All Stories

  1. Models of depression for preclinical drug discovery and development: an update of the literature

    Article • Expert Opinion on Drug Discovery, August 2026, Taylor & Francis

    Dr Nikolaos Kokras

  2. Mental health and gut-brain crosstalk: implications for depression and Alzheimer’s disease

    Article • Neuroscience Applied, July 2026, Elsevier

    Dr Nikolaos Kokras

  3. Pharmacokinetics and pharmacodynamics: making clinical sense of sex differences in psychopharmacology

    Article • Expert Opinion on Drug Metabolism & Toxicology, November 2025, Taylor & Francis

    Dr Nikolaos Kokras

  4. Drug-drug interactions between COVID-19 drug therapies and antidepressants.

    Article • Expert Opinion on Drug Metabolism & Toxicology, November 2023, Taylor & Francis

    Dr Nikolaos Kokras

  5. Off-Target Effects of Antidepressants on Vascular Function and Structure

    Article • Biomedicines, December 2021, MDPI AG

    Dr Nikolaos Kokras

  6. Innovative screening models for the discovery of new schizophrenia drug therapies: an integrated approach

    Article • Expert Opinion on Drug Discovery, January 2021, Taylor & Francis

    Dr Nikolaos Kokras

  7. Detrimental effects of adolescent escalating low‐dose Δ 9 ‐tetrahydrocannabinol lead to a specific bio‐behavioural profile in adult male rats

    Article • British Journal of Pharmacology, January 2021, Wiley

    Dr Nikolaos Kokras

  8. Mesocorticolimbic monoamines in a rodent model of chronic neuropathic pain

    Article • Neuroscience Letters, August 2020, Elsevier

    Dr Nikolaos Kokras

  9. Do corticosterone levels predict female depressive‐like behavior in rodents?

    Article • Journal of Neuroscience Research, July 2020, Wiley

    Dr Nikolaos Kokras

  10. Sex Matters in Neuroscience and Neuropsychopharmacology

    Article • European Journal of Neuroscience, June 2020, Wiley

    Dr Nikolaos Kokras

  11. Allosteric modulation of AMPA receptors counteracts Tau-related excitotoxic synaptic signaling and memory deficits in stress- and Aβ-evoked hippocampal pathology

    Article • Molecular Psychiatry, May 2020, Springer Science + Business Media

    Dr Nikolaos Kokras

  12. Effect of sertraline on central serotonin and hippocampal plasticity in pregnant and non-pregnant rats

    Article • Neuropharmacology, January 2020, Elsevier

    Dr Nikolaos Kokras

  13. A novel UHPLC-HRMS-based metabolomics strategy enables the discovery of potential neuroactive metabolites in mice plasma, following i.p. administration of the main Crocus sativus L. bioactive component

    Article • Journal of Pharmaceutical and Biomedical Analysis, January 2020, Elsevier

    Dr Nikolaos Kokras

  14. Escalating low‐dose Δ 9 ‐tetrahydrocannabinol exposure during adolescence induces differential behavioral and neurochemical effects in male and female adult rats

    Article • European Journal of Neuroscience, November 2019, Wiley

    Dr Nikolaos Kokras

  15. The effect of treatment response on endothelial function and arterial stiffness in depression. A prospective study

    Article • Journal of Affective Disorders, June 2019, Elsevier

    Dr Nikolaos Kokras

  16. Sex differences in the HPA axis: an obstacle to antidepressant drug development?

    Article • British Journal of Pharmacology, May 2019, Wiley

    Dr Nikolaos Kokras

  17. Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fields

    Article • Translational Psychiatry, April 2019, Springer Science + Business Media

    Dr Nikolaos Kokras

  18. Women’s Psychiatry

    Article • January 2019, Springer Science + Business Media

    Dr Nikolaos Kokras

  19. Neuroplasticity-related correlates of environmental enrichment combined with physical activity differ between the sexes

    Article • European Neuropsychopharmacology, November 2018, Elsevier

    Dr Nikolaos Kokras

  20. Trans-crocin 4 is not hydrolyzed to crocetin following i.p. administration in mice, while it shows penetration through the blood brain barrier

