All Stories

  1. Synthesis and Bioactivity of Novel 1,2,4‐Oxadiazole–Sulfonamide Hybrids as Potent Antibacterial Agents Against Klebsiella pneumoniae
  2. Synthesis, characterization, antifungal, Ct-DNA binding, catalytic activity, DFT and molecular docking studies of transition metal complexes derived from quinoline based ligand ​
  3. Design and synthesis of novel 4-hydroxycoumarin-isoxazole adducts for combating bacterial infections
  4. Biophysical and Computational Analysis of a Potent Antimalarial Compound Binding to Human Serum Albumin: Insights for Drug–Protein Interaction
  5. Integrative computational and experimental approaches for identifying potent antimalarials by targeting falcipain-2 of Plasmodium falciparum
  6. Coumarin 1,4-dihydropyridine hybrids: Synthesis, X-ray structure, cytotoxicity assay, and molecular dynamic simulation studies
  7. Biochemistry of Bacterial Biofilm: Insights into Antibiotic Resistance Mechanisms and Therapeutic Intervention
  8. Synthesis and antibacterial evaluation of quinoline–sulfonamide hybrid compounds: a promising strategy against bacterial resistance
  9. Synthesis and Structure–Activity Relationship (SAR) Studies on New 4-Aminoquinoline-Hydrazones and Isatin Hybrids as Promising Antibacterial Agents
  10. A Convenient One-Pot Synthesis of Novel Benzimidazole–Thiazinone Derivatives and Their Antimicrobial Activity
  11. Exploring the Potential of New 7‐Chloroquinoline‐benzylamine Hybrids as Antimicrobials: Synthesis, Biological Activity and MD Simulation Studies
  12. Vanillin-Isatin Hybrid-Induced MARK4 Inhibition As a Promising Therapeutic Strategy against Hepatocellular Carcinoma
  13. Evaluating Terrestrol A as an Inhibitor Against SARS‐CoV‐2and Invasive Fungal Pathogens: A Comprehensive Computational Analysis
  14. Journey of Von Hippel-Lindau (VHL) E3 ligase in PROTACs design: From VHL ligands to VHL-based degraders
  15. A Comprehensive Multispectroscopic and Computational Analysis of the Interaction between Plant-Based Antiplasmodial Compounds and Bovine Serum Albumin
  16. Synthesis of 1,2,4‐Oxadiazole‐sulfonamide Conjugates and Their Synergistic Effect with Ampicillin as Antimicrobial Agents
  17. Comparative investigation on interaction between potent antimalarials and human serum albumin using multispectroscopic and computational approaches
  18. Microbial Biofilms: Applications, Clinical Consequences, and Alternative Therapies
  19. Synergistic antimicrobial activity, MD simulation studies and crystal structure of natural alcohol motif containing novel substituted cinnamates
  20. Synthesis, spectral characterization of pyrazole derived Schiff base analogs: molecular dynamic simulation, antibacterial and DNA binding studies
  21. Design, Synthesis and Mechanistic Studies of Novel Isatin-Pyrazole Hydrazone Conjugates as Selective and Potent Bacterial MetAP Inhibitors
  22. A multi-spectroscopic and computational simulations study to delineate the interaction between antimalarial drug hydroxychloroquine and human serum albumin
  23. Prefoldin subunit 6 of Plasmodium falciparum binds merozoite surface protein‐1
  24. Mannose 2, 3, 4, 5, 6-O-pentasulfate (MPS): a partial activator of human heparin cofactor II with anticoagulation potential
  25. Structural-activity Relationship of Metallo-aminoquines as Next Generation Antimalarials
  26. Medicinal chemistry updates on quinoline- and endoperoxide-based hybrids with potent antimalarial activity
  27. Metacaspase-3 of Plasmodium falciparum: An atypical trypsin-like serine protease
  28. Design, Synthesis, and Biological Evaluation of Novel Fused Spiro-4H-Pyran Derivatives as Bacterial Biofilm Disruptor
  29. Synthesis of Novel Benzimidazolium Gemini Surfactants and Evaluation of Their Anti-Candida Activity
  30. Synthesis, Antimicrobial Evaluation and In silico Studies of Novel 2,4- disubstituted-1,3-thiazole Derivatives
  31. Antithrombotic potential of esculin 7, 3′, 4′, 5′, 6′-O-pentasulfate (EPS) for its role in thrombus reduction using rat thrombosis model
  32. The Upshot of PI3K Inhibitors as Anticancer Arsenal: A Short Review
  33. Effect of triazole-tryptophan hybrid on the conformation stability of bovine serum albumin
  34. Recent Advances in Cancer Drug Development: Targeting Induced Myeloid Cell Leukemia-1 (Mcl-1) Differentiation Protein
