All Stories

  1. Thymol nanoparticles ameliorate oxaliplatin-induced cognitive impairment via modulation of Nrf2/HO-1, endoplasmic reticulum stress, and NLRP3 inflammasome signaling in rats

    Article • Biomedicine & Pharmacotherapy, July 2026, Elsevier

    Dr Mina Y. George

  2. Canagliflozin attenuates Parkinson’s disease and is associated with modulation of gut-inflammasome–brain axis in rats

    Article • Inflammopharmacology, June 2026, Springer Science + Business Media

    Dr Mina Y. George

  3. Troxerutin attenuates paclitaxel-induced cardiotoxicity through modulation of ferroptosis and GRP78/ATF6/CHOP signaling in rats

    Article • European Journal of Pharmacology, June 2026, Elsevier

    Dr Mina Y. George

  4. Neurodegeneration at the crossroads: the gut-brain axis and blood-brain barrier in Parkinson’s disease — a review

    Article • Frontiers in Pharmacology, May 2026, Frontiers

    Dr Mina Y. George

  5. Chemical composition of Callistemon subulatus essential oils and the protective effects against cyclophosphamide-induced lung toxicity: GC/MS metabolic profiling with in vivo and in silico experimental studies

    Article • Frontiers in Pharmacology, April 2026, Frontiers

    Dr Mina Y. George

  6. Breaking Barriers: Intranasal Microemulsions for the Efficient Nose-to-brain Delivery of Glycyrrhetinic Acid

    Article • AAPS PharmSciTech, February 2026, Springer Science + Business Media

    Dr Mina Y. George

  7. Expanding Therapeutic Horizons: A Review of Tadalafil’s Off-Label Applications and Pharmacological Profile

    Article • Archives of Pharmaceutical Sciences Ain Shams University, January 2026, Egypts Presidential Specialized Council for Education and Scientific Research

    Dr Mina Y. George

  8. From Glucose Transport to Microbial Modulation: The Impact of Sodium Glucose Co-Transporter-2 Inhibitors on the Gut Microbiota

    Article • Medical Sciences, January 2026, MDPI AG

    Dr Mina Y. George

  9. Protective effect of Rosmarinus officinalis and its nanoparticles against chemobrain and neuroinflammation in rats: involvement of Wnt/β-catenin signaling and apoptotic machineries

    Article • Food & Function, January 2026, Royal Society of Chemistry

    Dr Mina Y. George

  10. Phosphodiesterase Inhibitors

    Article • December 2025, Taylor & Francis

    Dr Mina Y. George

  11. Iron Overload and Excitotoxicity: Connecting Ferroptosis with Epileptic Seizures

    Article • Archives of Pharmaceutical Sciences Ain Shams University, November 2025, Egypts Presidential Specialized Council for Education and Scientific Research

    Dr Mina Y. George

  12. The Gut Microbiome Role in Multiple Myeloma: Emerging Insights and Therapeutic Opportunities

    Article • Hematology Reports, October 2025, MDPI AG

    Dr Mina Y. George

  13. Paclitaxel-induced Cardiotoxicity: Mechanisms, Molecular Insights, and Clinical Implications

    Article • Archives of Pharmaceutical Sciences Ain Shams University, October 2025, Egypts Presidential Specialized Council for Education and Scientific Research

    Dr Mina Y. George

  14. Acai-berry ameliorates Cisplatin-induced nephrotoxicity in rats; insights on oxidative stress and apoptotic machineries

    Article • Archives of Pharmaceutical Sciences Ain Shams University, October 2025, Egypts Presidential Specialized Council for Education and Scientific Research

    Dr Mina Y. George

  15. Unveiling Psychosis; Clinical Presentation, Therapeutic Modalities, and Key Signaling Pathways.

    Article • Archives of Pharmaceutical Sciences Ain Shams University, October 2025, Egypts Presidential Specialized Council for Education and Scientific Research

    Dr Mina Y. George

  16. Familial Mediterranean Fever: Unraveling its Causes, Clinical presentation, and Innovative Treatment Strategies

    Article • Archives of Pharmaceutical Sciences Ain Shams University, October 2025, Egypts Presidential Specialized Council for Education and Scientific Research

    Dr Mina Y. George

  17. The cortisol axis and psychiatric disorders: an updated review

    Article • Pharmacological Reports, September 2025, Springer Science + Business Media

    Dr Mina Y. George

  18. Tectona grandis metabolites alleviate oxaliplatin-induced chemofog in rats: Modulation of the NLRP3 inflammasome axis

    Article • Journal of Ethnopharmacology, September 2025, Elsevier

    Dr Mina Y. George

  19. Paclitaxel-induced adverse effects: insights into multi-organ toxicities and molecular mechanisms

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, August 2025, Springer Science + Business Media

