All Stories

  1. Cholesterol production and how it influences liver cancer.

    Article • Science Translational Medicine, April 2018, American Association for the Advancement of Science

    Mr Ngee Kiat (Jake) Chua

  2. A conserved degron containing an amphipathic helix regulates the cholesterol-mediated turnover of human squalene monooxygenase, a rate-limiting enzyme in cholesterol synthesis

    Article • Journal of Biological Chemistry, September 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Mr Ngee Kiat (Jake) Chua

  3. How do cells know when they have too much sterols?

    Article • Chemistry and Physics of Lipids, September 2016, Elsevier

    Mr Ngee Kiat (Jake) Chua

  4. The Regulatory Domain of Squalene Monooxygenase Contains a Re-entrant Loop and Senses Cholesterol via a Conformational Change

    Article • Journal of Biological Chemistry, October 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Mr Ngee Kiat (Jake) Chua