All Stories

  1. Substrate Peptidomimetic Inhibitors of P. falciparum Plasmepsin X with Potent Antimalarial Activity

    Article • ChemMedChem, August 2022, Wiley

    Dr Brad E Sleebs, Dr. Paola Favuzza

  2. Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax

    Article • Structure, July 2022, Elsevier

    Dr Brad E Sleebs, Dr. Paola Favuzza

  3. Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity

    Article • Bioorganic Chemistry, December 2021, Elsevier

    Dr Brad E Sleebs, Dr. Paola Favuzza

  4. Optimisation of 2-(N-phenyl carboxamide) triazolopyrimidine antimalarials with moderate to slow acting erythrocytic stage activity

    Article • Bioorganic Chemistry, October 2021, Elsevier

    Dr Brad E Sleebs, Dr. Paola Favuzza

  5. Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle

    Article • Cell Host & Microbe, April 2020, Elsevier

    Dr Brad E Sleebs, Dr. Paola Favuzza

  6. Vaccination with virosomally formulated recombinant CyRPA elicits protective antibodies against Plasmodium falciparum parasites in preclinical in vitro and in vivo models

    Article • npj Vaccines, January 2020, Springer Science + Business Media

    Dr. Paola Favuzza

  7. Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody

    Article • eLife, February 2017, eLife

    Dr. Paola Favuzza

  8. Generation of monoclonal antibodies against native viral proteins using antigen-expressing mammalian cells for mouse immunization

    Article • BMC Biotechnology, November 2016, Springer Science + Business Media

    Dr. Paola Favuzza

  9. Generation of Plasmodium falciparum parasite-inhibitory antibodies by immunization with recombinantly-expressed CyRPA

    Article • Malaria Journal, March 2016, Springer Science + Business Media

    Dr. Paola Favuzza

  10. Passive Immunoprotection of Plasmodium falciparum-Infected Mice Designates the CyRPA as Candidate Malaria Vaccine Antigen

    Article • The Journal of Immunology, May 2012, The American Association of Immunologists

    Dr. Paola Favuzza