All Stories

  1. (E)-2-Benzylidenecyclanones: Part XXI—Reaction of Cyclic Chalcone Analogs with Cellular Thiols: Comparison of Reactivity of (E)-2-Arylidene-1-Indanone with -1-Tetralone and -1-Benzosuberone Analogs in Thia-Michael Reactions
  2. A comprehensive molecular description of sertraline hydrochloride: From solid state to electronic structure
  3. Centrally Acting Chalcones: From Anticancer and Antinociceptive Properties to Molecular Considerations
  4. (E)-2-Benzylidenecyclanones: Part XX—Reaction of Cyclic Chalcone Analogs with Cellular Thiols: Unexpected Increased Reactivity of 4-Chromanone- Compared to 1-Tetralone Analogs in Thia-Michael Reactions
  5. (E)-2-Benzylidenecyclanones: Part XX. Reaction of Cyclic Chalcone Analogs with Cellular Thiols. Unexpected Increased Reactivity of 4-Chromanone- Compared to 1-Tetralone-Analogs in Thia-Michael Reactions [1]
  6. (E)-2-Benzylidenecyclanones: Part XIX. Reaction of (E)-2-(4′-X-Benzylidene)-1-tetralones with Cellular Thiols: Comparison of Thiol Reactivities of Open-Chain Chalcones and Their Six- and Seven-Membered Cyclic Analogs
  7. (E)-2-Benzylidenecyclohexanones: Part XIX. Reaction Of (E)-2-(4′-X-benzylidene)-1-Tetralones with Cellular Thiols. Comparison of Thiol Reactivities of Open-Chain Chalcones and Their Six- and Seven-Membered Cyclic Analogs [1]
  8. Preface to the Special Issue “Glutathione: Chemistry and Biochemistry”
  9. Molecular modeling and solubility of olopatadine hydrochloride polymorphs
  10. (E)-2-Benzylidenecyclanones: Part XVIII Study the Possible Link between Glutathione Reactivity and Cancer Cell Cytotoxic Effects of Some Cyclic Chalcone Analogs A Comparison of the Reactivity of the Open-Chain and the Seven-Membered Homologs
  11. (E)-2-Benzylidenecyclanones: Part XVIII.[1] Study the Possible Link Between Glutathione Reactivity and Cancer Cell Cytotoxic Effects of Some Cyclic Chalcone Analogs. A Comparison of the Reactivity of the Open-Chain and the Seven-Membered Homologs
  12. (E)-2-Benzylidenecyclanones: Part XVII. An LC-MS study of microsomal transformation reactions of (E)-2-[(4'-methoxyphenyl)methylene]-benzosuberon-1-one: A cyclic chalcone analog
  13. Glutathione-Related Enzymes and Proteins: A Review
  14. Chlorine counterion effect into the supramolecular arrangement of phenylephrine solid state
  15. New Insights on Glutathione’s Supramolecular Arrangement and Its In Silico Analysis as an Angiotensin-Converting Enzyme Inhibitor
  16. HPLC and HPLC-MS Analysis of Intestinal Elimination and Phase 2 Metabolism of 4'-hydroxy-4-Methoxychalcone and its Bis-Mannich Analog In The Rat
  17. The Intestinal and Biliary Metabolites of Ibuprofen in the Rat with Experimental Hyperglycemia
  18. A new quinolinone-chalcone hybrid with potential antibacterial and herbicidal properties using in silico approaches
  19. Structural insights and supramolecular description of Gliclazide and its Impurity F
  20. Determination of steroid hormones in water samples by liquid chromatography electrospray ionization mass spectrometry using parallel reaction monitoring
  21. Michael addition reaction of symmetrically halogenated bischalcones with reduced glutathione assessed by RP-HPLC and RP-HPLC-ESI-MS
  22. Reaction of Chalcones with Cellular Thiols. The Effect of the 4-Substitution of Chalcones and Protonation State of the Thiols on the Addition Process. Diastereoselective Thiol Addition
  23. Insights on a new sulfonamide chalcone with potential antineoplastic application
  24. Starting Anti-COVID-19 Drug Discovery with Natural Products
  25. Alternative mechanisms of action for the apoptotic activity of terpenoid-like chalcone derivatives
  26. Study on the Interaction of 4'-Hydroxychalcones and their Mannich Derivatives with Calf Thymus DNA by TLC and Spectroscopic Methods, a DNA Cleavage Study
