All Stories

  1. Bevacizumab, Irinotecan, or Topotecan Added to Temozolomide for Children With Relapsed and Refractory Neuroblastoma: Results of the ITCC-SIOPEN BEACON-Neuroblastoma Trial

    Article • Journal of Clinical Oncology, April 2024, American Society of Clinical Oncology (ASCO)

    Professor Martin O Leach

  2. Characterisation of paediatric brain tumours by their MRS metabolite profiles

    Article • NMR in Biomedicine, February 2024, Wiley

    Professor Martin O Leach

  3. Development of machine learning support for reading whole body diffusion-weighted MRI (WB-MRI) in myeloma for the detection and quantification of the extent of disease before and after treatment (MALIMAR): protocol for a cross-sectional diagnostic test...

    Article • BMJ Open, October 2022, BMJ

    Professor Martin O Leach

  4. DCE-MRI is more sensitive than IVIM-DWI for assessing anti-angiogenic treatment-induced changes in colorectal liver metastases

    Article • Cancer Imaging, December 2021, Springer Science + Business Media

    Professor Martin O Leach

  5. Early Response to Chemotherapy in Malignant Pleural Mesothelioma Evaluated Using Diffusion-Weighted Magnetic Resonance Imaging: Initial Observations

    Article • JTO Clinical and Research Reports, December 2021, Elsevier

    Professor Martin O Leach

  6. Quantifying MRI T  1 relaxation in flowing blood: implications for arterial input function measurement in DCE-MRI

    Article • British Journal of Radiology, January 2021, Oxford University Press (OUP)

    Professor Martin O Leach

  7. MRI texture feature repeatability and image acquisition factor robustness, a phantom study and in silico study

    Article • European Radiology Experimental, January 2021, Springer Science + Business Media

    Professor Martin O Leach

  8. A novel roadmap connecting the 1H-MRS total choline resonance to all hallmarks of cancer following targeted therapy

    Article • European Radiology Experimental, January 2021, Springer Science + Business Media

    Professor Martin O Leach

  9. Noise-Corrected, Exponentially Weighted, Diffusion-Weighted MRI (niceDWI) Improves Image Signal Uniformity in Whole-Body Imaging of Metastatic Prostate Cancer

    Article • Frontiers in Oncology, May 2020, Frontiers

    Professor Martin O Leach

  10. Monocarboxylate transporter 1 blockade with AZD3965 inhibits lipid biosynthesis and increases tumour immune cell infiltration

    Article • British Journal of Cancer, January 2020, Springer Science + Business Media

    Professor Martin O Leach

  11. Increased inflammatory lipid metabolism and anaplerotic mitochondrial activation follow acquired resistance to vemurafenib in BRAF-mutant melanoma cells

    Article • British Journal of Cancer, December 2019, Springer Science + Business Media

    Professor Martin O Leach

  12. Psychosocial effects of whole-body MRI screening in adult high-risk pathogenicTP53mutation carriers: a case-controlled study (SIGNIFY)

    Article • Journal of Medical Genetics, November 2019, BMJ

    Professor Martin O Leach

  13. Supervised Machine-Learning Enables Segmentation and Evaluation of Heterogeneous Post-treatment Changes in Multi-Parametric MRI of Soft-Tissue Sarcoma

    Article • Frontiers in Oncology, October 2019, Frontiers

    Professor Martin O Leach

  14. De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy

    Article • Autophagy, September 2019, Taylor & Francis

    Gigin Lin, Professor Martin O Leach

  15. Utility of Multi-Parametric Quantitative Magnetic Resonance Imaging for Characterization and Radiotherapy Response Assessment in Soft-Tissue Sarcomas and Correlation With Histopathology

    Article • Frontiers in Oncology, April 2019, Frontiers

    Professor Martin O Leach

  16. Post-radiotherapy apparent diffusion coefficient (ADC) in children and young adults with high-grade gliomas and diffuse intrinsic pontine gliomas

    Article • Pediatric Hematology and Oncology, April 2019, Taylor & Francis

    Professor Martin O Leach

  17. Methodological consensus on clinical proton MRS of the brain: Review and recommendations

    Article • Magnetic Resonance in Medicine, March 2019, Wiley

    Professor Martin O Leach

  18. Synthetic 4D-CT of the thorax for treatment plan adaptation on MR-guided radiotherapy systems

    Article • Physics in Medicine and Biology, March 2019, Institute of Physics Publishing

    Professor Martin O Leach

  19. Circulating Growth and Sex Hormone Levels and Breast Tissue Composition in Young Nulliparous Women

    Article • Cancer Epidemiology Biomarkers & Prevention, December 2018, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  20. Super-resolution T2-weighted 4D MRI for image guided radiotherapy

    Article • Radiotherapy and Oncology, December 2018, Elsevier

    Professor Martin O Leach

  21. Reproducibility of the lung anatomy under active breathing coordinator control: Dosimetric consequences for scanned proton treatments

    Article • Medical Physics, October 2018, Wiley

    Professor Martin O Leach

  22. Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma

    Article • British Journal of Cancer, October 2018, Springer Science + Business Media

    Professor Martin O Leach

  23. Prospective multicentre evaluation and refinement of an analysis tool for magnetic resonance spectroscopy of childhood cerebellar tumours

    Article • Pediatric Radiology, July 2018, Springer Science + Business Media

    Professor Martin O Leach

  24. Evaluating Imaging Biomarkers of Acquired Resistance to Targeted EGFR Therapy in Xenograft Models of Human Head and Neck Squamous Cell Carcinoma

    Article • Frontiers in Oncology, July 2018, Frontiers

    Professor Martin O Leach

  25. Abstract 4108: Longitudinal diffusion-weighted MRI assessment of NRAS mutant melanoma response to dual RAF-MEK inhibition reveals differences associated with collagen deposition

    Article • Cancer Research, July 2018, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  26. PO-0959: Dosimetric Evaluation of Midposition Pseudo-CT for MR-only Lung Radiotherapy Treatment planning

    Article • Radiotherapy and Oncology, April 2018, Elsevier

    Professor Martin O Leach

  27. Microstructure Characterization of Bone Metastases from Prostate Cancer with Diffusion MRI: Preliminary Findings

    Article • Frontiers in Oncology, February 2018, Frontiers

    Professor Martin O Leach

  28. MRI-based Assessment of 3D Intrafractional Motion of Head and Neck Cancer for Radiation Therapy

    Article • International Journal of Radiation Oncology*Biology*Physics, February 2018, Elsevier

    Professor Martin O Leach

  29. Evaluation of the combination of the dual m-TORC1/2 inhibitor vistusertib (AZD2014) and paclitaxel in ovarian cancer models

    Article • Oncotarget, December 2017, Impact Journals, LLC

    Professor Martin O Leach

  30. Non-Invasive Prostate Cancer Characterization with Diffusion-Weighted MRI: Insight from In silico Studies of a Transgenic Mouse Model

    Article • Frontiers in Oncology, December 2017, Frontiers

    Professor Martin O Leach

  31. Quantitative evaluation of contrast agent uptake in standard fat-suppressed dynamic contrast-enhanced MRI examinations of the breast

    Article • Medical Physics, November 2017, Wiley

    Professor Martin O Leach

  32. Changes in multimodality functional imaging parameters early during chemoradiation predict treatment response in patients with locally advanced head and neck cancer

    Article • European Journal of Pediatrics, November 2017, Springer Science + Business Media

    Professor Martin O Leach

  33. Growth Trajectories, Breast Size, and Breast-Tissue Composition in a British Prebirth Cohort of Young Women

    Article • American Journal of Epidemiology, November 2017, Oxford University Press (OUP)

    Professor Martin O Leach

  34. Accuracy of screening women at familial risk of breast cancer without a known gene mutation: Individual patient data meta-analysis

    Article • European Journal of Cancer, November 2017, Elsevier

    Professor Martin O Leach

  35. MCT1 Inhibitor AZD3965 Increases Mitochondrial Metabolism, Facilitating Combination Therapy and Noninvasive Magnetic Resonance Spectroscopy

    Article • Cancer Research, October 2017, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  36. Characterisation of fibrosis in chemically-induced rat mammary carcinomas using multi-modal endogenous contrast MRI on a 1.5T clinical platform

    Article • European Radiology, October 2017, Springer Science + Business Media

    Professor Martin O Leach

  37. T2-Weighted 4D Magnetic Resonance Imaging for Application in Magnetic Resonance–Guided Radiotherapy Treatment Planning

    Article • Investigative Radiology, October 2017, Wolters Kluwer Health

    Professor Martin O Leach

  38. Magnetic Resonance Imaging–Based Assessment of Breast Cancer–Related Lymphoedema Tissue Composition

    Article • Investigative Radiology, September 2017, Wolters Kluwer Health

    Professor Martin O Leach

  39. Detecting human melanoma cell re-differentiation following BRAF or heat shock protein 90 inhibition using photoacoustic and magnetic resonance imaging

    Article • Scientific Reports, August 2017, Springer Science + Business Media

    Professor Martin O Leach

  40. Noninvasive Imaging of Cycling Hypoxia in Head and Neck Cancer Using Intrinsic Susceptibility MRI

    Article • Clinical Cancer Research, August 2017, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  41. Breast MRI segmentation for density estimation: Do different methods give the same results and how much do differences matter?

