All Stories

  1. Reversible Active Site Sulfoxygenation Can Explain the Oxygen Tolerance of a NAD + -Reducing [NiFe] Hydrogenase and Its Unusual Infrared Spectroscopic Properties

    Article • Journal of the American Chemical Society, February 2015, American Chemical Society (ACS)

    Dr Oliver Lenz

  2. Impact of the Iron–Sulfur Cluster Proximal to the Active Site on the Catalytic Function of an O 2 -Tolerant NAD + -Reducing [NiFe]-Hydrogenase

    Article • Biochemistry, January 2015, American Chemical Society (ACS)

    Dr Oliver Lenz, Dr Lars Lauterbach

  3. Nuclear resonance vibrational spectroscopy reveals the FeS cluster composition and active site vibrational properties of an O2-tolerant NAD+-reducing [NiFe] hydrogenase

    Article • Chemical Science, January 2015, Royal Society of Chemistry

    Dr Lars Lauterbach, Dr Oliver Lenz

  4. Resonance Raman Spectroscopy on [NiFe] Hydrogenase Provides Structural Insights into Catalytic Intermediates and Reactions

    Article • Journal of the American Chemical Society, July 2014, American Chemical Society (ACS)

    Dr Oliver Lenz

  5. Enhanced Oxygen-Tolerance of the Full Heterotrimeric Membrane-Bound [NiFe]-Hydrogenase of Ralstonia eutropha

    Article • Journal of the American Chemical Society, June 2014, American Chemical Society (ACS)

    Dr Oliver Lenz

  6. Reversible [4Fe-3S] cluster morphing in an O2-tolerant [NiFe] hydrogenase

    Article • Nature Chemical Biology, April 2014, Springer Science + Business Media

    Dr Oliver Lenz

  7. Crystal structure of an O2-tolerant [NiFe]-hydrogenase from Ralstonia eutropha in its as-isolated form - oxidized state 1

    Article • April 2014, Protein Data Bank, Rutgers University

    Dr Oliver Lenz

  8. Crystal structure of an O2-tolerant [NiFe]-hydrogenase from Ralstonia eutropha in its as-isolated form with ascorbate - partly reduced state

    Article • April 2014, Protein Data Bank, Rutgers University

    Dr Oliver Lenz

  9. Crystal structure of an O2-tolerant [NiFe]-hydrogenase from Ralstonia eutropha in its as-isolated form - oxidized state 2

    Article • April 2014, Protein Data Bank, Rutgers University

    Dr Oliver Lenz

  10. Rubredoxin-related Maturation Factor Guarantees Metal Cofactor Integrity during Aerobic Biosynthesis of Membrane-bound [NiFe] Hydrogenase

    Article • Journal of Biological Chemistry, January 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Lenz

  11. Stability enhancement of an O2-tolerant NAD+-reducing [NiFe]-hydrogenase by a combination of immobilisation and chemical modification

    Article • Journal of Molecular Catalysis B Enzymatic, December 2013, Elsevier

    Dr Lars Lauterbach, Professor Marion B. Ansorge-Schumacher, Dr Oliver Lenz

  12. Catalytic Production of Hydrogen Peroxide and Water by Oxygen-Tolerant [NiFe]-Hydrogenase during H2 Cycling in the Presence of O2

    Article • Journal of the American Chemical Society, November 2013, American Chemical Society (ACS)

    Dr Lars Lauterbach, Dr Oliver Lenz

  13. Novel, Oxygen-Insensitive Group 5 [NiFe]-Hydrogenase in Ralstonia eutropha

    Article • Applied and Environmental Microbiology, June 2013, ASM Journals

    Dr Oliver Lenz

  14. Attenuated total reflectance infrared spectroelectrochemistry at a carbon particle electrode; unmediated redox control of a [NiFe]-hydrogenase solution

    Article • Physical Chemistry Chemical Physics, January 2013, Royal Society of Chemistry

    Dr Oliver Lenz

  15. A Universal Scaffold for Synthesis of the Fe(CN)2(CO) Moiety of [NiFe] Hydrogenase

    Article • Journal of Biological Chemistry, September 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Lenz

  16. Stabilisation of the NAD+-reducing soluble [NiFe]-hydrogenase from Ralstonia eutropha H16 through modification with methoxy-poly(ethylene) glycol

