All Stories

  1. An In Vitro Human Lens Capsular Bag Model Adopting a Graded Culture Regime to Assess Putative Impact of IOLs on PCO Formation

    Article • Investigative Ophthalmology & Visual Science, January 2019, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  2. Chemopreventive Activities of Sulforaphane and Its Metabolites in Human Hepatoma HepG2 Cells

    Article • Nutrients, May 2018, MDPI AG

    Prof Michael Wormstone

  3. A direct comparison of linear and star-shaped poly(dimethylaminoethyl acrylate) polymers for polyplexation with DNA and cytotoxicity in cultured cell lines

    Article • European Polymer Journal, February 2017, Elsevier

    Prof Michael Wormstone

  4. Sulforaphane promotes ER stress, autophagy, and cell death: implications for cataract surgery

    Article • Journal of Molecular Medicine, January 2017, Springer Science + Business Media

    Prof Michael Wormstone

  5. PARP-1 inhibition influences the oxidative stress response of the human lens

    Article • Redox Biology, August 2016, Elsevier

    Prof Michael Wormstone

  6. wormstone

    Article • Scientific Reports, April 2016, Nature

    Prof Michael Wormstone

  7. Improving the drug development process by reducing the impact of adverse events: the case of cataracts considered

    Article • Drug Discovery Today, March 2016, Elsevier

    Prof Michael Wormstone

  8. AGEs in human lens capsule promote the TGFβ2‐mediated EMT of lens epithelial cells: implications for age‐associated fibrosis

    Article • Aging Cell, February 2016, Wiley

    Prof Michael Wormstone

  9. Experimental models for posterior capsule opacification research

    Article • Experimental Eye Research, January 2016, Elsevier

    Prof Michael Wormstone

  10. Ku80 Counters Oxidative Stress–Induced DNA Damage and Cataract Formation in the Human Lens

    Article • Investigative Ophthalmology & Visual Science, December 2015, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  11. An In Vitro Evaluation of the Anew Zephyr Open-Bag IOL in the Prevention of Posterior Capsule Opacification Using a Human Capsular Bag Model

    Article • Investigative Ophthalmology & Visual Science, November 2014, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  12. Effect of total lens epithelial cell destruction on intraocular lens fixation in the human capsular bag

    Article • Journal of Cataract & Refractive Surgery, February 2014, Elsevier

    Prof Michael Wormstone

  13. Fibrotic Modifications of the Lens Epithelium

    Article • January 2014, Springer Science + Business Media

    Prof Michael Wormstone

  14. Sulforaphane Can Protect Lens Cells Against Oxidative Stress: Implications for Cataract Prevention

    Article • Investigative Ophthalmology & Visual Science, August 2013, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  15. Serum Deprivation Can Suppress Receptor-Mediated Calcium Signaling in Pterygial-Derived Fibroblasts

    Article • Investigative Ophthalmology & Visual Science, July 2013, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  16. Age-Related Differences in Signaling Efficiency of Human Lens Cells Underpin Differential Wound Healing Response Rates following Cataract Surgery

    Article • Investigative Ophthalmology & Visual Science, January 2013, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  17. Sigma 1 receptor stimulation protects against oxidative damage through suppression of the ER stress responses in the human lens

    Article • Mechanisms of Ageing and Development, November 2012, Elsevier

    Prof Michael Wormstone

  18. MMP2 Activity is Critical for TGFβ2-Induced Matrix Contraction—Implications for Fibrosis

    Article • Investigative Ophthalmology & Visual Science, June 2012, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  19. A Fully Human In Vitro Capsular Bag Model to Permit Intraocular Lens Evaluation

    Article • Investigative Ophthalmology & Visual Science, January 2012, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  20. Activation of the innate immune response and interferon signalling in myotonic dystrophy type 1 and type 2 cataracts

    Article • Human Molecular Genetics, November 2011, Oxford University Press (OUP)

    Prof Michael Wormstone

  21. The lens as a model for fibrotic disease

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, March 2011, Royal Society Publishing

    Prof Michael Wormstone

  22. The ocular lens: a classic model for development, physiology and disease

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, March 2011, Royal Society Publishing

    Prof Michael Wormstone

  23. Posterior Capsule Opacification

    Article • January 2010, Elsevier

    Prof Michael Wormstone

  24. TGFβ/Smad4-Dependent and -Independent Regulation of Human Lens Epithelial Cells

    Article • Investigative Ophthalmology & Visual Science, November 2009, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  25. Regional Differences in Store-Operated Ca2+Entry in the Epithelium of the Intact Human Lens

    Article • Investigative Ophthalmology & Visual Science, September 2009, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  26. Predictive in vitro models of in vivo cataract formation by an H3-receptor antagonist