    Article • Medical Physics, July 2017, Wiley

    Professor Martin O Leach

  42. In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells

    Article • PLoS ONE, July 2017, PLOS

    Professor Martin O Leach

  43. Extracranial Soft-Tissue Tumors: Repeatability of Apparent Diffusion Coefficient Estimates from Diffusion-weighted MR Imaging

    Article • Radiology, July 2017, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  44. Abstract 444: Monocarboxylate transporter 1 inhibition with AZD3965 increases cancer cell dependence on bioenergetic metabolism predicating combination therapy with mitochondrial inhibitors

    Article • Cancer Research, July 2017, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  45. Pediatric and adult glioblastoma radiosensitization induced by PI3K/mTOR inhibition causes early metabolic alterations detected by nuclear magnetic resonance spectroscopy

    Article • Oncotarget, May 2017, Impact Journals, LLC

    Professor Martin O Leach

  46. A generalized framework unifying image registration and respiratory motion models and incorporating image reconstruction, for partial image data or full images

    Article • Physics in Medicine and Biology, May 2017, Institute of Physics Publishing

    Professor Martin O Leach

  47. OC-0303: Evaluation of lung anatomy vs. lung volume reproducibility for scanned proton treatments under ABC.

    Article • Radiotherapy and Oncology, May 2017, Elsevier

    Professor Martin O Leach

  48. Diffusion-weighted Imaging as a Treatment Response Biomarker for Evaluating Bone Metastases in Prostate Cancer: A Pilot Study

    Article • Radiology, April 2017, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  49. Lung volume reproducibility under ABC control and self‐sustained breath‐holding

    Article • Journal of Applied Clinical Medical Physics, February 2017, Wiley

    Professor Martin O Leach

  50. Baseline results from the UK SIGNIFY study: a whole-body MRI screening study in TP53 mutation carriers and matched controls

    Article • Familial Cancer, January 2017, Springer Science + Business Media

    Professor Martin O Leach

  51. P2.05-042 Development of Thoracic Magnetic Resonance Imaging (MRI) for Radiotherapy Planning

    Article • Journal of Thoracic Oncology, January 2017, Elsevier

    Professor Martin O Leach

  52. MRI Applications, Clinical

    Article • January 2017, Elsevier

    Professor Martin O Leach

  53. Magnetic Resonance Spectroscopy to Study Glycolytic Metabolism During Autophagy

    Article • January 2017, Elsevier

    Professor Martin O Leach

  54. Visualizing whole-body treatment response heterogeneity using multi-parametric magnetic resonance imaging

    Article • Journal of Algorithms & Computational Technology, December 2016, SAGE Publications

    Professor Martin O Leach

  55. T 2 -adjusted computed diffusion-weighted imaging: A novel method to enhance tumour visualisation

    Article • Computers in Biology and Medicine, December 2016, Elsevier

    Professor Martin O Leach

  56. The BRAF Inhibitor Vemurafenib Activates Mitochondrial Metabolism and Inhibits Hyperpolarized Pyruvate–Lactate Exchange in BRAF-Mutant Human Melanoma Cells

    Article • Molecular Cancer Therapeutics, December 2016, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  57. Lactate and choline metabolites are potential biomarkers for monitoring response to mTOR pathway inhibitors in combination with the ALK inhibitor crizotinib in ALK-mutated neuroblastoma

    Article • European Journal of Cancer, December 2016, Elsevier

    Professor Martin O Leach

  58. Extended T2-IVIM model for correction of TE dependence of pseudo-diffusion volume fraction in clinical diffusion-weighted magnetic resonance imaging

    Article • Physics in Medicine and Biology, November 2016, Institute of Physics Publishing

    Professor Martin O Leach

  59. Blood transfusion during radical chemo-radiotherapy does not reduce tumour hypoxia in squamous cell cancer of the head and neck

    Article • British Journal of Cancer, November 2016, Springer Science + Business Media

    Professor Martin O Leach

  60. A novel approach to evaluate spatial resolution of MRI clinical images for optimization and standardization of breast screening protocols

    Article • Medical Physics, November 2016, Wiley

    Professor Martin O Leach

  61. Time‐resolved angiography with stochastic trajectories for dynamic contrast‐enhanced MRI in head and neck cancer: Are pharmacokinetic parameters affected?

    Article • Medical Physics, October 2016, Wiley

    Professor Martin O Leach

  62. Pre-natal exposures and breast tissue composition: findings from a British pre-birth cohort of young women and a systematic review

    Article • Breast Cancer Research, October 2016, Springer Science + Business Media

    Professor Martin O Leach

  63. Imaging biomarker roadmap for cancer studies

    Article • Nature Reviews Clinical Oncology, October 2016, Springer Science + Business Media

    Professor Martin O Leach

  64. Modulation of renal oxygenation and perfusion in rat kidney monitored by quantitative diffusion and blood oxygen level dependent magnetic resonance imaging on a clinical 1.5T platform

    Article • BMC Nephrology, October 2016, Springer Science + Business Media

    Professor Martin O Leach

  65. Feasibility and applicability of diffusion-weighted and dynamic contrast-enhanced magnetic resonance imaging in routine assessments of children with high-grade gliomas

    Article • Pediatric Blood & Cancer, September 2016, Wiley

    Professor Martin O Leach

  66. Validating a robust double‐quantum‐filtered 1H MRS lactate measurement method in high‐grade brain tumours

    Article • NMR in Biomedicine, August 2016, Wiley

    Professor Martin O Leach

  67. Slice Encoding for Metal Artefact Correction in magnetic resonance imaging examinations for radiotherapy planning

    Article • Radiotherapy and Oncology, August 2016, Elsevier

    Professor Martin O Leach

  68. Abstract 3973: Diffusion-weighted imaging of bone metastases as treatment response biomarker in prostate cancer

    Article • Cancer Research, July 2016, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  69. BRAF inhibition promotes BRAF mutant human melanoma cell survival under nutrient-deprived conditions through activation of mitochondrial metabolism

    Article • European Journal of Cancer, July 2016, Elsevier

    Professor Martin O Leach

  70. Volume of Bone Metastasis Assessed with Whole-Body Diffusion-weighted Imaging Is Associated with Overall Survival in Metastatic Castration-resistant Prostate Cancer

    Article • Radiology, July 2016, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  71. Development of a temperature‐controlled phantom for magnetic resonance quality assurance of diffusion, dynamic, and relaxometry measurements

    Article • Medical Physics, May 2016, Wiley

    Professor Martin O Leach

  72. Pseudoprogression in children, adolescents and young adults with non-brainstem high grade glioma and diffuse intrinsic pontine glioma

    Article • Journal of Neuro-Oncology, May 2016, Springer Science + Business Media

    Professor Martin O Leach

  73. Inter- and Intra-Observer Repeatability of Quantitative Whole-Body, Diffusion-Weighted Imaging (WBDWI) in Metastatic Bone Disease

    Article • PLoS ONE, April 2016, PLOS

    Professor Martin O Leach

  74. A computerized volumetric segmentation method applicable to multi-centre MRI data to support computer-aided breast tissue analysis, density assessment and lesion localization

    Article • Medical & Biological Engineering & Computing, April 2016, Springer Science + Business Media

    Professor Martin O Leach

  75. Comparison of Dixon Sequences for Estimation of Percent Breast Fibroglandular Tissue

    Article • PLoS ONE, March 2016, PLOS

    Professor Martin O Leach

  76. Repeatability of derived parameters from histograms following non-Gaussian diffusion modelling of diffusion-weighted imaging in a paediatric oncological cohort

    Article • European Radiology, March 2016, Springer Science + Business Media

    Professor Martin O Leach

  77. Contribution of mammography to MRI screening in BRCA mutation carriers by BRCA status and age: individual patient data meta-analysis

    Article • British Journal of Cancer, February 2016, Springer Science + Business Media

    Professor Martin O Leach

  78. Rapid development of image analysis research tools: Bridging the gap between researcher and clinician with pyOsiriX

    Article • Computers in Biology and Medicine, February 2016, Elsevier

    Professor Martin O Leach

  79. Repeatability and sensitivity of measurements in patients with head and neck squamous cell carcinoma at 3T

    Article • Journal of Magnetic Resonance Imaging, January 2016, Wiley

    Professor Martin O Leach

  80. Evaluating the diagnostic sensitivity of computed diffusion-weighted MR imaging in the detection of breast cancer

    Article • Journal of Magnetic Resonance Imaging, January 2016, Wiley

    Professor Martin O Leach

  81. Abstract B56: Treatment-induced autophagy increases amino acid uptake and switches glucose addiction to amino acid catabolism in cancer

    Article • Molecular Cancer Research, January 2016, American Association for Cancer Research (AACR)

    Gigin Lin, Professor Martin O Leach

  82. Abstract B10: Noninvasive pharmacodynamic markers of the dual mTORC1/2 inhibitor AZD2014 in combination with paclitaxel, in cisplatin-resistant ovarian carcinoma xenografts

    Article • Molecular Cancer Research, January 2016, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  83. Response evaluation in mesothelioma: Beyond RECIST

    Article • Lung Cancer, December 2015, Elsevier

    Professor Martin O Leach

  84. Quality assurance in MRI breast screening: comparing signal-to-noise ratio in dynamic contrast-enhanced imaging protocols

    Article • Physics in Medicine and Biology, November 2015, Institute of Physics Publishing

    Professor Martin O Leach

  85. Acting on incidental findings in research imaging

    Article • BMJ, November 2015, BMJ

    Professor Martin O Leach

  86. Characterizing Heterogeneity within Head and Neck Lesions Using Cluster Analysis of Multi-Parametric MRI Data

    Article • PLoS ONE, September 2015, PLOS

    Professor Martin O Leach

  87. Assessment of repeatability and treatment response in early phase clinical trials using DCE-MRI: comparison of parametric analysis using MR- and CT-derived arterial input functions

    Article • European Radiology, September 2015, Springer Science + Business Media

    Professor Martin O Leach

  88. Detecting microvascular changes in the mouse spleen using optical computed tomography

    Article • Microvascular Research, September 2015, Elsevier

    Professor Martin O Leach

  89. Diffusion-weighted MR imaging of metastatic abdominal and pelvic tumours is sensitive to early changes induced by a VEGF inhibitor using alternative diffusion attenuation models

    Article • European Radiology, August 2015, Springer Science + Business Media

    Professor Martin O Leach

  90. Abstract 2897: Phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy

    Article • Cancer Research, August 2015, American Association for Cancer Research (AACR)

    Gigin Lin, Professor Martin O Leach

  91. Abstract 1158: Real-time assessment of uptake and utilization of lactate in intact human breast cancer cells using a 1H-NMR-based assay

    Article • Cancer Research, August 2015, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  92. Abstract CT138: Translating preclinical observations to the clinic: Combination of the dual m-TORC1/2 inhibitor AZD2014 and paclitaxel in ovarian and lung cancer

    Article • Cancer Research, August 2015, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  93. Abstract 1130: Unveiling the metabolic response of BRAF mutant melanoma cells to BRAF inhibition

    Article • Cancer Research, August 2015, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  94. Evaluation of diffusion models in breast cancer

    Article • Medical Physics, July 2015, Wiley

    Professor Martin O Leach

  95. Quantitative Contrast-Enhanced Magnetic Resonance Lymphangiography of the Upper Limbs in Breast Cancer Related Lymphedema: An Exploratory Study