    Article • Journal of Molecular Catalysis B Enzymatic, February 2012, Elsevier

    Dr Lars Lauterbach, Professor Marion B. Ansorge-Schumacher, Dr Oliver Lenz

  17. A modular system for regeneration of NADcofactors using graphite particles modified with hydrogenase and diaphorase moieties

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Dr Lars Lauterbach, Dr Oliver Lenz

  18. A Trimeric Supercomplex of the Oxygen-Tolerant Membrane-Bound [NiFe]-Hydrogenase from Ralstonia eutropha H16

    Article • Biochemistry, December 2011, American Chemical Society (ACS)

    Dr Oliver Lenz

  19. Probing the Origin of the Metabolic Precursor of the CO Ligand in the Catalytic Center of [NiFe] Hydrogenase

    Article • Journal of Biological Chemistry, November 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Lenz

  20. The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre

    Article • Nature, October 2011, Springer Science + Business Media

    Dr Oliver Lenz

  21. Catalytic Properties of the Isolated Diaphorase Fragment of the NAD+-Reducing [NiFe]-Hydrogenase from Ralstonia eutropha

    Article • PLoS ONE, October 2011, PLOS

    Dr Lars Lauterbach, Dr Oliver Lenz

  22. Systematic evaluation of the dihydrogen-oxidising and NAD+-reducing soluble [NiFe]-hydrogenase from Ralstonia eutropha H16 as a cofactor regeneration catalyst

    Article • Biocatalysis and Biotransformation, September 2011, Taylor & Francis

    Dr Lars Lauterbach, Professor Marion B. Ansorge-Schumacher, Dr Oliver Lenz

  23. Erratum: A unique iron-sulfur cluster is crucial for oxygen tolerance of a [NiFe]-hydrogenase

    Article • Nature Chemical Biology, August 2011, Springer Science + Business Media

    Dr Matthias Stein, Dr Oliver Lenz

  24. Erratum: A unique iron-sulfur cluster is crucial for oxygen tolerance of a [NiFe]-hydrogenase

    Article • Nature Chemical Biology, August 2011, Springer Science + Business Media

    Dr Matthias Stein, Dr Oliver Lenz

  25. [NiFe] and [FeS] Cofactors in the Membrane-Bound Hydrogenase of Ralstonia eutropha Investigated by X-ray Absorption Spectroscopy: Insights into O 2 -Tolerant H 2 Cleavage

    Article • Biochemistry, July 2011, American Chemical Society (ACS)

    Dr Matthias Stein, Dr Oliver Lenz

  26. The Maturation Factors HoxR and HoxT Contribute to Oxygen Tolerance of Membrane-Bound [NiFe] Hydrogenase in Ralstonia eutropha H16

    Article • Journal of Bacteriology, March 2011, ASM Journals

    Dr Oliver Lenz

  27. A unique iron-sulfur cluster is crucial for oxygen tolerance of a [NiFe]-hydrogenase

    Article • Nature Chemical Biology, March 2011, Springer Science + Business Media

    Dr Matthias Stein, Dr Oliver Lenz

  28. The Hydrogenase Subcomplex of the NAD+‐Reducing [NiFe] Hydrogenase from Ralstonia eutropha – Insights into Catalysis and Redox Interconversions

    Article • European Journal of Inorganic Chemistry, February 2011, Wiley

    Dr Lars Lauterbach, Dr Oliver Lenz

  29. Untersuchung des katalytischen Zentrums der O2‐toleranten NAD+‐reduzierenden [NiFe]‐Hydrogenase von Ralstonia eutropha H16 mit In‐situ‐EPR‐ und ‐FTIR‐Spektroskopie

    Article • Angewandte Chemie, September 2010, Wiley

    Dr Lars Lauterbach, Dr Oliver Lenz

  30. Probing the Active Site of an O2‐Tolerant NAD+‐Reducing [NiFe]‐Hydrogenase from Ralstonia eutropha H16 by In Situ EPR and FTIR Spectroscopy

    Article • Angewandte Chemie International Edition, September 2010, Wiley

    Dr Lars Lauterbach, Dr Oliver Lenz

  31. Protein-Protein Complex Formation Affects the Ni-Fe and Fe-S Centers in the H2-Sensing Regulatory Hydrogenase from Ralstonia eutropha H16

