All Stories

  1. AI-enabled forecasting of prehospital transfusion needs in patients with trauma: a multinational, registry-based, retrospective, machine learning development and validation study

    Article • The Lancet Digital Health, January 2026, Elsevier

    Patricia Maguire

  2. Nanoparticle Tracking Analysis and Its Application to Study the Role of Small Extracellular Vesicles in Health and Disease

    Article • January 2026, Springer Science + Business Media

    Patricia Maguire

  3. An optimized protocol to isolate quiescent washed platelets from human whole blood and generate platelet releasate under clinical conditions

    Article • STAR Protocols, June 2025, Elsevier

    Patricia Maguire

  4. Toward standardization and a concerted vision for platelet proteomics research: communication from the SSC of the ISTH

    Article • Journal of Thrombosis and Haemostasis, May 2025, Elsevier

    Patricia Maguire

  5. Direct Oral Anticoagulants Are Comparable to Low Molecular Weight Heparin at Sustaining the Circulating Extracellular Vesicle and Inflammatory Profiles of Cancer Associated Thrombosis Patients: An Observational Pilot Study

    Article • Cancer Medicine, April 2025, Wiley

    Patricia Maguire

  6. Production of platelets <i>in vitro</i> in functionalised 3-dimensional scaffolds mimicking the bone marrow niche

    Article • Haematologica, April 2025, Ferrata Storti Foundation (Haematologica)

    Patricia Maguire

  7. Unique Patterns of Circulating Extracellular Vesicles in Preterm Infants During Adaptation to Extra‐Uterine Life

    Article • Journal of Extracellular Vesicles, April 2025, Wiley

    Patricia Maguire

  8. Rivaroxaban, in combination with low-dose aspirin, is associated with a reduction in proinflammatory and prothrombotic circulating vesicle signatures in patients with cardiovascular disease

    Article • Journal of Thrombosis and Haemostasis, February 2025, Elsevier

    Patricia Maguire

  9. Characterisation of Platelet Releasate Proteome in Relapsing‐Remitting Multiple Sclerosis Reveals Dysregulation of Inflammatory Signalling and Extracellular Vesicle Dynamics

    Article • PROTEOMICS - CLINICAL APPLICATIONS, January 2025, Wiley

    Patricia Maguire

  10. Increasing clinical recruitment rate to a single-site observational study: a quality improvement study

    Article • BMJ Open Quality, January 2025, BMJ

    Patricia Maguire

  11. Platelet-derived extracellular vesicles in cardiovascular disease and treatment – from maintaining homeostasis to targeted drug delivery

    Article • Current Opinion in Hematology, October 2024, Wolters Kluwer Health

    Patricia Maguire

  12. Platelet proteomic profiling reveals potential mediators of immunothrombosis and proteostasis in myeloproliferative neoplasms

    Article • Blood Advances, August 2024, American Society of Hematology

    Patricia Maguire

  13. Extracellular vesicles in disorders of hemostasis following traumatic brain injury

    Article • Frontiers in Neurology, May 2024, Frontiers

    Patricia Maguire

  14. The effect of UVA light/8-methoxypsoralen exposure used in Extracorporeal Photopheresis treatment on platelets and extracellular vesicles

    Article • PLOS One, February 2024, PLOS

    Patricia Maguire

  15. Proteomic Analysis of Extracellular Vesicle Cargoes Mirror the Cardioprotective Effects of Rivaroxaban in Patients with Venous Thromboembolism

    Article • January 2024, Wiley

    Patricia Maguire

  16. Proteomic analysis of extracellular vesicle cargoes mirror the cardioprotective effects of rivaroxaban in patients with venous thromboembolism

    Article • PROTEOMICS - CLINICAL APPLICATIONS, January 2024, Wiley

    Patricia Maguire

  17. Platelet proteo-transcriptomic profiling validates mediators of thrombosis and proteostasis in patients with myeloproliferative neoplasms

