All Stories

  1. Leaderless RiPPs expand the repertoire of fungal secondary metabolites

    Article • Proceedings of the National Academy of Sciences, February 2026, Proceedings of the National Academy of Sciences

    Dr nancy p keller

  2. Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity

    Article • Proceedings of the National Academy of Sciences, February 2021, Proceedings of the National Academy of Sciences

    Dr nancy p keller

  3. A call to arms: Mustering secondary metabolites for success and survival of an opportunistic pathogen

    Article • PLoS Pathogens, April 2019, PLOS

    Dr nancy p keller

  4. A possible role for fumagillin in cellular damage during host infection by Aspergillus fumigatus

    Article • Virulence, September 2018, Taylor & Francis

    Scott G Filler, Dr nancy p keller, XABIER GURUCEAGA SIERRA

  5. Fungal Isocyanide Synthases and Xanthocillin Biosynthesis inAspergillus fumigatus

    Article • mBio, May 2018, ASM Journals

    Dr nancy p keller, Professor Antonis Rokas

  6. Peptide-Like Nylon-3 Polymers with Activity against Phylogenetically Diverse, Intrinsically Drug-Resistant Pathogenic Fungi

    Article • mSphere, May 2018, ASM Journals

    Dr nancy p keller

  7. Conserved Responses in a War of Small Molecules between a Plant-Pathogenic Bacterium and Fungi

    Article • mBio, May 2018, ASM Journals

    Dr nancy p keller

  8. An LaeA- and BrlA-Dependent Cellular Network Governs Tissue-Specific Secondary Metabolism in the Human PathogenAspergillus fumigatus

    Article • mSphere, March 2018, ASM Journals

    Dr nancy p keller, Professor Antonis Rokas

  9. A Cationic Polymer That Shows High Antifungal Activity against Diverse Human Pathogens

    Article • Antimicrobial Agents and Chemotherapy, July 2017, ASM Journals

    Dr nancy p keller, Christina Hull

  10. Heterogeneity Confounds Establishment of “a” Model Microbial Strain

    Article • mBio, February 2017, ASM Journals

    Dr nancy p keller

  11. Global Survey of Canonical Aspergillus flavus G Protein-Coupled Receptors

    Article • mBio, October 2014, ASM Journals

    Dr nancy p keller

  12. Spatial and temporal control of fungal natural product synthesis

    Article • Natural Product Reports, August 2014, Royal Society of Chemistry

    Dr nancy p keller

  13. Distinct Innate Immune Phagocyte Responses to Aspergillus fumigatus Conidia and Hyphae in Zebrafish Larvae

    Article • Eukaryotic Cell, May 2014, ASM Journals

    Dr nancy p keller

  14. Formation of 1-octen-3-ol from Aspergillus flavus conidia is accelerated after disruption of cells independently of Ppo oxygenases, and is not a main cause of inhibition of germination

    Article • PeerJ, May 2014, PeerJ

    Dr nancy p keller

  15. Molecular mechanisms of Aspergillus flavus secondary metabolism and development

    Article • Fungal Genetics and Biology, May 2014, Elsevier

    Dr nancy p keller

  16. A Volatile Relationship: Profiling an Inter-Kingdom Dialogue Between two Plant Pathogens, Ralstonia Solanacearum and Aspergillus Flavus

    Article • Journal of Chemical Ecology, May 2014, Springer Science + Business Media

    Dr nancy p keller, Professor Caitilyn Allen

  17. Co-ordination between BrlA regulation and secretion of the oxidoreductase FmqD directs selective accumulation of fumiquinazoline C to conidial tissues inAspergillus fumigatus

    Article • Cellular Microbiology, April 2014, Wiley

    Dr nancy p keller

  18. Genetic Regulation of Aspergillus Secondary Metabolites and Their Role in Fungal Pathogenesis

    Article • April 2014, ASM Journals

    Dr nancy p keller

  19. Aspergillus nidulans: a Model for Elucidation of Aspergillus fumigatus Secondary Metabolism

    Article • April 2014, ASM Journals

    Dr nancy p keller

  20. The bZIP Protein MeaB Mediates Virulence Attributes in Aspergillus flavus

    Article • PLOS One, September 2013, PLOS

    Dr nancy p keller

  21. VeA and MvlA repression of the cryptic orsellinic acid gene cluster inAspergillus nidulansinvolves histone 3 acetylation