    Article • ChemPhysChem, April 2010, Wiley

    Dr Matthias Stein, Dr Oliver Lenz

  32. Impact of Amino Acid Substitutions near the Catalytic Site on the Spectral Properties of an O2-Tolerant Membrane-Bound [NiFe] Hydrogenase

    Article • ChemPhysChem, April 2010, Wiley

    Dr Oliver Lenz

  33. H2 Conversion in the Presence of O2 as Performed by the Membrane-Bound [NiFe]-Hydrogenase of Ralstonia eutropha

    Article • ChemPhysChem, April 2010, Wiley

    Dr Oliver Lenz

  34. Requirements for Construction of a Functional Hybrid Complex of Photosystem I and [NiFe]-Hydrogenase

    Article • Applied and Environmental Microbiology, February 2010, ASM Journals

    Dr Oliver Lenz

  35. Photosynthetic Hydrogen Production by a Hybrid Complex of Photosystem I and [NiFe]-Hydrogenase

    Article • ACS Nano, December 2009, American Chemical Society (ACS)

    Dr Oliver Lenz

  36. Spectroscopic Insights into the Oxygen-tolerant Membrane-associated [NiFe] Hydrogenase of Ralstonia eutropha H16

    Article • Journal of Biological Chemistry, March 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Lenz

  37. Untersuchung des Katalyseprozesses der membrangebundenen Hydrogenase ausRalstonia eutrophaH16 mittels oberflächenverstärkter IR-Absorptionsspektroskopie

    Article • Angewandte Chemie, January 2009, Wiley

    Dr Oliver Lenz

  38. Monitoring Catalysis of the Membrane-Bound Hydrogenase fromRalstonia eutrophaH16 by Surface-Enhanced IR Absorption Spectroscopy

    Article • Angewandte Chemie International Edition, January 2009, Wiley

    Dr Oliver Lenz

  39. Concerted Action of Two Novel Auxiliary Proteins in Assembly of the Active Site in a Membrane-bound [NiFe] Hydrogenase

    Article • Journal of Biological Chemistry, November 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Lenz

  40. Chaperones specific for the membrane‐bound [NiFe]‐hydrogenase interact with the Tat signal peptide of the small subunit precursor in Ralstonia eutropha H16

    Article • Molecular Microbiology, September 2007, Wiley

    Dr Oliver Lenz

  41. Carbamoylphosphate serves as the source of CN−, but not of the intrinsic CO in the active site of the regulatory [NiFe]-hydrogenase fromRalstonia eutropha

    Article • FEBS Letters, June 2007, Wiley

    Dr Oliver Lenz

  42. Electricity from low-level H2 in still air ? an ultimate test for an oxygen tolerant hydrogenase

    Article • Chemical Communications, January 2006, Royal Society of Chemistry

    Dr Oliver Lenz

  43. Light-driven Hydrogen Production by a Hybrid Complex of a [NiFe]-Hydrogenase and the Cyanobacterial Photosystem I

    Article • Photochemistry and Photobiology, January 2006, Wiley

    Dr Oliver Lenz

  44. Requirements for Heterologous Production of a Complex Metalloenzyme: the Membrane-Bound [NiFe] Hydrogenase

    Article • Journal of Bacteriology, September 2005, ASM Journals

    Dr Oliver Lenz

  45. A model system for [NiFe] hydrogenase maturation studies: Purification of an active site-containing hydrogenase large subunit without small subunit

    Article • FEBS Letters, July 2005, Wiley

    Dr Oliver Lenz

  46. Oxygen Tolerance of the H 2 -sensing [NiFe] Hydrogenase from Ralstonia eutropha H16 Is Based on Limited Access of Oxygen to the Active Site

    Article • Journal of Biological Chemistry, April 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Oliver Lenz

  47. NiFe Hydrogenase Active Site Biosynthesis:  Identification of Hyp Protein Complexes in Ralstonia eutropha †

    Article • Biochemistry, October 2004, American Chemical Society (ACS)

    Dr Oliver Lenz

  48. The H2-sensing complex of Ralstonia eutropha: interaction between a regulatory [NiFe] hydrogenase and a histidine protein kinase

    Article • Molecular Microbiology, February 2004, Wiley

    Dr Oliver Lenz

  49. Regulation of hydrogenase gene expression

    Article • November 2001, Taylor & Francis

    Dr Oliver Lenz