All Stories

  1. conversion of esters to amides in liquid ammonia at high temperature

    Article • Catalysis Science & Technology, July 2014, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  2. pH and basicity of ligands control the binding of metal-ions to B. cereus B1 β-lactamase

    Article • Chemical Science, January 2014, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  3. The ammonolysis of esters in liquid ammonia

    Article • Journal of Physical Organic Chemistry, July 2013, Wiley

    Professor MICHAEL I PAGE

  4. Reaction kinetics in liquid ammonia up to 120°C: techniques and some solvolysis and substitution reactions

    Article • Journal of Physical Organic Chemistry, July 2013, Wiley

    Professor MICHAEL I PAGE

  5. ChemInform Abstract: Copper‐Catalyzed Azide—Alkyne Cycloaddition (CuAAC) in Liquid Ammonia.

    Article • ChemInform, March 2013, Wiley

    Professor MICHAEL I PAGE

  6. ChemInform Abstract: Copper(I)‐Catalyzed Amination of Aryl Halides in Liquid Ammonia.

    Article • ChemInform, December 2012, Wiley

    Professor MICHAEL I PAGE

  7. ChemInform Abstract: Organic Reactivity in Liquid Ammonia

    Article • ChemInform, October 2012, Wiley

    Professor MICHAEL I PAGE

  8. Copper(I)-Catalyzed Amination of Aryl Halides in Liquid Ammonia

    Article • The Journal of Organic Chemistry, August 2012, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  9. Reactive intermediates in the H-phosphonate synthesis of oligonucleotides

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  10. Copper catalysed azide–alkyne cycloaddition (CuAAC) in liquid ammonia

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  11. Organic reactivity in liquid ammonia

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  12. Beta-Lactam Antibiotics

    Article • November 2011, Springer Science + Business Media

    Professor MICHAEL I PAGE

  13. Ionization of Carbon Acids in Liquid Ammonia

    Article • Organic Letters, October 2011, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  14. The Kinetics and Mechanisms of Aromatic Nucleophilic Substitution Reactions in Liquid Ammonia

    Article • The Journal of Organic Chemistry, March 2011, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  15. Anti-inflammatory actions of a taurine analogue, ethane β-sultam, in phagocytic cells, in vivo and in vitro

    Article • Biochemical Pharmacology, March 2011, Elsevier

    Professor MICHAEL I PAGE

  16. Liquid Ammonia as a Dipolar Aprotic Solvent for Aliphatic Nucleophilic Substitution Reactions

    Article • The Journal of Organic Chemistry, February 2011, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  17. The kinetics and mechanisms of organic reactions in liquid ammonia

    Article • Faraday Discussions, January 2010, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  18. The kinetics and mechanism of the acid-catalysed detritylation of nucleotides in non-aqueous solution

    Article • Organic & Biomolecular Chemistry, January 2009, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  19. The mechanism of the phosphoramidite synthesis of polynucleotides

    Article • Organic & Biomolecular Chemistry, January 2008, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  20. Catalytic Racemisation of Chiral Amines and Application in Dynamic Kinetic Resolution

    Article • Organic Process Research & Development, May 2007, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  21. Chemoenzymatic dynamic kinetic resolution of secondary amines

    Article • Tetrahedron Letters, February 2007, Elsevier

    Professor MICHAEL I PAGE

  22. The aminolysis of N-aroyl β-lactams occurs by a concerted mechanism

    Article • Organic & Biomolecular Chemistry, January 2007, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  23. Inhibitors of Metallo-β-lactamase Generated from β-Lactam Antibiotics

    Article • Biochemistry, May 2005, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  24. β‐Sultams — Mechanism of Reactions and Use as Inhibitors of Serine Proteases

    Article • ChemInform, July 2004, Wiley

    Professor MICHAEL I PAGE

  25. Intramolecular general acid catalysis in the aminolysis of β-lactam antibiotics

    Article • Organic & Biomolecular Chemistry, January 2004, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  26. Novel mechanism of inhibiting β-Lactamases by sulfonylation using β-Sultams

    Article • Bioorganic & Medicinal Chemistry Letters, December 2003, Elsevier

    Professor MICHAEL I PAGE

  27. Hydrolysis of a sulfonamide by a novel elimination mechanism generated by carbanion formation in the leaving group

    Article • Chemical Communications, March 2002, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  28. Reactivity and Mechanism in the Hydrolysis of β-Sultams

    Article • Journal of the American Chemical Society, March 2000, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  29. ChemInform Abstract: The Reactivity of β‐Lactams, the Mechanism of Catalysis and the Inhibition of β‐Lactamases

    Article • ChemInform, February 2000, Wiley

    Professor MICHAEL I PAGE

  30. Chemical Reactivity of Penicillins and Cephalosporins. Intramolecular Involvement of the Acyl-Amido Side Chain

    Article • The Journal of Organic Chemistry, November 1998, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  31. The mechanism of catalysis and the inhibition of β-lactamases

    Article • Chemical Communications, January 1998, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  32. Mechanism of hydrolysis of coumaran-2-ones

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1998, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  33. ChemInform Abstract: An Unexpected Mitsunobu Reaction. A Direct Route to the 2,5‐ Diazabicyclo(2.2.1)heptan‐3‐one Skeleton as a γ‐Lactam Mimic of . beta.‐Lactam Antibiotics.