    Article • Fitoterapia, June 2018, Elsevier

    Dr Nikolaos Kokras

  21. Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimerʼs Disease

    Article • Journal of Clinical Psychopharmacology, April 2018, Wolters Kluwer Health

    Dr Nikolaos Kokras

  22. Sex differences in behavioral and neurochemical effects of gonadectomy and aromatase inhibition in rats

    Article • Psychoneuroendocrinology, January 2018, Elsevier

    Dr Nikolaos Kokras

  23. Perinatal fluoxetine effects on social play, the HPA system, and hippocampal plasticity in pre-adolescent male and female rats: Interactions with pre-gestational maternal stress

    Article • Psychoneuroendocrinology, October 2017, Elsevier

    Dr Nikolaos Kokras

  24. Perinatal fluoxetine prevents the effect of pre-gestational maternal stress on 5-HT in the PFC, but maternal stress has enduring effects on mPFC synaptic structure in offspring

    Article • Neuropharmacology, October 2017, Elsevier

    Dr Nikolaos Kokras

  25. Personality characteristics and individual factors associated with PTSD in firefighters one month after extended wildfires

    Article • Nordic Journal of Psychiatry, September 2017, Taylor & Francis

    Dr Nikolaos Kokras

  26. Effect of Levodopa on Reward and Impulsivity in a Rat Model of Parkinson’s Disease

    Article • Frontiers in Behavioral Neuroscience, August 2017, Frontiers

    Dr Nikolaos Kokras

  27. Kinoscope: An Open-Source Computer Program for Behavioral Pharmacologists

    Article • Frontiers in Behavioral Neuroscience, May 2017, Frontiers

    Dr Nikolaos Kokras

  28. The nucleus reuniens: a key node in the neurocircuitry of stress and depression

    Article • Molecular Psychiatry, April 2017, Nature

    Dr Nikolaos Kokras

  29. Head shaking in the forced swim test: A robust but unexplored sex difference

    Article • Pharmacology Biochemistry and Behavior, January 2017, Elsevier

    Dr Nikolaos Kokras

  30. Preclinical sex differences in depression and antidepressant response: Implications for clinical research

    Article • Journal of Neuroscience Research, November 2016, Wiley

    Dr Nikolaos Kokras

  31. Gestational stress and fluoxetine treatment differentially affect plasticity, methylation and serotonin levels in the PFC and hippocampus of rat dams

    Article • Neuroscience, July 2016, Elsevier

    Dr Nikolaos Kokras

  32. Tau protein is essential for stress-induced brain pathology

    Article • Proceedings of the National Academy of Sciences, June 2016, Proceedings of the National Academy of Sciences

    Dr Nikolaos Kokras

  33. Forced swim test: What about females?

    Article • Neuropharmacology, December 2015, Elsevier

    Dr Nikolaos Kokras

  34. Developmental fluoxetine and prenatal stress effects on serotonin, dopamine, and synaptophysin density in the PFC and hippocampus of offspring at weaning

    Article • Developmental Psychobiology, October 2015, Wiley

    Dr Nikolaos Kokras

  35. Stress induced risk-aversion is reverted by D2/D3 agonist in the rat

    Article • European Neuropsychopharmacology, October 2015, Elsevier

    Dr Nikolaos Kokras, Pedro Morgado

  36. The positive effect on ketamine as a priming adjuvant in antidepressant treatment

    Article • Translational Psychiatry, May 2015, Nature

    Dr Nikolaos Kokras

  37. Sex differences in animal models of psychiatric disorders

    Article • British Journal of Pharmacology, July 2014, Wiley

    Dr Nikolaos Kokras

  38. Acute but not sustained aromatase inhibition displays antidepressant properties

    Article • The International Journal of Neuropsychopharmacology, March 2014, Oxford University Press (OUP)

    Dr Nikolaos Kokras

  39. Psychological but not vasomotor symptoms are associated with temperament and character traits

    Article • Climacteric, March 2014, Taylor & Francis

    Dr Nikolaos Kokras

  40. Increased co-morbidity of depression and post-traumatic stress disorder symptoms and common risk factors in intensive care unit survivors: A two-year follow-up study

