All Stories

  1. The Escherichia coli Radical SAM Enzyme YhcC Substitutes for the FAD-Dependent Oxidase Activity of MnmC in 5-Methylaminomethyl-2-Thiouridine tRNA Modification Under Anaerobic Conditions

    Article • May 2026, openRxiv

    Dr Patricia C Dos Santos

  2. Intricacies in iron–sulfur cluster function and biogenesis: functional versatility, sulfur sources, and enzyme specificity

    Article • RSC Chemical Biology, January 2026, Royal Society of Chemistry

    Dr Patricia C Dos Santos

  3. Interactions with sulfur acceptors modulate the reactivity of cysteine desulfurases and define their physiological functions

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, October 2024, Elsevier

    Dr Patricia C Dos Santos

  4. Sulfinamide Formation from the Reaction of Bacillithiol and Nitroxyl

    Article • ACS Chemical Biology, November 2023, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  5. Overview of physiological, biochemical, and regulatory aspects of nitrogen fixation in Azotobacter vinelandii

    Article • Critical Reviews in Biochemistry and Molecular Biology, November 2022, Taylor & Francis

    Dr Patricia C Dos Santos

  6. Sulfur Availability Impacts Accumulation of the 2-Thiouridine tRNA Modification in Bacillus subtilis

    Article • Journal of Bacteriology, May 2022, ASM Journals

    Dr Patricia C Dos Santos

  7. Extracurricular Functions of tRNA Modifications in Microorganisms

    Article • Genes, August 2020, MDPI AG

    Dr Patricia C Dos Santos

  8. Distribution of Nitrogen‐Fixation Genes in Prokaryotes Containing Alternative Nitrogenases

    Article • ChemBioChem, April 2020, Wiley

    Dr Patricia C Dos Santos

  9. The Thioredoxin System Reduces Protein Persulfide Intermediates Formed during the Synthesis of Thio-Cofactors in Bacillus subtilis

    Article • Biochemistry, March 2019, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  10. Metallocluster transactions: dynamic protein interactions guide the biosynthesis of Fe–S clusters in bacteria

    Article • Biochemical Society Transactions, October 2018, Portland Press Ltd.

    Dr Patricia C Dos Santos

  11. Metabolically healthy obese women have longer telomere length than obese women with metabolic syndrome

    Article • PLOS One, April 2017, PLOS

    Dr Patricia C Dos Santos

  12. Diverse Mechanisms of Sulfur Decoration in Bacterial tRNA and Their Cellular Functions

    Article • Biomolecules, March 2017, MDPI AG

    Dr Patricia C Dos Santos

  13. Trading Places—Switching Frataxin Function by a Single Amino Acid Substitution within the [Fe-S] Cluster Assembly Scaffold

    Article • PLoS Genetics, May 2015, PLOS

    Dr Patricia C Dos Santos

  14. Protective role of bacillithiol in superoxide stress and Fe–S metabolism in Bacillus subtilis

    Article • MicrobiologyOpen, May 2015, Wiley

    Dr Patricia C Dos Santos

  15. The relationship between plasma and salivary NOx

    Article • Nitric Oxide, May 2015, Elsevier

    Dr Patricia C Dos Santos

  16. Abbreviated Pathway for Biosynthesis of 2-Thiouridine in Bacillus subtilis

    Article • Journal of Bacteriology, March 2015, ASM Journals

    Dr Patricia C Dos Santos

  17. Fe-S Cluster Biogenesis in Gram-Positive Bacteria: SufU Is a Zinc-Dependent Sulfur Transfer Protein

    Article • Biochemistry, January 2014, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  18. Cross-functionalities of Bacillus deacetylases involved in bacillithiol biosynthesis and bacillithiol-S-conjugate detoxification pathways

    Article • Biochemical Journal, September 2013, Portland Press Ltd.

    Dr Patricia C Dos Santos

  19. Protected Sulfur Transfer Reactions by the Escherichia coli Suf System

    Article • Biochemistry, June 2013, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  20. P12

    Article • Nitric Oxide, April 2013, Elsevier

    Dr Patricia C Dos Santos

  21. Functional Analysis of Bacillus subtilis Genes Involved in the Biosynthesis of 4-Thiouridine in tRNA

    Article • Journal of Bacteriology, July 2012, ASM Journals

    Dr Patricia C Dos Santos

  22. Distribution of nitrogen fixation and nitrogenase-like sequences amongst microbial genomes

    Article • BMC Genomics, January 2012, Springer Science + Business Media

    Dr Patricia C Dos Santos

  23. Catalytic Mechanism of Sep-tRNA:Cys-tRNA Synthase

    Article • Journal of Biological Chemistry, December 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Patricia C Dos Santos

  24. Transcriptional Profiling of Nitrogen Fixation in Azotobacter vinelandii

    Article • Journal of Bacteriology, July 2011, ASM Journals

    Dr Patricia C Dos Santos

  25. P71. Nitrite formation through reduction of nitro-containing antibiotics

    Article • Nitric Oxide, May 2011, Elsevier

    Dr Patricia C Dos Santos

  26. Co-ordination and fine-tuning of nitrogen fixation in Azotobacter vinelandii

    Article • Molecular Microbiology, January 2011, Wiley

    Dr Patricia C Dos Santos

  27. Genomic Analysis of Nitrogen Fixation

    Article • January 2011, Springer Science + Business Media

    Dr Patricia C Dos Santos

  28. Molecular Biology and Genetic Engineering in Nitrogen Fixation

    Article • January 2011, Springer Science + Business Media

    Dr Patricia C Dos Santos

  29. Kinetic Analysis of the Bisubstrate Cysteine Desulfurase SufS from Bacillus subtilis

    Article • Biochemistry, October 2010, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  30. Characterization of the N -Acetyl-α- d -glucosaminyl l -Malate Synthase and Deacetylase Functions for Bacillithiol Biosynthesis in Bacillus anthracis ,