    Article • October 2023, openRxiv

    Patricia Maguire

  18. The effect of UVA light/8-methoxypsoralen exposure used in Extracorporeal Photopheresis treatment on platelets and extracellular vesicles

    Article • October 2023, openRxiv

    Patricia Maguire

  19. OC 16.5 Rivaroxaban in Combination with Low-Dose Aspirin is Associated with a Reduction in Pro-Inflammatory and Pro-thrombotic Circulating Vesicle Signatures in Patients with Cardiovascular Disease

    Article • Research and Practice in Thrombosis and Haemostasis, October 2023, Elsevier

    Patricia Maguire

  20. OC 56.1 Platelets as Versatile Effectors of Thromboinflammation: An MPN Multi-Omics Collaborative

    Article • Research and Practice in Thrombosis and Haemostasis, October 2023, Elsevier

    Patricia Maguire

  21. PB1520 Deep Learning Extracts Embedded Signatures Associated with Pregnancy and Preeclampsia from Circulating Vesicle Profiles

    Article • Research and Practice in Thrombosis and Haemostasis, October 2023, Elsevier

    Patricia Maguire

  22. Markers of platelet activation foR identification of late onset sEpsis in infaNTs: PARENT study protocol

    Article • Pediatric Research, September 2023, Springer Science + Business Media

    Patricia Maguire

  23. Translating genomic tools to Raman spectroscopy analysis enables high-dimensional tissue characterization on molecular resolution

    Article • Nature Communications, September 2023, Springer Science + Business Media

    Patricia Maguire

  24. Calibrated automated thrombography demonstrates a hypocoagulable profile in subjects with pulmonary arterial hypertension

    Article • September 2023, European Respiratory Society (ERS)

    Patricia Maguire

  25. An optimized protocol to isolate quiescent washed platelets from human whole blood and generate platelet releasate under clinical conditions

    Article • STAR Protocols, June 2023, Elsevier

    Patricia Maguire

  26. AI in Haematology

    Article • March 2023, Wiley

    Patricia Maguire

  27. Tumor-Educated Platelet Extracellular Vesicles: Proteomic Profiling and Crosstalk with Colorectal Cancer Cells

    Article • Cancers, January 2023, MDPI AG

    Patricia Maguire

  28. Analysis of the Platelet Proteome Reveals Insights into the Pro-Inflammatory and Pro-Thrombotic State Associated with the Philadelphia Chromosome-Negative Myeloproliferative Neoplasms

    Article • Blood, November 2022, American Society of Hematology

    Patricia Maguire

  29. PO-08: Characterisation of plasma extracellular vesicles in myeloproliferative neoplasms

    Article • Thrombosis Research, May 2022, Elsevier

    Patricia Maguire

  30. ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury

    Article • Nature Communications, April 2022, Springer Science + Business Media

    Patricia Maguire

  31. Non‐severe COVID‐19 is associated with endothelial damage and hypercoagulability despite pharmacological thromboprophylaxis

    Article • Journal of Thrombosis and Haemostasis, April 2022, Elsevier

    Patricia Maguire

  32. Case Report: Hypergranular Platelets in Vaccine-Induced Thrombotic Thrombocytopenia After ChAdOx1 nCov-19 Vaccination

    Article • Frontiers in Cardiovascular Medicine, February 2022, Frontiers

    Patricia Maguire

  33. A dry immersion model of microgravity modulates platelet phenotype, miRNA signature, and circulating plasma protein biomarker profile

    Article • Scientific Reports, November 2021, Springer Science + Business Media

    Patricia Maguire

  34. COVID-19 Is Associated with Endothelial Dysfunction and Enhanced Plasma Thrombin Generation Despite Pharmacological Thromboprophylaxis