    Article • Toxicology Letters, September 2009, Elsevier

    Prof Michael Wormstone

  27. Posterior capsule opacification

    Article • Experimental Eye Research, February 2009, Elsevier

    Prof Michael Wormstone

  28. The Guardian Obituary: George Duncan, Cell physiologist at the core of research into eye conditions

    Article • Experimental Eye Research, February 2009, Elsevier

    Prof Michael Wormstone

  29. TGFβ-Induced Contraction Is Not Promoted by Fibronectin-Fibronectin Receptor Interaction, or αSMA Expression

    Article • Investigative Ophthalmology & Visual Science, February 2008, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  30. Arsenic trioxide initiates ER stress responses, perturbs calcium signalling and promotes apoptosis in human lens epithelial cells

    Article • Experimental Eye Research, December 2007, Elsevier

    Prof Michael Wormstone

  31. MMP and TIMP Expression in Quiescent, Dividing, and Differentiating Human Lens Cells

    Article • Investigative Ophthalmology & Visual Science, September 2007, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  32. Lens Cell Survival after Exposure to Stress in the Closed Capsular Bag

    Article • Investigative Ophthalmology & Visual Science, June 2007, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  33. TGFβ isoform dependent Smad2/3 kinetics in human lens epithelial cells: A Cellomics analysis

    Article • Experimental Eye Research, May 2007, Elsevier

    Prof Michael Wormstone

  34. The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter

    Article • Nucleic Acids Research, January 2007, Oxford University Press (OUP)

    Prof Michael Wormstone

  35. Short-term exposure to transforming growth factor β induces long-term fibrotic responses

    Article • Experimental Eye Research, November 2006, Elsevier

    Prof Michael Wormstone

  36. A focus on the human lens in vitro

    Article • Environmental Toxicology and Pharmacology, February 2006, Elsevier

    Prof Michael Wormstone

  37. Growth factor receptor signalling in human lens cells: role of the calcium store

    Article • Experimental Eye Research, June 2005, Elsevier

    Prof Michael Wormstone

  38. Regional Differences in Tyrosine Kinase Receptor Signaling Components Determine Differential Growth Patterns in the Human Lens

    Article • Investigative Ophthalmology & Visual Science, May 2004, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  39. Characterisation of TGF-β2 signalling and function in a human lens cell line

    Article • Experimental Eye Research, March 2004, Elsevier

    Prof Michael Wormstone

  40. Spatial Characteristics of Receptor-Induced Calcium Signaling in Human Lens Capsular Bags

    Article • Investigative Ophthalmology & Visual Science, January 2004, Association for Research in Vision and Ophthalmology (ARVO)

    Prof Michael Wormstone

  41. Stress-induced ATP release from and growth modulation of human lens and retinal pigment epithelial cells

    Article • Biochemical Society Transactions, December 2003, Portland Press Ltd.

    Prof Michael Wormstone

  42. Posterior Capsule Opacification: A Cell Biological Perspective

    Article • Experimental Eye Research, March 2002, Elsevier

    Prof Michael Wormstone

  43. Pterygial Derived Fibroblasts Express Functionally Active Histamine and Epidermal Growth Factor Receptors

    Article • Experimental Eye Research, February 2002, Elsevier

    Prof Michael Wormstone

  44. Induction of Matrix Metalloproteinases 2 and 9 following Stress to the Lens

    Article • Experimental Eye Research, December 2000, Elsevier

    Prof Michael Wormstone

  45. Ex vivo canine lens capsular sac explants

    Article • Graefe s Archive for Clinical and Experimental Ophthalmology, August 2000, Springer Science + Business Media

    Prof Michael Wormstone

  46. Calcium cell signalling and cataract: Role of the endoplasmic reticulum

    Article • Eye, May 1999, Nature

    Prof Michael Wormstone

  47. Research Note: Ultraviolet Irradiation (UVB) Interrupts Calcium Cell Signaling in Lens Epithelial Cells

    Article • Photochemistry and Photobiology, May 1999, Wiley

    Prof Michael Wormstone

  48. Ultraviolet Irradiation (UVB) Interrupts Calcium Cell Signaling in Lens Epithelial Cells

    Article • Photochemistry and Photobiology, January 1999, Wiley

    Prof Michael Wormstone

  49. Transferrin in After-Cataract and as a Survival Factor for Lens Epithelium

    Article • Experimental Eye Research, February 1998, Elsevier

    Prof Michael Wormstone

  50. The aging human lens: structure, growth, and physiological behaviour

    Article • British Journal of Ophthalmology, October 1997, BMJ

    Prof Michael Wormstone

  51. Phacoemulsification versus extracapsular cataract extraction: a comparative study of cell survival and growth on the human capsular bag in vitro

    Article • British Journal of Ophthalmology, October 1997, BMJ

    Prof Michael Wormstone

  52. Thapsigargin-coated intraocular lenses inhibit human lens cell growth

    Article • Nature Reports Stem Cells, September 1997, Nature

    Prof Michael Wormstone

  53. Estimation of intracellular calcium activity in confluent monolayers of primary cultures of quail medullary bone osteoclasts

    Article • Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, November 1994, Wiley

    Prof Michael Wormstone