    Article • Lymphatic Research and Biology, June 2015, Mary Ann Liebert Inc

    Professor Martin O Leach

  96. Prospective, longitudinal, multi-modal functional imaging for radical chemo-IMRT treatment of locally advanced head and neck cancer: the INSIGHT study

    Article • Radiation Oncology, May 2015, Springer Science + Business Media

    Professor Martin O Leach

  97. Diffusion-weighted MR neurography for the assessment of brachial plexopathy in oncological practice

    Article • Cancer Imaging, May 2015, Springer Science + Business Media

    Professor Martin O Leach

  98. Phase I Study of Nintedanib Incorporating Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Patients With Advanced Solid Tumors

    Article • The Oncologist, March 2015, Alphamed Press

    Professor Martin O Leach

  99. Multi-centre reproducibility of diffusion MRI parameters for clinical sequences in the brain

    Article • NMR in Biomedicine, March 2015, Wiley

    Professor Martin O Leach

  100. Single-shot single-voxel lactate measurements using FOCI-LASER and a multiple-quantum filter

    Article • NMR in Biomedicine, March 2015, Wiley

    Professor Martin O Leach

  101. Demonstration of the reproducibility of free-breathing diffusion-weighted MRI and dynamic contrast enhanced MRI in children with solid tumours: a pilot study

    Article • European Radiology, March 2015, Springer Science + Business Media

    Professor Martin O Leach

  102. Acquired resistance to EGFR tyrosine kinase inhibitors alters the metabolism of human head and neck squamous carcinoma cells and xenograft tumours

    Article • British Journal of Cancer, March 2015, Springer Science + Business Media

    Professor Martin O Leach

  103. Magnetic Resonance Imaging Improves Breast Screening Sensitivity in BRCA Mutation Carriers Age ≥ 50 Years: Evidence From an Individual Patient Data Meta-Analysis

    Article • Journal of Clinical Oncology, February 2015, American Society of Clinical Oncology (ASCO)

    Professor Martin O Leach

  104. First MRI application of an active breathing coordinator

    Article • Physics in Medicine and Biology, January 2015, Institute of Physics Publishing

    Professor Martin O Leach

  105. Evaluation of lactate detection using selective multiple quantum coherence in phantoms and brain tumours

    Article • NMR in Biomedicine, January 2015, Wiley

    Professor Martin O Leach

  106. High resolution 3D dosimetry for microbeam radiation therapy using optical CT

    Article • Journal of Physics Conference Series, January 2015, Institute of Physics Publishing

    Professor Martin O Leach

  107. PRESAGE®as a new calibration method for high intensity focused ultrasound therapy

    Article • Journal of Physics Conference Series, January 2015, Institute of Physics Publishing

    Professor Martin O Leach

  108. Use of the temporal median and trimmed mean mitigates effects of respiratory motion in multiple-acquisition abdominal diffusion imaging

    Article • Physics in Medicine and Biology, January 2015, Institute of Physics Publishing

    Professor Martin O Leach

  109. 143: Magnetic resonance imaging (MRI) in patients with non-small cell lung cancer (NSCLC) using active breathing coordinator motion control

    Article • Lung Cancer, January 2015, Elsevier

    Professor Martin O Leach

  110. Investigating the Influence of Flip Angle and k-Space Sampling on Dynamic Contrast-Enhanced MRI Breast Examinations

    Article • Academic Radiology, November 2014, Elsevier

    Professor Martin O Leach

  111. 540 Vemurafenib alters glucose utilization in BRAF-driven human melanoma cells

    Article • European Journal of Cancer, November 2014, Elsevier

    Professor Martin O Leach

  112. Abstract 2451: Insulin-like growth factor-1 receptor (IGF-1R) inhibitors downregulate p53 expression and upregulate the Warburg effect in paediatric glioblastoma cells

    Article • Cancer Research, October 2014, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  113. Interrogating Two Schedules of the AKT Inhibitor MK-2206 in Patients with Advanced Solid Tumors Incorporating Novel Pharmacodynamic and Functional Imaging Biomarkers

    Article • Clinical Cancer Research, September 2014, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  114. Erratum to: MRI breast screening in high-risk women: cancer detection and survival analysis

    Article • Breast Cancer Research and Treatment, September 2014, Springer Science + Business Media

    Professor Martin O Leach

  115. Lactate and Choline Metabolites Detected In Vitro by Nuclear Magnetic Resonance Spectroscopy Are Potential Metabolic Biomarkers for PI3K Inhibition in Pediatric Glioblastoma

    Article • PLoS ONE, August 2014, PLOS

    Professor Martin O Leach

  116. Poster Presentations

    Article • Luminescence, June 2014, Wiley

    Professor Martin O Leach

  117. Dichloroacetate induces autophagy in colorectal cancer cells and tumours

    Article • British Journal of Cancer, June 2014, Nature

    Gigin Lin, Professor Martin O Leach

  118. SU‐D‐18C‐04: The Feasibility of Quantifying MRI Contrast Agent in Pulsatile Flowing Blood Using DCE‐MRI

    Article • Medical Physics, May 2014, Wiley

    Professor Martin O Leach

  119. Assessment of Treatment Response by Total Tumor Volume and Global Apparent Diffusion Coefficient Using Diffusion-Weighted MRI in Patients with Metastatic Bone Disease: A Feasibility Study

    Article • PLoS ONE, April 2014, PLOS

    Professor Martin O Leach

  120. MRI breast screening in high-risk women: cancer detection and survival analysis

    Article • Breast Cancer Research and Treatment, April 2014, Springer Science + Business Media

    Professor Martin O Leach

  121. Reduced Warburg Effect in Cancer Cells Undergoing Autophagy: Steady- State 1H-MRS and Real-Time Hyperpolarized 13C-MRS Studies

    Article • PLoS ONE, March 2014, PLOS

    Gigin Lin, Professor Martin O Leach

  122. Clinical Proton MR Spectroscopy in Central Nervous System Disorders

    Article • Radiology, March 2014, Radiological Society of North America (RSNA)

    Professor Risto A Kauppinen, Professor Martin O Leach

  123. Quantitative PET and SPECT performance characteristics of the Albira Trimodal pre-clinical tomograph

    Article • Physics in Medicine and Biology, January 2014, Institute of Physics Publishing

    Professor Martin O Leach

  124. Development of a Hybrid Magnetic Resonance and Ultrasound Imaging System

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Professor Martin O Leach

  125. Wireless Accelerometer for MRI-Guided Interventional Procedures

    Article • Technologies, December 2013, MDPI AG

    Professor Martin O Leach

  126. Profiling metabolite changes in the neuronal differentiation of human striatal neural stem cells using 1H-magnetic resonance spectroscopy

    Article • Neuroreport, December 2013, Wolters Kluwer Health

    Professor Martin O Leach

  127. Comparison of three reference methods for the measurement of intracellular pH using 31 P MRS in healthy volunteers and patients with lymphoma

    Article • NMR in Biomedicine, November 2013, Wiley

    Professor Martin O Leach

  128. The role of pre-treatment diffusion-weighted MRI in predicting long-term outcome of colorectal liver metastasis

    Article • British Journal of Radiology, October 2013, British Institute of Radiology

    Professor Martin O Leach

  129. Model Free Approach to Kinetic Analysis of Real-Time Hyperpolarized 13C Magnetic Resonance Spectroscopy Data

    Article • PLoS ONE, September 2013, PLOS

    Professor Martin O Leach

  130. Noninvasive Phosphorus Magnetic Resonance Spectroscopic Imaging Predicts Outcome to First-line Chemotherapy in Newly Diagnosed Patients with Diffuse Large B-Cell Lymphoma

    Article • Academic Radiology, September 2013, Elsevier

    Professor Martin O Leach

  131. Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI

    Article • British Journal of Cancer, August 2013, Springer Science + Business Media

    Professor Martin O Leach

  132. Stacked Autoencoders for Unsupervised Feature Learning and Multiple Organ Detection in a Pilot Study Using 4D Patient Data

    Article • IEEE Transactions on Pattern Analysis and Machine Intelligence, August 2013, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Martin O Leach

  133. SU‐E‐J‐107: SEMAC MRI Metal Artifact Reduction Technique for Radiotherapy Planning Using CT/MRI Fusion

    Article • Medical Physics, June 2013, Wiley

    Professor Martin O Leach

  134. 1 H NMR and hyperpolarized 13 C NMR assays of pyruvate–lactate: a comparative study

    Article • NMR in Biomedicine, May 2013, Wiley

    Professor Martin O Leach

  135. MEK1/2 Inhibition Decreases Lactate in BRAF-Driven Human Cancer Cells

    Article • Cancer Research, May 2013, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  136. Multi-Frame SPRITE: A method for resolution enhancement of multiple-point SPRITE data

    Article • Journal of Magnetic Resonance, May 2013, Elsevier

    Professor Martin O Leach

  137. Comparison of free-breathing with navigator-controlled acquisition regimes in abdominal diffusion-weighted magnetic resonance images: Effect on ADC and IVIM statistics

    Article • Journal of Magnetic Resonance Imaging, April 2013, Wiley

    Professor Martin O Leach

  138. Abstract 5640: Picropodophyllin downregulates p53 and increases the Warburg effect in pediatric glioblastoma cells.

    Article • Cancer Research, April 2013, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  139. Reproducibility of Dynamic Contrast-enhanced MR Imaging: Why We Should Care

    Article • Radiology, March 2013, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  140. Improved intravoxel incoherent motion analysis of diffusion weighted imaging by data driven Bayesian modeling

    Article • Magnetic Resonance in Medicine, February 2013, Wiley

    Professor Martin O Leach

  141. Optimal age to start preventive measures in women withBRCA1/2mutations or high familial breast cancer risk

    Article • International Journal of Cancer, February 2013, Wiley

    Professor Martin O Leach

  142. First-in-Human Phase I Trial of Two Schedules of OSI-930, a Novel Multikinase Inhibitor, Incorporating Translational Proof-of-Mechanism Studies

    Article • Clinical Cancer Research, February 2013, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  143. The utility of whole-body diffusion-weighted MRI for delineating regions of interest in PET

    Article • Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment, February 2013, Elsevier

    Professor Martin O Leach

  144. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

    Article • Breast Cancer Research, January 2013, Springer Science + Business Media

    Professor Martin O Leach

  145. Breast dynamic contrast-enhanced examinations with fat suppression: Are contrast-agent uptake curves affected by magnetic field inhomogeneity?

