All Stories

  1. Syzygium aromaticum Attenuates Cerebellar Oxidative Stress: An Integrated in silico, in vitro, and in vivo Evaluation of Multi-Target Antioxidant Mechanisms
  2. Educational Leadership for Sustainable Capacity Building Towards Enhancing Interdisciplinary Collaboration in Computer‐Aided Drug Design and Network Pharmacology: A Systematic Review
  3. Influence of dietary patterns on cognitive decline and neurodegenerative processes among older adults
  4. Disparities in Low‐Birth‐Weight Prevalence Across Kenya: A Systematic Review and Meta‐Analysis of Maternal, Demographic, and Socioeconomic Risk Factors
  5. Gut Microbiota Resilience and Environmental Stressors: A Hidden Key to Lifespan Optimization?
  6. Unlocking the potential of endophytes in enhancing plant secondary metabolite biosynthesis
  7. Therapeutic and health-promoting perspectives of the functional pseudocereal buckwheat (Fagopyrum esculentum)
  8. Unlocking the Potential of Cucurbitaceae Seed Oils: A Narrative Review on Phytochemical, Pharmacological, and Biotechnological Applications
  9. Hesperidin Suppresses Complete Freund's Adjuvant (CFA)-Induced Rheumatoid Arthritis (RA) in Wistar Albino Rats by Targeting TNF-α/IL-6/IL-1β and NF-κB/COX-2 Pathways
  10. Innovative HIV care strategies and health system resilience in conflict-affected settings
  11. Nanoparticles in HIV treatment for improved drug delivery, clinical translation, and future direction
  12. Hesperidin as an Emerging Nutraceutical for Management of Diverse Metabolic Syndrome: A Narrative Review on in vivo and in silico Experiments
  13. Antidiabetic Efficacy and Mechanistic Insights of Azadirachta indica : A Systematic Review and Meta‐Analysis of Preclinical Evidence With Nutraceutical Applications
  14. Molecular, immunological and oncogenic mechanisms of cervical cancer mediated by HPV/HIV co-infection, clinical implication and management
  15. Gut microbiota at the crossroads of food additives, pollutants, and chronic disease risk
  16. Endocrine disruption rewards: bisphenol-A-induced reproductive toxicity and the precision ameliorative potential of flavonoids in preclinical studies. A systematic review and meta-analysis
  17. Preclinical outcomes of antioxidant therapy in traumatic brain injury-a systematic review
  18. Quantitative and health risks evaluations of trace metals in soils and cassava tubers cultivated in farms around abandoned Ishiagu mining sites, Ebonyi State, Nigeria
  19. The Role of AI-Powered Neuroimaging in Brain Tumor Diagnosis, Management, Challenges, and Future Directions
  20. The Impact of Antiretroviral Therapy (ART) on HPV Persistence and Cervical Cancer Progression Among Women with HPV/HIV Co-infection: A Systematic Review
  21. Public health burden of polycyclic aromatic hydrocarbons in the East African environment: a systematic review
  22. Gas Chromatography-Mass spectrometry (GC-MS) Revealed Bioactive Constituents of Brassica oleracea var. viridis (Collard Greens) Used to Treat Male Infertility in Uganda.
  23. Impact of antibiotics on the genomic expression of Pseudomonas aeruginosa in the East African community: a systematic review
  24. Plant-based management of Iron Deficiency Anemia (IDA) in East Africa community: a systematic review
  25. Integrated Assessment of Antioxidant Defense, Phytohormonal Responses, and Rhizomicrobial Dynamics in Maize Cultivated on Heavy Metal Impacted Mining Soils, Kilembe, Uganda.
