All Stories

  1. A Novel Early Memory-Enriched Allogeneic NKG2D CAR-T Cell Therapy Based on CRISPR/Cas9 Technology for Solid Tumors

    Article • Cancers, September 2025, MDPI AG

    Miguel de la fuente

  2. Decreased expression of insulin-degrading enzyme increases gluconeogenesis and glucose production in cultured hepatocytes administered with glucagon

    Article • Scientific Reports, May 2025, Springer Science + Business Media

    Miguel de la fuente

  3. Identification of a novel transcript of mouse Sdha

    Article • BMC Research Notes, February 2025, Springer Science + Business Media

    Miguel de la fuente

  4. LYP regulates SLP76 and other adaptor proteins in T cells

    Article • Biological Research, September 2024, Springer Science + Business Media

    Miguel de la fuente

  5. Succinate Dehydrogenase and Human Disease: Novel Insights into a Well-Known Enzyme

    Article • Biomedicines, September 2024, MDPI AG

    Miguel de la fuente

  6. Clinical exome analysis and targeted gene repair of the c.1354dupT variant in iPSC lines from patients with PROM1-related retinopathies exhibiting diverse phenotypes

    Article • Stem Cell Research & Therapy, July 2024, Springer Science + Business Media

    Mrs Rosa M Coco Martin, Miguel de la fuente

  7. The mitochondrial signature of cultured endothelial cells in sepsis: Identifying potential targets for treatment

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, February 2024, Elsevier

    Miguel de la fuente

  8. Immunohistochemical characterization of pluripotency of an iPSC line derived from a patient with cone‐rod dystrophy related to a mutation in the PROM1 gene

    Article • Acta Ophthalmologica, January 2024, Wiley

    Miguel de la fuente

  9. Molecular characterization of an iPSC line derived from a patient with cone‐rod dystrophy related to a mutation in the PROM1 gene

    Article • Acta Ophthalmologica, January 2024, Wiley

    Miguel de la fuente

  10. Development of a novel in vitro model to study the modulatory role of the respiratory complex I in macrophage effector functions

    Article • PLOS One, September 2023, PLOS

    Miguel de la fuente

  11. The mitochondrial succinate dehydrogenase complex controls the STAT3-IL-10 pathway in inflammatory macrophages

    Article • iScience, August 2023, Elsevier

    Miguel de la fuente

  12. Characterization of endogenous Kv1.3 channel isoforms in T cells

    Article • Journal of Cellular Physiology, February 2023, Wiley

    Miguel de la fuente

  13. Gene editing strategy for development of an inherited retinal dystrophy model based on iPSC‐derived photoreceptors with mutation in the PROM1 gene

    Article • Acta Ophthalmologica, December 2022, Wiley

    Mrs Rosa M Coco Martin, Miguel de la fuente

  14. Characterization of endogenous Kv1.3 channel isoforms in T cells

    Article • Biophysical Journal, February 2022, Elsevier

    Miguel de la fuente

  15. CRISPR/CasRx Proof-of-Concept for RNA Degradation: A Future Tool against RNA Viruses?

    Article • Pharmaceuticals, December 2021, MDPI AG

    Miguel de la fuente

  16. Cell Therapy for Colorectal Cancer: The Promise of Chimeric Antigen Receptor (CAR)-T Cells

    Article • International Journal of Molecular Sciences, October 2021, MDPI AG

    Miguel de la fuente

  17. Systematic Analysis of FASTK Gene Family Alterations in Cancer

    Article • International Journal of Molecular Sciences, October 2021, MDPI AG

    Miguel de la fuente

  18. Novel fluorescent-based reporter cell line engineered for monitoring homologous recombination events

    Article • PLOS One, April 2021, PLOS

    Miguel de la fuente

  19. Voltage‐dependent conformational changes of Kv1.3 channels activate cell proliferation

    Article • Journal of Cellular Physiology, November 2020, Wiley

    Miguel de la fuente

  20. Myocardin-Dependent Kv1.5 Channel Expression Prevents Phenotypic Modulation of Human Vessels in Organ Culture

    Article • Arteriosclerosis Thrombosis and Vascular Biology, December 2019, Wolters Kluwer Health

