All Stories

  1. Shedding light on the roles of liver X receptors in cancer by using chemical probes

    Article • British Journal of Pharmacology, August 2020, Wiley

    Maura Marinozzi

  2. Laboratory-Scale Preparative Enantioseparations of Pharmaceutically Relevant Compounds on Commercially Available Chiral Stationary Phases for HPLC

    Article • Current Medicinal Chemistry, April 2017, Bentham Science Publishers

    Professor Benedetto Natalini, Maura Marinozzi

  3. The Systems Biology of Transporters - Targeting the Regulatory System for Transporters (FXR/RXR)

    Article • February 2017, Wiley

    Maura Marinozzi

  4. N-Decyl-S-trityl-(R)-cysteine, a new chiral selector for “green” ligand-exchange chromatography applications

    Article • Journal of Pharmaceutical and Biomedical Analysis, February 2017, Elsevier

    PhD Andrea Carotti, Maura Marinozzi

  5. λ5-Phosphorus-Containing α-Diazo Compounds: A Valuable Tool for Accessing Phosphorus-Functionalized Molecules

    Article • Chemical Reviews, November 2016, American Chemical Society (ACS)

    Maura Marinozzi

  6. The Janus-faced nature of IDO1 in infectious diseases: challenges and therapeutic opportunities

    Article • Future Medicinal Chemistry, January 2016, Future Science

    ANTONIO MACCHIARULO, PhD Andrea Carotti, Maura Marinozzi

  7. Antioxidant activity of phenolic extracts from different cultivars of Italian onion (Allium cepa) and relative human immune cell proliferative induction

    Article • Pharmaceutical Biology, October 2015, Informa Healthcare

    Maura Marinozzi

  8. Diastereo- and enantioseparation of a Nα-Boc amino acid with a zwitterionic quinine-based stationary phase: Focus on the stereorecognition mechanism

    Article • Analytica Chimica Acta, July 2015, Elsevier

    PhD Andrea Carotti, Maura Marinozzi

  9. S-Trityl-(R)-Cysteine, a Multipurpose Chiral Selector for Ligand-Exchange Liquid Chromatography Applications

    Article • Critical Reviews in Analytical Chemistry, May 2015, Taylor & Francis

    Maura Marinozzi

  10. ChemInform Abstract: Microwave-Assisted Cycloaddition of Diisopropyl Diazomethylphosphonate to Electron-Deficient Alkenes: Synthesis of Multifunctionalized Phosphonopyrazolines and Phosphonopyrazoles.

    Article • ChemInform, April 2015, Wiley

    Maura Marinozzi

  11. N-Aryl-5-aminopyrazole: A Versatile Architecture in Medicinal Chemistry

    Article • Mini-Reviews in Medicinal Chemistry, March 2015, Bentham Science Publishers

    Maura Marinozzi, PhD Andrea Carotti

  12. Microwave-assisted cycloaddition of diisopropyl diazomethylphosphonate to electron-deficient alkenes: synthesis of multifunctionalized phosphonopyrazolynes and phosphonopyrazoles

    Article • Tetrahedron, December 2014, Elsevier

    Maura Marinozzi

  13. Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands

    Article • Current Topics in Medicinal Chemistry, November 2014, Bentham Science Publishers

    ANTONIO MACCHIARULO, PhD Andrea Carotti, Maura Marinozzi

  14. Editorial: (Thematic Issue: Medicinal Chemistry of Farnesoid X Receptor (FXR) Modulators: The-State-of-the-Art)

    Article • Current Topics in Medicinal Chemistry, November 2014, Bentham Science Publishers

    Maura Marinozzi, Maura Marinozzi

  15. ChemInform Abstract: One-Pot, Telescoped Synthesis of N-Aryl-5-aminopyrazoles from Anilines in Environmentally Benign Conditions.

    Article • ChemInform, September 2014, Wiley

    Maura Marinozzi

  16. One-pot, telescoped synthesis of N-aryl-5-aminopyrazoles from anilines in environmentally benign conditions

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Maura Marinozzi, PhD Andrea Carotti, Maura Marinozzi

  17. Determination of bile salt critical micellization concentration on the road to drug discovery

    Article • Journal of Pharmaceutical and Biomedical Analysis, January 2014, Elsevier

    Maura Marinozzi

  18. Combined monodimensional chromatographic approaches to monitor the presence of d-amino acids in cheese

    Article • Food Control, December 2013, Elsevier

    Maura Marinozzi

  19. The effect of mobile phase composition in the enantioseparation of pharmaceutically relevant compounds with polysaccharide-based stationary phases

    Article • Biomedical Chromatography, August 2013, Wiley

    Maura Marinozzi

  20. Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: Role of the chirality on the biological activity