  26. Mechanisms of cancer-induced neurophysiological dysfunction and therapeutic strategies
  27. Historical and ethnopharmacological perspectives on African medicinal plants: From traditional remedies to computational drug discovery
  28. Natural product-based inhibitors of quorum sensing: A novel approach to combat antibiotic resistance
  29. Ameliorative effects of Brassica oleracea var. viridis ethanol extract and fractions on cimetidine-induced reproductive toxicity in male Wistar rats
  30. Molecular Mechanisms of Antimicrobial Resistance in Infectious Diseases: Advances in Therapeutic Strategies and Public Health Interventions
  31. Mushroom marvels: understanding their role in human health
  32. Epitranscriptomic alterations induced by environmental toxins: implications for RNA modifications and disease
  33. Exploring the Neuroprotective Potentials of Flavonoid Metabolites in Syzygium aromaticum: A Review with in-silico Insight to Therapeutic Potential
  34. Exploring the phytochemical profile, antioxidant and anti-inflammatory potential of Bidens pilosa: A Systematic Review
  35. Unveiling the therapeutic potential of the gut microbiota–brain axis: Novel insights and clinical applications in neurological disorders
  36. THE PROTECTIVE ROLE OF FLAVONOIDS IN AMNESIA -SYSTEMATIC REVIEW
  37. PM2.5 Exposure and Depression in Pregnant Women: A Systematic Review and Meta-Analysis
  38. Phytochemical profiling and quantification of bioactive constituents in lyophilized khat (Catha edulis Forsk) leaf extract from central Uganda
  39. Unveiling the Fertility Potential of Brassica oleracea: In Silico and In vivo Insights into Protein Kinase B (PKB/AKT1) and Epidermal Growth Factor Receptor (EGFR) Inhibition
  40. Generational insights into testicular toxicity: unravelling typical causes, diagnostics, and nutraceutical strategies
  41. Preclinical evidence of the efficacy of cucurbita plants in diabetes management: a systematic review
  42. Lycopene Alleviates Lipid Dysregulation, Oxidative Stress, and Hypercholesterolemia in Obese Rats Subjected to a High‐Fat Diet
  43. Amino acid profiling and vitamin content of Spondias mombin , Canarium schweinfurthii, and Citrus sinensis
  44. Antioxidant activity and phytochemical analysis of different varieties of barley (Hordeum vulgare L.) available in Pakistan
  45. Phenolic-rich fraction of Solanum betaceum mitigates atorvastatin-induced myotoxicity through antioxidant mechanisms in female wistar rats
  46. The Role of Phytochemicals in Age-Related Cognitive Decline: A Natural Solution for Brain Health
  47. Gas Chromatography-Mass spectrometric (GC-MS) Revealed Bioactive Constituents of Brassica Oleracea var. Viridis (Collard Greens) Used as Ethnomedicine to Treat Male Infertility in Uganda
  48. Comparative effect of Chamomile flower ( Matricaria chamomilla L.) andPassion flower ( Passiflora incarnata L.) powder tea in patients suffering from primary insomnia
  49. Systematic identification of P48 as an advantageous diagnostic protein for Mycoplasma bovis infections: A literature survey and computational insight
  50. Role of protein intake in maintaining muscle mass composition among elderly females suffering from sarcopenia
  51. Health benefits of fish and fish by-products—a nutritional and functional perspective
  52. Lipid-based nano-carriers for the delivery of anti-obesity natural compounds: advances in targeted delivery and precision therapeutics
  53. RNA research for drug discovery: Recent advances and critical insight
  54. Exploring the male fertility potential of medicinal plants from central and West African countries: A systematic review
  55. Integrative Approaches to Prostate Disease Management: Nutrition, Exercise, and Lifestyle Modifications
  56. Exploring the use of phytotherapy in benign prostatic hyperplasia [BPH]: a systematic review
  57. Bisphenol-A (BPA) Exposure as a Risk Factor for Non-Communicable Diseases
  58. Recent focus in non-SELEX-computational approach for de novo aptamer design: A mini review
  59. Phytochemicals and pharmacology of pomegranate (Punica granatum L.): nutraceutical benefits and industrial applications: a review
  60. Ethanolic extract of Cnidoscolus aconitifolius leaves alleviates insulin resistance by modulating oxidative stress and inflammation in albino rats exposed to heavy metal mixture
