Dr Matthew R Allen
Indiana University School of Medicine
Professor, Medicine And Medical Sciences
United States
My co-authors include
Dr Janet M Hock
Jason Organ
Dr. Lilian I. Plotkin
My Publications
Parathyroid suppression therapy normalizes chronic kidney disease-induced elevations in...
Osteoporosis International
May 2019
Time course of rapid bone loss and cortical porosity formation observed by longitudinal...
Bone
May 2019
Increased FGF23 protects against detrimental cardio-renal consequences during elevated ...
JCI Insight
February 2019
Mechanics of Linear Microcracking in Trabecular Bone
Journal of Biomechanics
November 2018
Reversal of loss of bone mass in old mice treated with mefloquine
Bone
September 2018
Skeletal vascular perfusion is altered in chronic kidney disease
Bone Reports
May 2018
Preclinical Models for Skeletal Research: How Commonly Used Species Mimic (or Don’t) As...
Toxicologic Pathology
September 2017
Effects of combination treatment with alendronate and raloxifene on skeletal properties...
PLoS ONE
August 2017
Improving Combination Osteoporosis Therapy in a Preclinical Model of Heightened Osteoan...
Endocrinology
June 2017
Assessment of regional bone tissue perfusion in rats using fluorescent microspheres
Bone Reports
April 2017
Assessing the inter- and intra-animal variability of in vivo OsteoProbe skeletal measur...
Bone Reports
August 2016
Reference point indentation is insufficient for detecting alterations in traditional me...
Bone
June 2016
Raloxifene reduces skeletal fractures in an animal model of osteogenesis imperfecta
Matrix Biology
May 2016
Influence of Zoledronic Acid on Atrial Electrophysiological Parameters and Electrocardi...
Journal of Cardiovascular Electrophysiology
March 2015
Absence of Exposed Bone Following Dental Extraction in Beagle Dogs Treated With 9 Month...
Journal of Oral and Maxillofacial Surgery
June 2013
Decreased MicroRNA Is Involved in the Vascular Remodeling Abnormalities in Chronic Kidn...
PLoS ONE
May 2013
Bisphosphonate-induced reductions in rat femoral bone energy absorption and toughness a...
Journal of Orthopaedic Research®
March 2013
Reference-point indentation correlates with bone toughness assessed using whole-bone tr...
Bone
March 2013
Microcrack density and nanomechanical properties in the subchondral region of the immat...
Bone
February 2013
Orthodontic mini-implant diameter does not affect in-situ linear microcrack generation ...
American Journal of Orthodontics and Dentofacial Orthopedics
December 2012
Circulating αKlotho influences phosphate handling by controlling FGF23 production
Journal of Clinical Investigation
November 2012
Aging and Estrogen Status: A Possible Endothelium-Dependent Vascular Coupling Mechanism...
PLoS ONE
November 2012
Skeletal effects of zoledronic acid in an animal model of chronic kidney disease
Osteoporosis International
August 2012
Cell autonomous requirement of connexin 43 for osteocyte survival: Consequences for end...
Journal of Bone and Mineral Research
January 2012
Bisphosphonate Binding Affinity Affects Drug Distribution in Both Intracortical and Tra...
Calcified Tissue International
January 2012
Three years of alendronate treatment does not continue to decrease microstructural stre...
Osteoporosis International
January 2012
Sost downregulation and local Wnt signaling are required for the osteogenic response to...
Bone
January 2012
Dietary Phosphate Restriction Normalizes Biochemical and Skeletal Abnormalities in a Mu...
Endocrinology
December 2011
Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype ...
Proceedings of the National Academy of Sciences
October 2011
Bisphosphonates do not alter the rate of secondary mineralization
Bone
October 2011
Increased strontium uptake in trabecular bone of ovariectomized calcium-deficient rats ...
Journal of Synchrotron Radiation
September 2011
Greater magnitude of turnover suppression occurs earlier after treatment initiation wit...
