All Stories

  1. KSHV infection of endothelial precursor cells with lymphatic characteristics as a novel model for translational Kaposi’s sarcoma studies

    Article • PLoS Pathogens, January 2023, PLOS

    Professor Michael Lagunoff, Krista Tuohinto

  2. A CRISPR-Cas9 screen identifies mitochondrial translation as an essential process in latent KSHV infection of human endothelial cells

    Article • Proceedings of the National Academy of Sciences, October 2020, Proceedings of the National Academy of Sciences

    Professor Michael Lagunoff

  3. KSHV requires vCyclin to overcome replicative senescence in primary human lymphatic endothelial cells

    Article • PLoS Pathogens, June 2020, PLOS

    Professor Michael Lagunoff

  4. Quantitative Analysis of the KSHV Transcriptome Following Primary Infection of Blood and Lymphatic Endothelial Cells

    Article • Pathogens, March 2017, MDPI AG

    Professor Michael Lagunoff

  5. Glycolysis, Glutaminolysis, and Fatty Acid Synthesis Are Required for Distinct Stages of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication

    Article • Journal of Virology, March 2017, ASM Journals

    Professor Michael Lagunoff

  6. Integrated systems biology analysis of KSHV latent infection reveals viral induction and reliance on peroxisome mediated lipid metabolism

    Article • PLoS Pathogens, March 2017, PLOS

    Professor Michael Lagunoff

  7. Activation of cellular metabolism during latent Kaposi's Sarcoma herpesvirus infection

    Article • Current Opinion in Virology, August 2016, Elsevier

    Professor Michael Lagunoff

  8. Isolation and characterization of circulating lymphatic endothelial colony forming cells

    Article • Experimental Cell Research, January 2016, Elsevier

    Professor Michael Lagunoff

  9. Latent KSHV Infected Endothelial Cells Are Glutamine Addicted and Require Glutaminolysis for Survival

    Article • PLoS Pathogens, July 2015, PLOS

    Professor Michael Lagunoff

  10. Viral activation of cellular metabolism

    Article • Virology, May 2015, Elsevier

    Professor Michael Lagunoff

  11. KSHV-TK: thymidine kinase or tyrosine kinase?

    Article • The EMBO Journal, January 2015, EMBO

    Professor Michael Lagunoff

  12. Nelfinavir Impairs Glycosylation of Herpes Simplex Virus 1 Envelope Proteins and Blocks Virus Maturation

    Article • Advances in Virology, January 2015, Hindawi Publishing Corporation

    Professor Michael Lagunoff

  13. Dengue Virus Induces and Requires Glycolysis for Optimal Replication

    Article • Journal of Virology, December 2014, ASM Journals

    Professor Michael Lagunoff

  14. Kaposi's Sarcoma-Associated Herpesvirus Downregulates Transforming Growth Factor  2 To Promote Enhanced Stability of Capillary-Like Tube Formation

    Article • Journal of Virology, October 2014, ASM Journals

    Professor Michael Lagunoff

  15. Nuclear factor kappa B is required for the production of infectious human herpesvirus 8 virions

    Article • Frontiers in Microbiology, April 2014, Frontiers

    Professor Michael Lagunoff

  16. Vaccinia Virus Requires Glutamine but Not Glucose for Efficient Replication

    Article • Journal of Virology, February 2014, ASM Journals

    Professor Michael Lagunoff

  17. Ets-1 Is Required for the Activation of VEGFR3 during Latent Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells

    Article • Journal of Virology, April 2013, ASM Journals

    Professor Michael Lagunoff

  18. Global Metabolic Profiling of Infection by an Oncogenic Virus: KSHV Induces and Requires Lipogenesis for Survival of Latent Infection

    Article • PLoS Pathogens, August 2012, PLOS

    Professor Michael Lagunoff

  19. The KSHV viral IL-6 homolog is sufficient to induce blood to lymphatic endothelial cell differentiation

    Article • Virology, July 2012, Elsevier

    Professor Michael Lagunoff

  20. ANGIOGENIC AND ONCOGENIC ALTERATIONS OF ENDOTHELIAL CELLS BY KSHV

    Article • March 2012, World Scientific Pub Co Pte Lt

    Professor Michael Lagunoff

  21. KSHV Induction of Angiogenic and Lymphangiogenic Phenotypes

    Article • Frontiers in Microbiology, January 2012, Frontiers

    Professor Michael Lagunoff

  22. Latent KSHV Infection of Endothelial Cells Induces Integrin Beta3 to Activate Angiogenic Phenotypes

    Article • PLoS Pathogens, December 2011, PLOS

    Professor Michael Lagunoff

  23. The HIV Protease Inhibitor Nelfinavir Inhibits Kaposi's Sarcoma-Associated Herpesvirus Replication In Vitro

    Article • Antimicrobial Agents and Chemotherapy, March 2011, ASM Journals

    Professor Michael Lagunoff

  24. Induction of the Warburg effect by Kaposi's sarcoma herpesvirus is required for the maintenance of latently infected endothelial cells