  27. The Relative Importance of the Small Intestine and the Liver in Phase II Metabolic Transformations and Elimination of p-Nitrophenol Administered in Different Doses in the Rat
  28. Pro-oxidative and antioxidant effects of salicylates
  29. Structure activity relationship analysis of antiproliferative cyclic C5-curcuminoids without DNA binding: Design, synthesis, lipophilicity and biological activity
  30. Investigation of intestinal elimination and biliary excretion of ibuprofen in hyperglycemic rats
  31. Toxicokinetic Study of a Gastroprotective Dose of Capsaicin by HPLC-FLD Method
  32. Different reactivity to glutathione but similar tumor cell toxicity of chalcones and their quinolinone analogues
  33. A novel cluster of C5-curcuminoids: design, synthesis, in vitro antiproliferative activity and DNA binding of bis(arylidene)-4-cyclanone derivatives based on 4-hydroxycyclohexanone scaffold
  34. HPLC study on Fenton-reaction initiated oxidation of salicylic acid. Biological relevance of the reaction in intestinal biotransformation of salicylic acid
  35. Changes in hepatic metabolic enzyme activities and biliary excretion of 4-nitrophenol in streptozotocin induced diabetic rats
  36. Reagent-induced asymmetric induction in addition reaction of reduced glutathione onto bis -Mannich chalcones
  37. Selected ferrocenyl chalcones as DNA/BSA-interacting agents and inhibitors of DNA topoisomerase I and II activity
  38. Oxidation of Hydroxy- and Dihydroxybenzoic Acids Under the Udenfriend's Conditions. An HPLC Study
  39. (E)-2-Benzylidenecyclanones: Part XV. Stereochemistry of Reaction of 2-Arylidenecyclopentanones with Dithiocarbamic Acid
  40. (E)-2-Benzylidenecyclanones: part XIV. Study on interaction of some (E)-2-benzylidenebenzosuberone derivatives with calf thymus DNA by TLC and UV–Vis methods, a DNA cleavage study
  41. HPLC analysis ofin vivointestinal absorption and oxidative metabolism of salicylic acid in the rat
  42. Chalcone derivatives cause accumulation of colon cancer cells in the G2/M phase and induce apoptosis
  43. Can the EGFR inhibitors increase the immunomodulatory effects of standardized plant extracts (mistletoe lectin and arabonoxylan) with clinical benefit? Case report of a patient with lung adenocarcinoma
  44. Study of Reactions of Two Mannich Bases Derived of 4’-Hydroxychalcones with Glutathione by RP‑TLC, RP‑HPLC and RP‑HPLC‑ESI‑MS Analysis
  45. Effect of experimental diabetes and insulin replacement on intestinal metabolism and excretion of 4-nitrophenol in rats
  46. Some ferrocenyl chalcones as useful candidates for cancer treatment
  47. (E)-2-Benzylidenebenzocyclanones: part XIII—(E)/(Z)-Isomerization of some cyclic chalcone analogues. Effect of ring size on lipophilicity of geometric isomers
  48. Synthesis and antiproliferative activity of cyclic arylidene ketones: a direct comparison of monobenzylidene and dibenzylidene derivatives
  49. (E)-2-Benzylidenecycloalkanones XII.* Kinetic Measurement of Bovine and Human Serum Albumine Interaction with Selected Chalcones and Their Cyclic Chalcone Analogues by UV Spectrophotometry
  50. A validated HPLC-FLD method for analysis of intestinal absorption and metabolism of capsaicin and dihydrocapsaicin in the rat
  51. Can a synergistic activation of pattern recognition receptors by plant immunomodulators enhance the effect of oncologic therapy? Case Report of a patient with uterus and ovary sarcoma
  52. Determination of Excited Singlet-State Dipole Moments of Methoxy and Dimethylamino Substituted Benzylidenebenzosuberones Using Solvatochromic Method
  53. Different effects of two cyclic chalcone analogues on redox status of Jurkat T cells
  54. Naturally occurring chalcones and their biological activities
  55. Spectroscopic Study on the Interaction of 4-dimethylaminochalcones with Phospholipids
  56. Capsaicin is a New Gastrointestinal Mucosal Protecting Drug Candidate in Humans — Pharmaceutical Development and Production Based on Clinical Pharmacology
