All Stories

  1. Characterization of Lactococcus lactis subspecies lactis strain Y-PDH01-07 isolated from traditional Indonesian fermented milk ( dadih ) as an oral probiotic c...
  2. Doxorubicin-induced nephrotoxicity: the protective role of a standardized ethanolic extract of Andrographis paniculata leaves
  3. Unveiling predisposing factors for cefepime‐induced neurotoxicity: A systematic review and meta‐analysis
  4. Survivin knockout attenuates the progressiveness of BT549 triple negative-breast cancer cells: an in vitro study highlighting stemness and cellular stress response mechanisms
  5. Development and Characterization of Curcumin Nanosuspension Formulation for Pulmonary Drug Delivery
  6. Development of transethosomes patch for delivery atorvastatin calcium transdermally: In vitro and in vivo studies
  7. Efficacy of N-acetylcysteine and motivational enhancement therapy for nicotine addiction: A randomized clinical trial
  8. Moringa oleifera Leaf Extract Improves Cognitive Function in Rat Offspring Born to Protein-Deficient Mothers
  9. ADDITIVE CYTOTOXIC EFFECT OF CISPLATIN AND ANDROGRAPHIS PANICULATA EXTRACT THROUGH THE MODULATION OF APOPTOTIC MARKERS, CYCLIN-D AND VEGF EXPRESSIONS IN SKOV3 OVARIAN CANCER CELL LINE
  10. <b>Clinical and histopathological evaluation of 5-fluorouracil-induced oral mucositis in a rat model</b>
  11. Misuse of Mixed Prescribed Medication (Obat Rombongan) as Self-Medication: Lesson Learned from Gedong Pompa Urban Kampung, Jakarta, Indonesia
  12. Dual sgRNA-directed knock out survivin gene expression using CRISPR/Cas9 technology for editing survivin gene in triple-negative breast cancer
  13. The Role of FLT3-ITD Mutation, PI3K/AKT Pathway, and Leukemia Stem Cells in D3A7 Induction therapy – the Outcomes of Adult Indonesian Patients with Acute Myeloid Leukemia
  14. Peripheral Serum AMH Level Reflects the Size of the Follicle Pool in a Mouse Model Study
  15. Identification of a novel mutation of the FLT3 gene located on the juxtamembrane domain from acute myeloid leukemia patients
  16. Effectivity of oral ginger supplementation for chemotherapy induced nausea and vomiting (CINV) in children: A systematic review of clinical trials
  17. Repurposing effect of cardiovascular-metabolic drug to increase lifespan: a systematic review of animal studies and current clinical trial progress
  18. Evaluating the Acute Toxicity and In vivo Protective Effect of Standardized Andrographis paniculata Extract against Doxorubicin-induced Cardiotoxicity in Sprague-dawley Rats
  19. Andrographis paniculata: A potential supplementary therapy for cardiovascular diseases - A systematic review of its effects and molecular actions
  20. CD44 and CD133 protein expression might serve as a prognostic factor for early occurrence castration‐resistant prostate cancer
  21. Antimalarial Activity of Mangrove Plants and Possible Mechanisms of Action: A Scoping Review
  22. Investigation of Correlation between Resistance to Diazepam and Expression of Inflammatory Markers in The Peripheral Blood of Patients with Status of Epilepticus
  23. Histopathology assay of the lung after intratracheal injection of SARS-CoV-2 spike protein recombinant in mice: A preliminary study
  24. 6-gingerol as an antioxidant to ameliorate kidney injury in high-fat high-fructose diet-induced metabolic syndrome in rats
  25. In vivo toxicity study in Sprague-Dawley rats receiving different doses of Moringa oleifera extract
  26. NUDT15Polymorphism and Its Association With Mercaptopurine Hematotoxicity in Acute Lymphoblastic Leukemia in Indonesian Children
  27. Purification and characterization of a novel zinc chelating peptides from Holothuria scabra and its ex vivo absorption activity in the small intestine
  28. Andrographolide Reverses Doxorubicin Resistance in Human Breast Cancer Stem Cells by Regulating Apoptotic Gene Expressions