    Article • Blood, November 2021, American Society of Hematology

    Patricia Maguire

  35. Comprehensive Multi-Parameter Characterisation of Circulating Extracellular Vesicles from Rivaroxaban-Treated VTE Patients Reveals Reduced Inflammation and Ameliorated Endothelial Dysfunction

    Article • Blood, November 2021, American Society of Hematology

    Patricia Maguire

  36. The Effect of Platelets on Thrombin Generation in Cord Blood and Peripheral Neonatal Blood in the Premature Infant; The Event Study

    Article • Blood, November 2021, American Society of Hematology

    Patricia Maguire

  37. Haematological parameters and coagulation in umbilical cord blood following COVID-19 infection in pregnancy

    Article • European Journal of Obstetrics & Gynecology and Reproductive Biology, November 2021, Elsevier

    Patricia Maguire

  38. Platelets in pediatric and neonatal sepsis: novel mediators of the inflammatory cascade

    Article • Pediatric Research, October 2021, Springer Science + Business Media

    Patricia Maguire

  39. Nonvalvular atrial fibrillation patients anticoagulated with rivaroxaban compared with warfarin exhibit reduced circulating extracellular vesicles with attenuated pro‐inflammatory protein signatures

    Article • Journal of Thrombosis and Haemostasis, October 2021, Elsevier

    Patricia Maguire

  40. P-001. AI_PREMie: A novel risk stratification tool for preeclamptic-toxaemia

    Article • Pregnancy Hypertension, September 2021, Elsevier

    Patricia Maguire

  41. The role of the calibrated automated thrombogram in neonates: describing mechanisms of neonatal haemostasis and evaluating haemostatic drugs

    Article • European Journal of Pediatrics, July 2021, Springer Science + Business Media

    Patricia Maguire

  42. Routine Hematological Parameters May Be Predictors of COVID-19 Severity

    Article • Frontiers in Medicine, July 2021, Frontiers

    Patricia Maguire

  43. Function, Proteomic and miRomic Study of a Dry Immersion Model of Microgravity implicates the Wnt/Dkk1/AXIN1 axis in Prothrombotic Platelet Phenotype

    Article • July 2021, Research Square

    Patricia Maguire

  44. Platelets, extracellular vesicles and coagulation in pulmonary arterial hypertension

    Article • Pulmonary Circulation, June 2021, Wiley

    Patricia Maguire

  45. COVID-19 induces a hyperactive phenotype in circulating platelets

    Article • PLoS Biology, February 2021, PLOS

    Patricia Maguire

  46. The canine activated platelet secretome (CAPS): A translational model of thrombin‐evoked platelet activation response

    Article • Research and Practice in Thrombosis and Haemostasis, January 2021, Elsevier

    Patricia Maguire

  47. A review of the role of extracellular vesicles in neonatal physiology and pathology

    Article • Pediatric Research, November 2020, Springer Science + Business Media

    Patricia Maguire

  48. COVID-19 induces a hyperactive phenotype in circulating platelets

    Article • July 2020, openRxiv

    Patricia Maguire

  49. Comparative Platelet Releasate Proteomic Profiling of Acute Coronary Syndrome versus Stable Coronary Artery Disease

    Article • Frontiers in Cardiovascular Medicine, June 2020, Frontiers

    Patricia Maguire

  50. Pathophysiology of the Venous Thromboembolism Risk in Preeclampsia

    Article • Hämostaseologie, May 2020, Thieme Publishing Group

    Patricia Maguire

  51. Rivaroxaban Reduces the Levels of Extracellular Vesicles in Patients with Venous Thromboembolism and Non-Valvular Atrial Fibrillation

    Article • Blood, November 2019, American Society of Hematology

    Patricia Maguire

  52. Alterations in fibrin formation and fibrinolysis in early onset-preeclampsia: Association with disease severity

    Article • European Journal of Obstetrics & Gynecology and Reproductive Biology, October 2019, Elsevier