    Article • Bioorganic & Medicinal Chemistry, July 2013, Elsevier

    PhD Andrea Carotti, Maura Marinozzi

  21. Simultaneous diastereo- and enantioseparation of farnesoid X receptor (FXR) agonists with a quinine carbamate-based chiral stationary phase

    Article • Analytical and Bioanalytical Chemistry, August 2012, Springer Science + Business Media

    Maura Marinozzi

  22. Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists

    Article • Bioorganic & Medicinal Chemistry, June 2012, Elsevier

    ANTONIO MACCHIARULO, PhD Andrea Carotti, Maura Marinozzi

  23. Exploring the Synthetic Versatility of the Lewis Acid Induced Decomposition Reaction of α-Diazo-β-hydroxy Esters. The Case of Ethyl Diazo(3-hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl)acetate

    Article • The Journal of Organic Chemistry, September 2011, American Chemical Society (ACS)

    Maura Marinozzi

  24. ChemInform Abstract: Metabotropic Glutamate Receptors: Structure and New Subtype-Selective Ligands

    Article • ChemInform, May 2010, Wiley

    ANTONIO MACCHIARULO, Maura Marinozzi

  25. ChemInform Abstract: Synthesis and Preliminary Biological Evaluation at the GlycineB Site of (+)- and (-)-3-Oxetanylglycine, Novel Non-proteinogenic Amino Acids.

    Article • ChemInform, May 2010, Wiley

    Maura Marinozzi

  26. ChemInform Abstract: Design, Synthesis and Preliminary Evaluation of Novel 3′-Substituted Carboxycyclopropylglycines (XIV) as Antagonists at Group 2 Metabotropic Glutamate Receptors.

    Article • ChemInform, May 2010, Wiley

    ANTONIO MACCHIARULO, Maura Marinozzi

  27. Chiral ligand-exchange separation and resolution of extremely rigid glutamate analogs: 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids

    Article • Analytical and Bioanalytical Chemistry, May 2010, Springer Science + Business Media

    ANTONIO MACCHIARULO, Maura Marinozzi

  28. ChemInform Abstract: Exploring the Metal-Catalyzed Reactions of Furans with Alkyl α-Diazomethanesulfonate and α-Diazomethanephosphonate: Synthesis of ω-Acyl-Substituted Sulfono- and Phosphonobutadienes.

    Article • ChemInform, December 2009, Wiley

    Maura Marinozzi

  29. Synthesis and chromatographic resolution of conformationally constrained analogues of homotaurine

    Article • Tetrahedron, October 2009, Elsevier

    Maura Marinozzi

  30. Exploring the metal-catalyzed reaction of furans with alkyl α-diazomethanesulfonate and α-diazomethanephosphonate: synthesis of ω-acyl-substituted sulfono- and phosphonobutadienes

    Article • Tetrahedron, August 2009, Elsevier

    Maura Marinozzi

  31. Design, synthesis and biological evaluation of novel bicyclo[1.1.1]pentane-based ω-acidic amino acids as glutamate receptors ligands

    Article • Bioorganic & Medicinal Chemistry, January 2009, Elsevier

    ANTONIO MACCHIARULO, Maura Marinozzi

  32. Sequence Variants in Kynurenine Aminotransferase II (KAT II) Orthologs Determine Different Potencies of the InhibitorS-ESBA

    Article • ChemMedChem, August 2008, Wiley

    ANTONIO MACCHIARULO, PhD Andrea Carotti, Maura Marinozzi

  33. Synthesis, Molecular Modeling Studies, and Preliminary Pharmacological Characterization of All Possible 2-(2‘-Sulfonocyclopropyl)glycine Stereoisomers as Conformationally ConstrainedL-Homocysteic Acid Analogs

    Article • Journal of Medicinal Chemistry, September 2007, American Chemical Society (ACS)

    ANTONIO MACCHIARULO, Maura Marinozzi

  34. Synthesis and biological evaluation of (2S)- and (2R)-2-(3′-phosphonobicyclo[1.1.1]pentyl)glycines as novel group III selective metabotropic glutamate receptor ligands

    Article • Bioorganic & Medicinal Chemistry, June 2006, Elsevier

    Maura Marinozzi

  35. Modulators of the Kynurenine Pathway of Tryptophan Metabolism: Synthesis and Preliminary Biological Evaluation of (S)-4-(Ethylsulfonyl)benzoylalanine, a Potent and Selective Kynurenine Aminotransferase II (KAT II) Inhibitor

    Article • ChemMedChem, May 2006, Wiley

    Maura Marinozzi

  36. Cover Picture: Modulators of the Kynurenine Pathway of Tryptophan Metabolism: Synthesis and Preliminary Biological Evaluation of (S)-4-(Ethylsulfonyl)benzoylalanine, a Potent and Selective Kynurenine Aminotransferase II (KAT II) Inhibitor (ChemMedChem ...