  29. STRUCTURAL PREDICTION OF HUMAN ZIP 2 AND ZIP4 BASED ON HOMOLOGY MODELLING AND MOLECULAR SIMULATION
  30. The stent thrombosis in Belgium (STIB) scoring system reliability in Indonesia patients and the modified STIB scoring (M-STIB)
  31. Moringa oleifera Leaves Extract Ameliorates Doxorubicin-Induced Cardiotoxicity via Its Mitochondrial Biogenesis Modulatory Activity in Rats
  32. Vitamin D supplementation alleviates insulin resistance in prediabetic rats by modifying IRS-1 and PPARγ/NF-κB expressions
  33. 6-gingerol ameliorates weight gain and insulin resistance in metabolic syndrome rats by regulating adipocytokines
  34. Multidrug Resistance-1 C3435T Polymorphism and Carbamazepine Plasma Level in Indonesian Temporal Lobe Epilepsy Patients
  35. Nanocurcumin preserves kidney function and haematology parameters in DMBA-induced ovarian cancer treated with cisplatin via its antioxidative and anti-inflammatory effect in rats
  36. Alpha-Mangosteen lessens high-fat/high-glucose diet and low-dose streptozotocin induced-hepatic manifestations in the insulin resistance rat model
  37. Correlation P2Y12 Genetic Polymorphism As Risk Factor of Clopidogrel Resistance in Indonesian Stroke Patients
  38. Acute exacerbation of idiopathic pulmonary fibrosis model in the rats using bleomycin and lipopolysaccharides
  39. Impact of Ultrasonic Assisted Extraction on the Protein Yield from Moringa Oleifera Lam Leaves and its Functional Characterization
  40. PATTERNS OF METHAMPHETAMINE USE AND ITS ASSOCIATIONS WITH PSYCHIATRIC SYMPTOMS IN PATIENTS UPON ADMISSION AT THE NATIONAL REHABILITATION CENTER LIDO BOGOR, INDONESIA
  41. Deciphering Driver of Nasopharyngeal Cancer Development
  42. Azithromycin concentration in rabbits’ plasma and posterior segment of the eyes following oral drug administration: a dose-finding study for the application in ocular toxoplasmosis
  43. Protective effects of silver nanoparticles in isoproterenol-induced myocardial infarction in rats
  44. Lack of Correlation Between Soluble Angiotensin-Converting Enzyme 2 and Inflammatory Markers in Hospitalized COVID-19 Patients with Hypertension
  45. Alpha-mangostin counteracts hyperuricemia and renal dysfunction by inhibiting URAT1 renal transporter in insulin resistance rat model
  46. Alpha-Mangostin Enhances Proliferation in Sorafenib-Surviving HepG2 Liver Cancer Cells by Increasing Anti-Apoptosis and Antioxidant Markers Expressions
  47. Clopidogrel Resistance Among Ischemic Stroke Patients and Its Risk Factors in Indonesia
  48. Association of Somatic Gene Mutations with Risk of Transformation into Acute Myeloid Leukemia in Patients with Myelodysplastic Syndrome: A Systematic Review and Meta-Analysis
  49. Moringa Oleifera Lam. in Cardiometabolic Disorders: A Systematic Review of Recent Studies and Possible Mechanism of Actions
  50. Hematological indices and their correlation with glucose control parameters in a prediabetic rat model
  51. Approach for the study of COVID-19 infection and vaccine development using mice model: A narrative review
  52. Glucose-responsive pectin insulin patch for diabetes mellitus: A review
  53. Attenuation of cisplatin-induced hepatotoxicity by nanocurcumin through modulation of antioxidative and anti-inflammatory pathways
  54. TGF-β-Induced TMEPAI Promotes Epithelial–Mesenchymal Transition in Doxorubicin-Treated Triple-Negative Breast Cancer Cells via SMAD3 and PI3K/AKT Pathway Alteration
  55. Safety and Pharmacokinetic Profiles of Long-Acting Injectable Antiretroviral Drugs for HIV-1 Pre-Exposure Prophylaxis: A Systematic Review and Meta-analysis of Randomized Trials
  56. Efficacy of adjuvant intrastromal and combination of intrastromal and intracameral voriconazole in <em>Aspergillus fumigatus</em>-induced moderate fungal keratitis in rabbits