  57. Pharmacobotanical analysis and regulatory qualification of Capsicum fruits and Capsicum extracts. A survey.
  58. Benzylidenetetralones, cyclic chalcone analogues, induce cell cycle arrest and apoptosis in HCT116 colorectal cancer cells
  59. 3-Benzylidene-4-chromanones: a novel cluster of anti-tubercular agents
  60. Further Aspects of Ochratoxin A-Cation Interactions: Complex Formation with Zinc Ions and a Novel Analytical Application of Ochratoxin A-Magnesium Interaction in the HPLC-FLD System
  61. Development and Validation of an HPLC-DAD Analysis for Pharmacopoeial Qualification of Industrial Capsicum Extracts
  62. Metabolic enzyme activities and drug excretion in the small intestine and in the liver in the rat
  63. (E)-2-benzylidenebenzocyclanones: Part X. Determination of logPof (E)-3-benzylidene-2,3-dihydro-1-benzopyran-4-ones by RP-TLC. Effect on logPof incorporation of oxygen atom into carbocyclic chalcone analogues
  64. Cyclic chalcone analogue KRP6 as a potent modulator of cell proliferation: an in vitro study in HUVECs
  65. Effect of selected dimethylaminochalcones on some mitochondrial activities
  66. Investigation of drug metabolism in various segments of small intestine in the rat
  67. Investigation of Interaction of Some Chalcones and Cyclic Chalcone Analogues with Outer Mitochondrial Membrane by UV-VIS and Fluorescence Spectroscopy
  68. Anti-angiogenic activity of the flavonoid precursor 4-hydroxychalcone
  69. (E)-2-Benzylidenebenzocyclanones: Part VII. Investigation of the conjugation reaction of two cytotoxic cyclic chalcone analogues with glutathione: an HPLC–MS study
  70. Difficulties and perspectives of immunomodulatory therapy with mistletoe lectins and standardized mistletoe extracts in evidence based medicine
  71. Comparison of structure, logP and P388 cytotoxicity of some phenyl and ferrocenyl cyclic chalcone analogues. Application of RP-TLC for logP determination of the ferrocenyl analogues
  72. (E)-2-Benzylidenebenzocyclanones, part VIII: spectrophotometric determination of pK a values of some natural and synthetic chalcones and their cyclic analogues
  73. Effect ofUncariaandTabebuiaextracts on molecular epidemiological biomarkers in patients with colorectal cancer
  74. Structural studies of seven homoisoflavonoids, six thiohomoisoflavonoids, and four structurally related compounds
  75. Kinetic Analysis of Some Chalcones and Synthetic Chalcone Analogues on the Fenton-Reaction Initiated Deoxyribose Degradation Assay1
  76. (E)-2-Benzylidenecyclanones: Part VI. Solvent effect on the UV and fluorescence properties of some chalcones and their cyclic analogues. Interaction of 4-dimethylaminochalcones with bovine and human serum albumin: a UV–vis study
  77. Difficulties and Perspectives of Immunomodulatory Therapy with Mistletoe Lectins and Standardized Mistletoe Extracts in Evidence-Based Medicine