    Article • ChemMedChem, May 2006, Wiley

    Maura Marinozzi

  37. Synthesis and Preliminary Biological Evaluation of (2S,1′R,2′S)- and (2S,1′S,2′R)-2-(2′-Phosphonocyclopropyl)glycines, Two Novel Conformationally Constrained L-AP4 Analogues.

    Article • ChemInform, April 2006, Wiley

    Maura Marinozzi

  38. Synthesis and Preliminary Biological Evaluation of 2′-Substituted 2-(3′-Carboxybicyclo[1.1.1]pentyl)glycine Derivatives as Group I Selective Metabotropic Glutamate Receptor Ligands

    Article • ChemMedChem, March 2006, Wiley

    ANTONIO MACCHIARULO, Maura Marinozzi

  39. Synthesis and preliminary biological evaluation of (2S,1′R,2′S)- and (2S,1′S,2′R)-2-(2′-phosphonocyclopropyl)glycines, two novel conformationally constrained l-AP4 analogues

    Article • Bioorganic & Medicinal Chemistry Letters, January 2006, Elsevier

    Maura Marinozzi

  40. Conformationally constrained amino acids: enantiodivergent synthesis of all four stereoisomers of 2-(tetrahydrofuran-2-yl)glycine

    Article • Tetrahedron, January 2005, Elsevier

    Maura Marinozzi

  41. Synthesis of Novel Unsymmetrically Bridgehead-Substituted Phenylselenobicyclo[1.1.1]pentanes.

    Article • ChemInform, September 2004, Wiley

    Maura Marinozzi

  42. Evaluation of the enantiomeric selectivity in the chiral ligand-exchange chromatography of amino acids by a computational model

    Article • Journal of Chromatography A, April 2004, Elsevier

    ANTONIO MACCHIARULO, Maura Marinozzi

  43. Stereoselective synthesis and preliminary evaluation of (+)- and (–)-3-methyl-5-carboxy-thien-2-yl-glycine (3-MATIDA): identification of (+)-3-MATIDA as a novel mGluR1 competitive antagonist

    Article • Il Farmaco, February 2004, Elsevier

    Maura Marinozzi

  44. Towards New Neuroprotective Agents: Design and Synthesis of 4H-Thieno[2,3-c]isoquinolin-5-one Derivatives as Potent PARP-1 Inhibitors.

    Article • ChemInform, January 2004, Wiley

    ANTONIO MACCHIARULO, Maura Marinozzi

  45. Preparative resolution of 1-aminoindan-1,5-dicarboxylic acid (AIDA) by chiral ligand-exchange chromatography

    Article • Chirality, January 2004, Wiley

    Maura Marinozzi

  46. Synthesis of Novel Unsymmetrically Bridgehead-substituted Phenylseleno­bicyclo[1.1.1]pentanes

    Article • Synlett, January 2004, Thieme Publishing Group

    Maura Marinozzi

  47. Towards new neuroprotective agents: design and synthesis of 4H-thieno[2,3-c] isoquinolin-5-one derivatives as potent PARP-1 inhibitors

    Article • Il Farmaco, September 2003, Elsevier

    ANTONIO MACCHIARULO, Maura Marinozzi

  48. Thermal and Catalytic Reaction of Diazoacetylmetallocenes with [60]Fullerene.

    Article • ChemInform, July 2003, Wiley

    Maura Marinozzi

  49. Heterocycles as Companions on Route to Drug Discovery

    Article • ChemInform, June 2003, Wiley

    Maura Marinozzi

  50. Thermal and Catalytic Reactions of Diazoacetylmetallocenes with [60]Fullerene

    Article • Synthetic Communications, January 2003, Taylor & Francis

    Maura Marinozzi

  51. Spiro[2.2]pentane as a Dissymmetric Scaffold for Conformationally Constrained Analogues of Glutamic Acid:  Focus on Racemic 1-Aminospiro[2.2]pentyl-1,4-dicarboxylic Acids

    Article • The Journal of Organic Chemistry, August 2002, American Chemical Society (ACS)

    ANTONIO MACCHIARULO, Maura Marinozzi

  52. Design, synthesis and preliminary evaluation of novel 3′-Substituted carboxycyclopropylglycines as antagonists at group 2 metabotropic glutamate receptors

    Article • Bioorganic & Medicinal Chemistry Letters, December 2001, Elsevier

    ANTONIO MACCHIARULO, Maura Marinozzi

  53. Synthesis and preliminary biological evaluation at the glycineB site of (+)- and (−)-3-oxetanylglycine, novel non-proteinogenic amino acids

