All Stories

  1. Lipophilic Chemical Accumulation, a Systems Level Driver of Chronic Disease. An Integrated Multi-Omics and Toxicokinetic Framework

    Article • February 2026, MDPI AG

    Dr Patrice X. PETIT

  2. Caspase-8 and BID Caught in the Act with Cardiolipin: A New Platform to Provide Mitochondria with Microdomains of Apoptotic Signals

    Article • Cells, October 2025, MDPI AG

    Dr Patrice X. PETIT

  3. Cellular ATP levels alone do not reliably reflect overall mitochondrial bioenergetics or mitochondrial dysfunction in Barth syndrome

    Article • Journal of Translational Genetics and Genomics, July 2025, OAE Publishing

    Dr Patrice X. PETIT

  4. Reappraisal of the fundamental mechanisms of the sHA14-1 molecule as a Bcl-2/Bcl-XL ligand in the context of anticancer therapy: A cell biological study

    Article • Journal of Biological Methods, December 2024, Journal of Biological Methods

    Dr Patrice X. PETIT

  5. Sodium arsenite and arsenic trioxide differently affect the oxidative stress of lymphoblastoid cells: An intricate crosstalk between mitochondria, autophagy and cell death

    Article • PLOS One, May 2024, PLOS

    Dr Patrice X. PETIT

  6. Tafazzin Mutation Affecting Cardiolipin Leads to Increased Mitochondrial Superoxide Anions and Mitophagy Inhibition in Barth Syndrome

    Article • Cells, October 2020, MDPI AG

    Dr Patrice X. PETIT

  7. Curcumin, a Multifaceted Hormetic Agent, Mediates an Intricate Crosstalk between Mitochondrial Turnover, Autophagy, and Apoptosis

    Article • Oxidative Medicine and Cellular Longevity, July 2020, Hindawi Publishing Corporation

    Dr Patrice X. PETIT

  8. Highlighting Curcumin-Induced Crosstalk between Autophagy and Apoptosis as Supported by Its Specific Subcellular Localization

    Article • Cells, February 2020, MDPI AG

    Dr Patrice X. PETIT

  9. Iron chelation by curcumin suppresses both curcumin-induced autophagy and cell death together with iron overload neoplastic transformation

    Article • Cell Death Discovery, December 2019, Springer Science + Business Media

    Dr Patrice X. PETIT

  10. Synergistic cellular effects including mitochondrial destabilization, autophagy and apoptosis following low-level exposure to a mixture of lipophilic persistent organic pollutants

    Article • Scientific Reports, July 2017, Springer Science + Business Media

    Dr Patrice X. PETIT

  11. Curcumin hormesis mediates a cross-talk between autophagy and cell death

    Article • Cell Death and Disease, December 2015, Springer Science + Business Media

    Dr Patrice X. PETIT

  12. The iron component of particulate matter is antiapoptotic: A clue to the development of lung cancer after exposure to atmospheric pollutants?

    Article • Biochimie, November 2015, Elsevier

    Dr Patrice X. PETIT

  13. Curcumin induces crosstalk between autophagy and apoptosis mediated by calcium release from the endoplasmic reticulum, lysosomal destabilization and mitochondrial events

    Article • Cell Death Discovery, October 2015, Springer Science + Business Media

    Dr Patrice X. PETIT

  14. Barth syndrome: Cellular compensation of mitochondrial dysfunction and apoptosis inhibition due to changes in cardiolipin remodeling linked to tafazzin (TAZ) gene mutation

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, August 2013, Elsevier

    Dr Patrice X. PETIT

  15. Caspase-8 Binding to Cardiolipin in Giant Unilamellar Vesicles Provides a Functional Docking Platform for Bid

    Article • PLOS One, February 2013, PLOS

    Dr Patrice X. PETIT

  16. COUP-TFII Controls Mouse Pancreatic β-Cell Mass through GLP-1-β-Catenin Signaling Pathways

    Article • PLOS One, January 2012, PLOS

    Dr Patrice X. PETIT

  17. Mechanistic Issues of the Interaction of the Hairpin-Forming Domain of tBid with Mitochondrial Cardiolipin

    Article • PLOS One, February 2010, PLOS

    Dr Patrice X. PETIT

  18. Cross-Talk between Oxysterols and Glucocorticoids: Differential Regulation of Secreted Phopholipase A2 and Impact on Oligodendrocyte Death

    Article • PLOS One, November 2009, PLOS

    Dr Patrice X. PETIT

  19. Interaction of the alpha-helical H6 peptide from the pro-apoptotic protein tBid with cardiolipin

    Article • European Journal of Biochemistry, October 2009, Wiley

    Dr Patrice X. PETIT

  20. 25-hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR

    Article • Journal of Neurochemistry, May 2009, Wiley

    Dr Patrice X. PETIT

  21. The mitochondrial outer membrane protein import machinery: a new player in apoptosis?

    Article • Frontiers in Bioscience, January 2009, Frontiers in Bioscience

    Dr Patrice X. PETIT

  22. Lethal toxin fromClostridium sordelliiinduces apoptotic cell death by disruption of mitochondrial homeostasis in HL-60 cells