  35. 1,2,3-Triazole–quinazolin-4(3H)-one conjugates: evolution of ergosterol inhibitor as anticandidal agent
  36. Anti-leishmanial and cytotoxic activities of amino acid-triazole hybrids: Synthesis, biological evaluation, molecular docking and in silico physico-chemical properties
  37. Effect of quinoline based 1,2,3-triazole and its structural analogues on growth and virulence attributes of Candida albicans
  38. Synthesis, Antimicrobial Studies, and Docking Simulations of New Bis(4,5‐dihydropyrazole) Derivatives
  39. Efficient synthesis of novel N-substituted 2-carboxy-4-quinolones via lithium bis(trimethylsilyl)amide (LiHMDS)-induced in situ cyclocondensation reaction
  40. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC)
  41. Biological Activities and In Silico Physico-Chemical Properties of 1,2,3- Triazoles Derived from Natural Bioactive Alcohols
  42. Experimental and molecular docking investigation on DNA interaction ofN-substituted phthalimides: antibacterial, antioxidant and hemolytic activities
  43. Ruthenium Complexes: An Emerging Ground to the Development of Metallopharmaceuticals for Cancer Therapy
  44. ChemInform Abstract: A Structure Guided Drug-Discovery Approach Towards Identification of Plasmodium Inhibitors
  45. A structure guided drug-discovery approach towards identification of Plasmodium inhibitors
  46. Effect of novel triazole–amino acid hybrids on growth and virulence of Candida species: in vitro and in vivo studies
  47. Evaluation of DNA Binding, Radicals Scavenging and Antimicrobial Studies of Newly Synthesized N-Substituted Naphthalimides: Spectroscopic and Molecular Docking Investigations
  48. Monocyclic β -lactam and unexpected oxazinone formation: synthesis, crystal structure, docking studies and antibacterial evaluation
  49. Synthesis, QSAR and anticandidal evaluation of 1,2,3-triazoles derived from naturally bioactive scaffolds
  50. Diketo acids and their amino acid/dipeptidic analogues as promising scaffolds for the development of bacterial methionine aminopeptidase inhibitors
  51. Polysulfated Trehalose as a Novel Anticoagulant Agent with Dual Mode of Action
  52. Elucidating the specificity of non-heparin-based conformational activators of antithrombin for factor Xa inhibition
  53. Synthesis of N-2-aryl-substituted-1,2,3-triazole Derivatives as Novel Inhibitors of Entamoeba histolytica
  54. Limitations of conventional anticoagulant therapy and the promises of non-heparin based conformational activators of antithrombin
  55. ChemInform Abstract: Synthesis, Spectral Studies and Antiamoebic Activity of New 1-N-Substituted Thiocarbamoyl-3-phenyl-2-pyrazolines.
  56. Synthesis, spectral studies and antiamoebic activity of new 1-N-substituted thiocarbamoyl-3-phenyl-2-pyrazolines
  57. Synthesis and antiamoebic activity of metronidazole thiosemicarbazone analogues
  58. Novel Pd(II) complexes of 1-N-substituted 3-phenyl-2-pyrazoline derivatives and evaluation of antiamoebic activity
  59. Synthesis, characterization and antiamoebic activity of new indole-3-carboxaldehyde thiosemicarbazones and their Pd(II) complexes
  60. Syntheses, characterization and in vitro antiamoebic activity of new Pd(II) complexes with 1-N-substituted thiocarbamoyl-3,5-diphenyl-2-pyrazoline derivatives
  61. Synthesis, Characterization and Antiamoebic Activity of 1-(Thiazolo[4,5-b]quinoxaline-2-yl)-3-phenyl-2-pyrazoline Derivatives.
  62. Synthesis, characterization and antiamoebic activity of 1-(thiazolo[4,5-b]quinoxaline-2-yl)-3-phenyl-2-pyrazoline derivatives
  63. Dioxovanadium(V) and μ-oxo bis[oxovanadium(V)] complexes containing thiosemicarbazone based ONS donor set and their antiamoebic activity
  64. 1-N-Substituted Thiocarbamoyl-3-phenyl-2-pyrazolines: Synthesis and in vitro Antiamoebic Activities.
  65. Synthesis, characterisation, reactivity and in vitro antiamoebic activity of hydrazone based oxovanadium(iv), oxovanadium(v) and µ-bis(oxo)bis{oxovanadium(v)} complexes
  66. Synthesis and Anti-Amoebic Activity of Gold(I), Ruthenium(II), and Copper(II) Complexes of Metronidazole
  67. Synthesis and antiamoebic activity of new oxime ether derivatives containing 2-acetylpyridine/2-acetylfuran
  68. Synthesis and antiamoebic activities of 1-N-substituted cyclised pyrazoline analogues of thiosemicarbazones