  61. Prophylactic administration of naringin prevents anticancer drug 5-fluorouracil-induced hepatorenal toxicity via suppressing lipid peroxidation and oxidative stress in rats
  62. Systematic review of peptide nanoparticles for improved diabetes outcomes: insights and opportunities
  63. The role of pharmacological interventions in managing urological complications during pregnancy and childbirth: A review
  64. The impact of HPV/HIV co-infection on immunosuppression, HPV genotype, and cervical cancer biomarkers
  65. A systematic review of plant-based therapy for the management of diabetes mellitus in the East Africa community
  66. Medicinal plants with neuroprotective potential in East African countries: A systematic review
  67. Utilizing Indigenous Flora in East Africa for Breast Cancer Treatment: An Overview
  68. Artocarpus heterophyllus Seed Oil Mitigates Oxidative Stress and Lipid Profile in Alloxan-Induced Diabetic albino rats
  69. Advances and future directions of aptamer-functionalized nanoparticles for point-of-care diseases diagnosis
  70. Cucumeropsis mannii seed oil shields against cyclophosphamide-induced hepatorenal toxicity by modulating redox imbalance and iNOS/IL-β1 signalling in rats
  71. Impact of Antibiotics on the Genomic Expression ofPseudomonas aeruginosain the East African Community: A Systematic Review
  72. Exploring the versatility of Drosophila melanogaster as a model organism in biomedical research: a comprehensive review
  73. Innovative approaches to benign prostatic hyperplasia management: Options beyond conventional treatment strategies
  74. Curcuma longaEssential Oil Topically Mitigates Inflammatory Markers in Acetone-Induced Atopic Dermatitis in Wistar Albino Rats
  75. Chronic administration of Musa acuminata Colla (BANANA) to Wistar albino rats induces hyperkalemia
  76. The Therapeutic Role of Gastrodin in Combating Insulin Resistance, Inflammation, and Oxidative Stress Induced by Bisphenol-A
  77. Protective effect of Ficus capensis lyophilized extract against carboplatin-induced liver injury via inhibition of oxidative stress and inflammation in rats
  78. Azadirachta indica fruit juice clears malaria parasites and replenishes blood levels in Plasmodium berghei-infected mice
  79. Stem extract from Costus afer (Bush cane) prevents ethanol-induced neuronal degeneration in mice via an antioxidant-inflammatory pathway
  80. Cucurbita Pepo L. Seed Oil Modulates Dyslipidemia and Neuronal Dysfunction in Tramadol-Induced Toxicity in Wistar Albino Rats
  81. Cucumeropsis mannii seed oil (CMSO) restores testicular mitochondrial dysfunctions by modulating the activities of dysregulated testicular mitochondrial enzymes in male albino rats exposed to bisphenol A
  82. Quantitative and Health Risks Evaluations of Trace Metals in Soils and Cassava Tubers Cultivated in Farms Around Abandoned Ishiagu Mining Sites, Ebonyi State, Nigeria
  83. Cucumeropsis mannii seed oil mitigates bisphenol-A-induced sperm and hormonal damages in F1-generation of F0-exposed male rats: An in-vivo and in-silico analysis
  84. A critical review of the limitations of current diagnostic techniques for schistosomiasis
  85. Soluble platelet selectin and platelets in COVID-19: a multifaceted connection
  86. Ethnobotany, pharmacology and phytochemistry of medicinal plants used for management of Diabetes mellitus in Uganda, Kenya, Tanzania and the Democratic Republic of Congo
  87. A review of medicinal plants used for the restoration of reproductive functionality following cimetidine-induced reproductive toxicity
  88. Renoprotective effects of Cucumeropsis mannii seed oil on cisplatin-induced nephrotoxicity in Wistar rats
  89. WITHDRAWN: Effects of ethyl acetate fraction ofPsychotria vogelianaleaf on liver function, kidney function, and cytokines level of induced rheumatoid arthritis in albino rats
  90. Xylopia aethiopica Attenuates Oxidative Stress and Hepatorenal Damage in Testosterone Propionate-Induced Benign Prostatic Hyperplasia in Rats
  91. Ameliorative Potential of Pumpkin Seed Oil (Cucurbita pepo L.) Against Tramadol-Induced Oxidative Stress
  92. Methanol Crude Peel Extract of P. granatum Prevents Oxidative Damage in Kidneys of Rats Exposed to Highly Active Antiretroviral Therapy