    Article • European Radiology, December 2012, Springer Science + Business Media

    Professor Martin O Leach

  146. Abstract P4-11-05: Optimal age to start preventive measures in women with BRCA1/2 mutations or high familial breast cancer risk

    Article • Cancer Research, December 2012, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  147. Functional imaging in adult and paediatric brain tumours

    Article • Nature Reviews Clinical Oncology, November 2012, Springer Science + Business Media

    Professor Martin O Leach

  148. Advanced Solid Tumors Treated with Cediranib: Comparison of Dynamic Contrast-enhanced MR Imaging and CT as Markers of Vascular Activity

    Article • Radiology, November 2012, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  149. Informatics in Radiology: Development of a Research PACS for Analysis of Functional Imaging Data in Clinical Research and Clinical Trials

    Article • Radiographics, November 2012, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  150. Assessment of the dynamic range in dynamic contrast-enhanced magnetic resonance imaging breast examinations

    Article • Breast Cancer Research, November 2012, Springer Science + Business Media

    Professor Martin O Leach

  151. Measurement reproducibility of perfusion fraction and pseudodiffusion coefficient derived by intravoxel incoherent motion diffusion-weighted MR imaging in normal liver and metastases

    Article • European Radiology, October 2012, Springer Science + Business Media

    Professor Martin O Leach

  152. Whole-Body Diffusion-Weighted MRI: Tips, Tricks, and Pitfalls

    Article • American Journal of Roentgenology, August 2012, American Roentgen Ray Society

    Professor Martin O Leach

  153. 841 Non-invasive Imaging of Response to MEK Inhibition With Selumetinib (AZD6244, ARRY-142886) in a Human Colorectal Cancer Xenograft Using Diffusion-Weighted MRI

    Article • European Journal of Cancer, July 2012, Elsevier

    Professor Martin O Leach

  154. Differences in Natural History between Breast Cancers in BRCA1 and BRCA2 Mutation Carriers and Effects of MRI Screening-MRISC, MARIBS, and Canadian Studies Combined

    Article • Cancer Epidemiology Biomarkers & Prevention, June 2012, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  155. Combination of chemical suppression techniques for dual suppression of fat and silicone at diffusion-weighted MR imaging in women with breast implants

    Article • European Radiology, June 2012, Springer Science + Business Media

    Professor Martin O Leach

  156. Phase I Trial of Combretastatin A4 Phosphate (CA4P) in Combination with Bevacizumab in Patients with Advanced Cancer

    Article • Clinical Cancer Research, May 2012, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  157. Abstract B61: Picropodophyllin (PPP) increases glucose metabolism and lactate production in paediatric glioblastoma cells

    Article • Clinical Cancer Research, May 2012, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  158. Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging

    Article • European Radiology, May 2012, Springer Science + Business Media

    Professor Martin O Leach

  159. Evaluation of distortion correction of diffusion-weighted MR images of human cervix

    Article • May 2012, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Martin O Leach

  160. Neuroendocrine Tumor Liver Metastases: Use of Dynamic Contrast-enhanced MR Imaging to Monitor and Predict Radiolabeled Octreotide Therapy Response

    Article • Radiology, April 2012, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  161. Assessment of colorectal hepatic metastases by quantitative T2 relaxation time

    Article • European Journal of Radiology, April 2012, Elsevier

    Professor Martin O Leach

  162. Abstract 2501: Inhibition of the PI3K pathway potentiates temozolomide effects in pediatric glioblastoma and results in alterations in glucose and choline metabolism detected by MRS

    Article • Cancer Research, April 2012, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  163. Common Breast Cancer Susceptibility Variants in LSP1 and RAD51L1 Are Associated with Mammographic Density Measures that Predict Breast Cancer Risk

    Article • Cancer Epidemiology Biomarkers & Prevention, March 2012, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  164. Appearances of colorectal hepatic metastases at diffusion-weighted MRI compared with histopathology: initial observations

    Article • British Journal of Radiology, March 2012, Oxford University Press (OUP)

    Professor Martin O Leach

  165. Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy

    Article • BMC Research Notes, January 2012, Springer Science + Business Media

    Professor Martin O Leach

  166. An evaluation of motion compensation strategies and repeatability for abdominal 1H MR spectroscopy measurements in volunteer studies and clinical trials

    Article • NMR in Biomedicine, December 2011, Wiley

    Professor Martin O Leach

  167. Histone Deacetylase Inhibition Increases Levels of Choline Kinase   and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers

    Article • Cancer Research, December 2011, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  168. Computerized detection of breast lesions in multi-centre and multi-instrument DCE-MR data using 3D principal component maps and template matching

    Article • Physics in Medicine and Biology, November 2011, Institute of Physics Publishing

    Professor Martin O Leach

  169. Computed Diffusion-weighted MR Imaging May Improve Tumor Detection

    Article • Radiology, November 2011, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  170. Exploiting tumor metabolism for non-invasive imaging of the therapeutic activity of molecularly targeted anticancer agents

    Article • Cell Cycle, September 2011, Taylor & Francis

    Professor Martin O Leach

  171. Quantitative diffusion-weighted (DW) MR imaging of microcapillary perfusion and tissue diffusivity as biomarkers of response of renal cell carcinoma (RCC) to treatment with sunitinib.

    Article • Journal of Clinical Oncology, May 2011, American Society of Clinical Oncology (ASCO)

    Professor Martin O Leach

  172. Abstract 3788: Autophagy induced by DCA, PI3K inhibition or starvation results in reduced lactate production measured in real-time by DNP 13C MRS

    Article • Cancer Research, April 2011, American Association for Cancer Research (AACR)

    Gigin Lin, Professor Martin O Leach

  173. Phase I Trial of a Selective c-MET Inhibitor ARQ 197 Incorporating Proof of Mechanism Pharmacodynamic Studies

    Article • Journal of Clinical Oncology, April 2011, American Society of Clinical Oncology (ASCO)

    Professor Martin O Leach

  174. Abstract 5277: Non-invasive metabolic biomarkers of histone deacetylase inhibition in human colon cancer cells and tumors

    Article • Cancer Research, April 2011, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  175. Assessment of the effect of haematocrit-dependent arterial input functions on the accuracy of pharmacokinetic parameters in dynamic contrast-enhanced MRI

    Article • NMR in Biomedicine, February 2011, Wiley

    Professor Martin O Leach

  176. Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research

    Article • Neoplasia, February 2011, Elsevier

    Professor Martin O Leach

  177. Psychological impact and acceptability of magnetic resonance imaging and X-ray mammography: the MARIBS Study

    Article • British Journal of Cancer, February 2011, Springer Science + Business Media

    Professor Martin O Leach

  178. Optimising magnetic resonance imaging for preoperative staging and surgical planning in colon cancer at 1.5 tesla and 3.0 tesla.

    Article • Journal of Clinical Oncology, February 2011, American Society of Clinical Oncology (ASCO)

    Professor Martin O Leach

  179. A Bayesian hierarchical model for DCE-MRI to evaluate treatment response in a phase II study in advanced squamous cell carcinoma of the head and neck

    Article • Magnetic Resonance Materials in Physics Biology and Medicine, January 2011, Springer Science + Business Media

    Professor Martin O Leach

  180. Phosphorus Magnetic Resonance Spectroscopy Predicts Outcome to Chemotherapy In Patients with Diffuse Large B-Cell Lymphoma: A Prospective International Multicenter Analysis of a Pretreatment Metabolic Biomarker of Response

    Article • Blood, November 2010, American Society of Hematology

    Professor Martin O Leach

  181. Noninvasive detection of carboxypeptidase G2 activity in vivo

    Article • NMR in Biomedicine, October 2010, Wiley

    Professor Martin O Leach

  182. Dynamic contrast-enhanced MRI of neuroendocrine hepatic metastases: A feasibility study using a dual-input two-compartment model

    Article • Magnetic Resonance in Medicine, September 2010, Wiley

    Professor Martin O Leach

  183. Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition

    Article • Oncotarget, July 2010, Impact Journals, LLC

    Professor Martin O Leach

  184. The Phosphoinositide 3-Kinase Inhibitor PI-103 Downregulates Choline Kinase α Leading to Phosphocholine and Total Choline Decrease Detected by Magnetic Resonance Spectroscopy

    Article • Cancer Research, June 2010, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  185. Correlation of the intra-tumor phospholipid-related signatures determined noninvasively by phosphorus and hydrogen MR spectroscopy: An approach to increase the sensitivity and applicability of the technique to predict therapeutic outcome in non-Hodgkin...

    Article • Journal of Clinical Oncology, May 2010, American Society of Clinical Oncology (ASCO)

    Professor Martin O Leach

  186. Abstract 5083: Inhibition of MEK1/2 signaling in human BRAFV600E melanoma cells reduces glucose uptake and lactate dehydrogenase activity resulting in a time-dependent decrease in lactate production

    Article • Cancer Research, April 2010, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  187. Robustness of interactive intensity thresholding based breast density assessment in MR-mammography

    Article • March 2010, SPIE

    Professor Martin O Leach

  188. Virtual conferences becoming a reality

    Article • Nature Chemistry, March 2010, Springer Science + Business Media

    Professor Martin O Leach

  189. Abstract A72: Assessment of pyuvate dehydrogenase kinase inhibition by dichloroacetate in human colon carcinoma cells by dynamic hyperpolarized 13C MRS and steady state 1H MRS

    Article • Molecular Cancer Therapeutics, December 2009, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  190. Abstract A224: Noninvasive PD markers of a pyruvate dehydrogenase kinase inhibitor, dichloroacetate, in human colon carcinoma xenografts

    Article • Molecular Cancer Therapeutics, December 2009, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  191. Abstract A228: Noninvasive magnetic resonance spectroscopic PD markers of a minor-groove interstrand cross-linking agent (BN2629) in human colon carcinoma and melanoma xenografts

    Article • Molecular Cancer Therapeutics, December 2009, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  192. Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopy

    Article • British Journal of Cancer, November 2009, Springer Science + Business Media

