All Stories

  1. The rarA gene as part of an expanded RecFOR recombination pathway: Negative epistasis and synthetic lethality with ruvB, recG, and recQ

    Article • PLoS Genetics, December 2021, PLOS

    Dr Michael M Cox

  2. RecA‐independent recombination: Dependence on the Escherichia coli RarA protein

    Article • Molecular Microbiology, December 2020, Wiley

    Dr Michael M Cox

  3. Escherichia coli Genes and Pathways Involved in Surviving Extreme Exposure to Ionizing Radiation

    Article • Journal of Bacteriology, July 2014, ASM Journals

    Dr Michael M Cox

  4. The RecA Protein

    Article • April 2014, ASM Journals

    Dr Michael M Cox

  5. DNA polymerase V activity is autoregulated by a novel intrinsic DNA-dependent ATPase

    Article • eLife, April 2014, eLife

    Dr Michael M Cox

  6. Evolution of extreme resistance to ionizing radiation via genetic adaptation of DNA repair

    Article • eLife, March 2014, eLife

    Dr Michael M Cox

  7. Proteins pinpoint double strand breaks

    Article • eLife, October 2013, eLife

    Dr Michael M Cox

  8. Regulation of Deinococcus radiodurans RecA Protein Function via Modulation of Active and Inactive Nucleoprotein Filament States

    Article • Journal of Biological Chemistry, May 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  9. Investigating Deinococcus radiodurans RecA Protein Filament Formation on Double-Stranded DNA by a Real-Time Single-Molecule Approach

    Article • Biochemistry, September 2011, American Chemical Society (ACS)

    Dr Michael M Cox

  10. Developing Single-Molecule TPM Experiments for Direct Observation of Successful RecA-Mediated Strand Exchange Reaction

    Article • PLoS ONE, July 2011, PLOS

    Dr Michael M Cox

  11. Two Modes of Binding of DinI to RecA Filament Provide a New Insight into the Regulation of SOS Response by DinI Protein

    Article • Journal of Molecular Biology, May 2011, Elsevier

    Dr Michael M Cox

  12. Purification and Characterization of the RecA Protein from Neisseria gonorrhoeae

    Article • PLoS ONE, February 2011, PLOS

    Dr Michael M Cox

  13. Using Real-Time, Single-Molecule Experiments to Monitor Reca-Mediated Pairing and Strand Exchange Reactions at Various Nucleotide States

    Article • Biophysical Journal, February 2011, Elsevier

    Dr Michael M Cox

  14. Creating Directed Double-strand Breaks with the Ref Protein: A NOVEL RecA-DEPENDENT NUCLEASE FROM BACTERIOPHAGE P1

    Article • Journal of Biological Chemistry, December 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  15. Modulating cellular recombination potential through alterations in RecA structure and regulation

    Article • Molecular Microbiology, October 2010, Wiley

    Dr Michael M Cox

  16. Less Is More: Neisseria gonorrhoeae RecX Protein Stimulates Recombination by Inhibiting RecA

    Article • Journal of Biological Chemistry, September 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  17. A new model for SOS-induced mutagenesis: how RecA protein activates DNA polymerase V

    Article • Critical Reviews in Biochemistry and Molecular Biology, May 2010, Taylor & Francis

    Dr Michael M Cox

  18. Investigating the Nucleation and Extension Rates of E.coli and Deinococcus RecA Along Duplex DNA

    Article • Biophysical Journal, January 2010, Elsevier

    Dr Michael M Cox

  19. Using Real-Time, Single-Molecule Experiments To Monitor RecA-Mediated Pairing and Strand Exchange Reactions in Various Nucleotide States

    Article • Biophysical Journal, January 2010, Elsevier

    Dr Michael M Cox

  20. An SOS Inhibitor that Binds to Free RecA Protein: The PsiB Protein

    Article • Molecular Cell, October 2009, Elsevier

    Dr Michael M Cox

  21. The active form of DNA polymerase V is UmuD′2C–RecA–ATP

    Article • Nature, July 2009, Springer Science + Business Media

    Dr Michael M Cox

  22. RecA‐mediated SOS induction requires an extended filament conformation but no ATP hydrolysis

    Article • Molecular Microbiology, August 2008, Wiley

    Dr Michael M Cox

  23. Defective Dissociation of a "Slow" RecA Mutant Protein Imparts an Escherichia coli Growth Defect

    Article • Journal of Biological Chemistry, July 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  24. Two RecA Protein Types That Mediate Different Modes of Hyperrecombination

    Article • Journal of Bacteriology, February 2008, ASM Journals

    Dr Michael M Cox

  25. Motoring along with the bacterial RecA protein

    Article • Nature Reviews Molecular Cell Biology, January 2007, Springer Science + Business Media

    Dr Michael M Cox

  26. The bacterial RecA protein: structure, function, and regulation

    Article • January 2007, Springer Science + Business Media

    Dr Michael M Cox

  27. Regulation of Bacterial RecA Protein Function

    Article • Critical Reviews in Biochemistry and Molecular Biology, January 2007, Taylor & Francis

