All Stories

  1. A Distinct Contractile Injection System Found in a Majority of Adult Human Microbiomes

    Article • December 2019, Cold Spring Harbor Laboratory Press

    Nicholas Shikuma

  2. A contractile injection system stimulates tubeworm metamorphosis by translocating a proteinaceous effector

    Article • eLife, September 2019, eLife

    Nicholas Shikuma

  3. A Bacterial Phage Tail-like Structure Kills Eukaryotic Cells by Injecting a Nuclease Effector

    Article • Cell Reports, July 2019, Elsevier

    Nicholas Shikuma

  4. Stepwise metamorphosis of the tubeworm Hydroides elegans is mediated by a bacterial inducer and MAPK signaling

    Article • Proceedings of the National Academy of Sciences, August 2016, Proceedings of the National Academy of Sciences

    Nicholas Shikuma

  5. Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids

    Article • PLoS ONE, March 2016, PLOS

    Dr Loni Townsley, Nicholas Shikuma

  6. Lipid remodeling inRhodopseudomonas palustris TIE-1upon loss of hopanoids and hopanoid methylation

    Article • Geobiology, April 2015, Wiley

    Nicholas Shikuma

  7. Marine Tubeworm Metamorphosis Induced by Arrays of Bacterial Phage Tail-Like Structures

    Article • Science, January 2014, American Association for the Advancement of Science

    Nicholas Shikuma

  8. The transcriptional regulator, CosR, controls compatible solute biosynthesis and transport, motility and biofilm formation inVibrio cholerae

    Article • Environmental Microbiology, June 2012, Wiley

    Nicholas Shikuma

  9. Cellular Levels and Binding of c-di-GMP Control Subcellular Localization and Activity of the Vibrio cholerae Transcriptional Regulator VpsT

    Article • PLoS Pathogens, May 2012, PLOS

    Nicholas Shikuma

  10. You’ve come a long way: c-di-GMP signaling

    Article • Current Opinion in Microbiology, April 2012, Elsevier

    Dr Holger Sondermann, Nicholas Shikuma

  11. An image-based 384-well high-throughput screening method for the discovery of biofilm inhibitors in Vibrio cholerae

    Article • Molecular BioSystems, January 2011, Royal Society of Chemistry

    Nicholas Shikuma

  12. Vibrio cholerae VpsT Regulates Matrix Production and Motility by Directly Sensing Cyclic di-GMP

    Article • Science, February 2010, American Association for the Advancement of Science

    Nicholas Shikuma

  13. Marine biofilms on submerged surfaces are a reservoir forEscherichia coliandVibrio cholerae

    Article • Biofouling, January 2010, Taylor & Francis

    Nicholas Shikuma

  14. Overexpression of VpsS, a Hybrid Sensor Kinase, Enhances Biofilm Formation in Vibrio cholerae

    Article • Journal of Bacteriology, June 2009, ASM Journals

    Nicholas Shikuma

  15. Identification and Characterization of OscR, a Transcriptional Regulator Involved in Osmolarity Adaptation in Vibrio cholerae

    Article • Journal of Bacteriology, March 2009, ASM Journals

    Nicholas Shikuma

  16. Temporal variation of an initial marine biofilm community and its effects on larval settlement and metamorphosis of the tubeworm Hydroides elegans

    Article • Biofilms, October 2005, Cambridge University Press

    Nicholas Shikuma