  78. HPLC Quantification of 4-Nitrophenol and its Conjugated Metabolites from Bile
  79. ChemInform Abstract: Synthesis and Structure of 2-Phenyl-4-aryl-3,4,5,6-tetrahydrobenzo(h) quinazolines.
  80. ChemInform Abstract: Reaction of Benzylidenebenzocyclanones with Dithiocarbamic Acid and Thiourea.
  81. In vitro antiproliferative and antiangiogenic effects of synthetic chalcone analogues
  82. Production of Orally Applicable New Drug or Drug Combinations from Natural Origin Capsaicinoids for Human Medical Therapy
  83. Activation of oxidative stress response by hydroxyl substituted chalcones and cyclic chalcone analogues in mitochondria
  84. Some fluorescence properties of dimethylaminochalcone and its novel cyclic analogues
  85. Interdisciplinary review for correlation between the plant origin capsaicinoids, non-steroidal antiinflammatory drugs, gastrointestinal mucosal damage and prevention in animals and human beings
  86. Assessment of the effect of cyclic chalcone analogues on mitochondrial membrane and DNA
  87. Design, synthesis and antiproliferative activity of some 3-benzylidene-2,3-dihydro-1-benzopyran-4-ones which display selective toxicity for malignant cells
  88. Mechanistic investigations on the antioxidant action of a neuroprotective estrogen derivative
  89. Structure-to-activity studies of chemopreventive and tumor cell cytotoxic effects of chalcones and cyclic chalcone analogues
  90. 412 POSTER Antiangiogenic effect of newly synthesized chalcones
  91. UV and fluorescence characteristics of chalcone, 4-methoxy- and 4-dimethylaminochalcones and its cyclic analogues: Effect of structure and solvent
  92. Application of crocin bleaching and deoxyribose degradation tests to assess antioxidant capacity of capsaicinoids and some selected flavonoids
  93. Unexpected Different Binding of Mistletoe Lectins from Plant Extracts to Immobilized Lactose and N-acetylgalactosamine
  94. Different effects of two cyclic chalcone analogues on cell cycle of Jurkat T cells
  95. Comparison of the effects of selected chalcones, dihydrochalcones and some cyclic flavonoids on mitochondrial outer membrane determined by fluorescence spectroscopy
  96. A simple and rapid ion-pair HPLC method for simultaneous quantitation of 4-nitrophenol and its glucuronide and sulfate conjugates
  97. Use of RP-TLC for determination of logPof isomeric chalcones and cyclic chalcone analogues
  98. Mechanistic insights into the direct antioxidant effects of estrogens
  99. In-Solution and On-Plate Light-Catalyzed E/Z Isomerization of Cyclic Chalcone Analogues. Lipophilicity of E- and Z-2-(X-Benzylidene)-1-Benzosuberones
  100. E-2-Benzylidenebenzocycloalkanones. IV. Studies on transmission of substituent effects on 13C NMR chemical shifts of E-2-(X-benzylidene)-1-tetralones, and -benzosuberones. Comparison with the 13C NMR data of chalcones and E-2-(X-benzylidene)-1-indanones
  101. Centrally Acting and Metabolically Stable Thyrotropin-Releasing Hormone Analogues by Replacement of Histidine with Substituted Pyridinium
  102. Comparison of effect of selected synthetic chalcone analogues on mitochondrial outer membrane determined by fluorescence spectroscopy
  103. E-2-Benzylidenebenzocycloalkanones III. Studies on transmission of substituent effects on IR carbonyl stretching frequencies and 13C NMR chemical shifts of E-2-(X-benzylidene)-1-indanones. Comparison with the IR data of E-2-(X-benzylidene)-1-indanones,...
  104. E-2-Benzylidenebenzocycloalkanones III. Studies on transmission of substituent effects on IR carbonyl stretching frequencies and 13C NMR chemical shifts of E-2-(X-benzylidene)-1-indanones. Comparison with the IR data of E-2-(X-benzylidene)-1-indanones,...
