All Stories

  1. Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy

    Article • PLoS Pathogens, July 2021, PLOS

    Michael Gale, Jr.

  2. Spatiotemporal dynamics of innate immune signaling via RIG-I–like receptors

    Article • Proceedings of the National Academy of Sciences, June 2020, Proceedings of the National Academy of Sciences

    Michael Gale, Jr.

  3. RIG-I-like receptor activation drives type I IFN and antiviral signaling to limit Hantaan orthohantavirus replication

    Article • PLoS Pathogens, April 2020, PLOS

    Michael Gale, Jr.

  4. STING is required for host defense against neuropathological West Nile virus infection

    Article • PLoS Pathogens, August 2019, PLOS

    Michael Gale, Jr.

  5. Modulation of calcium signaling pathway by hepatitis C virus core protein stimulates NLRP3 inflammasome activation

    Article • PLoS Pathogens, February 2019, PLOS

    Michael Gale, Jr.

  6. Interleukin-1β Signaling in Dendritic Cells Induces Antiviral Interferon Responses

    Article • mBio, March 2018, ASM Journals

    Michael Gale, Jr.

  7. Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway

    Article • Journal of Virology, December 2015, ASM Journals

    Michael Gale, Jr.

  8. Pathogen-Associated Molecular Pattern Recognition of Hepatitis C Virus Transmitted/Founder Variants by RIG-I Is Dependent on U-Core Length

    Article • Journal of Virology, August 2015, ASM Journals

    Michael Gale, Jr.

  9. Genetic Diversity in the Collaborative Cross Model Recapitulates Human West Nile Virus Disease Outcomes

    Article • mBio, May 2015, ASM Journals

    Michael Gale, Jr.

  10. Deficient IFN Signaling by Myeloid Cells Leads to MAVS-Dependent Virus-Induced Sepsis

    Article • PLoS Pathogens, April 2014, PLOS

    Michael Gale, Jr.

  11. Regulation of Innate Immunity by the Flaviviridae

    Article • April 2014, ASM Journals

    Michael Gale, Jr.

  12. Innate Antiviral Immune Signaling, Viral Evasion and Modulation by HIV-1

    Article • Journal of Molecular Biology, March 2014, Elsevier

    Michael Gale, Jr.

  13. 205

    Article • Cytokine, September 2013, Elsevier

    Michael Gale, Jr.

  14. The Essential, Nonredundant Roles of RIG-I and MDA5 in Detecting and Controlling West Nile Virus Infection

    Article • Journal of Virology, August 2013, ASM Journals

    Michael Gale, Jr.

  15. West Nile virus infection and immunity

    Article • Nature Reviews Microbiology, January 2013, Springer Science + Business Media

    Michael Gale, Jr.

  16. Sterol-izing Innate Immunity

    Article • Immunity, January 2013, Elsevier

    Michael Gale, Jr.

  17. Cell-intrinsic innate immune control of West Nile virus infection

    Article • Trends in Immunology, October 2012, Elsevier

    Michael Gale, Jr.

  18. RIG-I Like Receptors in Antiviral Immunity and Therapeutic Applications

    Article • Viruses, June 2011, MDPI AG

    Michael Gale, Jr.

  19. Immune Signaling by RIG-I-like Receptors

    Article • Immunity, May 2011, Elsevier

    Michael Gale, Jr.

  20. Characterizing the Role of LGP2 in RLR Signaling and Anti-Viral Immunity

    Article • Journal of Allergy and Clinical Immunology, February 2011, Elsevier

    Michael Gale, Jr.

  21. 2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

    Article • Nature, November 2010, Springer Science + Business Media

    Michael Gale, Jr., Volker Fensterl

  22. CS4-1 PAMP signaling and mechanisms of IFN actions against virus infection

    Article • Cytokine, October 2010, Elsevier

    Michael Gale, Jr.

  23. PS3-09 An RNase L mediated cleavage product of hepatitis C virus RNA requires a 3′-

    Article • Cytokine, October 2010, Elsevier

    Michael Gale, Jr.

  24. PS1-18 West Nile Virus infection primes IL-12 and T-bet independent IFN-γ production from antigen specific CD8+ T cells

    Article • Cytokine, October 2010, Elsevier

    Michael Gale, Jr.

  25. SS4-5 Viral regulation of a TLR/RLR-independent program of host cell recognition of HIV-1 infection

    Article • Cytokine, October 2010, Elsevier

    Michael Gale, Jr.

  26. PS2-75 Regulation of the response to interferon therapy through innate immune tolerance during hepatitis C virus infection

    Article • Cytokine, October 2010, Elsevier

    Michael Gale, Jr.

  27. Pegylated Interferon and Ribavirin Promote Early Evolution of Nonstructural 5A Protein in Individuals with Hepatitis C Who Demonstrate a Response to Treatment

    Article • The Journal of Infectious Diseases, September 2009, Oxford University Press (OUP)

    Michael Gale, Jr.

  28. Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses

    Article • Cellular Microbiology, June 2009, Hindawi Publishing Corporation

    Michael Gale, Jr.

  29. Fighting the Flu with Inflammasome Signaling

    Article • Immunity, April 2009, Elsevier

    Michael Gale, Jr.

  30. Measure and Countermeasure: Type I IFN (IFN-α/β) Antiviral Response against West Nile Virus

    Article • Journal of Innate Immunity, January 2009, Karger Publishers

    Michael Gale, Jr.

  31. Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

    Article • Nature, July 2008, Springer Science + Business Media

    Michael Gale, Jr., Takeshi Saito

  32. RIG-I mediated hepatic innate immune signaling that controls HCV infection.

    Article • Uirusu, January 2008, Japanese Association of Virology

    Michael Gale, Jr.

  33. Fatal immunity and the 1918 virus

    Article • Nature, January 2007, Springer Science + Business Media

    Michael Gale, Jr.

  34. Reemergence of Hepatitis C Virus after 8.5 Years in a Patient with Hypogammaglobulinemia: Evidence for an Occult Viral Reservoir

    Article • The Journal of Infectious Diseases, September 2005, Oxford University Press (OUP)

    Michael Gale, Jr.

  35. Identification of FBL2 As a Geranylgeranylated Cellular Protein Required for Hepatitis C Virus RNA Replication

    Article • Molecular Cell, May 2005, Elsevier

    Michael Gale, Jr.

  36. Strategies for hepatitis C therapeutic intervention: now and next

    Article • Current Opinion in Pharmacology, October 2004, Elsevier

    Michael Gale, Jr.

  37. Viruses and interferon: a fight for supremacy

    Article • Nature Reviews Immunology, September 2002, Springer Science + Business Media

    Michael Gale, Jr.

  38. Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: a potential mechanism of interferon resistance

    Article • Clinical and Diagnostic Virology, July 1998, Elsevier

    Michael Gale, Jr.