    Article • Biochemistry, September 2010, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  31. Electrons in Fe-S protein assembly

    Article • Nature Chemical Biology, September 2010, Springer Science + Business Media

    Dr Patricia C Dos Santos

  32. A substrate channel in the nitrogenase MoFe protein

    Article • JBIC Journal of Biological Inorganic Chemistry, May 2009, Springer Science + Business Media

    Dr Patricia C Dos Santos

  33. Genome Sequence of Azotobacter vinelandii, an Obligate Aerobe Specialized To Support Diverse Anaerobic Metabolic Processes

    Article • Journal of Bacteriology, May 2009, ASM Journals

    Dr Patricia C Dos Santos, Dr David J Studholme

  34. A newly discovered role for iron-sulfur clusters

    Article • Proceedings of the National Academy of Sciences, August 2008, Proceedings of the National Academy of Sciences

    Dr Patricia C Dos Santos

  35. In vivo iron–sulfur cluster formation

    Article • Proceedings of the National Academy of Sciences, June 2008, Proceedings of the National Academy of Sciences

    Dr Patricia C Dos Santos

  36. A Proposed Role for the Azotobacter vinelandii NfuA Protein as an Intermediate Iron-Sulfur Cluster Carrier

    Article • Journal of Biological Chemistry, March 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Patricia C Dos Santos

  37. Alkyne substrate interaction within the nitrogenase MoFe protein

    Article • Journal of Inorganic Biochemistry, November 2007, Elsevier

    Dr Patricia C Dos Santos

  38. Controlled Expression of nif and isc Iron-Sulfur Protein Maturation Components Reveals Target Specificity and Limited Functional Replacement between the Two Systems

    Article • Journal of Bacteriology, January 2007, ASM Journals

    Dr Patricia C Dos Santos

  39. Breaking the N2 triple bond: insights into the nitrogenase mechanism

    Article • Dalton Transactions, January 2006, Royal Society of Chemistry

    Dr Patricia C Dos Santos

  40. Intermediates Trapped during Nitrogenase Reduction of N⋮N, CH 3 −NNH, and H 2 N−NH 2

    Article • Journal of the American Chemical Society, November 2005, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  41. NifS-Mediated Assembly of [4Fe−4S] Clusters in the N- and C-Terminal Domains of the NifU Scaffold Protein†

    Article • Biochemistry, October 2005, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  42. Trapping a Hydrazine Reduction Intermediate on the Nitrogenase Active Site †

    Article • Biochemistry, June 2005, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  43. Trapping H - Bound to the Nitrogenase FeMo-Cofactor Active Site during H 2 Evolution:  Characterization by ENDOR Spectroscopy

    Article • Journal of the American Chemical Society, May 2005, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  44. Substrate Interactions with the Nitrogenase Active Site

    Article • Accounts of Chemical Research, March 2005, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  45. NifU and NifS are required for the maturation of nitrogenase and cannot replace the function of isc -gene products in Azotobacter vinelandii

    Article • Biochemical Society Transactions, February 2005, Portland Press Ltd.

    Dr Patricia C Dos Santos

  46. Characterization of Azotobacter vinelandii nifZ Deletion Strains: INDICATION OF STEPWISE MoFe PROTEIN ASSEMBLY

    Article • Journal of Biological Chemistry, October 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Patricia C Dos Santos

  47. Substrate Interaction at an Iron-Sulfur Face of the FeMo-cofactor during Nitrogenase Catalysis

    Article • Journal of Biological Chemistry, October 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Patricia C Dos Santos

  48. An Organometallic Intermediate during Alkyne Reduction by Nitrogenase

    Article • Journal of the American Chemical Society, August 2004, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  49. Localization of a Catalytic Intermediate Bound to the FeMo-cofactor of Nitrogenase

    Article • Journal of Biological Chemistry, June 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Patricia C Dos Santos

  50. Formation and Insertion of the Nitrogenase Iron-Molybdenum Cofactor

    Article • ChemInform, May 2004, Wiley

    Dr Patricia C Dos Santos

  51. Iron-Sulfur Cluster Assembly

    Article • Journal of Biological Chemistry, March 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Patricia C Dos Santos

  52. Formation and Insertion of the Nitrogenase Iron−Molybdenum Cofactor

    Article • Chemical Reviews, February 2004, American Chemical Society (ACS)

    Dr Patricia C Dos Santos

  53. Mammalian Transforming Growth Factor β1 Activated after Ingestion by Anopheles stephensi Modulates Mosquito Immunity

    Article • Infection and Immunity, June 2003, ASM Journals

    Dr Patricia C Dos Santos

  54. A Boophilus microplus vitellin-degrading cysteine endopeptidase

    Article • Parasitology, February 2003, Cambridge University Press

    Dr Patricia C Dos Santos

  55. 14. Fe-S assembly in Gram-positive bacteria

    Article • De Gruyter

    Dr Patricia C Dos Santos