    Article • Molecular Microbiology, August 2013, Wiley

    Dr nancy p keller

  22. RsmA Regulates Aspergillus fumigatus Gliotoxin Cluster Metabolites Including Cyclo(L-Phe-L-Ser), a Potential New Diagnostic Marker for Invasive Aspergillosis

    Article • PLOS One, May 2013, PLOS

    Dr nancy p keller

  23. A Novel Automethylation Reaction in the Aspergillus nidulans LaeA Protein Generates S-Methylmethionine

    Article • Journal of Biological Chemistry, March 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr nancy p keller

  24. Loss of CclA, required for histone 3 lysine 4 methylation, decreases growth but increases secondary metabolite production in Aspergillus fumigatus

    Article • PeerJ, February 2013, PeerJ

    Dr nancy p keller

  25. A Nonribosomal Peptide Synthetase-Derived Iron(III) Complex from the Pathogenic FungusAspergillus fumigatus

    Article • Journal of the American Chemical Society, February 2013, American Chemical Society (ACS)

    Dr nancy p keller

  26. Secondary Metabolism and Development Is Mediated by LlmF Control of VeA Subcellular Localization in Aspergillus nidulans

    Article • PLoS Genetics, January 2013, PLOS

    Dr nancy p keller

  27. 3 Genetics, Biosynthesis, and Regulation of Aflatoxins and other Aspergillus flavus Secondary Metabolites

    Article • January 2013, Springer Science + Business Media

    Dr nancy p keller

  28. Homologe NRPS-ähnliche Genloci vermitteln eine redundante Naturstoff-Biosynthese inAspergillus flavus

    Article • Angewandte Chemie, December 2012, Wiley

    Dr nancy p keller

  29. Homologous NRPS-like Gene Clusters Mediate Redundant Small-Molecule Biosynthesis inAspergillus flavus

    Article • Angewandte Chemie, December 2012, Wiley

    Dr nancy p keller

  30. bZIP transcription factors affecting secondary metabolism, sexual development and stress responses in Aspergillus nidulans

    Article • Microbiology, November 2012, Society for General Microbiology

    Dr nancy p keller

  31. NosA, a transcription factor important in Aspergillus fumigatus stress and developmental response, rescues the germination defect of a laeA deletion

    Article • Fungal Genetics and Biology, November 2012, Elsevier

    Dr nancy p keller

  32. Putative Calcium Channels CchA and MidA Play the Important Roles in Conidiation, Hyphal Polarity and Cell Wall Components in Aspergillus nidulans

    Article • PLOS One, October 2012, PLOS

    Dr nancy p keller

  33. Aspergillus Oxylipin Signaling and Quorum Sensing Pathways Depend on G Protein-Coupled Receptors

    Article • Toxins, September 2012, MDPI AG

    Dr nancy p keller

  34. Overexpression of theAspergillus nidulanshistone 4 acetyltransferase EsaA increases activation of secondary metabolite production

    Article • Molecular Microbiology, August 2012, Wiley

    Dr nancy p keller

  35. Genome-Based Cluster Deletion Reveals an Endocrocin Biosynthetic Pathway inAspergillus fumigatus

    Article • Applied and Environmental Microbiology, August 2012, ASM Journals

    Dr nancy p keller

  36. Faculty Opinions recommendation of Identification and characterization of a novel diterpene gene cluster in Aspergillus nidulans.

    Article • May 2012, F1000Research

    Dr nancy p keller

  37. Genome-Based Cluster Deletion Reveals an Endocrocin Biosynthetic Pathway in Aspergillus fumigatus

    Article • Applied and Environmental Microbiology, April 2012, ASM Journals

    Dr nancy p keller

  38. An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR

    Article • Molecular Microbiology, February 2012, Wiley

    Dr nancy p keller

  39. Advances in Aspergillus secondary metabolite research in the post-genomic era

    Article • Natural Product Reports, January 2012, Royal Society of Chemistry

    Dr nancy p keller

  40. Aspergillus flavus

    Article • Annual Review of Phytopathology, September 2011, Annual Reviews

    Dr nancy p keller

  41. Cryptic Aspergillus nidulans Antimicrobials

    Article • Applied and Environmental Microbiology, April 2011, ASM Journals

    Dr nancy p keller

  42. Suppressor Mutagenesis Identifies a Velvet Complex Remediator of Aspergillus nidulans Secondary Metabolism

    Article • Eukaryotic Cell, October 2010, ASM Journals

    Dr nancy p keller

  43. Telomere position effect is regulated by heterochromatin-associated proteins and NkuA in Aspergillus nidulans

    Article • Microbiology, August 2010, Society for General Microbiology

    Dr nancy p keller

  44. Fruit, flies and filamentous fungi - experimental analysis of animal-microbe competition using Drosophila melanogaster and Aspergillus mould as a model system