  105. Quinol-based cyclic antioxidant mechanism in estrogen neuroprotection
  106. Determination of clodronate content in liposomal formulation by capillary zone electrophoresis
  107. A study on CYP1A inhibitory action of E-2-(4′-methoxybenzylidene)-1-benzosuberone and some related chalcones and cyclic chalcone analogues
  108. Design, synthesis, and biological evaluation of novel, centrally-Acting thyrotropin-Releasing hormone analogues
  109. Correlations between Cytotoxicity and Topography of Some 2-Arylidenebenzocycloalkanones Determined by X-ray Crystallography
  110. 2-(2,4-Dichlorophenylmethylene)-1-tetralone
  111. 2-(2,4-Dichlorophenylhydroxymethyl)-1-tetralone
  112. Integration of mass spectrometry into early-phase discovery and development of central nervous system agents
  113. Study on Ferrocenes, Part 7. E -2-Ferrocenemethylene-1-benzocyclanones. Synthesis, stereostructure, NMR, IR X-ray, and Mössbauer spectroscopic investigation
  114. E-2-benzylidenebenzocyclanones. II. IR and mass spectrometric investigations
  115. Conformational and Quantitative Structure−Activity Relationship Study of Cytotoxic 2-Arylidenebenzocycloalkanones
  116. E -2-Benzylidenebenzocycloalkanones. Stereostructure and NMR spectroscopic investigation
  117. Enhancement of selenium excretion in bile by sulfobromophthalein: elucidation of the mechanism
  118. Role of glutathione and methylation in the biliary excretion of selenium. the paradoxical effect of sulfobromophthalein
  119. Selenite metabolites react in vivo with sulfobromophthalein (BSP)to form cholephiuc BSP-Se metabolites
  120. Glutathione-dependent biliary excretion of selenium is enhanced paradoxically by sulfobromophthalein
  121. Benzylideneindanones and Benzylidenebenzosuberones: Relationship between Structure, Antimycotic Activity and Acute Toxicity
  122. Synthesis, structure and conformational analysis of imidazo-thiazines
  123. Synthesis, structure and conformational analysis of imidazo-thiazines
  124. Reaction of benzylidenebenzocyclanones with dithiocarbamic acid and thiourea
  125. Relationship between Dominant Conformation and Diastereoselectivity ofO-Acetal Formation of Saturated 2H-3,1-Benzothiazine-2-thiones
  126. Synthesis and structure of 2-phenyl-4-aryl-3,4,5,6-tetrahydrobenzo[h]quinazolines
  127. Transmission of substituent effects through unsaturated systems Part 71. Influence of substituent on infrared and 13C NMR properties in rigid cisoid and transoid Conformations of α-enones
  128. Synthesis of partially saturated N-substituted 4H-3,1-benzothiazine-2(1H)-thiones
  129. ChemInform Abstract: Synthesis and Stereochemistry of Saturated and Partially Saturated 4-Aryl-4H-3,1-benzothiazine-2(1H)-thiones.
  130. Synthesis and Stereochemistry of Saturated and Partially Saturated 4-Aryl-4H-3,1-benzothiazine-2(1H)-thiones
  131. Structure of (2R*,8R*)-2-[α-(thiocarbamoylthio)benzyl]indan-1-one
  132. ChemInform Abstract: Reaction of Cyclic Thioureas with 2-Benzylidene/Cycloalkanones.
  133. Reaction of Cyclic Thioureas with 2-Benzylidenecycloalkanones
  134. ChemInform Abstract: The Stereochemistry of Reaction of 2-Benzylidenecyclohexanone with Dithiocarbamic Acid.
  135. Structure of 7a-hydroxy-4-phenyl-1,2,4,4a,5,6,7,7a-octahydrocyclopenta[d][1,3]thiazine-2-thione
  136. ChemInform Abstract: Synthesis of 4,6-Diaryl-2,3-dihydro-6H-1,3-thiazine-2-thiones by the Reaction of Chalcones with Dithiocarbamic Acid.
  137. The stereochemistry of reaction of 2-benzylidenecyclohexanone with dithiocarbamic acid