All Stories

  1. Design and synthesis of novel 4-hydroxycoumarin-isoxazole adducts for combating bacterial infections
  2. Biophysical and Computational Analysis of a Potent Antimalarial Compound Binding to Human Serum Albumin: Insights for Drug–Protein Interaction
  3. Integrative computational and experimental approaches for identifying potent antimalarials by targeting falcipain-2 of Plasmodium falciparum
  4. Coumarin 1,4-dihydropyridine hybrids: Synthesis, X-ray structure, cytotoxicity assay, and molecular dynamic simulation studies
  5. Biochemistry of Bacterial Biofilm: Insights into Antibiotic Resistance Mechanisms and Therapeutic Intervention
  6. Synthesis and antibacterial evaluation of quinoline–sulfonamide hybrid compounds: a promising strategy against bacterial resistance
  7. Synthesis and Structure–Activity Relationship (SAR) Studies on New 4-Aminoquinoline-Hydrazones and Isatin Hybrids as Promising Antibacterial Agents
  8. A Convenient One-Pot Synthesis of Novel Benzimidazole–Thiazinone Derivatives and Their Antimicrobial Activity
  9. Exploring the Potential of New 7‐Chloroquinoline‐benzylamine Hybrids as Antimicrobials: Synthesis, Biological Activity and MD Simulation Studies
  10. Vanillin-Isatin Hybrid-Induced MARK4 Inhibition As a Promising Therapeutic Strategy against Hepatocellular Carcinoma
  11. Evaluating Terrestrol A as an Inhibitor Against SARS‐CoV‐2and Invasive Fungal Pathogens: A Comprehensive Computational Analysis
  12. Journey of Von Hippel-Lindau (VHL) E3 ligase in PROTACs design: From VHL ligands to VHL-based degraders
  13. A Comprehensive Multispectroscopic and Computational Analysis of the Interaction between Plant-Based Antiplasmodial Compounds and Bovine Serum Albumin
  14. Synthesis of 1,2,4‐Oxadiazole‐sulfonamide Conjugates and Their Synergistic Effect with Ampicillin as Antimicrobial Agents
  15. Comparative investigation on interaction between potent antimalarials and human serum albumin using multispectroscopic and computational approaches
  16. Microbial Biofilms: Applications, Clinical Consequences, and Alternative Therapies
  17. Synergistic antimicrobial activity, MD simulation studies and crystal structure of natural alcohol motif containing novel substituted cinnamates
  18. Synthesis, spectral characterization of pyrazole derived Schiff base analogs: molecular dynamic simulation, antibacterial and DNA binding studies
  19. Design, Synthesis and Mechanistic Studies of Novel Isatin-Pyrazole Hydrazone Conjugates as Selective and Potent Bacterial MetAP Inhibitors
  20. A multi-spectroscopic and computational simulations study to delineate the interaction between antimalarial drug hydroxychloroquine and human serum albumin
  21. Prefoldin subunit 6 of Plasmodium falciparum binds merozoite surface protein‐1
  22. Mannose 2, 3, 4, 5, 6-O-pentasulfate (MPS): a partial activator of human heparin cofactor II with anticoagulation potential
  23. Structural-activity Relationship of Metallo-aminoquines as Next Generation Antimalarials
  24. Medicinal chemistry updates on quinoline- and endoperoxide-based hybrids with potent antimalarial activity
  25. Metacaspase-3 of Plasmodium falciparum: An atypical trypsin-like serine protease
  26. Design, Synthesis, and Biological Evaluation of Novel Fused Spiro-4H-Pyran Derivatives as Bacterial Biofilm Disruptor
  27. Synthesis of Novel Benzimidazolium Gemini Surfactants and Evaluation of Their Anti-Candida Activity
  28. Synthesis, Antimicrobial Evaluation and In silico Studies of Novel 2,4- disubstituted-1,3-thiazole Derivatives
  29. Antithrombotic potential of esculin 7, 3′, 4′, 5′, 6′-O-pentasulfate (EPS) for its role in thrombus reduction using rat thrombosis model
  30. The Upshot of PI3K Inhibitors as Anticancer Arsenal: A Short Review
  31. Effect of triazole-tryptophan hybrid on the conformation stability of bovine serum albumin
  32. Recent Advances in Cancer Drug Development: Targeting Induced Myeloid Cell Leukemia-1 (Mcl-1) Differentiation Protein
  33. 1,2,3-Triazole–quinazolin-4(3H)-one conjugates: evolution of ergosterol inhibitor as anticandidal agent