Bone
July 2011
Bisphosphonate effects on bone turnover, microdamage, and mechanical properties: What w...
Bone
July 2011
PTH receptor signaling in osteocytes governs periosteal bone formation and intracortica...
Journal of Bone and Mineral Research
May 2011
Introduction
Clinical Reviews in Bone and Mineral Metabolism
March 2011
Animal Models of Osteonecrosis
Clinical Reviews in Bone and Mineral Metabolism
March 2011
The effects of bisphosphonates on jaw bone remodeling, tissue properties, and extractio...
Odontology
January 2011
Lack of Correlation Between Duration of Osteonecrosis of the Jaw and Sequestra Tissue M...
Journal of Oral and Maxillofacial Surgery
November 2010
Ovariectomy stimulates and bisphosphonates inhibit intracortical remodeling in the mous...
Orthodontics and Craniofacial Research
October 2010
In vivo effects of zoledronic acid on oral mucosal epithelial cells
Oral Diseases
September 2010
Reply to: Fatigue in bone: A novel phenomenon attributable to bisphosphonate use
Bone
August 2010
One year of alendronate treatment lowers microstructural stresses associated with trabe...
Bone
August 2010
Can deterministic mechanical size effects contribute to fracture and microdamage accumu...
Journal of Theoretical Biology
July 2010
Compromised osseous healing of dental extraction sites in zoledronic acid-treated dogs
Osteoporosis International
May 2010
Increased nitric oxide-mediated vasodilation of bone resistance arteries is associated ...
Bone
March 2010
Heritability of lumbar trabecular bone mechanical properties in baboons
Bone
March 2010
Bisphosphonate treatment modifies canine bone mineral and matrix properties and their h...
Bone
March 2010
Bisphosphonates do not inhibit periosteal bone formation in estrogen deficient animals ...
Bone
January 2010
Cancer treatment dosing regimens of zoledronic acid result in near-complete suppression...
Journal of Bone and Mineral Research
December 2009
Morphological Assessment of Basic Multicellular Unit Resorption Parameters in Dogs Show...
Calcified Tissue International
December 2009
Effects of 1 to 3 years' treatment with alendronate on mechanical properties of the fem...
Journal of Orthopaedic Research®
October 2009
Studying the role of microcracks in the pathophysiology of BRONJ
Clinical Oral Investigations
August 2009
Mandibular necrosis in beagle dogs treated with bisphosphonates
Orthodontics and Craniofacial Research
August 2009
Higher Bone Matrix Density Exists in Only a Subset of Patients With Bisphosphonate-Rela...
Journal of Oral and Maxillofacial Surgery
July 2009
Theoretical analysis of alendronate and risedronate effects on canine vertebral remodel...
Journal of Biomechanics
May 2009
The Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaw: So Many Hypotheses...
Journal of Oral and Maxillofacial Surgery
May 2009
Effects of suppression of bone turnover on cortical and trabecular load sharing in the ...
Journal of Biomechanics
March 2009
Corrigendum to “Failure of mineralized collagen fibrils: Modeling the role of collagen ...
Journal of Biomechanics
February 2009
Skeletal changes associated with the onset of type 2 diabetes in the ZDF and ZDSD roden...
AJP Endocrinology and Metabolism
January 2009
Methodological assessment of acid-etching for visualizing the osteocyte lacunar-canalic...
Microscopy Research and Technique
January 2009
Skeletal accumulation of bisphosphonates: implications for osteoporosis treatment
Expert Opinion on Drug Metabolism & Toxicology
October 2008
Changes in non-enzymatic glycation and its association with altered mechanical properti...
Osteoporosis International
October 2008
Identification of material parameters based on Mohr–Coulomb failure criterion for bisph...
Bone
October 2008
Calculating clinically relevant drug doses to use in animal studies
Osteoporosis International
September 2008
Alendronate treatment results in similar levels of trabecular bone remodeling in the fe...