    Patricia Maguire

  53. Examining gender effects in different types of undergraduate science assessment

    Article • Irish Educational Studies, July 2019, Taylor & Francis

    Patricia Maguire

  54. Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome

    Article • PLOS One, January 2019, PLOS

    Patricia Maguire

  55. Liver stiffness and thrombin generation in compensated cirrhosis

    Article • Research and Practice in Thrombosis and Haemostasis, January 2019, Wiley

    Patricia Maguire

  56. Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells

    Article • Frontiers in Pharmacology, January 2019, Frontiers

    Patricia Maguire

  57. Characterization of Platelet Activation in Patients with Eisenmenger Syndrome

    Article • Blood, November 2018, American Society of Hematology

    Patricia Maguire

  58. The Hundred-Person Platelet Releasate Project (100PREPs): A Barcode for Human Health and Disease

    Article • Blood, November 2018, American Society of Hematology

    Patricia Maguire

  59. The Population of Circulating Extracellular Vesicles Dramatically Alters after Very Premature Delivery- a Previously Unrecognised Postnatal Adaptation Process?

    Article • Blood, November 2018, American Society of Hematology

    Patricia Maguire

  60. The Platelet Releasate is Altered in Human Pregnancy

    Article • PROTEOMICS - CLINICAL APPLICATIONS, October 2018, Wiley

    Patricia Maguire

  61. Front Cover: Platelet Releasate Proteome Profiling Reveals a Core Set of Proteins with Low Variance between Healthy Adults

    Article • PROTEOMICS, August 2018, Wiley

    Patricia Maguire

  62. Platelet Releasate Proteome Profiling Reveals a Core Set of Proteins with Low Variance between Healthy Adults

    Article • PROTEOMICS, July 2018, Wiley

    Patricia Maguire

  63. Dual endothelin-1 receptor antagonism attenuates platelet-mediated derangements of blood coagulation in Eisenmenger syndrome

    Article • Journal of Thrombosis and Haemostasis, June 2018, Wiley

    Patricia Maguire, Dr Elaine Neary

  64. Proteomic Analysis Reveals a Strong Association of β-Catenin With Cadherin Adherens Junctions in Resting Human Platelets

    Article • PROTEOMICS, May 2018, Wiley

    Patricia Maguire

  65. Early onset preeclampsia is associated with an elevated mean platelet volume (MPV) and a greater rise in MPV from time of booking compared with pregnant controls: results of the CAPE study

    Article • Journal of Perinatal Medicine, December 2017, De Gruyter

    Patricia Maguire

  66. Thrombin generation correlates with disease duration in multiple sclerosis (MS): Novel insights into the MS-associated prothrombotic state

    Article • Multiple Sclerosis Journal - Experimental Translational and Clinical, December 2017, SAGE Publications

    Patricia Maguire

  67. A Protocol for Improved Precision and Increased Confidence in Nanoparticle Tracking Analysis Concentration Measurements between 50 and 120 nm in Biological Fluids

    Article • Frontiers in Cardiovascular Medicine, November 2017, Frontiers

    Patricia Maguire

  68. Endothelial barrier protective properties of low molecular weight heparin: A novel potential tool in the prevention of cancer metastasis?

    Article • Research and Practice in Thrombosis and Haemostasis, June 2017, Wiley

    Dr Elaine Neary, Patricia Maguire

  69. Effect of platelet-derived β-thromboglobulins on coagulation

    Article • Thrombosis Research, June 2017, Elsevier

    Patricia Maguire

  70. Comparative proteomic analysis of trophoblast cell models reveals their differential phenotypes, potential uses, and limitations