    Miguel de la fuente

  21. Pancreatic β-cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and β-cell functional immaturity

    Article • AJP Endocrinology and Metabolism, November 2019, American Physiological Society

    Miguel de la fuente

  22. Mast cells regulate CD4+ T-cell differentiation in the absence of antigen presentation

    Article • Journal of Allergy and Clinical Immunology, December 2018, Elsevier

    Miguel de la fuente

  23. The Mitochondrial Isoform of FASTK Modulates Nonopsonic Phagocytosis of Bacteria by Macrophages via Regulation of Respiratory Complex I

    Article • The Journal of Immunology, November 2018, Oxford University Press (OUP)

    Miguel de la fuente

  24. Impact of Metabolism on Immune Responses

    Article • Journal of Immunology Research, July 2018, Hindawi Publishing Corporation

    Miguel de la fuente

  25. Transcription factor induced conversion of human fibroblasts towards the hair cell lineage

    Article • PLOS One, July 2018, PLOS

    Miguel de la fuente

  26. Mast Cells Regulate CD4+ T Cell Differentiation in Absence of Antigen Presentation

    Article • Transplantation, July 2018, Wolters Kluwer Health

    Miguel de la fuente

  27. Voltage-Dependent Conformational Changes of KV1.3 Potassium Channels are an Essential Element for KV1.3-induced cell proliferation

    Article • Biophysical Journal, February 2018, Elsevier

    Miguel de la fuente

  28. Mitochondrial Complex I Dysfunction and Peripheral Chemoreflex Sensitivity in a FASTK-Deficient Mice Model

    Article • January 2018, Springer Science + Business Media

    Miguel de la fuente

  29. The FASTK family of proteins: emerging regulators of mitochondrial RNA biology

    Article • Nucleic Acids Research, September 2017, Oxford University Press (OUP)

    Miguel de la fuente

  30. Role of FAST Kinase Domains 3 (FASTKD3) in Post-transcriptional Regulation of Mitochondrial Gene Expression

    Article • Journal of Biological Chemistry, December 2016, Elsevier

    Miguel de la fuente

  31. NAD+ regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4+ CD25+ Foxp3+ T cells independent

    Article • Scientific Reports, March 2016, Springer Science + Business Media

    Miguel de la fuente

  32. Molecular Determinants of Kv1.3 Potassium Channels-induced Proliferation

    Article • Journal of Biological Chemistry, February 2016, Elsevier

    Miguel de la fuente

  33. Deletion of FAST (Fas-activated serine/threonine phosphoprotein) ameliorates immune complex arthritis in mice

    Article • Modern Rheumatology, November 2015, Oxford University Press (OUP)

    Miguel de la fuente

  34. NAD+ protects against EAE by regulating CD4+ T-cell differentiation

    Article • Nature Communications, October 2014, Springer Science + Business Media

    Miguel de la fuente

  35. Proline‐serine‐threonine phosphatase interacting protein 1 inhibition of T‐cell receptor signaling depends on its SH3 domain

    Article • European Journal of Biochemistry, August 2014, Wiley

    Mariano Sanchez Crespo, Miguel de la fuente

  36. B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice

    Article • Blood, March 2012, American Society of Hematology

    Miguel de la fuente

  37. Reduced thymic output, cell cycle abnormalities, and increased apoptosis of T lymphocytes in patients with cartilage-hair hypoplasia

    Article • Journal of Allergy and Clinical Immunology, July 2011, Elsevier

    Miguel de la fuente

  38. Fas-Activated Serine/Threonine Phosphoprotein Promotes Immune-Mediated Pulmonary Inflammation

    Article • The Journal of Immunology, May 2010, Oxford University Press (OUP)

    Miguel de la fuente

  39. WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function

    Article • Blood, November 2008, American Society of Hematology

    Miguel de la fuente

  40. F.65. The Wiskott-Aldrich Syndrome Protein is Essential for Development and Correct Function of the Marginal Zone

    Article • Clinical Immunology, January 2008, Elsevier

    Miguel de la fuente

  41. Transcellular Diapedesis Is Initiated by Invasive Podosomes

    Article • Immunity, June 2007, Elsevier

    Miguel de la fuente

  42. WIP is a chaperone for Wiskott–Aldrich syndrome protein (WASP)

    Article • Proceedings of the National Academy of Sciences, January 2007, Proceedings of the National Academy of Sciences