    Article • Cellular Microbiology, November 2003, Wiley

    Dr Patrice X. PETIT

  23. Retroactive pathway involving mitochondria in electroloaded cytochrome c-induced apoptosis

    Article • Experimental Cell Research, October 2003, Elsevier

    Dr Patrice X. PETIT

  24. Oxidation of pyridine nucleotides during Fas- and ceramide-induced apoptosis in Jurkat cells: correlation with changes in mitochondria, glutathione depletion, intracellular acidification and caspase 3 activation

    Article • Biochemical Journal, March 2001, Portland Press Ltd.

    Dr Patrice X. PETIT

  25. Oxidation of pyridine nucleotides during Fas- and ceramide-induced apoptosis in Jurkat cells: correlation with changes in mitochondria, glutathione depletion, intracellular acidification and caspase 3 activation

    Article • Biochemical Journal, January 2001, Portland Press Ltd.

    Dr Patrice X. PETIT

  26. Oxidation of pyridine nucleotides during Fas- and ceramide-induced apoptosis in Jurkat cells: correlation with changes in mitochondria, glutathione depletion, intracellular acidification and caspase 3 activation

    Article • Biochemical Journal, January 2001, Portland Press Ltd.

    Dr Patrice X. PETIT

  27. Over-expression of Bcl-2 does not protect cells from hypericin photo-induced mitochondrial membrane depolarization, but delays subsequent events in the apoptotic pathway

    Article • FEBS Letters, November 1999, Wiley

    Dr Patrice X. PETIT

  28. Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore

    Article • Oncogene, April 1999, Nature

    Dr Patrice X. PETIT

  29. Caspases disrupt mitochondrial membrane barrier function

    Article • FEBS Letters, May 1998, Wiley

    Dr Patrice X. PETIT

  30. Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition

    Article • FEBS Letters, April 1998, Wiley

    Dr Patrice X. PETIT

  31. Low Catalase Activity in Xeroderma Pigmentosum Fibroblasts and SV40-Transformed Human Cell Lines is Directly Related to Decreased Intracellular Levels of the Cofactor, NADPH

    Article • Free Radical Biology and Medicine, March 1998, Elsevier

    Dr Patrice X. PETIT

  32. Mitochondrial Regulation of Apoptosis

    Article • January 1998, Springer Science + Business Media

    Dr Patrice X. PETIT

  33. Contrôle mitochondrial de l'apoptose : la mort cellulaire programmée est-elle apparue à la suite de l'événement endosymbiotique à l'origine des mitochondries ?

    Article • médecine/sciences, January 1998, INIST-CNRS

    Dr Patrice X. PETIT

  34. A Cytofluorometric Assay of Nuclear Apoptosis Induced in a Cell-Free System: Application to Ceramide-Induced Apoptosis

    Article • Experimental Cell Research, November 1997, Elsevier

    Dr Patrice X. PETIT

  35. Induction of mitochondrial dysfunction and apoptosis in HeLa cells by bis-pyridinium oximes, a newly synthesized family of lipophilic biscations

    Article • Biochemical Pharmacology, May 1997, Elsevier

    Dr Patrice X. PETIT

  36. Implication of mitochondria in apoptosis

    Article • January 1997, Springer Science + Business Media

    Dr Patrice X. PETIT

  37. Mitochondria and programmed cell death: back to the future

    Article • FEBS Letters, October 1996, Wiley

    Dr Patrice X. PETIT

  38. Apoptosis of cells lacking mitochondrial DNA

    Article • APOPTOSIS, October 1996, Springer Science + Business Media

    Dr Patrice X. PETIT

  39. Discrimination of respiratory dysfunction in yeast mutants by confocal microscopy, image, and flow cytometry

    Article • Cytometry Part A, January 1996, Wiley

    Dr Patrice X. PETIT

  40. The biochemistry of programmed cell death

    Article • The FASEB Journal, October 1995, Wiley

    Dr Patrice X. PETIT

  41. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.