  93. Cucumeropsis Mannii Seed Oil Reduces the Damage to the Kidneys in a Rat Model that Has Been Exposed to Cisplatin by Downregulating Cytokines and the Apoptotic Pathway
  94. Point-of-care potentials of lateral flow-based field screening for Mycoplasma bovis infections: a literature review
  95. Cucumeropsis mannii seed oil protects against bisphenol A-induced hepatotoxicity by mitigating inflammation and oxidative stress in rats
  96. Restorative effects of ethanolic leaf extract of Datura stramonium against methotrexate-induced hematological impairments
  97. Nutritional Intervention and Therapeutic Use of Azadirachta Indica (Neem) Fruit Juice as It Clears Malaria Parasites and Replenishes Depleted Blood Levels in Plasmodium Berghei Infected Swiss Albino Mice
  98. Buchholzia coriacea Leaves Attenuated Dyslipidemia and Oxidative Stress in Hyperlipidemic Rats and Its Potential Targets In Silico
  99. Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management
  100. Naringenin: its chemistry and roles in neuroprotection
  101. Advances in Alzheimer’s disease therapeutics: biochemistry, exploring bioactive compounds and novel approaches
  102. Hesperidin plays beneficial roles in disorders associated with the central nervous system: a review
  103. Safety profile of colocasia esculenta tuber extracts in benign prostate hyperplasia
  104. In Vivo and in Silico Assessment of Ameliorative Effects of Xylopia aethiopica on Testosterone Propionate-Induced Benign Prostatic Hyperplasia
  105. High‐pressure acidified steaming with varied citric acid dosing can successfully detoxify mycotoxins
  106. In-vivo and in-silico studies revealed the molecular mechanisms of Colocasia esculenta phenolics as novel chemotherapy against benign prostatic hyperplasia via inhibition of 5α-reductase and α1-adrenoceptor
  107. Cucumeropsis mannii seed oil ameliorates Bisphenol‐A‐induced adipokines dysfunctions and dyslipidemia
  108. Cucumeropsis mannii seed oil protects against Bisphenol A ‐induced testicular mitochondrial damages
  109. New Psychoactive Substances: Major Groups, Laboratory Testing Challenges, Public Health Concerns, and Community-Based Solutions
  110. In-Vivo and In-silico Studies Revealed the Molecular Mechanisms of Colocasia esculenta Phenolics as Novel Chemotherapy against Benign Prostatic Hyperplasia via inhibition of 5α‒Reductase and α1-Adrenoceptor.
  111. Combating Lassa Fever in West African Sub-Region: Progress, Challenges, and Future Perspectives
  112. Antioxidant, phytochemical, and therapeutic properties of medicinal plants: a review
  113. Ethanolic leaf extract ofDatura stramoniumattenuates methotrexate-induced biochemical alterations in Wistar Albino rats
  114. UCP-LF and other assay methods for schistosome circulating anodic antigen between 1978 and 2022
  115. An in silico study of bioactive compounds of Annona muricata in the design of ani-prostate cancer agent: MM/GBSA, pharmacophore modeling and ADMET parameters
  116. Elucidation of chemical profiles and molecular targets of Mondia whitei leave fractions bioactive as novel therapeutics: an in vitro and in silico assay
  117. A world free of malaria: It is time for Africa to actively champion and take leadership of elimination and eradication strategies
  118. Current Advances in the Management of Diabetes Mellitus
  119. Research Notes: Harnessing the nutritional benefits of pineapple pulp fiber to enhance antioxidant potential of wheat flour
  120. Safety profile of Colocasia esculenta tuber extracts in benign prostate hyperplasia
  121. Phytochemicals from medicinal plants from African forests with potentials in rheumatoid arthritis management
  122. Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Exhibits Antioxidant Mechanism for Abrogation of Cyclophosphamide-Induced Cardiac Damage and Oxidative Hepatorenal Toxicity in Rats
  123. Gas chromatographic-mass spectrometric (GC-MS) analysis and virtual screening of ripped fruit of Dialium guineense for potential inhibitors of integrase, cycloxygenase-1, and xanthine oxidase
  124. An Overview of COVID-19 in Sub-Saharan Africa: the Transmissibility,Pathogenicity, Morbidity and Mortality so far
  125. Hesperidin abrogates bisphenol A endocrine disruption through binding with fibroblast growth factor 21 (FGF-21), α-amylase and α-glucosidase: an in silico molecular study
