All Stories

  1. Development of a disease-specific health utility score for chronic obstructive pulmonary disease from a discrete choice experiment patient preference study

    Article • International Journal of Technology Assessment in Health Care, January 2024, Cambridge University Press

    Nigel Cook

  2. People living with moderate-to-severe COPD prefer improvement of daily symptoms over the improvement of exacerbations: a multicountry patient preference study

    Article • ERJ Open Research, April 2022, European Respiratory Society (ERS)

    Nigel Cook

  3. Development of an international template to support patient submissions in Health Technology Assessments

    Article • International Journal of Technology Assessment in Health Care, January 2021, Cambridge University Press

    Nigel Cook

  4. How to integrate evidence from patient preference studies into health technology assessment: a critical review and recommendations

    Article • International Journal of Technology Assessment in Health Care, January 2021, Cambridge University Press

    Nigel Cook

  5. Identification of Patient Needs and Preferences in Pigmented Villonodular Synovitis (PVNS) Using a Qualitative Online Bulletin Board Study

    Article • Advances in Therapy, May 2020, Springer Science + Business Media

    Nigel Cook

  6. Assessing physician preferences on future therapeutic options and diagnostic practices in non-alcoholic steatohepatitis

    Article • JHEP Reports, April 2020, Elsevier

    Nigel Cook

  7. Defining the needs and preferences of patients with dry eye disease

    Article • BMJ Open Ophthalmology, December 2019, BMJ

    Nigel Cook

  8. Comparing the needs and preferences of patients with moderate and severe dry eye symptoms across four countries

    Article • BMJ Open Ophthalmology, December 2019, BMJ

    Nigel Cook

  9. Patient Preferences in the Medical Product Lifecycle

    Article • The Patient Patient-Centered Outcomes Research, November 2019, Springer Science + Business Media

    Nigel Cook

  10. Gathering Structured Patient Insight to Drive the PRO Strategy in COPD: Patient-Centric Drug Development from Theory to Practice

    Article • Advances in Therapy, November 2019, Springer Science + Business Media

    Nigel Cook

  11. Evaluating Patient Experiences in Dry Eye Disease Through Social Media Listening Research

    Article • Ophthalmology and Therapy, June 2019, Springer Science + Business Media

    Nigel Cook

  12. Impact of cough and mucus on COPD patients: primary insights from an exploratory study with an Online Patient Community

    Article • International Journal of Chronic Obstructive Pulmonary Disease, June 2019, Dove Medical Press

    Alex Mackay, Nigel Cook

  13. Patient Preference Studies During Early Drug Development: Aligning Stakeholders to Ensure Development Plans Meet Patient Needs

    Article • Frontiers in Medicine, April 2019, Frontiers

    Nigel Cook

  14. The Patient Perspectives on Future Therapeutic Options in NASH and Patient Needs

    Article • Frontiers in Medicine, April 2019, Frontiers

    Nigel Cook

  15. Patient Needs, Perceptions, and Attitudinal Drivers Associated with Obesity: A Qualitative Online Bulletin Board Study

    Article • Advances in Therapy, March 2019, Springer Science + Business Media

    Nigel Cook

  16. Patients' perspectives on COPD: findings from a social media listening study

    Article • ERJ Open Research, February 2019, European Respiratory Society (ERS)

    Nigel Cook

  17. Understanding Patient Preferences and Unmet Needs in Non-alcoholic Steatohepatitis (NASH): Insights from a Qualitative Online Bulletin Board Study

    Article • Advances in Therapy, December 2018, Springer Science + Business Media

    Nigel Cook

  18. PGI44 - PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH) REPORT POSITIVE EXPERIENCE AFTER PARTICIPATING IN AN ONLINE QUANTITATIVE PREFERENCE SURVEY

    Article • Value in Health, October 2018, Elsevier

    Nigel Cook

  19. PGI43 - WHAT DO PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH) VALUE AND NEED? RESULTS FROM A QUANTITATIVE PATIENT PREFERENCE STUDY

    Article • Value in Health, October 2018, Elsevier

    Nigel Cook

  20. The Role of Patients inMarket Access

    Article • January 2018, Seed SRL

    Nigel Cook

  21. Giving Patients’ Preferences a Voice in Medical Treatment Life Cycle: The PREFER Public–Private Project

    Article • The Patient Patient-Centered Outcomes Research, February 2017, Springer Science + Business Media

    Nigel Cook

  22. Heterogeneity in Relative Efficacy Assessments (Rea) across European Hta Bodies: Opportunity for Improving Efficiency and Speed of Access to Patients?