    Article • Oikos, May 2010, Wiley

    Dr nancy p keller

  45. Unraveling polyketide synthesis in members of the genus Aspergillus

    Article • Applied Microbiology and Biotechnology, April 2010, Springer Science + Business Media

    Dr nancy p keller

  46. Beyond aflatoxin: four distinct expression patterns and functional roles associated withAspergillus flavussecondary metabolism gene clusters

    Article • Molecular Plant Pathology, March 2010, Wiley

    Dr nancy p keller

  47. Characterization of the Aspergillus nidulans Monodictyphenone Gene Cluster

    Article • Applied and Environmental Microbiology, February 2010, ASM Journals

    Dr nancy p keller

  48. Heterochromatic marks are associated with the repression of secondary metabolism clusters in Aspergillus nidulans

    Article • Molecular Microbiology, February 2010, Wiley

    Dr nancy p keller

  49. Molecular genetic analysis of the orsellinic acid/F9775 genecluster of Aspergillus nidulans

    Article • Molecular BioSystems, January 2010, Royal Society of Chemistry

    Dr nancy p keller

  50. Aspergillus fumigatus LaeA-Mediated Phagocytosis Is Associated with a Decreased Hydrophobin Layer

    Article • Infection and Immunity, November 2009, ASM Journals

    Dr nancy p keller

  51. HdaA, a class 2 histone deacetylase of Aspergillus fumigatus, affects germination and secondary metabolite production

    Article • Fungal Genetics and Biology, October 2009, Elsevier

    Dr nancy p keller

  52. Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

    Article • Clinical Microbiology Reviews, July 2009, ASM Journals

    Dr nancy p keller

  53. Oxygenase Coordination Is Required for Morphological Transition and the Host–Fungus Interaction of Aspergillus flavus

    Article • Molecular Plant-Microbe Interactions, July 2009, Scientific Societies

    Dr nancy p keller

  54. Distinct Roles for VeA and LaeA in Development and Pathogenesis of Aspergillus flavus

    Article • Eukaryotic Cell, May 2009, ASM Journals

    Dr nancy p keller

  55. A Gene Cluster Containing Two Fungal Polyketide Synthases Encodes the Biosynthetic Pathway for a Polyketide, Asperfuranone, in Aspergillus nidulans

    Article • Journal of the American Chemical Society, February 2009, American Chemical Society (ACS)

    Dr nancy p keller

  56. Inactivation of the Lipoxygenase ZmLOX3 Increases Susceptibility of Maize to Aspergillus spp.

    Article • Molecular Plant-Microbe Interactions, February 2009, Scientific Societies

    Dr nancy p keller, Professor Ivo Feussner

  57. Real-Time and Semiquantitative RT-PCR Methods to Analyze Gene Expression Patterns During Aspergillus-Host Interactions

    Article • January 2009, Springer Science + Business Media

    Dr nancy p keller

  58. H3K9 Methylation Regulates Growth and Development in Aspergillus fumigatus

    Article • Eukaryotic Cell, October 2008, ASM Journals

    Dr nancy p keller

  59. Requirement of LaeA for secondary metabolism and sclerotial production in Aspergillus flavus

    Article • Fungal Genetics and Biology, October 2008, Elsevier

    Dr nancy p keller

  60. Morphological Transitions Governed by Density Dependence and Lipoxygenase Activity in Aspergillus flavus

    Article • Applied and Environmental Microbiology, July 2008, ASM Journals

    Dr nancy p keller

  61. Defects in Conidiophore Development and Conidium-Macrophage Interactions in a Dioxygenase Mutant of Aspergillus fumigatus

    Article • Infection and Immunity, April 2008, ASM Journals

    Dr nancy p keller

  62. A single acyl-CoA dehydrogenase is required for catabolism of isoleucine, valine and short-chain fatty acids in Aspergillus nidulans