    Article • International Journal of Psychiatry in Clinical Practice, January 2014, Taylor & Francis

    Dr Nikolaos Kokras

  41. Sex-dependent neurochemical effects of environmental enrichment in the visual system

    Article • Neuroscience, December 2013, Elsevier

    Dr Nikolaos Kokras

  42. A Severe and Irreversible Case of Tardive Rigid-Akinetic Parkinsonian Syndrome

    Article • Journal of Psychiatric Practice, September 2013, Wolters Kluwer Health

    Dr Nikolaos Kokras

  43. Pharmacogenetic considerations for late life depression therapy

    Article • Expert Opinion on Drug Metabolism & Toxicology, May 2013, Informa Healthcare

    Dr Nikolaos Kokras

  44. Experimental Evidence for Sildenafil's Action in the Central Nervous System: Dopamine and Serotonin Changes in the Medial Preoptic Area and Nucleus Accumbens During Sexual Arousal

    Article • The Journal of Sexual Medicine, March 2013, Elsevier

    Dr Nikolaos Kokras

  45. Neudesin is involved in anxiety behavior: structural and neurochemical correlates

    Article • Frontiers in Behavioral Neuroscience, January 2013, Frontiers

    Dr Nikolaos Kokras

  46. Dysfunctional remembered parenting in oncology outpatients affects psychological distress symptoms in a gender-specific manner

    Article • Stress and Health, October 2012, Wiley

    Dr Nikolaos Kokras

  47. Sertraline behavioral response associates closer and dose-dependently with cortical rather than hippocampal serotonergic activity in the rat forced swim stress

    Article • Physiology & Behavior, September 2012, Elsevier

    Dr Nikolaos Kokras

  48. Behavioral sexual dimorphism in models of anxiety and depression due to changes in HPA axis activity

    Article • Neuropharmacology, January 2012, Elsevier

    Dr Nikolaos Kokras

  49. Citalopram-mediated anxiolysis and differing neurobiological responses in both sexes of a genetic model of depression

    Article • Neuroscience, October 2011, Elsevier

    Dr Nikolaos Kokras

  50. Cardiac Rhythm Management Devices and Electroconvulsive Therapy

    Article • Journal of Ect, September 2011, Wolters Kluwer Health

    Dr Nikolaos Kokras

  51. Predicting insomnia in medical wards: the effect of anxiety, depression and admission diagnosis

    Article • General Hospital Psychiatry, January 2011, Elsevier

    Dr Nikolaos Kokras

  52. Sex differences in pharmacokinetics of antidepressants

    Article • Expert Opinion on Drug Metabolism & Toxicology, December 2010, Informa Healthcare

    Dr Nikolaos Kokras

  53. Sex Differences in Animal Models of Depression and Antidepressant Response

    Article • Basic & Clinical Pharmacology & Toxicology, March 2010, Wiley

    Dr Nikolaos Kokras

  54. Bupropion-Induced Sleepwalking

    Article • Journal of Clinical Psychopharmacology, February 2010, Wolters Kluwer Health

    Dr Nikolaos Kokras

  55. Sex Differences in Response to Stress and Expression of Depressive-Like Behaviours in the Rat

    Article • January 2010, Springer Science + Business Media

    Dr Nikolaos Kokras

  56. Adjunctive Low-Dose Amisulpride in Motor Conversion Disorder

    Article • Clinical Neuropharmacology, November 2009, Wolters Kluwer Health

    Dr Nikolaos Kokras

  57. Antidepressants induce regionally discrete, sex-dependent changes in brain's glutamate content

    Article • Neuroscience Letters, October 2009, Elsevier

    Dr Nikolaos Kokras

  58. Sex-related differential response to clomipramine treatment in a rat model of depression

    Article • Journal of Psychopharmacology, August 2008, SAGE Publications

    Dr Nikolaos Kokras

  59. Sex differences in the effects of two stress paradigms on dopaminergic neurotransmission

    Article • Physiology & Behavior, February 2008, Elsevier

    Dr Nikolaos Kokras

  60. Chronic mild stress impact: Are females more vulnerable?

    Article • Neuroscience, January 2005, Elsevier

    Dr Nikolaos Kokras