    Dr Mina Y. George

  20. Verification of the anticholinesterase activity of Tectona grandis and Rosemarinus officinalis in vitro and in silico

    Article • Journal of Advanced Research, August 2025, Elsevier

    Dr Mina Y. George

  21. The Role of MiRNAs in Moyamoya Disease: Vascular Remodeling and Stroke Risk

    Article • The Journal of Gene Medicine, July 2025, Wiley

    Dr Mina Y. George

  22. Intranasal delivery of blackberry-loaded Chitosan nanoparticles for antipsychotic potential in Ketamine-induced schizophrenia in rats

    Article • Scientific Reports, May 2025, Springer Science + Business Media

    Dr Mina Y. George

  23. The antifibrotic effect of Vildagliptin and Diaminodiphenyl Sulfone in murine schistosomiasis mansoni

    Article • Scientific Reports, March 2025, Springer Science + Business Media

    Dr Mina Y. George

  24. Lycopene mitigates paclitaxel-induced cognitive impairment in mice; Insights into Nrf2/HO-1, NF-κB/NLRP3, and GRP-78/ATF-6 axes

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, March 2025, Elsevier

    Dr Mina Y. George

  25. Neuromodulatory effect of troxerutin against doxorubicin and cyclophosphamide-induced cognitive impairment in rats: Potential crosstalk between gut–brain and NLRP3 inflammasome axes

    Article • International Immunopharmacology, March 2025, Elsevier

    Dr Mina Y. George

  26. Silymarin nanoparticles counteract cognitive impairment induced by doxorubicin and cyclophosphamide in rats; Insights into mitochondrial dysfunction and Nrf-2/HO-1 axis

    Article • European Journal of Pharmacology, February 2025, Elsevier

    Dr Mina Y. George

  27. Canagliflozin differentially modulates carfilzomib-induced endoplasmic reticulum stress in multiple myeloma and endothelial cells

    Article • Archives of Toxicology, December 2024, Springer Science + Business Media

    Dr Mina Y. George

  28. Mechanisms of ferroptotic and non-ferroptotic organ toxicity of chemotherapy: protective and therapeutic effects of ginger, 6-gingerol and zingerone in preclinical studies

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, December 2024, Springer Science + Business Media

    Dr Mina Y. George

  29. Recent pharmacological insights on abating toxic protein species burden in neurological disorders: Emphasis on 26S proteasome activation

    Article • Life Sciences, December 2024, Elsevier

    Dr Mina Y. George

  30. Harnessing Melatonergic Agonists and Antagonists: A Dual Approach to Alleviating Depression and Depression-associated Insomnia

    Article • Archives of Pharmaceutical Sciences Ain Shams University, December 2024, Egypts Presidential Specialized Council for Education and Scientific Research

    Dr Mina Y. George

  31. Trace elements and metal nanoparticles: mechanistic approaches to mitigating chemotherapy-induced toxicity—a review of literature evidence

    Article • BioMetals, September 2024, Springer Science + Business Media

    Dr. Cletus Anes UKWUBILE, Dr Mina Y. George

  32. Abstract Mo004: The Protective Effects of Empagliflozin in Carfilzomib-induced Cardiotoxicity in Mice: Unveiling the Crosstalk between Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, and Autophagy Axes.

    Article • Circulation Research, August 2024, Wolters Kluwer Health

    Dr Mina Y. George

  33. Mechanisms and Protective Strategies in Cognitive Impairment Induced by Combination of Doxorubicin and Cyclophosphamide

    Article • Archives of Pharmaceutical Sciences Ain Shams University, June 2024, Egypts Presidential Specialized Council for Education and Scientific Research

    Dr Mina Y. George

  34. Empagliflozin Alleviates Carfilzomib-Induced Cardiotoxicity in Mice by Modulating Oxidative Stress, Inflammatory Response, Endoplasmic Reticulum Stress, and Autophagy

    Article • Antioxidants, May 2024, MDPI AG

    Dr Mina Y. George

  35. The Cardioprotective and Anticancer Effects of SGLT2 Inhibitors

    Article • JACC CardioOncology, April 2024, Elsevier

    Dr Mina Y. George

  36. Clotrimazole ameliorates chronic mild stress-induced depressive-like behavior in rats; crosstalk between the HPA, NLRP3 inflammasome, and Wnt/β-catenin pathways

    Article • International Immunopharmacology, January 2024, Elsevier

    Dr Mina Y. George

  37. Empagliflozin repurposing in Parkinson’s disease; modulation of oxidative stress, neuroinflammation, AMPK/SIRT-1/PGC-1α, and wnt/β-catenin pathways