    Professor Martin O Leach

  193. A phase I study of the nitroimidazole hypoxia marker SR4554 using 19F magnetic resonance spectroscopy

    Article • British Journal of Cancer, November 2009, Springer Science + Business Media

    Professor Martin O Leach

  194. Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study

    Article • November 2009, Springer Science + Business Media

    Professor Martin O Leach

  195. Hyperpolarized 13 C magnetic resonance detection of carboxypeptidase G2 activity

    Article • Magnetic Resonance in Medicine, September 2009, Wiley

    Professor Martin O Leach

  196. Cancers in BRCA1 and BRCA2 Carriers and in Women at High Risk for Breast Cancer: MR Imaging and Mammographic Features 1

    Article • Radiology, August 2009, Radiological Society of North America (RSNA)

    Dr Anna Middleton, Professor Martin O Leach

  197. Motion artifact correction in free-breathing abdominal MRI using overlapping partial samples to recover image deformations

    Article • Magnetic Resonance in Medicine, August 2009, Wiley

    Professor Martin O Leach

  198. Phase-cycled averaging for the suppression of residual magnetisation in SPI sequences

    Article • Journal of Magnetic Resonance, August 2009, Elsevier

    Professor Martin O Leach

  199. Eligibility for Magnetic Resonance Imaging Screening in the United Kingdom: Effect of Strict Selection Criteria and Anonymous DNA Testing on Breast Cancer Incidence in the MARIBS Study

    Article • Cancer Epidemiology Biomarkers & Prevention, June 2009, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  200. Quantitative imaging biomarkers in neuro-oncology

    Article • Nature Reviews Clinical Oncology, June 2009, Springer Science + Business Media

    Professor Martin O Leach

  201. Reproducibility and changes in the apparent diffusion coefficients of solid tumours treated with combretastatin A4 phosphate and bevacizumab in a two-centre phase I clinical trial

    Article • European Radiology, June 2009, Springer Science + Business Media

    Professor Martin O Leach

  202. A novel technique to monitor carboxypeptidase G2 expression in suicide gene therapy using19F magnetic resonance spectroscopy

    Article • NMR in Biomedicine, June 2009, Wiley

    Professor Martin O Leach

  203. Modulation of choline kinase activity in human cancer cells observed by dynamic31P NMR

    Article • NMR in Biomedicine, May 2009, Wiley

    Professor Martin O Leach

  204. Modulating the relaxivity of hyperpolarized substrates with gadolinium contrast agents

    Article • Contrast Media & Molecular Imaging, May 2009, Wiley

    Professor Martin O Leach

  205. An Exploratory Study Into the Role of Dynamic Contrast-Enhanced Magnetic Resonance Imaging or Perfusion Computed Tomography for Detection of Intratumoral Hypoxia in Head-and-Neck Cancer

    Article • International Journal of Radiation Oncology*Biology*Physics, May 2009, Elsevier

    Professor Martin O Leach

  206. Changes in choline metabolism as potential biomarkers of phospholipase C 1 inhibition in human prostate cancer cells

    Article • Molecular Cancer Therapeutics, May 2009, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  207. Optimizing functional parameter accuracy for breath-hold DCE-MRI of liver tumours

    Article • Physics in Medicine and Biology, March 2009, Institute of Physics Publishing

    Professor Martin O Leach

  208. Dynamic contrast-enhanced MRI for prostate cancer localization

    Article • British Journal of Radiology, February 2009, British Institute of Radiology

    Professor Martin O Leach

  209. Breast cancer screening in women at high risk using MRI

    Article • NMR in Biomedicine, January 2009, Wiley

    Professor Martin O Leach

  210. Comparison of Breast Density Assessments Based on Interactive Thresholding and Automated Fast Fuzzy c-means Clustering in Three-Dimensional MR Imaging

    Article • January 2009, Springer Science + Business Media

    Professor Martin O Leach

  211. 80 POSTER Inhibition of MEK1/2 signalling results in decreased levels of intracellular lactate in human melanoma and colorectal cancer cells as observed with magnetic resonance spectroscopy

    Article • European Journal of Cancer Supplements, October 2008, Elsevier

    Professor Martin O Leach

  212. A Pilot Study of Compositional Analysis of the Breast and Estimation of Breast Mammographic Density Using Three-Dimensional T1-Weighted Magnetic Resonance Imaging

    Article • Cancer Epidemiology Biomarkers & Prevention, September 2008, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  213. The value of magnetic resonance spectroscopy in tumour imaging

    Article • Archives of Disease in Childhood, September 2008, BMJ

    Professor Martin O Leach

  214. Heat shock protein 90 inhibitors modulate choline phospholipid profiles and metabolizing enzymes in human melanoma cells

    Article • European Journal of Cancer Supplements, July 2008, Elsevier

    Professor Martin O Leach

  215. Noninvasive Magnetic Resonance Spectroscopic Pharmacodynamic Markers of a Novel Histone Deacetylase Inhibitor, LAQ824, in Human Colon Carcinoma Cells and Xenografts

    Article • Neoplasia, April 2008, Elsevier

    Professor Martin O Leach

  216. Therapeutic Target Metabolism Observed Using Hyperpolarized15N Choline

    Article • Journal of the American Chemical Society, April 2008, American Chemical Society (ACS)

    Professor Martin O Leach

  217. Quantitative mapping of hepatic perfusion index using MR imaging: a potential reproducible tool for assessing tumour response to treatment with the antiangiogenic compound BIBF 1120, a potent triple angiokinase inhibitor

    Article • European Radiology, March 2008, Springer Science + Business Media

    Professor Martin O Leach

  218. Computationally efficient vascular input function models for quantitative kinetic modelling using DCE-MRI

    Article • Physics in Medicine and Biology, February 2008, Institute of Physics Publishing

    Professor Martin O Leach

  219. Detection of colorectal hepatic metastases using MnDPDP MR imaging and diffusion-weighted imaging (DWI) alone and in combination

    Article • European Radiology, January 2008, Springer Science + Business Media

    Professor Martin O Leach

  220. BRCA1 Mutation and Young Age Predict Fast Breast Cancer Growth in the Dutch, United Kingdom, and Canadian Magnetic Resonance Imaging Screening Trials

    Article • Clinical Cancer Research, December 2007, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  221. Distortion-correctedT2weighted MRI: a novel approach to prostate radiotherapy planning

    Article • British Journal of Radiology, November 2007, British Institute of Radiology

    Professor Martin O Leach

  222. O-58 The UK MARIBS study of MRI breast screening: progress on genetic and density projects

    Article • European Journal of Cancer Supplements, September 2007, Elsevier

    Professor Martin O Leach

  223. Registration of dynamic contrast-enhanced MRI using a progressive principal component registration (PPCR)

    Article • Physics in Medicine and Biology, August 2007, Institute of Physics Publishing

    Professor Martin O Leach

  224. Multiscale analysis of MR-mammography data

    Article • Zeitschrift für Medizinische Physik, August 2007, Elsevier

    Professor Martin O Leach

  225. Selective homonuclear Hartmann–Hahn for13C→13C polarization transfer in solution state NMR

    Article • Molecular Physics, July 2007, Taylor & Francis

    Professor Martin O Leach

  226. EU Directive 2004/40: field measurements of a 1.5 T clinical MR scanner

    Article • British Journal of Radiology, June 2007, British Institute of Radiology

    Professor Martin O Leach

  227. Bayesian estimation of pharmacokinetic parameters for DCE-MRI with a robust treatment of enhancement onset time

    Article • Physics in Medicine and Biology, April 2007, Institute of Physics Publishing

    Professor Martin O Leach

  228. Predicting Response of Colorectal Hepatic Metastasis: Value of Pretreatment Apparent Diffusion Coefficients

    Article • American Journal of Roentgenology, April 2007, American Roentgen Ray Society

    Professor Martin O Leach

  229. Quantitative evaluation of free-form deformation registration for dynamic contrast-enhanced MR mammography

    Article • Medical Physics, March 2007, Wiley

    Professor Martin O Leach

  230. American Cancer Society Guidelines for Breast Screening with MRI as an Adjunct to Mammography

    Article • CA A Cancer Journal for Clinicians, March 2007, Wiley

    Professor Martin O Leach

  231. Parametric mapping of the hepatic perfusion index with gadolinium-enhanced volumetric MRI

    Article • British Journal of Radiology, February 2007, Oxford University Press (OUP)

    Professor Martin O Leach

  232. Reference tissue quantification of DCE-MRI data without a contrast agent calibration

    Article • Physics in Medicine and Biology, January 2007, Institute of Physics Publishing

    Professor Martin O Leach

  233. Conformational exchange in pimonidazole—a hypoxia marker

    Article • Magnetic Resonance in Chemistry, January 2007, Wiley

    Professor Martin O Leach

  234. Dynamic MRI for imaging tumor microvasculature: Comparison of susceptibility and relaxivity techniques in pelvic tumors

    Article • Journal of Magnetic Resonance Imaging, January 2007, Wiley

    Professor Martin O Leach

  235. Measurements of occupational exposure to switched gradient and spatially-varying magnetic fields in areas adjacent to 1.5T clinical MRI systems

    Article • Journal of Magnetic Resonance Imaging, January 2007, Wiley

    Professor Martin O Leach

  236. Reproducibility of reference tissue quantification of dynamic contrast-enhanced data: comparison with a fixed vascular input function

    Article • Physics in Medicine and Biology, December 2006, Institute of Physics Publishing

    Professor Martin O Leach

  237. 562 POSTER Inhibition of MEK 1/2 signalling with Cl-1040 in human melanoma cells leads to alterations in phosphocholine metabolism

    Article • European Journal of Cancer Supplements, November 2006, Elsevier

    Professor Martin O Leach

  238. Cost-effectiveness of screening with contrast enhanced magnetic resonance imaging vs X-ray mammography of women at a high familial risk of breast cancer

    Article • British Journal of Cancer, October 2006, Springer Science + Business Media

    Professor Martin O Leach

  239. A test of performance of breast MRI interpretation in a multicentre screening study

    Article • Magnetic Resonance Imaging, September 2006, Elsevier

    Professor Martin O Leach

  240. Applications of magnetic resonance spectroscopy in radiotherapy treatment planning

    Article • British Journal of Radiology, September 2006, British Institute of Radiology