    Article • Il Farmaco, August 2001, Elsevier

    Maura Marinozzi

  54. ChemInform Abstract: Synthesis of Methano[60]fullerenephosphonic- and Methano[60]fullerene-diphosphonic Acids.

    Article • ChemInform, March 2001, Wiley

    Maura Marinozzi

  55. Metabotropic glutamate receptors: structure and new subtype-selective ligands

    Article • Il Farmaco, March 2001, Elsevier

    ANTONIO MACCHIARULO, Maura Marinozzi

  56. Synthesis and biological evaluation of 2-(3′-(1 H -tetrazol-5-yl)bicyclo[1.1.1]pent-1-yl)glycine ( S -TBPG), a novel mGlu1 receptor antagonist

    Article • Bioorganic & Medicinal Chemistry, February 2001, Elsevier

    Maura Marinozzi

  57. Novel enantioselective synthesis of (2S,2′R,3′R)-2-(2′,3′-dicarboxycyclopropyl)glycine (DCG-IV)

    Article • Tetrahedron Letters, November 2000, Elsevier

    Maura Marinozzi

  58. ChemInform Abstract: Synthesis, Molecular Modeling and Preliminary Biological Evaluation of 1-Amino-3-phosphono-3-cyclopentene-1-carboxylic Acid and 1-Amino-3-phosphono-2-cyclopentene-1-carboxylic Acid, Two Novel Agonists of Metabotropic Glutamate Recepto

    Article • ChemInform, October 2000, Wiley

    Maura Marinozzi

  59. Modulation of glutamate receptor pathways in the search for new neuroprotective agents

    Article • Il Farmaco, April 1998, Elsevier

    Maura Marinozzi

  60. Dirhodium(II) Tetraacetate-Mediated Decomposition of Ethyldiazoacetate and Ethyldiazomalonate in the Presence of Fullerene. A New Procedure for the Selective Synthesis of [6-6]-Closed Methanofullerenes

    Article • Synlett, October 1997, Thieme Publishing Group

    Maura Marinozzi

  61. Asymmetric synthesis of enantiomerically pure (2S,1′S,2′S,3′R)-phenylcarboxycyclopropylglycine (PCCG-4): a potent and selective ligand at group II metabotropic glutamate receptors

    Article • Bioorganic & Medicinal Chemistry Letters, September 1996, Elsevier

    Maura Marinozzi

  62. (S)-(+)-2-(3‘-Carboxybicyclo[1.1.1]pentyl)- glycine, a Structurally New Group I Metabotropic Glutamate Receptor Antagonist

    Article • Journal of Medicinal Chemistry, January 1996, American Chemical Society (ACS)

    Maura Marinozzi

  63. 1-Aminoindan-1,5-dicarboxylic Acid: A Novel Antagonist at Phospholipase C-Linked Metabotropic Glutamate Receptors

    Article • Journal of Medicinal Chemistry, September 1995, American Chemical Society (ACS)

    Maura Marinozzi

  64. NMDA receptor heterogeneity in mammalian tissues: focus on two agonists, (2S,3R,4S) cyclopropylglutamate and the sulfate ester of 4-hydroxy-(S)-pipecolic acid

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, April 1995, Springer Science + Business Media

    Maura Marinozzi

  65. Synthesis of all four diastereoisomers of 4-(carboxymethyl)proline, a conformationally constrained analogue of 2-aminoadipic acid

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1995, Royal Society of Chemistry

    Maura Marinozzi

  66. Synthesis of 2-azabicyclo[3.1.0]hexane tricarboxylate and its transformation into a new proline-γ-acetic acid equivalent

    Article • Tetrahedron Letters, February 1994, Elsevier

    Maura Marinozzi

  67. Sulfate esters of hydroxy amino acids as stereospecific glutamate receptor agonists

    Article • European Journal of Pharmacology, January 1994, Elsevier

    Maura Marinozzi

  68. Brush-border-enzyme-mediated intestine-specific drug delivery. Amino acid prodrugs of 5-aminosalicylic acid

    Article • Journal of Medicinal Chemistry, December 1993, American Chemical Society (ACS)

    Maura Marinozzi

  69. D-3,4-‘cyclopropylglutamate’ isomers as nmda receptor ligands: Synthesis and enantioselective activity.

    Article • Tetrahedron Letters, January 1990, Elsevier

    Maura Marinozzi

  70. Preparation and physicochemical properties of natural (23R)-3α,7α,23- and (23R)-3α,12α,23-trihydroxylated bile acids and their (23S)-epimers

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1989, Royal Society of Chemistry

    Maura Marinozzi

  71. L-Vinylglycine from L-Homoserine.

    Article • Synthetic Communications, October 1988, Taylor & Francis

    Maura Marinozzi

  72. L-α-Aminoadipic Acid from L-Glutamic Acid

    Article • Synthetic Communications, October 1988, Taylor & Francis

    Maura Marinozzi