    Dr Michael M Cox

  28. Distinguishing Characteristics of Hyperrecombinogenic RecA Protein from Pseudomonas aeruginosa Acting in Escherichia coli

    Article • Journal of Bacteriology, August 2006, ASM Journals

    Dr Michael M Cox

  29. RecA acts in trans to allow replication of damaged DNA by DNA polymerase V

    Article • Nature, August 2006, Springer Science + Business Media

    Dr Michael M Cox

  30. Roles of DNA Polymerase V and RecA Protein in SOS Damage‐Induced Mutation

    Article • ChemInform, May 2006, Wiley

    Dr Michael M Cox

  31. Complementation of One RecA Protein Point Mutation by Another: EVIDENCE FOR TRANS CATALYSIS OF ATP HYDROLYSIS

    Article • Journal of Biological Chemistry, March 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  32. Roles of DNA Polymerase V and RecA Protein in SOS Damage-Induced Mutation

    Article • Chemical Reviews, January 2006, American Chemical Society (ACS)

    Dr Michael M Cox

  33. Inhibition of RecA Protein Function by the RdgC Protein from Escherichia coli

    Article • Journal of Biological Chemistry, December 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  34. Organized Unidirectional Waves of ATP Hydrolysis within a RecA Filament

    Article • PLoS Biology, February 2005, PLOS

    Dr Michael M Cox

  35. DNA Polymerase V and RecA Protein, a Minimal Mutasome

    Article • Molecular Cell, February 2005, Elsevier

    Dr Michael M Cox

  36. Inhibition of RecA Protein by the Escherichia coli RecX Protein: MODULATION BY THE RecA C TERMINUS AND FILAMENT FUNCTIONAL STATE

    Article • Journal of Biological Chemistry, October 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  37. A RecA Filament Capping Mechanism for RecX Protein

    Article • Molecular Cell, September 2004, Elsevier

    Dr Michael M Cox

  38. Rec A Protein

    Article • July 2004, Wiley

    Dr Michael M Cox

  39. The DinI Protein Stabilizes RecA Protein Filaments

    Article • Journal of Biological Chemistry, May 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  40. RecA Protein from the Extremely Radioresistant Bacterium Deinococcus radiodurans: Expression, Purification, and Characterization

    Article • Journal of Bacteriology, March 2002, ASM Journals

    Dr Michael M Cox

  41. Faculty Opinions recommendation of Domain structure and dynamics in the helical filaments formed by RecA and Rad51 on DNA.

    Article • November 2001, F1000Research

    Dr Michael M Cox

  42. RecA protein promotes the regression of stalled replication forks in vitro

    Article • Proceedings of the National Academy of Sciences, July 2001, Proceedings of the National Academy of Sciences

    Dr Michael M Cox

  43. RecA Protein Promotes Strand Exchange with DNA Substrates Containing Isoguanine and 5-Methyl Isocytosine

    Article • Biochemistry, July 2000, American Chemical Society (ACS)

    Dr Michael M Cox

  44. Quantitative analysis of the kinetics of end-dependent disassembly of RecA filaments from ssDNA

    Article • Journal of Molecular Biology, May 1999, Elsevier

    Dr Michael M Cox

  45. Recombinational DNA Repair in Bacteria and the RecA Protein

    Article • January 1999, Elsevier

    Dr Michael M Cox

  46. On the Mechanism of RecA-Mediated Repair of Double-Strand Breaks: No Role for Four-Strand DNA Pairing Intermediates

    Article • Molecular Cell, January 1998, Elsevier

    Dr Michael M Cox

  47. Recombinational DNA Repair: The RecF and RecR Proteins Limit the Extension of RecA Filaments beyond Single-Strand DNA Gaps

    Article • Cell, October 1997, Elsevier

    Dr Michael M Cox

  48. RecA as a Motor Protein: TESTING MODELS FOR THE ROLE OF ATP HYDROLYSIS IN DNA STRAND EXCHANGE

    Article • Journal of Biological Chemistry, July 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  49. RecA Filament Dynamics during DNA Strand Exchange Reactions

    Article • Journal of Biological Chemistry, April 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  50. RecA Protein: Structure, Function, and Role in Recombinational DNA Repair

    Article • January 1997, Elsevier

    Dr Michael M Cox

  51. RecA protein filaments: end-dependent dissociation from ssDNA and stabilization by RecO and RecR proteins

    Article • Journal of Molecular Biology, January 1997, Elsevier

    Dr Michael M Cox

  52. Characterization of a Mutant RecA Protein that Facilitates Homologous Genetic Recombination but not Recombinational DNA Repair: RecA423

    Article • Journal of Molecular Biology, December 1996, Elsevier

    Dr Michael M Cox

  53. RecA Protein Dynamics in the Interior of RecA Nucleoprotein Filaments

    Article • Journal of Molecular Biology, April 1996, Elsevier

    Dr Michael M Cox

  54. Evidence for the Coupling of ATP Hydrolysis to the Final (Extension) Phase of RecA Protein-mediated DNA Strand Exchange

