Professor Matthias Bureik

Identification of new probe substrates for human CYP20A1

• Biological Chemistry
• February 2020

Plasma membrane localization of CYP4Z1 and CYP19A1 and the detection of anti-CYP19A1 au...

• International Immunopharmacology
• August 2019

Functional characterization and mechanistic modeling of the human cytochrome P450 enzym...

• FEBS Letters
• July 2019

Functional expression and activity screening of all human cytochrome P450 enzymes in fi...

• FEBS Letters
• May 2019

Conversion of chenodeoxycholic acid to cholic acid by human CYP8B1

• Biological Chemistry
• May 2019

A comprehensive overview of common polymorphic variants that cause missense mutations i...

• Biomedicine & Pharmacotherapy
• March 2019

Combined chemical and biotechnological production of 20βOH-NorDHCMT, a long-term metabo...

• Journal of Inorganic Biochemistry
• June 2018

A common polymorphic variant of UGT1A5 displays increased activity due to optimized cof...

• FEBS Letters
• April 2018

Efficient substrate screening and inhibitor testing of human CYP4Z1 using permeabilized...

• Biochemical Pharmacology
• December 2017

Bystander signaling via oxidative metabolism

• OncoTargets and Therapy
• August 2017

CYP4Z1 – A Human Cytochrome P450 Enzyme that Might Hold the Key to Curing Breast Cancer

• Current Pharmaceutical Design
• May 2017

Biomarker Autoantibodies detected in breast cancer patients.

• Cellular and Molecular Immunology
• April 2017

Comparison of cytochrome P450 expression in four different human osteoblast models

• Biological Chemistry
• January 2017

Comparative Proteome Analysis inSchizosaccharomyces pombeIdentifies Metabolic Targets t...

• Molecular & Cellular Proteomics
• July 2016

Selective oxidation of UDP-glucose to UDP-glucuronic acid using permeabilized Schizosac...

• Biotechnology Letters
• November 2015

Overcoming the metabolic burden of protein secretion in Schizosaccharomyces pombe – A q...

• Metabolic Engineering
• January 2014

Coexpression of CPR from Various Origins Enhances Biotransformation Activity of Human C...

• Applied Biochemistry and Biotechnology
• June 2013

Unexpected contribution of cytochrome P450 enzymes CYP11B2 and CYP21, as well as CYP3A4...

• Toxicology Letters
• September 2012

Engineering of Human CYP3A Enzymes by Combination of Activating Polymorphic Variants

• Applied Biochemistry and Biotechnology
• August 2012

Production and NMR analysis of the human ibuprofen metabolite 3-hydroxyibuprofen

• Journal of Biotechnology
• February 2012

S-Glucuronidation of 7-mercapto-4-methylcoumarin by human UDP glycosyltransferases in g...

• Biological Chemistry
• September 2011

Production of Ibuprofen Acyl Glucosides by Human UGT2B7

• Drug Metabolism and Disposition
• August 2011

Biotechnological Production of 20-alpha-Dihydrodydrogesterone at Pilot Scale

• Applied Biochemistry and Biotechnology
• April 2011

Whole-cell biotransformation assay for investigation of the human drug metabolizing enz...

• Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
• January 2011

S-Glucuronidation of 7-mercapto-4-methylcoumarin by human UDP glycosyltransferases in g...

• Biological Chemistry
• January 2011

Convenient Gram-Scale Metabolite Synthesis by Engineered Fission Yeast Strains Expressi...

• Applied Biochemistry and Biotechnology
• October 2010

Human 20α-hydroxysteroid dehydrogenase (AKR1C1)-dependent biotransformation with recomb...

• Journal of Biotechnology
• October 2010

Expression and Secretion of a CB4-1 scFv–GFP Fusion Protein by Fission Yeast

• Applied Biochemistry and Biotechnology
• July 2010

Production of human phase 1 and 2 metabolites by whole-cell biotransformation with reco...

• Bioanalysis
• July 2010

Challenges of steroid biotransformation with human cytochrome P450 monooxygenase CYP21 ...