  57. Does HIV increase the risk of adverse events during the treatment of drug-resistant tuberculosis?
  58. Correction: In silico and in vitro studies on the anti-cancer activity of andrographolide targeting survivin in human breast cancer stem cells
  59. A Mini Systematic Review: Eucheuma cottonii, a Red Algae, as a Radiosensitizer?
  60. FLT3-ITD Mutation and FLT3 Ligand Plasma Level Were Not Associated with One-Year Survival of Indonesian Acute Myeloid Leukemia Patients
  61. TPMT Genetic Variability and Its Association with Hematotoxicity in Indonesian Children with Acute Lymphoblastic Leukemia in Maintenance Therapy
  62. Curcumin Nanoparticle Enhances the Anticancer Effect of Cisplatin by Inhibiting PI3K/AKT and JAK/STAT3 Pathway in Rat Ovarian Carcinoma Induced by DMBA
  63. Caffeine Intake and the Risk of Female Primary Infertility: An Evidence-Based Case Report
  64. The future potential of Annona muricata L. extract and its bioactive compounds as radiation sensitizing agent: proposed mechanisms based on a systematic review
  65. Immunogenicity and Efficacy of Insulin Glargine Biosimilar Ezelin versus Originator Insulin Glargine in Patients with Type 2 Diabetes
  66. Determine curcumin concentration in organ rats and in ovaries at ovarian cancer model rats using ultra performance liquid chromatography-mass spectrometry (MS)/MS
  67. Probiotics in the Management of Atopic Dermatitis for Children: A Case-Based Review
  68. In silico and in vitro studies on the anti-cancer activity of andrographolide targeting survivin in human breast cancer stem cells
  69. Development, Characterization and Pharmacokinetic Profile of Chitosan-Sodium Tripolyphosphate Nanoparticles Based Drug Delivery Systems for Curcumin
  70. Prognostic Significance of Fms-Like Tyrosine Kinase 3 Internal Tandem Duplication Mutation in Non-Transplant Adult Patients with Acute Myeloblastic Leukemia: A Systematic Review and Meta-Analysis
  71. Curcumin Prevents Epithelial-to Mesenchymal Transition-Mediated Ovarian Cancer Progression through NRF2/ETBR/ET-1 Axis and Preserves Mitochondria Biogenesis in Kidney after Cisplatin Administration
  72. Therapeutic response time of topical voriconazole 1% and intrastromal voriconazole 0.05% versus topical natamycin 5% monotherapy in Fusarium keratitis in rabbit
  73. The Effect of Alpha Mangostin on Epithelial-Mesenchymal Transition on Human Hepatocellular Carcinoma HepG2 Cells Surviving Sorafenib via TGF-β/Smad Pathways
  74. Alpha-mangostin reduces cell viability in sorafenib-surviving cells by modulating multiple drug transporters in HepG2 hepatocellular carcinoma cells
  75. Selected Indonesian Medicinal Plants for the Management of Metabolic Syndrome: Molecular Basis and Recent Studies
  76. Mutation Analysis of ABL1 Gene and its Relation to the Achievement of Major Molecular Response in Indonesian Chronic Myeloid Leukemia Patients
  77. <p>Alpha-Mangostin Improves Cardiac Hypertrophy and Fibrosis and Associated Biochemical Parameters in High-Fat/High-Glucose Diet and Low-Dose Streptozotocin Injection-Induced Type 2 Diabetic Rats</p>
