All Stories

  1. A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model

    Article • Journal of Pharmacology and Experimental Therapeutics, August 2019, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Mary Paine

  2. Indinavir Increases Midazolam N-Glucuronidation in Humans: Identification of an Alternate CYP3A Inhibitor Using an In Vitro to In Vivo Approach

    Article • Drug Metabolism and Disposition, April 2019, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Mary Paine

  3. Selection and characterization of botanical natural products for research studies: a NaPDI center recommended approach

    Article • Natural Product Reports, January 2019, Royal Society of Chemistry

    Mary Paine

  4. Selection of Priority Natural Products for Evaluation as Potential Precipitants of Natural Product–Drug Interactions: A NaPDI Center Recommended Approach

    Article • Drug Metabolism and Disposition, May 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Mary Paine

  5. Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation

    Article • Drug Metabolism and Disposition, February 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Mary Paine

  6. Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides

    Article • Drug Metabolism and Disposition, August 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Mary Paine

  7. Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product–Drug Interaction

    Article • Drug Metabolism and Disposition, June 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Mary Paine

  8. Inhibition of Human Aldehyde Oxidase Activity by Diet-Derived Constituents: Structural Influence, Enzyme-Ligand Interactions, and Clinical Relevance

    Article • Drug Metabolism and Disposition, October 2014, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Mary Paine