    Article • Value in Health, November 2015, Elsevier

    Nigel Cook

  23. Chronic graft loss: dealing with the vascular alterations in solid organ transplantation

    Article • Transplantation Proceedings, August 1998, Elsevier

    Nigel Cook

  24. Preclinical models of chronic rejection: promises and pitfalls

    Article • Transplantation Proceedings, September 1997, Elsevier

    Nigel Cook

  25. Beta-amino acid derivatives as orally active non-peptide fibrinogen receptor antagonists

    Article • Bioorganic & Medicinal Chemistry Letters, March 1997, Elsevier

    Nigel Cook

  26. THROMBIN INHIBITION IN AN EX VIVO MODEL OF PORCINE HEART XENOGRAFT HYPERACUTE REJECTION1

    Article • Transplantation, March 1996, Wolters Kluwer Health

    Nigel Cook

  27. Inhibition of platelet GPIIbIa in an ex vivo model of hyperacute xenograft rejection does not prolong cardiac survival time

    Article • Xenotransplantation, February 1996, Wiley

    Nigel Cook

  28. Pharmacological inhibition of restenosis: learning from experience

    Article • Trends in Pharmacological Sciences, December 1995, Elsevier

    Nigel Cook

  29. Decreased lumen size after balloon injury despite inhibition of neointimal thickening and antivasospastic treatment

    Article • Cardiovascular Research, February 1994, European Society of Cardiology

    Nigel Cook

  30. Structure and function of thrombin receptors

    Article • Trends in Pharmacological Sciences, December 1993, Elsevier

    Nigel Cook

  31. Synthetic low-molecular weight thrombin inhibitors: molecular design and pharmacological profile

    Article • Trends in Pharmacological Sciences, October 1993, Elsevier

    Nigel Cook

  32. Therapeutic potential of potassium channel openers in peripheral vascular disease and asthma

    Article • Cardiovascular Drugs and Therapy, August 1993, Springer Science + Business Media

    Nigel Cook

  33. Spirapril and Cilazapril Inhibit Neointimal Lesion Development but Cause no Detectable Inhibition of Lumen Narrowing After Carotid Artery Balloon Catheter Injury in the Rat

    Article • Blood Pressure, January 1993, Taylor & Francis

    Nigel Cook

  34. New developments in cardiovascular magnetic resonance imaging and spectroscopy

    Article • Trends in Pharmacological Sciences, January 1991, Elsevier

    Nigel Cook

  35. Angiotensin II can regulate gene expression by the AP-1 binding sequence via a protein kinase C-dependent pathway

    Article • Biochemical and Biophysical Research Communications, November 1990, Elsevier

    Nigel Cook

  36. Fibrinogen as a major risk factor in cardiovascular disease

    Article • Trends in Pharmacological Sciences, November 1990, Elsevier

    Nigel Cook

  37. Moving together: K+ channel openersand ATP-sensitive K+ channels

    Article • Trends in Pharmacological Sciences, November 1989, Elsevier

    Nigel Cook

  38. Anti-vasoconstrictor effects of the K+ channel opener cromakalim on the rabbit aorta-comparison with the calcium antagonist isradipine

    Article • British Journal of Pharmacology, November 1988, Wiley

    Nigel Cook

  39. Mechanism of action and systemic and regional hemodynamics of the potassium channel activator BRL34915 and its enantiomers.

    Article • Circulation Research, April 1988, Wolters Kluwer Health

    Nigel Cook

  40. PN 200–110, a Calcium Antagonist with High Potency and Selectivity for Vascular Smooth Muscle

    Article • Annals of the New York Academy of Sciences, March 1988, Wiley

    Nigel Cook

  41. Cardiovascular effects of apamin and BRL 34915 in rats and rabbits

    Article • British Journal of Pharmacology, January 1988, Wiley

    Nigel Cook

  42. Leiurus quinquestriatus venom inhibits BRL 34915-induced 86Rb+ efflux from the rat portal vein

    Article • Life Sciences, January 1988, Elsevier

    Nigel Cook

  43. Pertussis toxin treatment does not inhibit the effects of the potassium channel opener BRL 34915 on rat isolated vascular and cardiac tissues

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, January 1988, Springer Science + Business Media

    Nigel Cook

  44. The pharmacology of potassium channels and their therapeutic potential

    Article • Trends in Pharmacological Sciences, January 1988, Elsevier

    Nigel Cook

  45. Effects of the enantiomers of the dihydropyridine derivative 202–791 on contractility, coronary flow and ischemia-related arrhythmias in rat heart

    Article • European Journal of Pharmacology, April 1986, Elsevier

    Nigel Cook

  46. Cardioprotection by the calcium antagonist PN 200-110 in the absence and presence of cardiodepression

    Article • British Journal of Pharmacology, September 1985, Wiley

    Nigel Cook

  47. Effects of apamin, quinine and neuromuscular blockers on calcium-activated potassium channels in guinea-pig hepatocytes.

    Article • The Journal of Physiology, January 1985, Wiley

    Nigel Cook

  48. Calcium-activated potassium channels in liver cells

    Article • Cell Calcium, December 1983, Elsevier

    Nigel Cook

  49. High affinity binding of [125I]monoiodoapamin to isolated guinea-pig hepatocytes

    Article • FEBS Letters, February 1983, Wiley

    Nigel Cook