All Stories

  1. MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

    Article • Nature, April 2014, Springer Science + Business Media

    Dr Matthieu Desroses, Dr Thomas Lundbäck

  2. ChemInform Abstract: A New Concise Synthesis of 2,3-Dihydroquinazolin-4(1H)-one Derivatives.

    Article • ChemInform, March 2014, Wiley

    Dr Matthieu Desroses

  3. ChemInform Abstract: A Convenient Microwave-Assisted Propylphosphonic Anhydride (T3P®) Mediated One-Pot Pyrazolone Synthesis.

    Article • ChemInform, January 2014, Wiley

    Dr Matthieu Desroses

  4. ChemInform Abstract: A Facile and Efficient Synthesis of Tetrahydro-β-carbolines.

    Article • ChemInform, October 2013, Wiley

    Dr Matthieu Desroses

  5. DXR Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues

    Article • Journal of Medicinal Chemistry, August 2013, American Chemical Society (ACS)

    Dr Matthieu Desroses, Dr Suresh Surisetti

  6. A Convenient Microwave‐Assisted Propylphosphonic Anhydride (T3P®) Mediated One‐Pot Pyrazolone Synthesis

    Article • European Journal of Organic Chemistry, July 2013, Wiley

    Dr Sabin Llona-Minguez, Dr Matthieu Desroses

  7. A facile and efficient synthesis of tetrahydro-β-carbolines

    Article • Tetrahedron Letters, July 2013, Elsevier

    Dr Sabin Llona-Minguez, Dr Matthieu Desroses

  8. Novel N-phenyl-phenoxyacetamide derivatives as potential EthR inhibitors and ethionamide boosters. Discovery and optimization using High-Throughput Synthesis.

    Article • March 2013, Protein Data Bank, Rutgers University

    Dr Matthieu Desroses

  9. A new concise synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives

    Article • New Journal of Chemistry, January 2013, Royal Society of Chemistry

    Dr Matthieu Desroses

  10. Discovery of Novel N -Phenylphenoxyacetamide Derivatives as EthR Inhibitors and Ethionamide Boosters by Combining High-Throughput Screening and Synthesis

    Article • Journal of Medicinal Chemistry, July 2012, American Chemical Society (ACS)

    Dr Matthieu Desroses

  11. Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors

    Article • Journal of Medicinal Chemistry, January 2012, American Chemical Society (ACS)

    Dr Matthieu Desroses

  12. ChemInform Abstract: A Microwave-Assisted, Propylphosphonic Anhydride (T3P®) Mediated One-Pot Fischer Indole Synthesis.

    Article • ChemInform, November 2011, Wiley

    Dr Matthieu Desroses

  13. A microwave-assisted, propylphosphonic anhydride (T3P®) mediated one-pot Fischer indole synthesis

    Article • Tetrahedron Letters, August 2011, Elsevier

    Dr Matthieu Desroses

  14. Crystal structure of human MTH1 and the 8-oxo-dGMP product complex

    Article • FEBS Letters, July 2011, Wiley

    Dr Matthieu Desroses

  15. Ethionamide Boosters: Synthesis, Biological Activity, and Structure−Activity Relationships of a Series of 1,2,4-Oxadiazole EthR Inhibitors

    Article • Journal of Medicinal Chemistry, April 2011, American Chemical Society (ACS)

    Dr Matthieu Desroses

  16. Exploring Drug Target Flexibility Usingin SituClick Chemistry: Application to a Mycobacterial Transcriptional Regulator

    Article • ACS Chemical Biology, November 2010, American Chemical Society (ACS)

    Dr Matthieu Desroses

  17. Synthetic EthR inhibitors boost antituberculous activity of ethionamide

    Article • Nature Reports Stem Cells, May 2009, Springer Science + Business Media

    Dr Matthieu Desroses

  18. Derivatives of Iressa, a Specific Epidermal Growth Factor Receptor Inhibitor, are Powerful Apoptosis Inducers in PC3 Prostatic Cancer Cells

    Article • ChemMedChem, March 2007, Wiley

    Dr Matthieu Desroses

  19. Synthesis of Unsymmetrical Dialkoxy Quinazolines.

    Article • ChemInform, March 2005, Wiley

    Dr Matthieu Desroses

  20. SYNTHESIS OF UNSYMMETRICAL DIALKOXY QUINAZOLINES

    Article • Organic Preparations and Procedures International, October 2004, Taylor & Francis

    Dr Matthieu Desroses

  21. Synthesis of Sugar-Based Ethenyl Ethers Through a Vinyl Bis-Sulfone Methodology.

    Article • ChemInform, October 2003, Wiley

    Dr Matthieu Desroses

  22. Synthesis of sugar-based ethenyl ethers through a vinyl bis-sulfone methodology

    Article • Tetrahedron, June 2003, Elsevier

    Dr Matthieu Desroses

  23. Sugar-based ethenyl ethers: stereoselective dipolar cycloadditions of nitrile oxides

    Article • Tetrahedron Asymmetry, November 2002, Elsevier

    Dr Matthieu Desroses