol‐4‐ones

    Article • ChemistrySelect, February 2024, Wiley

    Dr. Pavel N. Solyev

  23. Novel Hydroxamic Acids Containing Aryl-Substituted 1,2,4- or 1,3,4-Oxadiazole Backbones and an Investigation of Their Antibiotic Potentiation Activity

    Article • International Journal of Molecular Sciences, December 2023, MDPI AG

    Dr. Pavel N. Solyev

  24. Anticandidal Activity of In Situ Methionine γ-Lyase-Based Thiosulfinate Generation System vs. Synthetic Thiosulfinates

    Article • Pharmaceuticals, December 2023, MDPI AG

    Dr. Pavel N. Solyev

  25. 5-Alkyloxymethyl Derivatives of 2ʹ-Deoxyuridine Bearing 2,4-Dinitrophenyl and Dansyl Groups: Synthesis and Antibacterial Activity

    Article • Russian Journal of Bioorganic Chemistry, December 2023, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  26. Examination of Diels–Alder/Tsuji–Trost Route towards Kopsia Alkaloids

    Article • Synthesis, October 2023, Thieme Publishing Group

    Dr. Pavel N. Solyev

  27. 5‐Substituted Uridines with Activity against Gram‐Positive Bacteria

    Article • ChemMedChem, October 2023, Wiley

    Dr. Pavel N. Solyev

  28. Thiosulfinates: Cytotoxic and Antitumor Activity

    Article • Biochemistry (Moscow), July 2023, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  29. Merging Johnson–Claisen and Aromatic Claisen [3,3]-Sigmatropic Rearrangements: Ytterbium Triflate/2,6-Di-tert-butylpyridine Catalytic System

    Article • The Journal of Organic Chemistry, June 2023, American Chemical Society (ACS)

    Dr. Pavel N. Solyev

  30. Antibacterial Conjugates of Kanamycin A with Vancomycin and Eremomycin: Biological Activity and a New MS-Fragmentation Pattern of Cbz-Protected Amines

    Article • Antibiotics, May 2023, MDPI AG

    Dr. Pavel N. Solyev

  31. Synthesis of the Indole-Based Inhibitors of Bacterial Cystathionine γ-Lyase NL1-NL3

    Article • Molecules, April 2023, MDPI AG

    Dr. Pavel N. Solyev

  32. Synthesis of Cy5-Labelled C5-Alkynyl-modified cytidine triphosphates via Sonogashira coupling for DNA labelling

    Article • Bioorganic Chemistry, February 2023, Elsevier

    Dr. Pavel N. Solyev

  33. Synthetic Optimizations for Gram-Scale Preparation of 1-O-Methyl d-Glycero-α-d-gluco-heptoside 7-Phosphate from d-Glucose

    Article • Molecules, November 2022, MDPI AG

    Dr. Pavel N. Solyev

  34. HFIP‐Mediated CH Functionalization

    Article • October 2022, Wiley

    Dr. Pavel N. Solyev

  35. Oligoglycol carbonate prodrugs of 5-modified 2'-deoxyuridines: synthesis and antibacterial activity

    Article • Mendeleev Communications, July 2022, OOO Zhurnal "Mendeleevskie Soobshcheniya"

    Dr. Pavel N. Solyev

  36. Comparative analysis of the white rot fungus Trametes hirsuta 072 laccases ability to modify 17β-oestradiol in the aqueous medium

    Article • Biocatalysis and Biotransformation, June 2022, Taylor & Francis

    Dr. Pavel N. Solyev

  37. Synthesis of α‐D‐Ribose 1‐Phosphate and 2‐Deoxy‐α‐D‐Ribose 1‐Phosphate Via Enzymatic Phosphorolysis of 7‐Methylguanosine and 7‐Methyldeoxyguanosine

    Article • Current Protocols, January 2022, Wiley

    Dr. Pavel N. Solyev

  38. 3′-Amino modifications enhance the antifungal properties of N4-alkyl-5-methylcytidines for potential biocides

    Article • New Journal of Chemistry, January 2022, Royal Society of Chemistry

    Dr. Pavel N. Solyev

  39. Total Synthesis of Elmenols A and B and Related Rearranged Angucyclinones

    Article • ChemistrySelect, November 2021, Wiley

    Dr. Pavel N. Solyev

  40. 1,5-Hydride-Shift-Triggered Cyclization for the Synthesis of Unsymmetric Julolidines

    Article • Synthesis, July 2021, Thieme Publishing Group

    Dr. Pavel N. Solyev

  41. Discovery of novel N4-alkylcytidines as promising antimicrobial agents

    Article • European Journal of Medicinal Chemistry, April 2021, Elsevier

    Dr. Pavel N. Solyev

  42. Synthesis and Aerobic Dehydrogenation of Indolizin-1-ol Derivatives

    Article • The Journal of Organic Chemistry, February 2021, American Chemical Society (ACS)

