All Stories

  1. Evolutionary plasticity of bacterial surface layer protein exoskeletons

    Article • April 2025, Cold Spring Harbor Laboratory Press

    Dr Paula Salgado

  2. Structure of the RNA-dependent RNA polymerase P2 from the cystovirus φ8

    Article • Scientific Reports, October 2024, Springer Science + Business Media

    Dr Paula Salgado

  3. Cleavage of an engulfment peptidoglycan hydrolase by a sporulation signature protease in Clostridioides difficile

    Article • Molecular Microbiology, June 2024, Wiley

    Dr Paula Salgado

  4. An intact S-layer is advantageous to Clostridioides difficile within the host

    Article • PLoS Pathogens, June 2023, PLOS

    Dr Paula Salgado

  5. An intact S-layer is advantageous toClostridioides difficilewithin the host

    Article • November 2022, Cold Spring Harbor Laboratory Press

    Dr Paula Salgado

  6. Structure and assembly of the S-layer in C. difficile

    Article • Nature Communications, February 2022, Springer Science + Business Media

    Dr Paula Salgado

  7. Metabolic cofactors NADH and FAD act as non-canonical initiating substrates for a primase and affect replication primer processing in vitro

    Article • Nucleic Acids Research, May 2020, Oxford University Press (OUP)

    Dr Paula Salgado

  8. A practical overview of molecular replacement: Clostridioides difficile PilA1, a difficult case study

    Article • Acta Crystallographica Section D Structural Biology, February 2020, International Union of Crystallography

    Dr Paula Salgado

  9. The engulfasome in C. difficile: Variations on protein machineries

    Article • Anaerobe, August 2019, Elsevier

    Dr Paula Salgado

  10. Peptidoglycan degradation machinery in Clostridium difficile forespore engulfment

    Article • Molecular Microbiology, July 2018, Wiley

    Dr Paula Salgado

  11. Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs

    Article • mBio, March 2018, ASM Journals

    Dr Paula Salgado

  12. Inducible Expression of spo0A as a Universal Tool for Studying Sporulation in Clostridium difficile

    Article • Frontiers in Microbiology, September 2017, Frontiers

    Dr Paula Salgado

  13. The SpoIIQ-SpoIIIAH complex ofClostridium difficilecontrols forespore engulfment and late stages of gene expression and spore morphogenesis

    Article • Molecular Microbiology, February 2016, Wiley

    Prof Adriano O. Henriques, Dr Paula Salgado

  14. In vacuo X-ray data collection from graphene-wrapped protein crystals

    Article • Acta Crystallographica Section D Biological Crystallography, September 2015, International Union of Crystallography

    Dr Gwyndaf Evans, Dr Anna J Warren, Dr Paula Salgado

  15. A mother cell-to-forespore channel: current understanding and future challenges

    Article • FEMS Microbiology Letters, August 2014, Oxford University Press (OUP)

    Prof Adriano O. Henriques, Dr Paula Salgado

  16. The Peptide-binding Cavity Is Essential for Als3-mediated Adhesion ofCandida albicansto Human Cells

    Article • Journal of Biological Chemistry, May 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Paula Salgado

  17. Regulation of thePlasmodiumMotor Complex

    Article • Journal of Biological Chemistry, August 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Paula Salgado

  18. Promoting crystallisation of the Salmonella enteritidis fimbriae 14 pilin SefD using deuterium oxide

    Article • May 2012, Elsevier

    Dr Paula Salgado

  19. Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus Candida albicans

    Article • Proceedings of the National Academy of Sciences, September 2011, Proceedings of the National Academy of Sciences

    Dr Paula Salgado

  20. Atomic Resolution Insights into Curli Fiber Biogenesis

    Article • September 2011, Elsevier

    Dr Paula Salgado

  21. Expression, crystallization and preliminary X-ray data analysis of NT-Als9-2, a fungal adhesin fromCandida albicans

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, March 2011, International Union of Crystallography

    Dr Paula Salgado

  22. Extending the usability of the phasing power of diselenide bonds: SeCys SAD phasing of CsgC using a non-auxotrophic strain

    Article • Acta Crystallographica Section D Biological Crystallography, December 2010, International Union of Crystallography

    Dr Paula Salgado

  23. Structural explanation for the role of Mn2+ in the activity of ϕ6 RNA-dependent RNA polymerase

    Article • Nucleic Acids Research, October 2008, Oxford University Press (OUP)

    Dr Paula Salgado

  24. The Structure of an RNAi Polymerase Links RNA Silencing and Transcription

    Article • PLoS Biology, December 2006, PLOS

    Dr Paula Salgado

  25. Back-priming mode of  6 RNA-dependent RNA polymerase

    Article • Journal of General Virology, February 2005, Society for General Microbiology

    Dr Paula Salgado

  26. Gene silencing pathway RNA-dependent RNA polymerase of Neurospora crassa: yeast expression and crystallization of selenomethionated QDE-1 protein

    Article • January 2005, Elsevier

    Dr Paula Salgado

  27. Going soft and SAD with manganese

    Article • Acta Crystallographica Section D Biological Crystallography, December 2004, International Union of Crystallography

    Dr Martin Austin Walsh, Dr Paula Salgado

  28. The Structural Basis for RNA Specificity and Ca2+ Inhibition of an RNA-Dependent RNA Polymerase

    Article • Structure, February 2004, Elsevier

    Dr Sarah Jane Butcher, Dr Paula Salgado

  29. The Structural Basis for RNA Specificity and Ca Inhibition of an RNA-Dependent RNA Polymerase

    Article • Structure, February 2004, Elsevier

    Dr Sarah Jane Butcher, Dr Paula Salgado