All Stories

  1. Engineering Escherichia coli Co-Cultures for Production of Curcuminoids From Glucose

    Article • Biotechnology Journal, December 2017, Wiley

    Professor Mattheos Koffas, Professor Jingwen Zhou

  2. Cloning and Expression of Recombinant Chondroitinase ACII and Its Comparison to the Arthrobacter aurescens Enzyme

    Article • Biotechnology Journal, September 2017, Wiley

    Professor Mattheos Koffas, Jordanne Gizzarelli, Dr. Asher Williams

  3. Complete Biosynthesis of Anthocyanins Using E. coli Polycultures

    Article • mBio, June 2017, ASM Journals

    Professor Mattheos Koffas

  4. Naringenin-responsive riboswitch-based fluorescent biosensor module for Escherichia coli co-cultures

    Article • Biotechnology and Bioengineering, June 2017, Wiley

    Professor Mattheos Koffas

  5. Draft Genome Sequence ofBacillus subtilisIa1a, a New Strain for Poly-γ-Glutamic Acid and Exopolysaccharide Production

    Article • Genome Announcements, December 2016, ASM Journals

    Professor Mattheos Koffas

  6. Engineered heparins as new anticoagulant drugs

    Article • Bioengineering & Translational Medicine, November 2016, Wiley

    Professor Mattheos Koffas

  7. Optimization of naringenin andp-coumaric acid hydroxylation using the nativeE. colihydroxylase complex, HpaBC

    Article • Biotechnology Progress, November 2015, Wiley

    Professor Mattheos Koffas

  8. CRISPathBrick: Modular Combinatorial Assembly of Type II-A CRISPR Arrays for dCas9-Mediated Multiplex Transcriptional Repression in E. coli

    Article • ACS Synthetic Biology, September 2015, American Chemical Society (ACS)

    Professor Mattheos Koffas

  9. Development of a Recombinant Escherichia coli Strain for Overproduction of the Plant Pigment Anthocyanin

    Article • Applied and Environmental Microbiology, July 2015, ASM Journals

    Professor Mattheos Koffas

  10. Metabolic pathway balancing and its role in the production of biofuels and chemicals

    Article • Current Opinion in Biotechnology, June 2015, Elsevier

    Professor Mattheos Koffas

  11. Improvement of catechin production in Escherichia coli through combinatorial metabolic engineering

    Article • Metabolic Engineering, March 2015, Elsevier

    Professor Mattheos Koffas

  12. When plants produce not enough or at all: metabolic engineering of flavonoids in microbial hosts

    Article • Frontiers in Plant Science, January 2015, Frontiers

    Professor Mattheos Koffas

  13. Production of chondroitin in metabolically engineered E. coli

    Article • Metabolic Engineering, January 2015, Elsevier

    Professor Mattheos Koffas

  14. Enzymatic formation of a resorcylic acid by creating a structure-guided single-point mutation in stilbene synthase

    Article • Protein Science, December 2014, Wiley

    Professor Mattheos Koffas

  15. Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue molecules

    Article • FEMS Microbiology Reviews, July 2014, Oxford University Press (OUP)

    Mr Brady Fletcher Cress, Professor Mattheos Koffas

  16. A novel cleaning process for industrial production of xylose in pilot scale from corncob by using screw-steam-explosive extruder

    Article • Bioprocess and Biosystems Engineering, June 2014, Springer Science + Business Media

    Professor Mattheos Koffas

  17. Editorial overview: Food biotechnology

    Article • Current Opinion in Biotechnology, April 2014, Elsevier

    Professor Mattheos Koffas, Dr Saurabh Mehta

  18. Design and Kinetic Analysis of a Hybrid Promoter–Regulator System for Malonyl-CoA Sensing in Escherichia coli

    Article • ACS Chemical Biology, February 2014, American Chemical Society (ACS)