    Article • Journal of Biological Chemistry, March 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  55. Alignment of 3 (but Not 4) DNA Strands within a RecA Protein Filament

    Article • Journal of Biological Chemistry, November 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  56. Quantitative RecA Protein Binding to the Hybrid Duplex Product of DNA Strand Exchange

    Article • Biochemistry, August 1995, American Chemical Society (ACS)

    Dr Michael M Cox

  57. Occurrence of Three-stranded DNA within a RecA Protein Filament

    Article • Journal of Biological Chemistry, March 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Michael M Cox

  58. The deduced Vibrio cholerae RecA amino-acid sequence

    Article • Gene, January 1995, Elsevier

    Dr Michael M Cox

  59. Why does RecA protein hydrolyse ATP?

    Article • Trends in Biochemical Sciences, May 1994, Elsevier

    Dr Michael M Cox

  60. Problems and Paradigms: Relating biochemistry to biology: How the recombinational repair function of RecA protein is manifested in its molecular properties

    Article • BioEssays, September 1993, Wiley

    Dr Michael M Cox

  61. The RecA protein as a recombinational repair system

    Article • Molecular Microbiology, June 1991, Wiley

    Dr Michael M Cox

  62. Inhibition of RecA protein promoted ATP hydrolysis. 2. Longitudinal assembly and disassembly of RecA protein filaments mediated by ATP and ADP

    Article • Biochemistry, August 1990, American Chemical Society (ACS)

    Dr Michael M Cox

  63. Inhibition of RecA protein promoted ATP hydrolysis. 1. ATP.gamma.S and ADP are antagonistic inhibitors

    Article • Biochemistry, August 1990, American Chemical Society (ACS)

    Dr Michael M Cox

  64. Stabilization of recA protein-ssDNA complexes by the single-stranded DNA binding protein of Escherichia coli

    Article • Biochemistry, January 1990, American Chemical Society (ACS)

    Dr Michael M Cox

  65. The RecA Protein: Structure and Functio

    Article • Critical Reviews in Biochemistry and Molecular Biology, January 1990, Taylor & Francis

    Dr Michael M Cox

  66. Extent of duplex DNA underwinding induced by RecA protein binding in the presence of ATP

    Article • Journal of Molecular Biology, February 1989, Elsevier

    Dr Michael M Cox

  67. Dissociation pathway for recA nucleoprotein filaments formed on linear duplex DNA

    Article • Journal of Molecular Biology, February 1989, Elsevier

    Dr Michael M Cox

  68. The Role of RecA Protein in Homologous Genetic Recombination

    Article • January 1989, Springer Science + Business Media

    Dr Michael M Cox

  69. Homology-dependent underwinding of duplex DNA in RecA protein generated paranemic complexes

    Article • Biochemistry, October 1988, American Chemical Society (ACS)

    Dr Michael M Cox

  70. General mechanism for RecA protein binding to duplex DNA

    Article • Journal of Molecular Biology, September 1988, Elsevier

    Dr Michael M Cox

  71. Homology-dependent changes in adenosine 5'-triphosphate hydrolysis during recA protein-promoted DNA strand exchange: evidence for long paranemic complexes

    Article • Biochemistry, September 1987, American Chemical Society (ACS)

    Dr Michael M Cox

  72. Continuous association of Escherichia coli single-stranded DNA binding protein with stable complexes of recA protein and single-stranded DNA

    Article • Biochemistry, April 1986, American Chemical Society (ACS)

    Dr Michael M Cox

  73. Light scattering studies of the recA protein of Escherichia coli: relationship between free recA filaments and the recA.cntdot.ssDNA complex

    Article • Biochemistry, January 1985, American Chemical Society (ACS)

    Dr Michael M Cox

  74. Unidirectional Branch Migration Promoted by Nucleoprotein Filaments of RecA Protein and DNA

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1984, Cold Spring Harbor Laboratory Press

    Dr Michael M Cox

  75. DNA Strand Exchange Promoted by recA Protein and Single-stranded DNA-binding Protein of Escherichia coli

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1983, Cold Spring Harbor Laboratory Press

    Dr Michael M Cox

  76. Directionality and polarity in recA protein-promoted branch migration.

    Article • Proceedings of the National Academy of Sciences, October 1981, Proceedings of the National Academy of Sciences

    Dr Michael M Cox

  77. recA protein of Escherichia coli promotes branch migration, a kinetically distinct phase of DNA strand exchange.

    Article • Proceedings of the National Academy of Sciences, June 1981, Proceedings of the National Academy of Sciences

    Dr Michael M Cox

  78. The Bacterial RecA Protein: Structure, Function, and Regulation

    Article • Springer Science + Business Media

    Dr Michael M Cox

  79. RecA Protein

    Article • Springer Science + Business Media

    Dr Michael M Cox