    Article • PROTEOMICS, May 2017, Wiley

    Patricia Maguire

  71. Platelet extracellular vesicles induce a pro-inflammatory smooth muscle cell phenotype

    Article • Journal of Extracellular Vesicles, January 2017, Taylor & Francis

    Patricia Maguire

  72. Elevated plasma TFPI activity causes attenuated TF-dependent thrombin generation in early onset preeclampsia

    Article • Thrombosis and Haemostasis, January 2017, Schattauer GmbH

    Patricia Maguire

  73. Analysis of the proteins associated with platelet detergent resistant membranes

    Article • PROTEOMICS, September 2016, Wiley

    Patricia Maguire

  74. Increased soluble GPVI levels in cirrhosis: evidence for early in vivo platelet activation

    Article • Journal of Thrombosis and Thrombolysis, July 2016, Springer Science + Business Media

    Patricia Maguire

  75. 780: Coagulation balance in early onset preeclampsia (EOP)

    Article • American Journal of Obstetrics and Gynecology, January 2016, Elsevier

    Patricia Maguire

  76. Human Platelet Exosome Proteomics Leads to the Identification of WNT Positive Exosomes Which Impact Canonical WNT Signalling in Target Cells

    Article • Blood, December 2014, American Society of Hematology

    Patricia Maguire

  77. Platelet Derived Exosomes Are Enriched for Specific microRNAs Which Regulate WNT Signalling in Endothelial Cells

    Article • Blood, December 2014, American Society of Hematology

    Patricia Maguire

  78. Canonical Wnt signaling in megakaryocytes regulates proplatelet formation

    Article • Blood, November 2012, American Society of Hematology

    Patricia Maguire

  79. WNT-3a modulates platelet function by regulating small GTPase activity

    Article • FEBS Letters, June 2012, Wiley

    Patricia Maguire

  80. The MEIS1 Interactome in Megakaryocytes Reveals a Role in Cell Cycle Regulation,

    Article • Blood, November 2011, American Society of Hematology

    Patricia Maguire

  81. Novel Platelet Signalling Pathways Identified via Proteomics

    Article • Current Proteomics, October 2011, Bentham Science Publishers

    Patricia Maguire

  82. Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods

    Article • PROTEOMICS - CLINICAL APPLICATIONS, July 2011, Wiley

    Patricia Maguire

  83. Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function

    Article • Blood, September 2010, American Society of Hematology

    Patricia Maguire

  84. Canonical Wnt signaling negatively regulates platelet function

    Article • Proceedings of the National Academy of Sciences, November 2009, Proceedings of the National Academy of Sciences

    Patricia Maguire

  85. Differential stimulation of monocytic cells results in distinct populations of microparticles

    Article • Journal of Thrombosis and Haemostasis, June 2009, Wiley

    Patricia Maguire

  86. Differential Stimulation of Monocytic Cells Results in Distinct Populations of Microparticles

    Article • Blood, November 2008, American Society of Hematology

    Patricia Maguire

  87. Identification of Apolipoprotein AI as a serum biomarker of chronic kidney disease in liver transplant recipients, using proteomic techniques

    Article • PROTEOMICS - CLINICAL APPLICATIONS, September 2008, Wiley

    Patricia Maguire

  88. A proteomic approach to immune-mediated epithelial-mesenchymal transition

    Article • PROTEOMICS - CLINICAL APPLICATIONS, July 2008, Wiley

    Patricia Maguire

  89. Analysis of membrane microdomain-associated proteins in the insular cortex of post-mortem human brain

    Article • PROTEOMICS - CLINICAL APPLICATIONS, October 2007, Wiley

    Patricia Maguire

  90. Role of Streptococcus gordonii Surface Proteins SspA/SspB and Hsa in Platelet Function

    Article • Infection and Immunity, September 2007, ASM Journals

    Dr Nicholas S Jakubovics, Patricia Maguire

  91. Insights into the Platelet Releasate

    Article • Current Pharmaceutical Design, September 2007, Bentham Science Publishers

    Patricia Maguire

  92. Recent Advances in the Characterisation of the Platelet Membrane System by Proteomics

    Article • Current Pharmaceutical Design, September 2007, Bentham Science Publishers

    Patricia Maguire

  93. Moderation of the platelet releasate response by aspirin

    Article • Blood, June 2007, American Society of Hematology

    Patricia Maguire

  94. Correlation of probioticLactobacillus salivariusgrowth phase with its cell wall-associated proteome

    Article • FEMS Microbiology Letters, November 2005, Oxford University Press (OUP)

    Patricia Maguire

  95. Using proteomics to identify potential therapeutic targets in platelets

    Article • Biochemical Society Transactions, April 2005, Portland Press Ltd.

