All Stories

  1. From stability to dynamics: understanding molecular mechanisms of regulatory T cells through Foxp3 transcriptional dynamics

    Article • Clinical & Experimental Immunology, September 2018, Wiley

    Dr Masahiro Ono

  2. A temporally dynamic Foxp3 autoregulatory transcriptional circuit controls the effector Treg programme

    Article • The EMBO Journal, July 2018, EMBO

    Dr Masahiro Ono

  3. A timer for analyzing temporally dynamic changes in transcription during differentiation in vivo

    Article • The Journal of Cell Biology, June 2018, Rockefeller University Press

    Dr Masahiro Ono

  4. Elucidating the activation mechanisms for bifurcation of regulatory and effector T cell fates by multidimensional single cell analysis

    Article • March 2018, Cold Spring Harbor Laboratory Press

    Dr Masahiro Ono

  5. A temporally dynamic Foxp3 autoregulatory transcriptional circuit controls the effector Treg programme

    Article • January 2018, Cold Spring Harbor Laboratory Press

    Dr Masahiro Ono

  6. A Timer for analyzing temporally dynamic changes in transcription during differentiation in vivo

    Article • November 2017, Cold Spring Harbor Laboratory Press

    Dr Masahiro Ono

  7. FoxP3 partners up

    Article • Nature Immunology, October 2017, Springer Science + Business Media

    Dr Masahiro Ono

  8. Interplay between the skin barrier and immune cells in patients with atopic dermatitis unraveled by means of mathematical modeling

    Article • Journal of Allergy and Clinical Immunology, June 2017, Elsevier

    Dr Masahiro Ono

  9. Sonic Hedgehog regulates thymic epithelial cell differentiation

    Article • Journal of Autoimmunity, April 2016, Elsevier

    Dr Masahiro Ono

  10. Regulatory T Cells in Melanoma Revisited by a Computational Clustering of FOXP3+T Cell Subpopulations

    Article • The Journal of Immunology, February 2016, The American Association of Immunologists

    Dr Masahiro Ono

  11. A genome wide transcriptional model of the complex response to pre-TCR signalling during thymocyte differentiation

    Article • Oncotarget, September 2015, Impact Journals, LLC

    Dr Masahiro Ono

  12. Controversies concerning thymus-derived regulatory T cells: fundamental issues and a new perspective

    Article • Immunology and Cell Biology, July 2015, Wiley

    Dr Masahiro Ono

  13. A Zap70-dependent feedback circuit is essential for efficient selection of CD4 lineage thymocytes

    Article • Immunology and Cell Biology, January 2015, Wiley

    Dr Masahiro Ono

  14. Follicular helper T cell signature in type 1 diabetes

    Article • Journal of Clinical Investigation, December 2014, American Society for Clinical Investigation

    Dr Masahiro Ono

  15. Visualisation of the T cell differentiation programme by Canonical Correspondence Analysis of transcriptomes

    Article • BMC Genomics, January 2014, Springer Science + Business Media

    Dr Masahiro Ono

  16. Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition

    Article • Developmental Biology, August 2013, Elsevier

    Dr Masahiro Ono

  17. CD4+ but not CD8+ T cells revert the impaired emotional behavior of immunocompromised RAG-1-deficient mice

    Article • Translational Psychiatry, July 2013, Nature

    Professor Fulvio D'Acquisto, Dr Masahiro Ono

  18. Skin Disease Modeling from a Mathematical Perspective

    Article • Journal of Investigative Dermatology, June 2013, Elsevier

    Dr Masahiro Ono

  19. Risk factor-dependent dynamics of atopic dermatitis: modelling multi-scale regulation of epithelium homeostasis

    Article • Interface Focus, February 2013, Royal Society Publishing

    Dr Masahiro Ono, Mauricio Barahona

  20. Tissue-Derived Hedgehog Proteins Modulate Th Differentiation and Disease

    Article • The Journal of Immunology, February 2013, The American Association of Immunologists

    Professor Fulvio D'Acquisto, Dr Masahiro Ono

  21. Visualising the Cross-Level Relationships between Pathological and Physiological Processes and Gene Expression: Analyses of Haematological Diseases

    Article • PLoS ONE, January 2013, PLOS

    Dr Masahiro Ono

  22. Differential effects of inhibition of bone morphogenic protein (BMP) signalling on T-cell activation and differentiation

    Article • European Journal of Immunology, December 2011, Wiley

    Dr Masahiro Ono

  23. Ethics should trump science in Fukushima

    Article • BMJ, June 2011, BMJ

    Dr Masahiro Ono

  24. Skin Barrier Homeostasis in Atopic Dermatitis: Feedback Regulation of Kallikrein Activity

    Article • PLoS ONE, May 2011, PLOS

    Dr Masahiro Ono

  25. Perturbations of both nonregulatory and regulatory FOXP3+ T cells in patients with malignant melanoma

    Article • British Journal of Dermatology, April 2011, Wiley

    Dr Masahiro Ono

  26. HTLV-1 bZIP Factor Induces T-Cell Lymphoma and Systemic Inflammation In Vivo

    Article • PLoS Pathogens, February 2011, PLOS

    Dr Masahiro Ono, Professor Masao Matsuoka

  27. Indispensable Role of the Runx1-Cbfβ Transcription Complex for In Vivo-Suppressive Function of FoxP3+ Regulatory T Cells

    Article • Immunity, October 2009, Elsevier

    Dr Masahiro Ono

  28. Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

    Article • Immunity, June 2009, Elsevier

    Dr Masahiro Ono

  29. Regulatory T Cells and Immune Tolerance

    Article • Cell, May 2008, Elsevier

    Dr Masahiro Ono

  30. Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1

    Article • Nature, March 2007, Springer Science + Business Media

    Dr Masahiro Ono

  31. Foxp3+CD25+CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease

    Article • Immunological Reviews, August 2006, Wiley

    Dr Masahiro Ono

  32. Cutaneous alternariosis in an immunocompetent patient: analysis of the internal transcribed spacer region of rDNA and Brm2 of isolated Alternaria alternata

    Article • British Journal of Dermatology, April 2004, Wiley

    Dr Masahiro Ono