    Article • Proceedings of the National Academy of Sciences, May 2010, Proceedings of the National Academy of Sciences

    Professor Michael Lagunoff

  25. Activation of Akt through gp130 Receptor Signaling Is Required for Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphatic Reprogramming of Endothelial Cells

    Article • Journal of Virology, June 2008, ASM Journals

    Professor Michael Lagunoff

  26. CD8 T Cell Control of HSV Reactivation from Latency Is Abrogated by Viral Inhibition of MHC Class I

    Article • Cell Host & Microbe, September 2007, Elsevier

    Professor Michael Lagunoff

  27. The KSHV viral interleukin-6 is not essential for latency or lytic replication in BJAB cells

    Article • Virology, March 2007, Elsevier

    Professor Michael Lagunoff

  28. Persistent Activation of STAT3 by Latent Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells

    Article • Journal of Virology, December 2006, ASM Journals

    Professor Michael Lagunoff

  29. The insulin receptor is essential for virus-induced tumorigenesis of Kaposi's sarcoma

    Article • Oncogene, September 2006, Nature

    Professor Michael Lagunoff

  30. Latent Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells Activates Hypoxia-Induced Factors

    Article • Journal of Virology, September 2006, ASM Journals

    Professor Michael Lagunoff

  31. Kaposi's sarcoma-associated herpesvirus infection of blood endothelial cells induces lymphatic differentiation

    Article • Virology, October 2004, Elsevier

    Professor Michael Lagunoff

  32. INHIBITION OF APOPTOSIS BY THE γ-HERPESVIRUSES

    Article • International Reviews of Immunology, January 2003, Taylor & Francis

    Professor Michael Lagunoff

  33. Synthesis and studies of cis-Mo(CO)2(L–L′)2 and Mo(L–L′)3 complexes of 2-(phenylazo)pyridines (L–L′) and the crystal structures of Mo(CO)2(4-methyl-2-(phenylazo)pyridine)2 and Mo(4-methyl-2-(phenylazo)pyridine)3

    Article • Inorganica Chimica Acta, May 2002, Elsevier

    Professor Michael Lagunoff

  34. De Novo Infection and Serial Transmission of Kaposi's Sarcoma-Associated Herpesvirus in Cultured Endothelial Cells

    Article • Journal of Virology, March 2002, ASM Journals

    Professor Michael Lagunoff

  35. Immunoreceptor Tyrosine-Based Activation Motif-Dependent Signaling by Kaposi's Sarcoma-Associated Herpesvirus K1 Protein: Effects on Lytic Viral Replication

    Article • Journal of Virology, July 2001, ASM Journals

    Professor Michael Lagunoff

  36. Herpes Simplex Virus 1 Open Reading Frames O and P Are Not Necessary for Establishment of Latent Infection in Mice

    Article • Journal of Virology, October 2000, ASM Journals

    Professor Michael Lagunoff

  37. Deregulated signal transduction by the K1 gene product of Kaposi’s sarcoma-associated herpesvirus

    Article • Proceedings of the National Academy of Sciences, May 1999, Proceedings of the National Academy of Sciences

    Professor Michael Lagunoff

  38. EXPRESSION OF LATENT HHV-8 GENES

    Article • Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology, April 1998, Wolters Kluwer Health

    Professor Michael Lagunoff

  39. Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus.

    Article • Journal of Clinical Investigation, November 1997, American Society for Clinical Investigation

    Professor Michael Lagunoff

  40. The product of ORF O located within the domain of herpes simplex virus 1 genome transcribed during latent infection binds to and inhibits in vitro binding of infected cell protein 4 to its cognate DNA site

    Article • Proceedings of the National Academy of Sciences, September 1997, Proceedings of the National Academy of Sciences

    Professor Michael Lagunoff

  41. The Structure and Coding Organization of the Genomic Termini of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8)

    Article • Virology, September 1997, Elsevier

    Professor Michael Lagunoff