    Professor Mattheos Koffas

  19. Biochemical strategies for enhancing the in vivo production of natural products with pharmaceutical potential

    Article • Current Opinion in Biotechnology, February 2014, Elsevier

    Professor Mattheos Koffas

  20. Using Recombinant Microorganisms for the Synthesis and Modification of Flavonoids and Stilbenes

    Article • January 2014, Elsevier

    Mr Brady Fletcher Cress, Professor Mattheos Koffas

  21. Pathway and protein engineering approaches to produce novel and commodity small molecules

    Article • Current Opinion in Biotechnology, December 2013, Elsevier

    Professor Mattheos Koffas

  22. Redirecting carbon flux into malonyl-CoA to improve resveratrol titers: Proof of concept for genetic interventions predicted by OptForce computational framework

    Article • Chemical Engineering Science, November 2013, Elsevier

    Professor Mattheos Koffas

  23. Metabolic engineering and in vitro biosynthesis of phytochemicals and non-natural analogues

    Article • Plant Science, September 2013, Elsevier

    Professor Mattheos Koffas

  24. Expression of Low Endotoxin 3-O-Sulfotransferase in Bacillus subtilis and Bacillus megaterium

    Article • Applied Biochemistry and Biotechnology, August 2013, Springer Science + Business Media

    Professor Mattheos Koffas

  25. Engineering plant metabolism into microbes: from systems biology to synthetic biology

    Article • Current Opinion in Biotechnology, April 2013, Elsevier

    Professor Mattheos Koffas

  26. Draft Genome Sequence of Escherichia coli Strain ATCC 23502 (Serovar O5:K4:H4)

    Article • Genome Announcements, February 2013, ASM Journals

    Mr Brady Fletcher Cress, Professor Mattheos Koffas

  27. Draft Genome Sequence of Escherichia coli Strain Nissle 1917 (Serovar O6:K5:H1)

    Article • Genome Announcements, February 2013, ASM Journals

    Mr Brady Fletcher Cress, Professor Mattheos Koffas

  28. Draft Genome Sequence of Pseudoalteromonas luteoviolacea Strain B (ATCC 29581)

    Article • Genome Announcements, February 2013, ASM Journals

    Mr Brady Fletcher Cress, Professor Mattheos Koffas

  29. Draft Genome Sequence of Escherichia coli Strain ATCC 23506 (Serovar O10:K5:H4)

    Article • Genome Announcements, February 2013, ASM Journals

    Mr Brady Fletcher Cress, Professor Mattheos Koffas

  30. Modular optimization of multi-gene pathways for fatty acids production in E. coli

    Article • Nature Communications, January 2013, Springer Science + Business Media

    Professor Mattheos Koffas

  31. Isoflavonoid Production by Genetically Engineered Microorganisms

    Article • January 2013, Springer Science + Business Media

    Mr Brady Fletcher Cress, Professor Mattheos Koffas

  32. Assembly of Multi-gene Pathways and Combinatorial Pathway Libraries Through ePathBrick Vectors

    Article • January 2013, Springer Science + Business Media

    Professor Mattheos Koffas

  33. Microbial production of flavonoids and terpenoids

    Article • January 2013, Elsevier

    Professor Mattheos Koffas

  34. ePathBrick: A Synthetic Biology Platform for Engineering Metabolic Pathways in E. coli

    Article • ACS Synthetic Biology, July 2012, American Chemical Society (ACS)

    Professor Mattheos Koffas

  35. CHAPTER 6. Non-natural Isoflavonoids

    Article • January 2012, Royal Society of Chemistry

    Professor Mattheos Koffas

  36. Development of Non-Natural Flavanones as Antimicrobial Agents

    Article • PLoS ONE, October 2011, PLOS

    Professor Mattheos Koffas

  37. Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA

    Article • Metabolic Engineering, September 2011, Elsevier

    Professor Mattheos Koffas

  38. Optimization of a heterologous pathway for the production of flavonoids from glucose

    Article • Metabolic Engineering, July 2011, Elsevier

    Professor Mattheos Koffas

  39. An integrated computational and experimental study to increase the intra-cellular malonyl-CoA: Application to flavanone synthesis

    Article • April 2011, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Mattheos Koffas