• Journal of Biotechnology
• April 2010

CYP21-catalyzed production of the long-term urinary metandienone metabolite 17β-hydroxy...

• Biological Chemistry
• January 2010

Glucuronide Production by Whole-Cell Biotransformation Using Genetically Engineered Fis...

• Drug Metabolism and Disposition
• December 2009

Biotechnological synthesis of drug metabolites using human cytochrome P450 isozymes het...

• Bioanalysis
• July 2009

Biotechnological Synthesis of the Designer Drug Metabolite 4'-Hydroxymethyl- -pyrrolidi...

• Journal of Analytical Toxicology
• May 2009

Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid

• Biological Chemistry
• April 2009

Use of fission yeast heterologously expressing human cytochrome P450 2B6 in biotechnolo...

• Forensic Science International
• January 2009

Coexpression of redox partners increases the hydrocortisone (cortisol) production effic...

• Journal of Biotechnology
• February 2008

ROS production by adrenodoxin does not cause apoptosis in fission yeast

• APOPTOSIS
• September 2007

Biotechnological synthesis of drug metabolites using human cytochrome P450 2D6 heterolo...

• Biochemical Pharmacology
• August 2007

A fission yeast-based test system for the determination of IC50values of anti-prostate ...

• Journal of Enzyme Inhibition and Medicinal Chemistry
• January 2006

Increased TCA cycle activity and reduced oxygen consumption during cytochrome P450-depe...

• Yeast
• January 2006

A fluorimetric assay for cortisol

• Analytical and Bioanalytical Chemistry
• September 2005

Vitamin D3 Metabolism in Human Glioblastoma Multiforme: Functionality of CYP27B1 Splice...

• Clinical Cancer Research
• August 2005

Efficient conversion of 11-deoxycortisol to cortisol (hydrocortisone) by recombinant fi...

• FEMS Yeast Research
• April 2005

The human mineralocorticoid receptor only partially differentiates between different li...

• FEMS Yeast Research
• April 2005

Phosphorylation of Bovine Adrenodoxin by Protein Kinase CK2 Affects the Interaction wit...

• Biochemistry
• March 2005

Synthesis and Evaluation of Imidazolylmethylenetetrahydronaphthalenes and Imidazolylmet...

• Journal of Medicinal Chemistry
• March 2005

Adrenodoxin (Adx) and CYP11A1 (P450scc) induce apoptosis by the generation of reactive ...

• Biological Chemistry
• January 2005

Inhibition of aldosterone biosynthesis by staurosporine

• Biological Chemistry
• January 2005

The adrenodoxin-like ferredoxin of Schizosaccharomyces pombe mitochondria

• Journal of Inorganic Biochemistry
• July 2004

Development of test systems for the discovery of selective human aldosterone synthase (...

• Molecular and Cellular Endocrinology
• March 2004

The "Bringer" Strategy: A Very Fast and Highly Efficient Method for Construction of Mut...

• Applied Biochemistry and Biotechnology
• January 2004

Production of steroid hormones by fission yeast cells expressing human mitochondrial cy...

• September 2002

Development of a test system for inhibitors of human aldosterone synthase (CYP11B2): sc...

• The Journal of Steroid Biochemistry and Molecular Biology
• June 2002

Functional Expression of Human Mitochondrial CYP11B2 in Fission Yeast and Identificatio...

• Biochemistry
• February 2002

The Human Steroid Hydroxylases CYP11B1 and CYP11B2

• Biological Chemistry
• January 2002

MODULATION OF STEROID HYDROXYLASE ACTIVITY IN STABLY TRANSFECTED V79MZH11B1 AND V79MZH1...

• Endocrine Research
• January 2002

An additional transcript of the cdc25C gene from A431 cells encodes a functional protein.

• International Journal of Oncology
• December 2000

p53 antibodies: Call for quality

• International Journal of Cancer
• November 1997

Human p53 Restores DNA Synthesis Control in Fission Yeast

• Biological Chemistry
• January 1997

Steroid Hydroxylation: Microbial Steroid Biotransformations Using Cytochrome P450 Enzymes