All Stories

  1. Decoding resistance in the age of T6SS warfare

    Article • Proceedings of the National Academy of Sciences, February 2025, Proceedings of the National Academy of Sciences

    Nicholas Shikuma

  2. A bacterial membrane-disrupting protein stimulates animal metamorphosis

    Article • mBio, February 2025, ASM Journals

    Nicholas Shikuma

  3. Linking bacterial tetrabromopyrrole biosynthesis to coral metamorphosis

    Article • ISME Communications, September 2023, Oxford University Press (OUP)

    Nicholas Shikuma

  4. A modular plasmid toolkit applied in marine bacteria reveals functional insights during bacteria-stimulated metamorphosis

    Article • mBio, August 2023, ASM Journals

    Nicholas Shikuma

  5. Future research directions of the model marine tubeworm Hydroides elegans and synthesis of developmental staging of the complete life cycle

    Article • Developmental Dynamics, May 2023, Wiley

    Nicholas Shikuma

  6. Diacylglycerol, PKC and MAPK signaling initiate tubeworm metamorphosis in response to bacteria

    Article • Developmental Biology, July 2022, Elsevier

    Nicholas Shikuma

  7. Draft Genome Sequence of Nereida sp. Strain MMG025, Isolated from Giant Kelp

    Article • Microbiology Resource Announcements, June 2022, ASM Journals

    Nicholas Shikuma

  8. Bacteria-Stimulated Metamorphosis: an Ocean of Insights from Investigating a Transient Host-Microbe Interaction

    Article • mSystems, August 2021, ASM Journals

    Nicholas Shikuma

  9. Draft Genome Sequences of 10 Bacteria from the Marine Pseudoalteromonas Group

    Article • Microbiology Resource Announcements, August 2021, ASM Journals

    Nicholas Shikuma

  10. Genetic examination of the marine bacterium Pseudoalteromonas luteoviolacea and effects of its metamorphosis‐inducing factors

    Article • Environmental Microbiology, September 2020, Wiley

    Nicholas Shikuma

  11. The Influence of Bacteria on Animal Metamorphosis

    Article • Annual Review of Microbiology, September 2020, Annual Reviews

    Nicholas Shikuma

  12. A Distinct Contractile Injection System Gene Cluster Found in a Majority of Healthy Adult Human Microbiomes

    Article • mSystems, July 2020, ASM Journals

    Dr Robert A Edwards, Nicholas Shikuma

  13. A Distinct Contractile Injection System Found in a Majority of Adult Human Microbiomes

    Article • December 2019, Cold Spring Harbor Laboratory Press

    Nicholas Shikuma, Dr Robert A Edwards

  14. A contractile injection system stimulates tubeworm metamorphosis by translocating a proteinaceous effector

    Article • eLife, September 2019, eLife

    Nicholas Shikuma

  15. A Bacterial Phage Tail-like Structure Kills Eukaryotic Cells by Injecting a Nuclease Effector

    Article • Cell Reports, July 2019, Elsevier

    Nicholas Shikuma

  16. Stepwise metamorphosis of the tubeworm Hydroides elegans is mediated by a bacterial inducer and MAPK signaling

    Article • Proceedings of the National Academy of Sciences, August 2016, Proceedings of the National Academy of Sciences

    Nicholas Shikuma

  17. Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids

    Article • PLOS One, March 2016, PLOS

    Dr Loni Townsley, Nicholas Shikuma

  18. Lipid remodeling inRhodopseudomonas palustris TIE-1upon loss of hopanoids and hopanoid methylation

    Article • Geobiology, April 2015, Wiley

    Nicholas Shikuma

  19. Marine Tubeworm Metamorphosis Induced by Arrays of Bacterial Phage Tail-Like Structures

    Article • Science, January 2014, American Association for the Advancement of Science

    Nicholas Shikuma

  20. The transcriptional regulator, CosR, controls compatible solute biosynthesis and transport, motility and biofilm formation inVibrio cholerae

    Article • Environmental Microbiology, June 2012, Wiley

    Nicholas Shikuma

  21. Cellular Levels and Binding of c-di-GMP Control Subcellular Localization and Activity of the Vibrio cholerae Transcriptional Regulator VpsT

    Article • PLoS Pathogens, May 2012, PLOS

    Nicholas Shikuma

  22. You’ve come a long way: c-di-GMP signaling

    Article • Current Opinion in Microbiology, April 2012, Elsevier

    Dr Holger Sondermann, Nicholas Shikuma

  23. An image-based 384-well high-throughput screening method for the discovery of biofilm inhibitors in Vibrio cholerae

    Article • Molecular BioSystems, January 2011, Royal Society of Chemistry

    Nicholas Shikuma

  24. Vibrio cholerae VpsT Regulates Matrix Production and Motility by Directly Sensing Cyclic di-GMP

    Article • Science, February 2010, American Association for the Advancement of Science

    Nicholas Shikuma

  25. Marine biofilms on submerged surfaces are a reservoir forEscherichia coliandVibrio cholerae

    Article • Biofouling, January 2010, Taylor & Francis

    Nicholas Shikuma

  26. Overexpression of VpsS, a Hybrid Sensor Kinase, Enhances Biofilm Formation in Vibrio cholerae

    Article • Journal of Bacteriology, June 2009, ASM Journals

    Nicholas Shikuma

  27. Identification and Characterization of OscR, a Transcriptional Regulator Involved in Osmolarity Adaptation in Vibrio cholerae

    Article • Journal of Bacteriology, March 2009, ASM Journals

    Nicholas Shikuma

  28. Temporal variation of an initial marine biofilm community and its effects on larval settlement and metamorphosis of the tubeworm Hydroides elegans

    Article • Biofilms, October 2005, Cambridge University Press

    Nicholas Shikuma