  40. Melanization of flavonoids by fungal and bacterial laccases

    Article • Yeast, November 2010, Wiley

    Professor Mattheos Koffas

  41. Bioavailability and Recent Advances in the Bioactivity of Flavonoid and Stilbene Compounds

    Article • Current Organic Chemistry, October 2010, Bentham Science Publishers

    Professor Mattheos Koffas

  42. Metabolic engineering ofEscherichia colifor biofuel production

    Article • Biofuels, May 2010, Taylor & Francis

    Professor Mattheos Koffas

  43. A Versatile Microbial System for Biosynthesis of Novel Polyphenols with Altered Estrogen Receptor Binding Activity

    Article • Chemistry & Biology, April 2010, Elsevier

    Professor Mattheos Koffas

  44. Improving NADPH availability for natural product biosynthesis in Escherichia coli by metabolic engineering

    Article • Metabolic Engineering, March 2010, Elsevier

    Professor Mattheos Koffas

  45. Natural Products for Type II Diabetes Treatment

    Article • January 2010, Elsevier

    Professor Mattheos Koffas

  46. Biosynthesis of Cellular Building Blocks

    Article • July 2009, Taylor & Francis

    Professor Mattheos Koffas

  47. Microbial Biosynthesis of Fine Chemicals

    Article • July 2009, Taylor & Francis

    Professor Mattheos Koffas

  48. Biosynthesis and biotechnological production of flavanones: current state and perspectives

    Article • Applied Microbiology and Biotechnology, July 2009, Springer Science + Business Media

    Professor Mattheos Koffas

  49. Metabolic engineering for plant natural product biosynthesis in microbes

    Article • Current Opinion in Biotechnology, December 2008, Elsevier

    Professor Mattheos Koffas

  50. High-yield anthocyanin biosynthesis in engineeredEscherichia coli

    Article • Biotechnology and Bioengineering, May 2008, Wiley

    Professor Mattheos Koffas

  51. Strain Improvement of Recombinant Escherichia coli for Efficient Production of Plant Flavonoids

    Article • Molecular Pharmaceutics, April 2008, American Chemical Society (ACS)

    Professor Mattheos Koffas

  52. Flavonoid Biotransformations in Microorganisms

    Article • January 2008, Springer Science + Business Media

    Professor Mattheos Koffas

  53. Characterization of dihydroflavonol 4-reductases for recombinant plant pigment biosynthesis applications

    Article • Biocatalysis and Biotransformation, January 2008, Taylor & Francis

    Professor Mattheos Koffas

  54. Standardized biosynthesis of flavan-3-ols with effects on pancreatic beta-cell insulin secretion

    Article • Applied Microbiology and Biotechnology, October 2007, Springer Science + Business Media

    Professor Mattheos Koffas

  55. Biosynthesis of 5-deoxyflavanones in microorganisms

    Article • Biotechnology Journal, October 2007, Wiley

    Professor Mattheos Koffas

  56. Combinatorial Mutasynthesis of Flavonoid Analogues from Acrylic Acids in Microorganisms

    Article • Organic Letters, May 2007, American Chemical Society (ACS)

    Professor Mattheos Koffas

  57. Metabolic Engineering

    Article • January 2007, Springer Science + Business Media

    Professor Mattheos Koffas

  58. Expression of a soluble flavone synthase allows the biosynthesis of phytoestrogen derivatives in Escherichia coli

    Article • Applied Microbiology and Biotechnology, March 2006, Springer Science + Business Media

    Professor Mattheos Koffas

  59. Biosynthesis of Natural Flavanones in Saccharomyces cerevisiae

    Article • Applied and Environmental Microbiology, September 2005, ASM Journals

    Professor Mattheos Koffas

  60. Strain improvement by metabolic engineering: lysine production as a case study for systems biology

    Article • Current Opinion in Biotechnology, June 2005, Elsevier

    Professor Mattheos Koffas

  61. Evolutionary metabolic engineering

    Article • Metabolic Engineering, January 2005, Elsevier

    Professor Mattheos Koffas

  62. Engineering metabolism and product formation in Corynebacterium glutamicum by coordinated gene overexpression

    Article • Metabolic Engineering, January 2003, Elsevier

    Professor Mattheos Koffas

  63. Metabolic Engineering

    Article • Annual Review of Biomedical Engineering, August 1999, Annual Reviews

    Professor Mattheos Koffas

  64. Trends In Microbial Synthesis of Natural Products and Biofuels

    Article • Wiley

    Professor Mattheos Koffas