    Professor Martin O Leach

  241. MRI for breast cancer screening

    Article • Annals of Oncology, September 2006, Oxford University Press (OUP)

    Professor Martin O Leach

  242. Evaluation of response to treatment using DCE-MRI: the relationship between initial area under the gadolinium curve (IAUGC) and quantitative pharmacokinetic analysis

    Article • Physics in Medicine and Biology, July 2006, Institute of Physics Publishing

    Professor Martin O Leach

  243. An investigation of dose calculation accuracy in intensity-modulated radiotherapy of sites in the head & neck

    Article • Physica Medica, July 2006, Elsevier

    Professor Martin O Leach

  244. Magnetic resonance spectroscopy (MRS) in the investigation of cancer at The Royal Marsden Hospital and The Institute of Cancer Research

    Article • Physics in Medicine and Biology, June 2006, Institute of Physics Publishing

    Professor Martin O Leach

  245. Evaluation of a Prospective Scoring System Designed for a Multicenter Breast MR Imaging Screening Study

    Article • Radiology, June 2006, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  246. Factors influencing the accuracy of biomechanical breast models

    Article • Medical Physics, May 2006, Wiley

    Professor Martin O Leach

  247. Colorectal hepatic metastases: quantitative measurements using single-shot echo-planar diffusion-weighted MR imaging

    Article • European Radiology, May 2006, Springer Science + Business Media

    Professor Martin O Leach

  248. Minimally Invasive Pharmacokinetic and Pharmacodynamic Technologies in Hypothesis-Testing Clinical Trials of Innovative Therapies

    Article • JNCI Journal of the National Cancer Institute, May 2006, Oxford University Press (OUP)

    Professor Martin O Leach

  249. Prediction of Clinicopathologic Response of Breast Cancer to Primary Chemotherapy at Contrast-enhanced MR Imaging: Initial Clinical Results

    Article • Radiology, May 2006, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  250. Magnetic Resonance Imaging Workbench: Analysis and Visualization of Dynamic Contrast-enhanced MR Imaging Data

    Article • Radiographics, March 2006, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  251. Application of the chirp z-transform to MRI data

    Article • Journal of Magnetic Resonance, January 2006, Elsevier

    Professor Martin O Leach

  252. Evaluation of31P high-resolution magic angle spinning of intact tissue samples

    Article • NMR in Biomedicine, January 2006, Wiley

    Professor Martin O Leach

  253. Identification of magnetic resonance detectable metabolic changes associated with inhibition of phosphoinositide 3-kinase signaling in human breast cancer cells

    Article • Molecular Cancer Therapeutics, January 2006, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  254. In vivo31P MR spectral patterns and reproducibility in cancer patients studied in a multi-institutional trial

    Article • NMR in Biomedicine, January 2006, Wiley

    Professor Martin O Leach

  255. Noninvasive Magnetic Resonance Spectroscopic Pharmacodynamic Markers of the Choline Kinase Inhibitor MN58b in Human Carcinoma Models

    Article • Cancer Research, January 2006, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  256. Electromagnetic field exposure limitation and the future of MRI

    Article • British Journal of Radiology, November 2005, British Institute of Radiology

    Professor Martin O Leach

  257. Inversion recovery measurements in the presence of radiation damping and implications for evaluating contrast agents in magnetic resonance

    Article • Physics in Medicine and Biology, November 2005, Institute of Physics Publishing

    Professor Martin O Leach

  258. A Phase I study of the angiogenesis inhibitor SU5416 (semaxanib) in solid tumours, incorporating dynamic contrast MR pharmacodynamic end points

    Article • British Journal of Cancer, October 2005, Springer Science + Business Media

    Professor Martin O Leach

  259. Adiabatic half-passage pulses for measuring the polarization of highly non-equilibrium spin-systems

    Article • Chemical Physics Letters, October 2005, Elsevier

    Professor Martin O Leach

  260. Effects of platinum/taxane based chemotherapy on acute perfusion in human pelvic tumours measured by dynamic MRI

    Article • British Journal of Cancer, October 2005, Springer Science + Business Media

    Professor Martin O Leach

  261. Localized COSY and DQF-COSY1H-MRS sequences for investigating human tibial bone marrow in vivo and initial application to patients with acute leukemia

    Article • Journal of Magnetic Resonance Imaging, October 2005, Wiley

    Professor Martin O Leach

  262. Dual-contrast echo planar imaging with keyhole: application to dynamic contrast-enhanced perfusion studies

    Article • Physics in Medicine and Biology, September 2005, Institute of Physics Publishing

    Dr. Karl Zilles, Professor Martin O Leach

  263. Preliminary dose response study of a gel dosimeter using 2-Hydroxyethyl Methacrylate (HEMA)

    Article • Australasian Physical & Engineering Sciences in Medicine, September 2005, Springer Science + Business Media

    Professor Martin O Leach

  264. Reading Protocol for Dynamic Contrast-enhanced MR Images of the Breast: Sensitivity and Specificity Analysis

    Article • Radiology, September 2005, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  265. Evaluation of radiological features for breast tumour classification in clinical screening with machine learning methods

    Article • Artificial Intelligence in Medicine, June 2005, Elsevier

    Professor Martin O Leach

  266. A complete distortion correction for MR images: II. Rectification of static-field inhomogeneities by similarity-based profile mapping

    Article • Physics in Medicine and Biology, May 2005, Institute of Physics Publishing

    Professor Martin O Leach

  267. Identification of biliary metabolites of ifosfamide using 31P magnetic resonance spectroscopy and mass spectrometry

    Article • Cancer Chemotherapy and Pharmacology, May 2005, Springer Science + Business Media

    Professor Martin O Leach

  268. Processing of radical prostatectomy specimens for correlation of data from histopathological, molecular biological, and radiological studies: a new whole organ technique

    Article • Journal of Clinical Pathology, May 2005, BMJ

    Professor Martin O Leach

  269. Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS)

    Article • The Lancet, May 2005, Elsevier

    Professor Martin O Leach

  270. The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations

    Article • British Journal of Cancer, May 2005, Springer Science + Business Media

    Professor Martin O Leach

  271. Magnetic Resonance Spectroscopy Monitoring of Mitogen-Activated Protein Kinase Signaling Inhibition

    Article • Cancer Research, April 2005, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  272. A complete distortion correction for MR images: I. Gradient warp correction

    Article • Physics in Medicine and Biology, March 2005, Institute of Physics Publishing

    Professor Martin O Leach

  273. Antivascular cancer treatments: functional assessments by dynamic contrast-enhanced magnetic resonance imaging

    Article • Abdominal Imaging, February 2005, Springer Science + Business Media

    Professor Martin O Leach

  274. Proceedings of the Engineering and Physical Sciences Research Council Workshop—the development of functional imaging in the diagnosis, management and understanding of childhood brain tumours

    Article • Pediatric Blood & Cancer, February 2005, Wiley

    Professor Martin O Leach

  275. Quantitative assessment of the hepatic pharmacokinetics of the antimicrobial sitafloxacin in humans using in vivo19F magnetic resonance spectroscopy

    Article • British Journal of Clinical Pharmacology, February 2005, Wiley

    Professor Martin O Leach

  276. Burst imaging—Can it ever be useful in the clinic?

    Article • Concepts in Magnetic Resonance Part A, January 2005, Wiley

    Professor Martin O Leach

  277. Implementation and evaluation of CSI-localizedJ cross-polarization for detection of31P magnetic resonance spectra in vivo

    Article • Magnetic Resonance in Medicine, January 2005, Wiley

    Professor Martin O Leach

  278. Micro-coils for MR spectroscopy by deep silicon etching

    Article • Journal of Physics Conference Series, January 2005, Institute of Physics Publishing

    Professor Martin O Leach

  279. SOM-Based Wavelet Filtering for the Exploration of Medical Images

    Article • January 2005, Springer Science + Business Media

    Professor Martin O Leach

  280. Notices of Duplicate Publication

    Article • Radiology, December 2004, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  281. The dose distribution of low dose rate Cs-137 in intracavitary brachytherapy: comparison of Monte Carlo simulation, treatment planning calculation and polymer gel measurement

    Article • Physics in Medicine and Biology, November 2004, Institute of Physics Publishing

    Professor Martin O Leach

  282. Image fusion for dynamic contrast enhanced magnetic resonance imaging

    Article • BioMedical Engineering OnLine, October 2004, Springer Science + Business Media

    Professor Martin O Leach

  283. Investigations in vivo of the effects of carbogen breathing on 5-fluorouracil pharmacokinetics and physiology of solid rodent tumours

    Article • Cancer Chemotherapy and Pharmacology, October 2004, Springer Science + Business Media

    Professor Martin O Leach, Professor Godefridus J Peters

  284. Methodological standardization for a multi-institutionalin vivo trial of localized31P MR spectroscopy in human cancer research.In vitro and normal volunteer studies

    Article • NMR in Biomedicine, September 2004, Wiley

    Professor Martin O Leach

  285. Measurement of the three-dimensional distribution of radiation dose in grid therapy

    Article • Physics in Medicine and Biology, September 2004, Institute of Physics Publishing

    Professor Martin O Leach

  286. Investigation of microenvironmental factors influencing the longitudinal relaxation times of drugs and other compounds

    Article • Magnetic Resonance Imaging, September 2004, Elsevier

    Professor Martin O Leach

  287. Does vascular imaging with MRI predict response to neoadjuvant chemotherapy in primary breast cancer?

    Article • Journal of Clinical Oncology, July 2004, American Society of Clinical Oncology (ASCO)

    Professor Martin O Leach

  288. Noninvasive Measurements of Capecitabine Metabolism in Bladder Tumors Overexpressing Thymidine Phosphorylase by Fluorine-19 Magnetic Resonance Spectroscopy

    Article • Clinical Cancer Research, June 2004, American Association for Cancer Research (AACR)

    Professor Martin O Leach

  289. Alignment of dynamic contrast-enhanced MR volumes of the breast for a multicenter trial: an exemplar grid application

    Article • May 2004, SPIE

    Professor Martin O Leach

  290. Multiscale entropy analysis in dynamic contrast-enhanced MRI

    Article • May 2004, SPIE

    Professor Martin O Leach

  291. Visualization of multivariate image data using image fusion and perceptually optimized color scales based on sRGB

    Article • May 2004, SPIE

    Professor Martin O Leach

  292. Dose resolution in gel dosimetry: effect of uncertainty in the calibration function

    Article • Physics in Medicine and Biology, May 2004, Institute of Physics Publishing