    Article • Journal of Experimental Medicine, August 1995, Rockefeller University Press

    Dr Patrice X. PETIT

  42. Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis

    Article • Journal of Cell Biology, July 1995, Rockefeller University Press

    Dr Patrice X. PETIT

  43. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

    Article • Journal of Experimental Medicine, May 1995, Rockefeller University Press

    Dr Patrice X. PETIT

  44. [41] Purification and characterization of plant mitochondria and submitochondrial particles

    Article • January 1994, Elsevier

    Dr Patrice X. PETIT

  45. Power and limits of laser scanning confocal microscopy

    Article • Biology of the Cell, January 1994, Wiley

    Dr Patrice X. PETIT

  46. Plant mitochondria contains a calcium-dependent protein kinase

    Article • FEBS Letters, December 1993, Wiley

    Dr Patrice X. PETIT

  47. FLOW AND IMAGE CYTOMETRY OF THE UNCOUPLING ACTIVITY OF HETEROLOGOUS PROTEINS EXPRESSED IN YEAST

    Article • Biology of the Cell, January 1993, Wiley

    Dr Patrice X. PETIT

  48. Mitochondrial dysfunction in yeast expressing the cytoplasmic male sterility T-urf13 gene from maize: analysis at the population and individual cell level

    Article • January 1993, Springer Science + Business Media

    Dr Patrice X. PETIT

  49. FAILURE OF THE MITOCHONDRIAL METABOLISM AND APOPTOSIS OF SV40 CONDITIONALLY IMMORTALIZED CELL LINES

    Article • Biology of the Cell, January 1993, Wiley

    Dr Patrice X. PETIT

  50. FLOW AND IMAGE CYTOMETRY OF THE UNCOUPLING ACTIVITY OF HETEROLOGOUS PROTEINS EXPRESSED IN YEAST

    Article • Biology of the Cell, January 1993, Wiley

    Dr Patrice X. PETIT

  51. Flow cytometry and plant protoplast cell biology

    Article • Physiologia Plantarum, June 1992, Wiley

    Dr Patrice X. PETIT

  52. Flow Cytometric Analysis of Rhodamine 123 Fluorescence during Modulation of the Membrane Potential in Plant Mitochondria

    Article • PLANT PHYSIOLOGY, January 1992, Oxford University Press (OUP)

    Dr Patrice X. PETIT

  53. Mitochondrial dysfunction in yeast expressing the cytoplasmic male sterility T-urf13 gene from maize: An image and flow cytometric analysis

    Article • Biology of the Cell, January 1992, Wiley

    Dr Patrice X. PETIT

  54. Properties of submitochondrial particles from plant mitochondria: generation, surface characteristics and NAD(P)H oxidation

    Article • Plant Science, January 1991, Elsevier

    Dr Patrice X. PETIT

  55. Modulation of endogenous protein phosphorylation in plant mitochondria by respiratory substrates

    Article • Physiologia Plantarum, December 1990, Wiley

    Dr Patrice X. PETIT

  56. Modulation of endogenous protein phosphorylation in plant mitochondria by respiratory substrates

    Article • Physiologia Plantarum, December 1990, Wiley

    Dr Patrice X. PETIT

  57. Analysis of the membrane potential of rat- and mouse-liver mitochondria by flow cytometry and possible applications

    Article • European Journal of Biochemistry, December 1990, Wiley

    Dr Patrice X. PETIT

  58. Endogenous protein phosphorylation in purified plant mitochondria

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, April 1990, Elsevier

    Dr Patrice X. PETIT

  59. Some properties of mitochondria, mitoplasts and submitochondrial particles of different polarities from plant tissues

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, March 1987, Elsevier

    Dr Patrice X. PETIT

  60. Generation and Characterization of Sub-Mitochondrial Particles: Isoelectric Points and Charge Surface Density of Plant Mitochondrial Membranes

    Article • January 1987, Springer Science + Business Media

    Dr Patrice X. PETIT

  61. Mitochondria from Zea mays leaf tissues: Differentiation of carbon assimilation and photorespiratory activity between mesophyll and bundle sheath cells

    Article • Physiologia Plantarum, July 1986, Wiley

    Dr Patrice X. PETIT

  62. Binding of concanavalin A to the outer membrane of potato tuber mitochondria detected by flow cytometry

    Article • FEBS Letters, February 1986, Wiley

    Dr Patrice X. PETIT

  63. Mitochondria from the Mesophyll Cells of Zea mays Leaves

    Article • Journal of Plant Physiology, January 1984, Elsevier

    Dr Patrice X. PETIT

  64. PURIFIED PHYTOLECTIN FROM THE LICHEN PELTIGERACANINA VAR CANINA WHICH BINDS TO THE PHYCOBIONT CELL WALLS AND ITS USE AS CYTOCHEMICAL MARKER IN SITU

    Article • New Phytologist, May 1983, Wiley

    Dr Patrice X. PETIT

  65. PHYTOLECTINS FROM THE NITROGEN-FIXING LICHEN PELTIGERA HORIZONTALIS: THE BINDING PATTERN OF PRIMARY PROTEIN EXTRACT

    Article • New Phytologist, August 1982, Wiley

    Dr Patrice X. PETIT

  66. Mitochondrial Implication in Cell Death

    Article • Springer Science + Business Media

    Dr Patrice X. PETIT

  67. Apoptosis

    Article • APOPTOSIS, Springer Science + Business Media

    Dr Patrice X. PETIT