    Dr. Pavel N. Solyev

  43. Glycol and Phosphate Depot Forms of 4- and/or 5-Modified Nucleosides Exhibiting Antibacterial Activity

    Article • Molecular Biology, January 2021, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  44. Disclosing biosynthetic connections and functions of atypical angucyclinones with a fragmented C-ring

    Article • Natural Product Reports, January 2021, Royal Society of Chemistry

    Dr. Pavel N. Solyev

  45. Three-Component Reaction of 3,3-Difluorocyclopropenes, s-Tetrazines, and (benzo) Pyridines

    Article • The Journal of Organic Chemistry, December 2020, American Chemical Society (ACS)

    Dr. Pavel N. Solyev

  46. Construction of siloxane structures with P-Tolyl substituents at the silicon atom

    Article • Journal of Organometallic Chemistry, November 2020, Elsevier

    Dr. Pavel N. Solyev

  47. Direct Reductive Amination of Camphor Using Iron Pentacarbonyl as Stoichiometric Reducing Agent: Features and Limitations

    Article • European Journal of Organic Chemistry, October 2020, Wiley

    Dr. Pavel N. Solyev

  48. Imidazolone-activated donor-acceptor cyclopropanes with a peripheral stereocenter. A study on stereoselectivity of cycloaddition with aldehydes

    Article • Chemistry of Heterocyclic Compounds, August 2020, Springer Science + Business Media

    Dr. Pavel N. Solyev

  49. Construction of the Heterologous Laccase Producer Aspergillus nidulans lac№4 (argB–) and Its Application for the Progesterone Transformation

    Article • Applied Biochemistry and Microbiology, May 2020, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  50. Imidazol-5-one as an Acceptor in Donor–Acceptor Cyclopropanes: Cycloaddition with Aldehydes

    Article • Organic Letters, March 2020, American Chemical Society (ACS)

    Dr. Pavel N. Solyev

  51. 5-Alkylthiomethyl Derivatives of 2'-Deoxyuridine: Synthesis and Antibacterial Activity

    Article • Russian Journal of Bioorganic Chemistry, March 2020, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  52. Synthesis of water-soluble prodrugs of 5-modified 2ʹ-deoxyuridines and their antibacterial activity

    Article • The Journal of Antibiotics, January 2020, Springer Science + Business Media

    Dr. Pavel N. Solyev

  53. (3+2) Cycloaddition of N-benzylazomethine methylide with 4-arylidene-1H-imidazol-5(4H)-ones

    Article • Chemistry of Heterocyclic Compounds, January 2020, Springer Science + Business Media

    Dr. Pavel N. Solyev

  54. Structural isomers of cinnamic hydroxamic acids block HCV replication via different mechanisms

    Article • European Journal of Medicinal Chemistry, December 2019, Elsevier

    Dr. Pavel N. Solyev

  55. Enzymatic Synthesis of 2-Deoxyribose 1-Phosphate and Ribose 1 Phosphate and Subsequent Preparation of Nucleosides

    Article • European Journal of Organic Chemistry, October 2019, Wiley

    Dr. Pavel N. Solyev

  56. Investigation of 5’-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents

    Article • Molecules, September 2019, MDPI AG

    Dr. Pavel N. Solyev

  57. Biotransformation of progesterone by Aspergillus nidulans VKPM F-1069 (wild type)

    Article • Steroids, September 2019, Elsevier

    Dr. Pavel N. Solyev

  58. Structure-activity studies of irumamycin type macrolides from Streptomyces sp. INA-Ac-5812

    Article • Tetrahedron Letters, May 2019, Elsevier

    Dr. Pavel N. Solyev

  59. Novel 5-substituted derivatives of 2’-deoxy-6-azauridine with antibacterial activity

    Article • The Journal of Antibiotics, February 2019, Springer Science + Business Media

    Dr. Pavel N. Solyev

  60. Aerobic Co-/N-Hydroxysuccinimide-Catalyzed Oxidation of p-Tolylsiloxanes to p-Carboxyphenylsiloxanes: Synthesis of Functionalized Siloxanes as Promising Building Blocks for Siloxane-Based Materials

    Article • Journal of the American Chemical Society, January 2019, American Chemical Society (ACS)

    Dr. Pavel N. Solyev

  61. Hydrazo coupling: the efficient transition-metal-free C–H functionalization of 8-hydroxyquinoline and phenol through base catalysis

    Article • Green Chemistry, January 2019, Royal Society of Chemistry

    Dr. Pavel N. Solyev

  62. Novel 5′-Norcarbocyclic Pyrimidine Derivatives as Antibacterial Agents

    Article • Molecules, November 2018, MDPI AG

    Dr. Pavel N. Solyev

  63. Novel 5′-Norcarbocyclic Derivatives of Bicyclic Pyrrolo- and Furano[2,3-d]Pyrimidine Nucleosides

    Article • Molecules, October 2018, MDPI AG

    Dr. Pavel N. Solyev

  64. Synthesis of Cytokinins via Enzymatic Arsenolysis of Purine Nucleosides

    Article • Current Protocols in Nucleic Acid Chemistry, October 2018, Wiley

    Dr. Pavel N. Solyev

  65. Conjugates of 17-substituted testosterone and epitestosterone with pyropheophorbide a differing in the length of linkers