    Article • ChemInform, July 1997, Wiley

    Professor MICHAEL I PAGE

  34. An unexpected Mitsunobu reaction. A direct route to the 2,5-diazabicyclo[2.2.1]heptan-3-one skeleton as a γ-lactam mimic of β-lactam antibiotics

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1997, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  35. The mechanism of reactions catalysed by the serine β-lactamases

    Article • Bioorganic & Medicinal Chemistry Letters, November 1993, Elsevier

    Professor MICHAEL I PAGE

  36. ChemInform Abstract: The Mechanisms of Hydrolysis of the γ‐Lactam Isatin (I) and Its Derivatives.

    Article • ChemInform, April 1993, Wiley

    Professor MICHAEL I PAGE

  37. The mechanisms of hydrolysis of the γ-lactam isatin and its derivatives

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1993, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  38. The roles of the carboxy group in β-lactam antibiotics and lysine 234 in β-lactamase I

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1993, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  39. The esterase catalysed resolution of lactones and spirodilactone

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1993, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  40. The resolution of racemic 1,2-diols by the esterase catalysed hydrolysis of the corresponding cyclic carbonate

    Article • Tetrahedron, September 1992, Elsevier

    Professor MICHAEL I PAGE

  41. The Chemistry of β-Lactams

    Article • January 1992, Springer Science + Business Media

    Professor MICHAEL I PAGE

  42. The effect of the carboxy group on the chemical and β-lactamase reactivity of β-lactam antibiotics

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1989, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  43. Energy differences and their relevance to enzyme and intramolecular catalysis

    Article • Journal of Molecular Catalysis, September 1988, Elsevier

    Professor MICHAEL I PAGE

  44. The Mechanisms of Reactions of β-Lactam Antibiotics

    Article • January 1987, Elsevier

    Professor MICHAEL I PAGE

  45. Stereochemical studies. Part 112. Geometrical dependence of intramolecular catalysis in the hydrolysis and aminolysis of aryl esters

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1986, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  46. Mechanism of .beta.-lactam ring opening in cephalosporins

    Article • Journal of the American Chemical Society, June 1984, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  47. The mechanisms of reactions of .beta.-lactam antibiotics

    Article • Accounts of Chemical Research, April 1984, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  48. Chapter 1 The energetics and specificity of enzyme—substrate interactions

    Article • January 1984, Elsevier

    Professor MICHAEL I PAGE

  49. The chemical reactivity of penicillins and other β-lactam antibiotics

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1982, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  50. Metal-ion catalysed hydrolysis of some β-lactam antibiotics

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1980, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  51. The mechanism of nitrosation of 4-nitrophenol with aqueous nitrous acid

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1980, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  52. Intramolecular nucleophilic and general acid catalysis in the hydrolysis of an amide. Some comments on the mechanism of catalysis by serine proteases

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1980, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  53. Intramolecular general acid catalysis in the aminolysis of benzylpenicillin. A preferred direction of nucleophilic attack

    Article • Journal of the Chemical Society Chemical Communications, January 1979, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  54. Intramolecular nucleophilic and general acid catalysis in the hydrolysis of an amide

    Article • Journal of the Chemical Society Chemical Communications, January 1978, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  55. “Orbital steering”, entropy, and rate accelerations

    Article • Biochemical and Biophysical Research Communications, April 1974, Elsevier

    Professor MICHAEL I PAGE

  56. Intramolecular general acid catalysis in the halogenation of ketones

    Article • Journal of the Chemical Society Perkin Transactions 2, January 1973, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  57. The energetics of neighbouring group participation

    Article • Chemical Society Reviews, January 1973, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  58. Intramolecular general base catalysis in the aminolysis of acetylimidazole and methyl formate by diamines

    Article • Journal of the American Chemical Society, December 1972, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  59. General base and acid catalysis in the hydrazinolysis of acetylimidazole

    Article • Journal of the American Chemical Society, December 1972, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  60. Nonlinear broensted relation for general acid-base catalysis of aminolysis reactions

    Article • Journal of the American Chemical Society, June 1972, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  61. Uncatalyzed aminolysis of acetylimidazole. Limiting product-like transition state for acyl transfer

    Article • Journal of the American Chemical Society, May 1972, American Chemical Society (ACS)

    Professor MICHAEL I PAGE

  62. Entropic Contributions to Rate Accelerations in Enzymic and Intramolecular Reactions and the Chelate Effect

    Article • Proceedings of the National Academy of Sciences, August 1971, Proceedings of the National Academy of Sciences

    Professor MICHAEL I PAGE

  63. The kinetics and mechanism of the hydrolysis of esters of cis- and trans-2-hydroxycyclopentanecarboxylic acid and 3-hydroxybutyric acid

    Article • Journal of the Chemical Society B Physical Organic, January 1971, Royal Society of Chemistry

    Professor MICHAEL I PAGE

  64. Reactions of Acids and Their Derivatives

    Article • Wiley

    Professor MICHAEL I PAGE

  65. Reactions of Acids and their Derivatives

    Article • Wiley

    Professor MICHAEL I PAGE

  66. Reactions of Acids and their Derivatives

    Article • Wiley

    Professor MICHAEL I PAGE