    Article • Fungal Genetics and Biology, March 2008, Elsevier

    Dr nancy p keller

  63. Reciprocal oxylipin-mediated cross-talk in the Aspergillus-seed pathosystem

    Article • Molecular Microbiology, December 2007, Wiley

    Dr nancy p keller, Professor Ivo Feussner

  64. Aspergillus Mycoviruses Are Targets and Suppressors of RNA Silencing

    Article • Eukaryotic Cell, December 2007, ASM Journals

    Dr nancy p keller

  65. RNA Silencing Gene Truncation in the Filamentous Fungus Aspergillus nidulans

    Article • Eukaryotic Cell, December 2007, ASM Journals

    Dr nancy p keller

  66. Accurate prediction of the Aspergillus nidulans terrequinone gene cluster boundaries using the transcriptional regulator LaeA

    Article • Fungal Genetics and Biology, November 2007, Elsevier

    Dr nancy p keller

  67. Development of an Arabidopsis thaliana-based bioassay for investigating seed colonization by mycotoxigenic Aspergillus species

    Article • Plant Pathology, October 2007, Wiley

    Dr nancy p keller

  68. Identification of Dioxygenases Required for Aspergillus Development

    Article • Journal of Biological Chemistry, September 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr nancy p keller

  69. Histone Deacetylase Activity Regulates Chemical Diversity in Aspergillus

    Article • Eukaryotic Cell, July 2007, ASM Journals

    Dr nancy p keller

  70. Transcriptional Regulation of Chemical Diversity in Aspergillus fumigatus by LaeA

    Article • PLoS Pathogens, April 2007, PLOS

    Dr nancy p keller

  71. GliZ, a Transcriptional Regulator of Gliotoxin Biosynthesis, Contributes to Aspergillus fumigatus Virulence

    Article • Infection and Immunity, October 2006, ASM Journals

    Dr nancy p keller

  72. Secondary metabolic gene cluster silencing in Aspergillus nidulans

    Article • Molecular Microbiology, September 2006, Wiley

    Dr nancy p keller

  73. Oxylipins act as determinants of natural product biosynthesis and seed colonization in Aspergillus nidulans

    Article • Molecular Microbiology, February 2006, Wiley

    Dr nancy p keller

  74. LaeA, a global regulator of Aspergillus toxins

    Article • Medical Mycology, January 2006, Oxford University Press (OUP)

    Dr nancy p keller

  75. Genomic Mining for Aspergillus Natural Products

    Article • Chemistry & Biology, January 2006, Elsevier

    Dr nancy p keller

  76. Aspergillus Infection Inhibits the Expression of Peanut 13 S -HPODE-Forming Seed Lipoxygenases

    Article • Molecular Plant-Microbe Interactions, October 2005, Scientific Societies

    Dr nancy p keller, Professor Ivo Feussner

  77. Aspergillus Cyclooxygenase-Like Enzymes Are Associated with Prostaglandin Production and Virulence

    Article • Infection and Immunity, August 2005, ASM Journals

    Dr nancy p keller

  78. RNA Silencing of Mycotoxin Production in Aspergillus and Fusarium Species

    Article • Molecular Plant-Microbe Interactions, June 2005, Scientific Societies

    Dr nancy p keller, Daren Brown

  79. Endogenous Lipogenic Regulators of Spore Balance in Aspergillus nidulans

    Article • Eukaryotic Cell, December 2004, ASM Journals

    Dr nancy p keller

  80. Deletion of the Delta12-oleic acid desaturase gene of a nonaflatoxigenic Aspergillus parasiticus field isolate affects conidiation and sclerotial development

    Article • Journal of Applied Microbiology, December 2004, Wiley

    Dr nancy p keller

  81. Mitochondrial β-oxidation in Aspergillus nidulans

    Article • Molecular Microbiology, October 2004, Wiley

    Dr nancy p keller

  82. veA Is Required for Toxin and Sclerotial Production in Aspergillus parasiticus