  78. <p>TGF-β-Induced TMEPAI Attenuates the Response of Triple-Negative Breast Cancer Cells to Doxorubicin and Paclitaxel</p>
  79. Association of CYP2D6*10 (c. 100 C>T) Genotype with Z-END Concentration in Patients with Breast Cancer Receiving Tamoxifen Therapy in Indonesian Population
  80. Association between C1236T Genetic Variant of ABCB1 Gene and Molecular Response to Imatinib in Indonesian Chronic Myeloid Patients
  81. A glance at molecular mechanisms underlying cisplatin-induced nephrotoxicity and possible renoprotective strategies: a narrative review
  82. Decreased sensitivity of several anticancer drugs in TMEPAI knockout triple-negative breast cancer cells
  83. Vitamin D as an Adjunctive Treatment to Standard Drugs in Pulmonary Tuberculosis Patients: An Evidence-Based Case Report
  84. QUERCETIN IMPROVES THE EFFICACY OF SORAFENIB IN TRIPLE NEGATIVE BREAST CANCER CELLS THROUGH THE MODULATION OF DRUG EFFLUX TRANSPORTERS EXPRESSIONS
  85. CURCUMIN INCREASES THE SENSITIVITY OF BREAST CANCER CELLS TO TAMOXIFEN BY INHIBITING MRP2 MRNA EXPRESSION OF EFFLUX TRANSPORTER MRP2
  86. SENSITIVITY OF BREAST CANCER STEM CELLS (CD24-/CD44+) TO DOXORUBICIN IS ASSOCIATED WITH OXIDATIVE STRESS STATUS
  87. HEPATOPROTECTIVE EFFECTS OF L-CITRULLINE AGAINST DOXORUBICIN-INDUCED LIVER DAMAGE IN RATS: AN ANALYSIS OF SERUM BIOMARKERS
  88. ANTIOXIDATIVE ACTIVITY OF ALPHA-MANGOSTIN IN ACETALDEHYDE-INDUCED HEPATIC STELLATE CELLS: AN IN VITRO STUDY
  89. THE EFFECT OF CURCUMIN ON THE PROLIFERATION AND EXTRACELLULAR MATRIX PRODUCTION IN ETHANOL-INDUCED HEPATIC STELLATE CELLS
  90. Pharmacokinetic Profile of Curcumin and Nanocurcumin in Plasma, Ovary, and Other Tissues
  91. Apoptotic activity of alpha-mangostin in acetaldehyde- induced LX2 hepatic stellate cell lines
  92. Intrahepatic transport of primaquine with OCT1: An in vitro study in HepG2 cells
  93. Efficient validated method of UPLC-MS/MS to determine curcumin in rat plasma and ovarium
  94. Comparative effect of curcumin and nanocurcumin on nephroprotection at cisplatin-induced rats
  95. Effective and safe pharmacotherapy for pediatric population: a call for academia to conduct clinical research
  96. EFFECT OF NANOCURCUMIN ON CISPLATIN-INDUCED ACUTE KIDNEY INJURY: A FOCUS ON NRF2 AND KEAP1
  97. EFFECTS OF CURCUMIN AND NANOCURCUMIN ON CISPLATIN-INDUCED NEPHROTOXICITY IN RAT: COPPER TRANSPORTER 1 AND ORGANIC CATION TRANSPORTER 2 AS DRUG TRANSPORTERS
  98. PIPERINE IN THE PREVENTION OF THE DECREASED TAMOXIFEN SENSITIVITY IN MCF-7 BREAST CANCER CELL LINE
  99. THE MODULATION OF DRUG EFFLUX TRANSPORTER BY CURCUMIN IN MCF7 BREAST CANCER CELLS AFTER REPEATED EXPOSURE OF ENDOXIFEN AND ESTRADIOL
  100. Protective Effect ofPhaleria macrocarpaWater Extract (Proliverenol) against Carbon Tetrachloride-Induced Liver Fibrosis in Rats: Role of TNF-αand TGF-β1
  101. Alpha Mangostin Inhibits the Proliferation and Activation of Acetaldehyde Induced Hepatic Stellate Cells through TGF-β and ERK 1/2 Pathways
  102. Association of Impaired Cytochrome P450 2D6 Activity Genotype and Phenotype With Therapeutic Efficacy of Primaquine Treatment for LatentPlasmodium vivaxMalaria