  34. Anti-leishmanial and cytotoxic activities of amino acid-triazole hybrids: Synthesis, biological evaluation, molecular docking and in silico physico-chemical properties
  35. Effect of quinoline based 1,2,3-triazole and its structural analogues on growth and virulence attributes of Candida albicans
  36. Synthesis, Antimicrobial Studies, and Docking Simulations of New Bis(4,5‐dihydropyrazole) Derivatives
  37. Efficient synthesis of novel N-substituted 2-carboxy-4-quinolones via lithium bis(trimethylsilyl)amide (LiHMDS)-induced in situ cyclocondensation reaction
  38. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC)
  39. Biological Activities and In Silico Physico-Chemical Properties of 1,2,3- Triazoles Derived from Natural Bioactive Alcohols
  40. Experimental and molecular docking investigation on DNA interaction ofN-substituted phthalimides: antibacterial, antioxidant and hemolytic activities
  41. Ruthenium Complexes: An Emerging Ground to the Development of Metallopharmaceuticals for Cancer Therapy
  42. ChemInform Abstract: A Structure Guided Drug-Discovery Approach Towards Identification of Plasmodium Inhibitors
  43. A structure guided drug-discovery approach towards identification of Plasmodium inhibitors
  44. Effect of novel triazole–amino acid hybrids on growth and virulence of Candida species: in vitro and in vivo studies
  45. Evaluation of DNA Binding, Radicals Scavenging and Antimicrobial Studies of Newly Synthesized N-Substituted Naphthalimides: Spectroscopic and Molecular Docking Investigations
  46. Monocyclic β -lactam and unexpected oxazinone formation: synthesis, crystal structure, docking studies and antibacterial evaluation
  47. Synthesis, QSAR and anticandidal evaluation of 1,2,3-triazoles derived from naturally bioactive scaffolds
  48. Diketo acids and their amino acid/dipeptidic analogues as promising scaffolds for the development of bacterial methionine aminopeptidase inhibitors
  49. Polysulfated Trehalose as a Novel Anticoagulant Agent with Dual Mode of Action
  50. Elucidating the specificity of non-heparin-based conformational activators of antithrombin for factor Xa inhibition
  51. Synthesis of N-2-aryl-substituted-1,2,3-triazole Derivatives as Novel Inhibitors of Entamoeba histolytica
  52. Limitations of conventional anticoagulant therapy and the promises of non-heparin based conformational activators of antithrombin
  53. ChemInform Abstract: Synthesis, Spectral Studies and Antiamoebic Activity of New 1-N-Substituted Thiocarbamoyl-3-phenyl-2-pyrazolines.
  54. Synthesis, spectral studies and antiamoebic activity of new 1-N-substituted thiocarbamoyl-3-phenyl-2-pyrazolines
  55. Synthesis and antiamoebic activity of metronidazole thiosemicarbazone analogues
  56. Novel Pd(II) complexes of 1-N-substituted 3-phenyl-2-pyrazoline derivatives and evaluation of antiamoebic activity
  57. Synthesis, characterization and antiamoebic activity of new indole-3-carboxaldehyde thiosemicarbazones and their Pd(II) complexes
  58. Syntheses, characterization and in vitro antiamoebic activity of new Pd(II) complexes with 1-N-substituted thiocarbamoyl-3,5-diphenyl-2-pyrazoline derivatives
  59. Synthesis, Characterization and Antiamoebic Activity of 1-(Thiazolo[4,5-b]quinoxaline-2-yl)-3-phenyl-2-pyrazoline Derivatives.
  60. Synthesis, characterization and antiamoebic activity of 1-(thiazolo[4,5-b]quinoxaline-2-yl)-3-phenyl-2-pyrazoline derivatives
  61. Dioxovanadium(V) and μ-oxo bis[oxovanadium(V)] complexes containing thiosemicarbazone based ONS donor set and their antiamoebic activity
  62. 1-N-Substituted Thiocarbamoyl-3-phenyl-2-pyrazolines: Synthesis and in vitro Antiamoebic Activities.
  63. Synthesis, characterisation, reactivity and in vitro antiamoebic activity of hydrazone based oxovanadium(iv), oxovanadium(v) and µ-bis(oxo)bis{oxovanadium(v)} complexes
  64. Synthesis and Anti-Amoebic Activity of Gold(I), Ruthenium(II), and Copper(II) Complexes of Metronidazole
  65. Synthesis and antiamoebic activity of new oxime ether derivatives containing 2-acetylpyridine/2-acetylfuran
  66. Synthesis and antiamoebic activities of 1-N-substituted cyclised pyrazoline analogues of thiosemicarbazones