Osteoporosis International
August 2008
Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes
PLoS ONE
August 2008
Bisphosphonates and Osteonecrosis of the Jaw: Moving from the Bedside to the Bench
Cells Tissues Organs
August 2008
Surface-specific Bone Formation Effects of Osteoporosis Pharmacological Treatments
Clinical Reviews in Bone and Mineral Metabolism
June 2008
Skeletal Microdamage: Less About Biomechanics and More About Remodeling
Clinical Reviews in Bone and Mineral Metabolism
May 2008
Mandible Matrix Necrosis in Beagle Dogs After 3 Years of Daily Oral Bisphosphonate Trea...
Journal of Oral and Maxillofacial Surgery
May 2008
Alendronate Reduces Bone Toughness of Ribs without Significantly Increasing Microdamage...
Calcified Tissue International
May 2008
Strontium ranelate does not stimulate bone formation in ovariectomized rats
Osteoporosis International
April 2008
Low Bone Turnover and Microdamage? How and Where to Assess It?
Journal of Bone and Mineral Research
March 2008
Food restriction and simulated microgravity: effects on bone and serum leptin
Journal of Applied Physiology
February 2008
In situ examination of the time-course for secondary mineralization of Haversian bone u...
Matrix Biology
January 2008
Failure of mineralized collagen fibrils: Modeling the role of collagen cross-linking
Journal of Biomechanics
January 2008
Bisphosphonates alter trabecular bone collagen cross-linking and isomerization in beagl...
Osteoporosis International
December 2007
Mechanical Stimulation of Bone in Vivo Reduces Osteocyte Expression of Sost/Sclerostin
Journal of Biological Chemistry
December 2007
Changes in vertebral strength-density and energy absorption-density relationships follo...
Osteoporosis International
August 2007
Raloxifene Enhances Material-Level Mechanical Properties of Femoral Cortical and Trabec...
Endocrinology
August 2007
Three Years of Alendronate Treatment Results in Similar Levels of Vertebral Microdamage...
Journal of Bone and Mineral Research
July 2007
Aging Reduces Skeletal Blood Flow, Endothelium-Dependent Vasodilation, and NO Bioavaila...
Journal of Bone and Mineral Research
April 2007
Exercise-induced changes in the cortical bone of growing mice are bone- and gender-spec...
Bone
April 2007
Nanometer resolution hard X-ray microscopy of bone and mineralized tissue
March 2007
A computational assessment of the independent contribution of changes in canine trabecu...
Journal of Biomechanics
January 2007
Raloxifene enhances vertebral mechanical properties independent of bone density
Bone
November 2006
Antiremodeling Agents Influence Osteoblast Activity Differently in Modeling and Remodel...
Calcified Tissue International
October 2006
Alterations in canine vertebral bone turnover, microdamage accumulation, and biomechani...
Bone
October 2006
The mechanical phenotype of biglycan-deficient mice is bone- and gender-specific
Bone
July 2006
Parathyroid Hormone and Bone Biomechanics
Clinical Reviews in Bone and Mineral Metabolism
January 2006
Defective osteogenesis of the stromal stem cells predisposes CD18-null mice to osteopor...
Proceedings of the National Academy of Sciences
September 2005
Human femoral neck has less cellular periosteum, and more mineralized periosteum, than ...
Bone
February 2005
Effects of eccentric exercise training on cortical bone and muscle strength in the estr...
Journal of Applied Physiology
January 2005
A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem c...
Journal of Clinical Investigation
December 2004
Periosteum: biology, regulation, and response to osteoporosis therapies
Bone
November 2004
Functional recovery of the plantarflexor muscle group after hindlimb unloading in the rat
European Journal of Applied Physiology
July 2004
Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet...
Bone
July 2004
Biglycan Deficiency Interferes With Ovariectomy-Induced Bone Loss
Journal of Bone and Mineral Research
December 2003
Biglycan-Deficient Mice Have Delayed Osteogenesis after Marrow Ablation
Calcified Tissue International
May 2003
Site- and compartment-specific changes in bone with hindlimb unloading in mature adult ...
Bone
July 2002