  103. Silymarin increases the sensitivity of breast cancer cells to doxorubicin in doxorubicin-induced MCF-7 cells by inhibiting breast cancer resistance protein expression
  104. Pre-Treatment with Curcumin Ameliorates Cisplatin-Induced Kidney Damage by Suppressing Kidney Inflammation and Apoptosis in Rats
  105. The preventive effect of<em> Mangifera foetida</em> L. leaf extract administered simultaneously to excess iron on markers of iron overload in Spraque-Dawley rats
  106. Knock-out transmembrane prostate androgen-induced protein gene suppressed triple-negative breast cancer cell proliferation
  107. The effects of quercetin on oxidative stress and fibrosis markers in chronic kidney disease rat model
  108. Alpha mangostin Inhibits Hepatic Stellate Cells Activation Through TGF-β/Smad and Akt Signaling Pathways: An in vitro Study in LX2
  109. Characterization and Antiproliferative Activity of Fucoidan from Turbinaria decurren on Ethanol-Induced Hepatic Stellate Cells
  110. Curcumin Increases Anti-Cancer Activity of Tamoxifen in MCF-7 Breast Cancer Cells Through the Suppression of MDR1 mRNA Expression
  111. Effects of Nanocurcumin Against Cisplatin Induced-Nephrotoxicity in Rats
  112. Nano-Curcumin Inhibits Hepatic Stellate Cells Proliferations Induced by Alcohol by Inhibiting TGF-β
  113. Phaseolus vulgaris Extract Reduced Glucose Absorption After Rice Intake: A Study in Indonesian Healthy Volunteers
  114. TMEPAI genome editing in triple negative breast cancer cells
  115. Positive Correlation Between Kidney Injury Molecule-1 and Gentamicin Trough Level in Neonates with Infection
  116. Increased vimentin mRNA expression in MCF-7 breast cancer cell line after repeated endoxifen-treatment
  117. Anti-Hepatitis C Virus Activity of a Crude Extract from Longan (<i>Dimocarpus longan</i> Lour.) Leaves
  118. Drug Efflux Transporters Are Overexpressed in Short-Term Tamoxifen-Induced MCF7 Breast Cancer Cells
  119. Cardioprotection mechanism of mangiferin on doxorubicin-induced rats: Focus on intracellular calcium regulation
  120. Confirmed Plasmodium vivax Resistance to Chloroquine in Central Vietnam
  121. in vitro Modulation of P-glycoprotein, MRP-1 and BCRP Expression by Mangiferin in Doxorubicin-Treated MCF-7 Cells
  122. New Insight into the Molecular Drug Target of Diabetic Nephropathy
  123. Medicinal plants: source of new lead compounds in therapeutics
  124. Lack of a relationship between the serum concentration of aminoglycosides and ototoxicity in neonates
  125. A closer look at hypoxia inducible factor
  126. Influence of primaquine and ritonavir interaction on CYP3A4 mRNA expression in HepG2 cell culture
  127. The efficacy of nebulized procaterol versus nebulized salbutamol for the treatment of moderate acute asthma: a randomized, double-blind, parallel group study
  128. Primaquine decreased plasma concentration of ritonavir: single- and repeated-dose study in Sprague Dawley rats
  129. Incretin-based therapies for type 2 diabetes mellitus in Asian patients: Analysis of clinical trials
  130. The effect of lycopene on the total cytochrome P450, CYP1A2 and CYP2E1