    Professor Martin O Leach

  293. The use of gel dosimetry for verification of electron and photon treatment plans in carcinoma of the scalp

    Article • Physics in Medicine and Biology, April 2004, Institute of Physics Publishing

    Professor Martin O Leach

  294. Developing a quality control protocol for diffusion imaging on a clinical MRI system

    Article • Physics in Medicine and Biology, March 2004, Institute of Physics Publishing

    Professor Martin O Leach

  295. Evaluation of VEGF expression within breast cancer biopsies & tumour microvasculature assessment by multi-functional dynamic contrast-enhanced MRI

    Article • European Journal of Cancer Supplements, March 2004, Elsevier

    Professor Martin O Leach

  296. Effects of residual single-quantum coherences in intermolecular multiple-quantum coherence studies

    Article • Journal of Magnetic Resonance, February 2004, Elsevier

    Professor Martin O Leach

  297. Monitoring temozolomide treatment of low-grade glioma with proton magnetic resonance spectroscopy

    Article • British Journal of Cancer, February 2004, Springer Science + Business Media

    Professor Martin O Leach

  298. Nobel Prize in Physiology or Medicine 2003 awarded to Paul Lauterbur and Peter Mansfield for discoveries concerning magnetic resonance imaging

    Article • Physics in Medicine and Biology, January 2004, Institute of Physics Publishing

    Professor Martin O Leach

  299. Classification Improvement by Segmentation Refinement: Application to Contrast-Enhanced MR-Mammography

    Article • January 2004, Springer Science + Business Media

    Professor Martin O Leach

  300. Assessment of antiangiogenic and antivascular therapeutics using MRI: recommendations for appropriate methodology for clinical trials

    Article • British Journal of Radiology, December 2003, British Institute of Radiology

    Professor Martin O Leach

  301. Magnetic Resonance Spectroscopic Pharmacodynamic Markers of the Heat Shock Protein 90 Inhibitor 17-Allylamino,17-Demethoxygeldanamycin (17AAG) in Human Colon Cancer Models

    Article • JNCI Journal of the National Cancer Institute, November 2003, Oxford University Press (OUP)

    Professor Martin O Leach

  302. Human Gallbladder Bile: Noninvasive Investigation in Vivo with Single-Voxel1H MR Spectroscopy

    Article • Radiology, November 2003, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  303. Comparison of polarization transfer sequences for enhancement of signals in clinical31P MRS studies

    Article • Magnetic Resonance in Medicine, August 2003, Wiley

    Professor Martin O Leach

  304. Ifosfamide pharmacokinetics and hepatobiliary uptake in vivo investigated using single- and double-resonance31P MRS

    Article • Magnetic Resonance in Medicine, July 2003, Wiley

    Professor Martin O Leach

  305. Could assessment of glioma methylene lipid resonance byin vivo1H-MRS be of clinical value?

    Article • British Journal of Radiology, July 2003, British Institute of Radiology

    Professor Martin O Leach

  306. Non-invasive study of human gall bladder bilein vivousing1H-MR spectroscopy

    Article • British Journal of Radiology, July 2003, British Institute of Radiology

    Professor Martin O Leach

  307. Sliding window dual gradient echo (SW-dGRE):T1and proton resonance frequency (PRF) calibration for temperature imaging in polyacrylamide gel

    Article • Physics in Medicine and Biology, June 2003, Institute of Physics Publishing

    Professor Martin O Leach

  308. Hyperpolarising 13C for NMR studies using laser-polarised 129Xe: SPINOE vs thermal mixing

    Article • Chemical Physics Letters, April 2003, Elsevier

    Professor Martin O Leach

  309. Polymer gel measurement of dose homogeneity in the breast: comparing MLC intensity modulation with standard wedged delivery

    Article • Physics in Medicine and Biology, April 2003, Institute of Physics Publishing

    Professor Martin O Leach

  310. Potential role of magnetic resonance spectroscopy in assessment of tumour response in childhood cancer

    Article • European Journal of Cancer, April 2003, Elsevier

    Professor Martin O Leach

  311. Increased tumour extracellular pH induced by Bafilomycin A1 inhibits tumour growth and mitosis in vivo and alters 5-fluorouracil pharmacokinetics

    Article • European Journal of Cancer, March 2003, Elsevier

    Professor Martin O Leach

  312. Radiotherapy treatment planning of prostate cancer using magnetic resonance imaging alone

    Article • Radiotherapy and Oncology, February 2003, Elsevier

    Professor Martin O Leach

  313. Validation of nonrigid image registration using finite-element methods: application to breast MR images

    Article • IEEE Transactions on Medical Imaging, February 2003, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Martin O Leach

  314. Earlyin vivodetection of metabolic response: a pilot study of1H MR spectroscopy in extracranial lymphoma and germ cell tumours

    Article • British Journal of Radiology, December 2002, Oxford University Press (OUP)

    Professor Martin O Leach

  315. Comparison between radiological and artificial neural network diagnosis in clinical screening

    Article • Physiological Measurement, October 2002, Institute of Physics Publishing

    Professor Martin O Leach

  316. What is the recall rate of breast MRI when used for screening asymptomatic women at high risk?

    Article • Magnetic Resonance Imaging, September 2002, Elsevier

    Professor Martin O Leach

  317. Comparison of biomechanical breast models: a case study

    Article • May 2002, SPIE

    Professor Martin O Leach

  318. Finite-element based validation of nonrigid registration using single- and multilevel free-form deformations: application to contrast-enhanced MR mammography

    Article • May 2002, SPIE

    Professor Martin O Leach

  319. A model to assess SAR for surface coil magnetic resonance spectroscopy measurements

    Article • Physics in Medicine and Biology, May 2002, Institute of Physics Publishing

    Professor Martin O Leach

  320. Human rectal adenocarcinoma: Demonstration of1H-MR spectra in vivo at 1.5 T

    Article • Magnetic Resonance in Medicine, March 2002, Wiley

    Professor Martin O Leach

  321. Apoptosis is associated with triacylglycerol accumulation in Jurkat T-cells

    Article • British Journal of Cancer, March 2002, Springer Science + Business Media

    Professor Martin O Leach

  322. An algorithm for the optimum combination of data from arbitrary magnetic resonance phased array probes

    Article • Physics in Medicine and Biology, January 2002, Institute of Physics Publishing

    Professor Martin O Leach

  323. Applications of sliding window reconstruction with cartesian sampling for dynamic contrast enhanced MRI

    Article • NMR in Biomedicine, January 2002, Wiley

    Professor Martin O Leach

  324. Assessing changes in tumour vascular function using dynamic contrast-enhanced magnetic resonance imaging

    Article • NMR in Biomedicine, January 2002, Wiley

    Professor Martin O Leach

  325. Reproducibility of quantitative dynamic MRI of normal human tissues

    Article • NMR in Biomedicine, January 2002, Wiley

    Professor Martin O Leach

  326. The effect of Gd-DTPA on T1-weighted choline signal in human brain tumours

    Article • Magnetic Resonance Imaging, January 2002, Elsevier

    Professor Martin O Leach

  327. Validation of Volume-Preserving Non-rigid Registration: Application to Contrast-Enhanced MR-Mammography

    Article • January 2002, Springer Science + Business Media

    Professor Martin O Leach

  328. Measuring changes in human tumour vasculature in response to therapy using functional imaging techniques

    Article • British Journal of Cancer, October 2001, Springer Science + Business Media

    Professor Martin O Leach

  329. In vivo hyperpolarized 129Xe NMR spectroscopy in tumors

    Article • Magnetic Resonance in Medicine, August 2001, Wiley

    Professor Martin O Leach

  330. Effects of Abstinence From Alcohol on the Broad Phospholipid Signal in Human Brain: An In Vivo 31P Magnetic Resonance Spectroscopy Study

    Article • Alcoholism Clinical and Experimental Research, August 2001, Wiley

    Professor Martin O Leach

  331. Pre-processed image reconstruction applied to breast and brain MR imaging

    Article • Physiological Measurement, August 2001, Institute of Physics Publishing

    Professor Martin O Leach

  332. The quantitative 19 F-imaging of albumin at 1.5 T: a potential in-vivo tool

    Article • Magnetic Resonance Imaging, July 2001, Elsevier

    Professor Martin O Leach

  333. Numerical evaluation of shaped surface coil sensitivity at 63 MHz

    Article • Physics in Medicine and Biology, June 2001, Institute of Physics Publishing

    Professor Martin O Leach

  334. Radio-frequency probe for 1H decoupled 31P MRS of the head and neck region

    Article • Magnetic Resonance Imaging, June 2001, Elsevier

    Professor Martin O Leach

  335. Effects of Androgen Deprivation on Prostatic Morphology and Vascular Permeability Evaluated with MR Imaging

    Article • Radiology, February 2001, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  336. Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells

    Article • British Journal of Cancer, January 2001, Springer Science + Business Media

    Professor Martin O Leach

  337. Effects of Chronic Alcohol Consumption on the Broad Phospholipid Signal in Human Brain: An In Vivo 31P MRS Study

    Article • Alcoholism Clinical and Experimental Research, January 2001, Wiley

    Professor Martin O Leach

  338. A modified polymer gel for radiotherapy dosimetry: assessment by MRI and MRS

    Article • Physics in Medicine and Biology, October 2000, Institute of Physics Publishing

    Professor Martin O Leach

  339. Magnetic resonance imaging screening in women at genetic risk of breast cancer: imaging and analysis protocol for the UK multicentre study

    Article • Magnetic Resonance Imaging, September 2000, Elsevier

    Professor Martin O Leach

  340. Radiation dosimetry using polymer gels: methods and applications.

    Article • British Journal of Radiology, September 2000, Oxford University Press (OUP)

    Professor Martin O Leach

  341. Implications of respiratory motion for the quantification of 2D MR spectroscopic imaging data in the abdomen

    Article • Physics in Medicine and Biology, July 2000, Institute of Physics Publishing

    Professor Martin O Leach

  342. Radiotherapy planning of the pelvis using distortion corrected MR images: the removal of system distortions

    Article • Physics in Medicine and Biology, July 2000, Institute of Physics Publishing

    Professor Martin O Leach

  343. 1H decoupling for in vivo 19F MRS studies using the time‐share modulation method on a clinical 1.5 T NMR system

    Article • Magnetic Resonance in Medicine, July 2000, Wiley

    Professor Martin O Leach

  344. On the oxygenation‐dependent 129Xe T 1 in blood

    Article • NMR in Biomedicine, June 2000, Wiley

    Professor Martin O Leach

  345. High-resolution segmented EPI in a motor task fMRI study

    Article • Magnetic Resonance Imaging, May 2000, Elsevier

    Professor Martin O Leach

  346. The reproducibility of polyacrylamide gel dosimetry applied to stereotactic conformal radiotherapy

    Article • Physics in Medicine and Biology, April 2000, Institute of Physics Publishing

    Professor Martin O Leach

  347. Hyperpolarized129Xe NMR as a probe for blood oxygenation

    Article • Magnetic Resonance in Medicine, April 2000, Wiley

    Professor Martin O Leach

  348. Magnetic resonance spectroscopy in the evaluation of neurotoxicity following cranial irradiation for childhood cancer.