    Miguel de la fuente

  43. 3BP2 Deficiency Impairs the Response of B Cells, but Not T Cells, to Antigen Receptor Ligation

    Article • Molecular and Cellular Biology, July 2006, ASM Journals

    Miguel de la fuente

  44. Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome

    Article • Journal of Allergy and Clinical Immunology, December 2005, Elsevier

    Miguel de la fuente

  45. WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1α

    Article • International Immunology, September 2005, Oxford University Press (OUP)

    Miguel de la fuente

  46. CD229 (Ly9) Lymphocyte Cell Surface Receptor Interacts Homophilically through Its N-Terminal Domain and Relocalizes to the Immunological Synapse

    Article • The Journal of Immunology, June 2005, Oxford University Press (OUP)

    Miguel de la fuente

  47. WIP Regulates Signaling via the High Affinity Receptor for Immunoglobulin E in Mast Cells

    Article • Journal of Experimental Medicine, February 2004, Rockefeller University Press

    Miguel de la fuente

  48. Mechanism of Recruitment of WASP to the Immunological Synapse and of Its Activation Following TCR Ligation

    Article • Molecular Cell, December 2002, Elsevier

    Miguel de la fuente

  49. WIP Deficiency Reveals a Differential Role for WIP and the Actin Cytoskeleton in T and B Cell Activation

    Article • Immunity, February 2002, Elsevier

    Miguel de la fuente

  50. Differential role of SLP-76 domains in T cell development and function

    Article • Proceedings of the National Academy of Sciences, January 2002, Proceedings of the National Academy of Sciences

    Miguel de la fuente

  51. CD84 Functions as a Homophilic Adhesion Molecule and Enhances IFN-γ Secretion: Adhesion Is Mediated by Ig-Like Domain 1

    Article • The Journal of Immunology, October 2001, Oxford University Press (OUP)

    Miguel de la fuente

  52. Molecular characterization and expression of a novel human leukocyte cell-surface marker homologous to mouse Ly-9

    Article • Blood, June 2001, American Society of Hematology

    Miguel de la fuente

  53. Gene structure of the mouse leukocyte cell surface molecule Ly9

    Article • Immunogenetics, August 2000, Springer Science + Business Media

    Miguel de la fuente

  54. Molecular cloning, characterization, and chromosomal localization of the mouse homologue of CD84, a member of the CD2 family of cell surface molecules

    Article • Immunogenetics, March 1999, Springer Science + Business Media

    Miguel de la fuente

  55. CD84 Leukocyte Antigen Is a New Member of the Ig Superfamily

    Article • Blood, September 1997, American Society of Hematology

    Miguel de la fuente

  56. CD148, a membrane protein tyrosine phosphatase, is able to induce tyrosine phosphorylation on human lymphocytes

    Article • Immunology Letters, June 1997, Elsevier

    Miguel de la fuente

  57. Desialylation of T lymphocytes overcomes the monocyte dependency of pokeweed mitogen‐induced T‐cell activation

    Article • Immunology, January 1997, Wiley

    Miguel de la fuente

  58. CD50 (intercellular adhesion molecule‐3) is expressed at higher levels on memory than on naive human T cells but induces a similar calcium mobilization on both subsets

    Article • Tissue Antigens, July 1995, Wiley

    Miguel de la fuente

  59. CD50 (intercellular adhesion molecule 3) stimulation induces calcium mobilization and tyrosine phosphorylation through p59fyn and p56lck in Jurkat T cell line.

    Article • Journal of Experimental Medicine, June 1994, Rockefeller University Press

    Miguel de la fuente

  60. Delayed apperance of anti–myelin‐associated glycoprotein antibodies in a patient with chronic demyelinating polyneuropathy

    Article • Annals of Neurology, September 1993, Wiley

    Miguel de la fuente