  126. <i>Cleistopholis patens</i> Extracts Attenuate Inflammatory Cytokine and Oxidative Stress Status in Complete Freund’s Adjuvant-induced Rheumatoid Arthritis in Wistar Albino Rats
  127. ANTIOXIDANT EFFECT OF Buchholzia coriacea ETHANOL LEAF-EXTRACT AND FRACTIONS ON FREUND’S ADJUVANT-INDUCED ARTHRITIS IN ALBINO RATS: A COMPARATIVE STUDY
  128. Cucumeropsis mannii seed oil (CMSO) attenuates alterations in testicular biochemistry and histology against Bisphenol a-induced toxicity in male Wister albino rats
  129. Cucumeropsis mannii seed oil (CMSO) ameliorates adipokines dysfunction and dyslipidemia in male Wistar rats exposed to Bisphenol-A
  130. Amino acid profiles of Solanum aethiopicum, Amaranthus hybridus, and Telfairia occidentalis, common leafy vegetables in Nigeria
  131. Halotolerant and metalotolerant bacteria strains with heavy metals biorestoration possibilities isolated from Uburu Salt Lake, Southeastern, Nigeria
  132. Prospect into therapeutic potentials of Moringa oleifera phytocompounds against cancer upsurge: de novo synthesis of test compounds, molecular docking, and ADMET studies
  133. Cocoyam (Colocasia esculenta) modulates some parameters of testosterone propionate-induced rat model of benign prostatic hyperplasia
  134. Ethanol leaf extract of Ruspolia hypocrateriformis abrogated hepatic redox imbalance and oxidative damage induced by heavy metal toxicity in rats
  135. Hesperidin protects against cadmium-induced pancreatitis by modulating insulin secretion, redox imbalance and iNOS/NF-ĸB signaling in rats
  136. Antibacterial activities of Camellia sinensis plant extracts against uropathogenic E. coli in vitro and in vivo
  137. Vitamins, Amino Acids and Antinutrient Compositions of Whitfieldia Lateritia Leaves
  138. Hesperidin ameliorates hepatic dysfunction and dyslipidemia in male Wistar rats exposed to cadmium chloride
  139. Moringa oleifera seed oil modulates redox imbalance and iNOS/NF-κB/caspase-3 signaling pathway to exert antioxidant, anti-inflammatory and antiapoptotic mechanisms against anticancer drug 5-fluorouracil-induced nephrotoxicity in rats
  140. Anti-arthritic potentials of ethanol and aqueous extracts of stem bark of Cleistopholis patens on complete Freund's adjuvant-induced rheumatoid arthritis in rats
  141. Ethanol Root-extract of Sphenocentrum jollyanum Restored Altered Haematological Markers in Plasmodium berghei-infected Mice
  142. Comparative Amino Acid Compositions of Curculigo pilosa Root and Citrullus colocynthis Fruit Bark
  143. Comparative Amino Acid Compositions of Uvaria chamae Stem Bark and Poly Herbal Mixture
  144. Effect of ethanol and aqueous extracts of seed pod of Copaifera salikounda (Heckel) on complete Freund's adjuvant‐induced rheumatoid arthritis in rats
  145. Effects of Aqueous and Ethanol Root Extracts of Olax subscopioidea on Inflammatory Parameters in Complete Freund’s Adjuvant-Collagen Type II Induced Arthritic Albino Rats
  146. Moringa oleifera seed oil or virgin coconut oil supplementation abrogates cerebral neurotoxicity induced by antineoplastic agent methotrexate by suppression of oxidative stress and neuro‐inflammation in rats
  147. Effect of ethanol extract of boiled breadfruit (Treculia Africana ) seed on the oral glucose tolerance, lipid profile, and body weight of normoglycemic albino rats
  148. Antioxidant and anti-inflammatory effects of virgin coconut oil supplementation abrogate acute chemotherapy oxidative nephrotoxicity induced by anticancer drug methotrexate in rats
  149. Characterization of 2,5-dimethyl-2,4-dihydroxy-3(2H) furanone, A Flavourant Principle From Sysepalum dulcificum
  150. Effect of Baygon Insecticide on the Activities of Total, Alkaline and Acid Phosphatases of Selected Tissues of Albino Rats
  151. Potentials of Afzelia Africana Vegetable Oil in Biodiesel Production
  152. Chemical and Antimicrobial Properties of Leaf Extracts of Zapoteca portoricensis
  153. Phytochemical Composition of Talinum triangulare (Water Leaf) Leaves
  154. Proximate Analysis of Talinum triangulare (Water Leaf) Leaves and its Softening Principle
  155. Hepatoprotective Effect of Aqueous Extract of Water Leaf (Talinum Triangulare) on Carbon tetrachloride (CCL4) Induced Liver Damage in Wistar Rats