    Patricia Maguire

  96. Characterization of Platelet Lipid Rafts Leads to the Identification of RGS-19, Which Forms a Phosphorylation-Dependent Complex with 14-3-3ζ.

    Article • Blood, November 2004, American Society of Hematology

    Patricia Maguire

  97. Differential Agonist Stimulated Cytokine Release from Platelets: A Proteomics Approach.

    Article • Blood, November 2004, American Society of Hematology

    Patricia Maguire

  98. Application of Proteomics to the Study of Platelet Regulatory Mechanisms

    Article • Trends in Cardiovascular Medicine, August 2004, Elsevier

    Patricia Maguire

  99. Utilising proteomics to elucidate signalling pathways in the formation of platelet thrombin

    Article • European Journal of Anaesthesiology, June 2004, Wolters Kluwer Health

    Patricia Maguire

  100. Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions

    Article • Blood, March 2004, American Society of Hematology

    Patricia Maguire

  101. Integration of Proteomics and Genomics in Platelets

    Article • Molecular & Cellular Proteomics, November 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Patricia Maguire

  102. Platelet proteomics

    Article • Journal of Thrombosis and Haemostasis, July 2003, Wiley

    Patricia Maguire

  103. Proteomic analysis of proteins secreted by platelets

    Article • Journal of Thrombosis and Haemostasis, July 2003, Elsevier

    Patricia Maguire

  104. Platelet Proteomics: Identification of Potential Therapeutic Targets

    Article • Pathophysiology of Haemostasis and Thrombosis, January 2003, Karger Publishers

    Patricia Maguire

  105. Identification of the phosphotyrosine proteome from thrombin activated platelets

    Article • PROTEOMICS, June 2002, Wiley

    Patricia Maguire

  106. Effects of chronic low-frequency stimulation on Ca 2+ -regulatory membrane proteins in rabbit fast muscle

    Article • Pflügers Archiv - European Journal of Physiology, September 1999, Springer Science + Business Media

    Patricia Maguire

  107. Role of dystrophin isoforms and associated proteins in muscular dystrophy (review).

    Article • International Journal of Molecular Medicine, December 1998, Spandidos Publications

    Patricia Maguire

  108. Oligomerisation of calsequestrin from rabbit skeletal muscle

    Article • Biochemical Society Transactions, August 1998, Portland Press Ltd.

    Patricia Maguire

  109. Excitation-contraction-relaxation cycle: role of Ca2+-regulatory membrane proteins in normal, stimulated and pathological skeletal muscle (review).

    Article • International Journal of Molecular Medicine, April 1998, Spandidos Publications

    Patricia Maguire

  110. Oligomerization Is an Intrinsic Property of Calsequestrin in Normal and Transformed Skeletal Muscle

    Article • Biochemical and Biophysical Research Communications, November 1997, Elsevier

    Patricia Maguire

  111. Oligomerization of sarcoplasmic reticulum Ca2+-ATPase from rabbit skeletal muscle

    Article • FEBS Letters, November 1996, Wiley

    Patricia Maguire

  112. Enrichment of Phosphotyrosine Proteome of Human Platelets by Immunoprecipitation

    Article • Springer Science + Business Media

    Patricia Maguire

  113. Isolation of the Platelet Releasate

    Article • Springer Science + Business Media

    Patricia Maguire

  114. Platelet–Endothelial Interactions

    Article • Cambridge University Press

    Patricia Maguire