    Article • Steroids, October 2018, Elsevier

    Dr. Pavel N. Solyev

  66. 4-Chloro-l-kynurenine as fluorescent amino acid in natural peptides

    Article • Amino Acids, September 2018, Springer Science + Business Media

    Dr. Pavel N. Solyev

  67. One-step irreversible and efficient chemoenzymatic cleavage of ribose for preparation of nucleobases

    Article • Organic & Biomolecular Chemistry, January 2018, Royal Society of Chemistry

    Dr. Pavel N. Solyev, Dr Konstantin Michailovich Polyakov

  68. Biotransformation of progesterone by the ascomycete Aspergillus niger N402

    Article • Biochemistry (Moscow), January 2018, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  69. Aerobic Co or Cu/NHPI-catalyzed oxidation of hydride siloxanes: synthesis of siloxanols

    Article • Green Chemistry, January 2018, Royal Society of Chemistry

    Dr. Pavel N. Solyev

  70. Crystallomycin revisited after 60 years: aspartocins B and C

    Article • MedChemComm, January 2018, Royal Society of Chemistry

    Dr. Pavel N. Solyev

  71. Synthesis of a New Imidazo[4′,5′:3,4]pyrazolo[5,1-c ][1,2,4]triazine-4,8-dione Heterocyclic System

    Article • Journal of Heterocyclic Chemistry, December 2017, Wiley

    Dr. Pavel N. Solyev

  72. Modulation of Cell Death Pathways by Hepatitis C Virus Proteins in Huh7.5 Hepatoma Cells

    Article • International Journal of Molecular Sciences, November 2017, MDPI AG

    Dr. Pavel N. Solyev

  73. New benzophenone phosphonate derivatives

    Article • Mendeleev Communications, July 2017, Elsevier

    Dr. Pavel N. Solyev

  74. New tools in nucleoside toolbox of tick-borne encephalitis virus reproduction inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, March 2017, Elsevier

    Dr. Pavel N. Solyev

  75. Selective N1-Alkylation of 1,3-Dibenzoyluracils: One-Pot Way to N1-Monosubstituted Uracil Derivatives

    Article • Heterocycles, January 2017, Japan Institute of Heterocyclic Chemistry

    Dr. Pavel N. Solyev

  76. 5-(4-alkyl-1,2,3-triazol-1-yl)methyl derivatives of 2′-deoxyuridine as inhibitors of viral and bacterial growth

    Article • Russian Journal of Bioorganic Chemistry, November 2016, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  77. ONH2-functionalized Sepharose and Toyopearl resins

    Article • Russian Journal of Bioorganic Chemistry, September 2016, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev

  78. New acyclic nucleotide antiviral agents with oxime fragment in the chain

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Dr. Pavel N. Solyev

  79. Simple oximes of 3′-O-aminothymidine inhibit HIV replication

    Article • Heterocyclic Communications, January 2015, De Gruyter

    Dr. Pavel N. Solyev

  80. 1,3-Dipolar cycloaddition of alkenes to 3’-azido-3’-deoxythymidine as a route to 3’-deoxythymidin-3’-yl derivatives

    Article • Mendeleev Communications, July 2014, Elsevier

    Dr. Pavel N. Solyev

  81. New Dinucleoside Phosphonate Derivatives as Prodrugs of 3′-Azido-3′-Deoxythymidine andβ-L-2′,3′-Dideoxy-3′-Thiacytidine: Synthesis and Anti-HIV Properties

    Article • Nucleosides Nucleotides & Nucleic Acids, February 2014, Taylor & Francis

    Dr. Pavel N. Solyev

  82. Synthesis and Anti-HIV Properties of New Carbamate Prodrugs of AZT

    Article • Chemical Biology & Drug Design, October 2012, Wiley

    Dr. Pavel N. Solyev

  83. 5′-Phosphonate Derivatives of 2′,3′-Dideoxy-3′-Thiacytidine as New Anti-HIV Prodrugs

    Article • Chemical Biology & Drug Design, May 2011, Wiley

    Dr. Pavel N. Solyev

  84. Phosphomonomorpholidates of the acyclic nucleosides bearing a double bond conjugated with the purine base

    Article • January 2011, Institute of Organic Chemistry & Biochemistry

    Dr. Pavel N. Solyev

  85. New derivatives of alkyl-and aminocarbonylphosphonic acids containing 3′-azido-3′-deoxythymidine

    Article • Russian Journal of Bioorganic Chemistry, December 2006, Pleiades Publishing Ltd

    Dr. Pavel N. Solyev