    Article • Applied and Environmental Microbiology, August 2004, ASM Journals

    Dr nancy p keller

  83. Regulation of aflatoxin synthesis by FadA/cAMP/protein kinase A signaling in Aspergillus parasiticus

    Article • Mycopathologia, July 2004, Springer Science + Business Media

    Dr nancy p keller

  84. Two Δ9-stearic acid desaturases are required for Aspergillus nidulans growth and development

    Article • Fungal Genetics and Biology, May 2004, Elsevier

    Dr nancy p keller

  85. LaeA, a Regulator of Secondary Metabolism in Aspergillus spp

    Article • Eukaryotic Cell, April 2004, ASM Journals

    Dr nancy p keller

  86. Blockage of methylcitrate cycle inhibits polyketide production in Aspergillus nidulans

    Article • Molecular Microbiology, March 2004, Wiley

    Dr nancy p keller

  87. Chapter ten Aspergillus nidulans as a model system to study secondary metabolism

    Article • January 2004, Elsevier

    Dr nancy p keller

  88. A Circadian Oscillator in Aspergillus spp. Regulates Daily Development and Gene Expression

    Article • Eukaryotic Cell, April 2003, ASM Journals

    Dr nancy p keller, Professor Hubertus Haas

  89. Requirement of spermidine for developmental transitions in Aspergillus nidulans

    Article • Molecular Microbiology, October 2002, Wiley

    Dr nancy p keller

  90. cAMP and ras signalling independently control spore germination in the filamentous fungus Aspergillus nidulans

    Article • Molecular Microbiology, May 2002, Wiley

    Dr nancy p keller, Dr Sabine Fillinger

  91. Faculty Opinions recommendation of A single gene produces mitochondrial, cytoplasmic, and peroxisomal NADP-dependent isocitrate dehydrogenase in Aspergillus nidulans.

    Article • December 2001, F1000Research

    Dr nancy p keller

  92. Genetic Connection between Fatty Acid Metabolism and Sporulation in Aspergillus nidulans

    Article • Journal of Biological Chemistry, May 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr nancy p keller

  93. RcoA has pleiotropic effects on Aspergillus nidulans cellular development

    Article • Molecular Microbiology, March 2001, Wiley

    Dr nancy p keller

  94. Requirement of Monooxygenase-Mediated Steps for Sterigmatocystin Biosynthesis by Aspergillus nidulans

    Article • Applied and Environmental Microbiology, January 2000, ASM Journals

    Dr nancy p keller

  95. Visual Estimation of Aflatoxin Production in Peanut with Aspergillus Norsolorinic Acid Mutants 1

    Article • Terrestrial Atmospheric and Oceanic Sciences, July 1998, American Peanut Research and Education Society

    Dr nancy p keller

  96. Sequence-specific binding by Aspergillus nidulans AflR, a C6 zinc cluster protein regulating mycotoxin biosynthesis

    Article • Molecular Microbiology, June 1998, Wiley

    Dr nancy p keller

  97. pH Regulation of Sterigmatocystin and Aflatoxin Biosynthesis in Aspergillus spp.

    Article • Phytopathology, June 1997, Scientific Societies

    Dr nancy p keller

  98. Seed Lipoxygenase Products Modulate Aspergillus Mycotoxin Biosynthesis

    Article • Molecular Plant-Microbe Interactions, April 1997, Scientific Societies

    Dr nancy p keller

  99. Aspergillus nidulans stcL Encodes a Putative Cytochrome P-450 Monooxygenase Required for Bisfuran Desaturation during Aflatoxin/Sterigmatocystin Biosynthesis

    Article • Journal of Biological Chemistry, January 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr nancy p keller

  100. Aspergillus has distinct fatty acid synthases for primary and secondary metabolism

    Article • Proceedings of the National Academy of Sciences, December 1996, Proceedings of the National Academy of Sciences

    Dr nancy p keller, Daren Brown

  101. Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans.

    Article • Proceedings of the National Academy of Sciences, February 1996, Proceedings of the National Academy of Sciences

    Dr nancy p keller, Daren Brown

  102. A Visual Pattern of Mycotoxin Production in Maize Kernels by Aspergillus spp.

    Article • Phytopathology, January 1994, Scientific Societies

    Dr nancy p keller

  103. Variable electrophoretic karyotypes of members of Aspergillus Section Flavi

    Article • Current Genetics, April 1992, Springer Science + Business Media

    Dr nancy p keller

  104. Mitotic stability of transforming DNA is determined by its chromosomal configuration in the fungus Cochliobolus heterostrophus

    Article • Current Genetics, March 1991, Springer Science + Business Media

    Dr nancy p keller

  105. Developmental Predisposition of Maize to Anthracnose Stalk Rot

    Article • Plant Disease, January 1988, Scientific Societies

    Dr nancy p keller

  106. Potential Yield Reductions in Maize Associated with an Anthracnose/European Corn Borer Pest Complex in New York

    Article • Phytopathology, January 1986, Scientific Societies

    Dr nancy p keller