    Article • Inflammopharmacology, December 2023, Springer Science + Business Media

    Dr Mina Y. George

  38. Lactoferrin ameliorates carfilzomib-induced renal and pulmonary deficits: Insights to the inflammasome NLRP3/NF-κB and PI3K/Akt/GSK-3β/MAPK axes

    Article • Life Sciences, December 2023, Elsevier

    Dr Mina Y. George

  39. In vivo hepatoprotective and nephroprotective effects ofStenocarpus sinuatusleaf extract against ifosfamide‐induced toxicity in rats

    Article • Archiv der Pharmazie, November 2023, Wiley

    Dr Mina Y. George

  40. Phytochemical profiling and neuroprotective activity of Callistemon subulatus leaves against cyclophosphamide-induced chemobrain

    Article • Biomedicine & Pharmacotherapy, November 2023, Elsevier

    Dr Mina Y. George

  41. Nose-to-brain delivery of 18β-Glycyrrhetinic acid using optimized lipid nanocapsules: A novel alternative treatment for Alzheimer’s disease

    Article • International Journal of Pharmaceutics, October 2023, Elsevier

    Dr Mina Y. George

  42. Neuromodulatory effect of vardenafil on aluminium chloride/d-galactose induced Alzheimer’s disease in rats: emphasis on amyloid-beta, p-tau, PI3K/Akt/p53 pathway, endoplasmic reticulum stress, and cellular senescence

    Article • Inflammopharmacology, July 2023, Springer Science + Business Media

    Dr Mina Y. George

  43. Roflumilast escalates α-synuclein aggregate degradation in rotenone-induced Parkinson's disease in rats: Modulation of the ubiquitin-proteasome system and endoplasmic reticulum stress

    Article • Chemico-Biological Interactions, July 2023, Elsevier

    Dr Mina Y. George

  44. Nose to brain delivery of naringin-loaded chitosan nanoparticles for potential use in oxaliplatin-induced chemobrain in rats: impact on oxidative stress, cGAS/STING and HMGB1/RAGE/TLR2/MYD88 inflammatory axes

    Article • Expert Opinion on Drug Delivery, June 2023, Taylor & Francis

    Dr John Youshia, Dr Mina Y. George

  45. L-carnitine Modulates Cognitive Impairment Induced by Doxorubicin and Cyclophosphamide in Rats; Insights to Oxidative Stress, Inflammation, Synaptic Plasticity, Liver/brain, and Kidney/brain Axes

    Article • Journal of Neuroimmune Pharmacology, May 2023, Springer Science + Business Media

    Dr Mina Y. George

  46. Chemical characterization of the polyphenolic rich fraction of Thunbergia erecta and its therapeutic potential against doxorubicin and cyclophosphamide-induced cognitive impairment in rats

    Article • Journal of Ethnopharmacology, May 2023, Elsevier

    Dr Mina Y. George

  47. Design and evaluation of chrysin-loaded nanoemulsion against lithium/pilocarpine-induced status epilepticus in rats; emphasis on formulation, neuronal excitotoxicity, oxidative stress, microglia polarization, and AMPK/SIRT-1/PGC-1α pathway

    Article • Expert Opinion on Drug Delivery, December 2022, Taylor & Francis

    Dr Mina Y. George

  48. Insights into the neuroprotective effects of Salvia officinalis L. and Salvia microphylla Kunth in the memory impairment rat model

    Article • Food & Function, January 2022, Royal Society of Chemistry

    Dr Mina Y. George

  49. Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress and TLR4/NF-kB/NLRP3 pathways

    Article • Neuropharmacology, October 2021, Elsevier

    Dr Mina Y. George

  50. Design and synthesis of novel 4-fluorobenzamide-based derivatives as promising anti-inflammatory and analgesic agents with an enhanced gastric tolerability and COX-inhibitory activity

    Article • Bioorganic Chemistry, October 2021, Elsevier

    Dr Mina Y. George

  51. Naringin treatment improved main clozapine‐induced adverse effects in rats; emphasis on weight gain, metabolic abnormalities, and agranulocytosis

    Article • Drug Development Research, February 2021, Wiley

    Dr Mina Y. George

  52. Potential therapeutic antipsychotic effects of Naringin against ketamine-induced deficits in rats: Involvement of Akt/GSK-3β and Wnt/β-catenin signaling pathways

    Article • Life Sciences, May 2020, Elsevier

    Dr Mina Y. George

  53. In vivo cellular and molecular gastroprotective mechanisms of chrysin; Emphasis on oxidative stress, inflammation and angiogenesis

    Article • European Journal of Pharmacology, January 2018, Elsevier

    Dr Mina Y. George