    Article • British Journal of Radiology, April 2000, Oxford University Press (OUP)

    Professor Martin O Leach

  349. Protocol for a national multi-centre study of magnetic resonance imaging screening in women at genetic risk of breast cancer

    Article • The Breast, April 2000, Elsevier

    Professor Martin O Leach

  350. Rationale for a national multi-centre study of magnetic resonance imaging screening in women at genetic risk of breast cancer

    Article • The Breast, April 2000, Elsevier

    Professor Martin O Leach

  351. Surface-coil polarization transfer for monitoring tissue metabolism in vivo

    Article • Magnetic Resonance in Medicine, April 2000, Wiley

    Professor Martin O Leach

  352. Surface-coil polarization transfer for monitoring tissue metabolism in vivo

    Article • Magnetic Resonance in Medicine, April 2000, Wiley

    Professor Martin O Leach

  353. Optimized MR imaging for polyacrylamide gel dosimetry

    Article • Physics in Medicine and Biology, March 2000, Institute of Physics Publishing

    Professor Martin O Leach

  354. Proton spectroscopic imaging of polyacrylamide gel dosimeters for absolute radiation dosimetry

    Article • Physics in Medicine and Biology, March 2000, Institute of Physics Publishing

    Professor Martin O Leach

  355. Breast imaging technology Application of magnetic resonance imaging to angiogenesis in breast cancer

    Article • Breast Cancer Research, February 2000, Springer Science + Business Media

    Professor Martin O Leach

  356. Imaging biochemistry: applications to breast cancer

    Article • Breast Cancer Research, February 2000, Springer Science + Business Media

    Professor Martin O Leach

  357. Dynamic Contrast Enhanced MRI of Prostate Cancer: Correlation with Morphology and Tumour Stage, Histological Grade and PSA

    Article • Clinical Radiology, February 2000, Elsevier

    Professor Martin O Leach

  358. Improving image quality and T1 measurements using saturation recovery turboFLASH with an approximate K-space normalisation filter

    Article • Magnetic Resonance Imaging, February 2000, Elsevier

    Professor Martin O Leach

  359. Preclinical development of noninvasive vascular occlusion with focused ultrasonic surgery for fetal therapy

    Article • American Journal of Obstetrics and Gynecology, February 2000, Elsevier

    Professor Martin O Leach

  360. SAR and tissue heating with a clinical31P MRS protocol using surface coils, adiabatic pulses, and proton-decoupling

    Article • Magnetic Resonance in Medicine, January 2000, Wiley

    Professor Martin O Leach

  361. Gallbladder localization of19F MRS catabolite signals in patients receiving bolus and protracted venous infusional 5-fluorouracil

    Article • Magnetic Resonance in Medicine, January 2000, Wiley

    Professor Martin O Leach

  362. Initial measurements of ifosfamide and cyclophosphamide in patients using31P MRS: Pulse-and-acquire, decoupling, and polarization transfer

    Article • Magnetic Resonance in Medicine, January 2000, Wiley

    Professor Martin O Leach

  363. 1H decoupling for in vivo19F MRS studies using the time-share modulation method on a clinical 1.5 T NMR system

    Article • Magnetic Resonance in Medicine, January 2000, Wiley

    Professor Martin O Leach

  364. Proton magnetic resonance spectroscopy (1H-MRS) of the brain following high-dose methotrexate treatment for childhood cancer

    Article • Medical and Pediatric Oncology, January 2000, Wiley

    Professor Martin O Leach

  365. Intravenous delivery of hyperpolarized129Xe: a compartmental model

    Article • NMR in Biomedicine, January 2000, Wiley

    Professor Martin O Leach

  366. On the oxygenation-dependent129XeT1 in blood

    Article • NMR in Biomedicine, January 2000, Wiley

    Professor Martin O Leach

  367. Dynamic contrast-enhanced MRI in the differentiation of breast tumors: User-defined versus semi-automated region-of-interest analysis

    Article • Journal of Magnetic Resonance Imaging, December 1999, Wiley

    Professor Martin O Leach

  368. Measurement of the extracellular pH of solid tumours in mice by magnetic resonance spectroscopy: a comparison of exogenous19F and31P probes

    Article • NMR in Biomedicine, December 1999, Wiley

    Professor Martin O Leach

  369. Signal modulation in1H magnetic resonance spectroscopy using contrast agents: Proton relaxivities of choline, creatine, andN-acetylaspartate

    Article • Magnetic Resonance in Medicine, December 1999, Wiley

    Professor Martin O Leach

  370. Dynamic contrast‐enhanced MRI in the differentiation of breast tumors: User‐defined versus semi‐automated region‐of‐interest analysis

    Article • Journal of Magnetic Resonance Imaging, December 1999, Wiley

    Professor Martin O Leach

  371. Experimental 3D dosimetry around a high-dose-rate clinical192Ir source using a polyacrylamide gel (PAG) dosimeter

    Article • Physics in Medicine and Biology, September 1999, Institute of Physics Publishing

    Professor Martin O Leach

  372. Comparison and Evaluation of Rigid, Affine, and Nonrigid Registration of Breast MR Images

    Article • Journal of Computer Assisted Tomography, September 1999, Wolters Kluwer Health

    Professor Martin O Leach

  373. Dynamics of polymerization in polyacrylamide gel (PAG) dosimeters: (I) ageing and long-term stability

    Article • Physics in Medicine and Biology, July 1999, Institute of Physics Publishing

    Professor Martin O Leach

  374. Dynamics of polymerization in polyacrylamide gel (PAG) dosimeters: (II) modelling oxygen diffusion

    Article • Physics in Medicine and Biology, July 1999, Institute of Physics Publishing

    Professor Martin O Leach

  375. Comparison of MRI with CT for the radiotherapy planning of prostate cancer: a feasibility study.

    Article • British Journal of Radiology, June 1999, Oxford University Press (OUP)

    Professor Martin O Leach

  376. Evaluating the effect of rectal distension and rectal movement on prostate gland position using cine MRI

    Article • International Journal of Radiation Oncology*Biology*Physics, June 1999, Elsevier

    Professor Martin O Leach

  377. Comparison and evaluation of rigid and nonrigid registration of breast MR images

    Article • May 1999, SPIE

    Professor Martin O Leach

  378. Magnetic resonance detects metabolic changes associated with chemotherapy-induced apoptosis

    Article • British Journal of Cancer, May 1999, Springer Science + Business Media

    Professor Martin O Leach

  379. Spin-lattice relaxation of laser-polarized xenon in human blood

    Article • Proceedings of the National Academy of Sciences, March 1999, Proceedings of the National Academy of Sciences

    Professor Martin O Leach

  380. Perfluorocarbon emulsions as intravenous delivery media for hyperpolarized xenon

    Article • Magnetic Resonance in Medicine, March 1999, Wiley

    Professor Martin O Leach

  381. Vascular occlusion using focused ultrasound surgery for use in fetal medicine

    Article • European Journal of Ultrasound, March 1999, Elsevier

    Professor Martin O Leach

  382. Perfluorocarbon emulsions as intravenous delivery media for hyperpolarized xenon

    Article • Magnetic Resonance in Medicine, March 1999, Wiley

    Professor Martin O Leach

  383. Nonrigid registration using free-form deformations: application to breast MR images

    Article • IEEE Transactions on Medical Imaging, January 1999, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Martin O Leach

  384. Intravascular delivery of hyperpolarized129Xenon forin vivo MRI

    Article • Applied Magnetic Resonance, December 1998, Springer Science + Business Media

    Professor Martin O Leach

  385. Measurements of human breast cancer using magnetic resonance spectroscopy: a review of clinical measurements and a report of localized31P measurements of response to treatment

    Article • NMR in Biomedicine, November 1998, Wiley

    Professor Jonathan C Sharp, Professor Martin O Leach

  386. Absolute metabolite quantification by in vivo NMR spectroscopy: I. introduction, objectives and activities of a concerted action in biomedical research

    Article • Magnetic Resonance Imaging, November 1998, Elsevier

    Professor Martin O Leach

  387. Absolute metabolite quantification by in vivo NMR spectroscopy: II. a multicentre trial of protocols for in vivo localised proton studies of human brain

    Article • Magnetic Resonance Imaging, November 1998, Elsevier

    Professor Martin O Leach

  388. In VivoMultiple Spin Echoes

    Article • Journal of Magnetic Resonance, November 1998, Elsevier

    Professor Martin O Leach

  389. Measuring diffusion of xenon in solution with hyperpolarized 129Xe NMR

    Article • Chemical Physics Letters, November 1998, Elsevier

    Professor Martin O Leach

  390. Improving calibration accuracy in gel dosimetry

    Article • Physics in Medicine and Biology, October 1998, Institute of Physics Publishing

    Professor Martin O Leach

  391. An investigation into the dosimetry of a nine-field tomotherapy irradiation using BANG-gel dosimetry

    Article • Physics in Medicine and Biology, May 1998, Institute of Physics Publishing

    Professor Martin O Leach

  392. Focused ultrasound surgery-induced vascular occlusion in fetal medicine

    Article • April 1998, SPIE

    Professor Martin O Leach

  393. Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells

    Article • British Journal of Cancer, March 1998, Springer Science + Business Media

    Professor Martin O Leach

  394. MRIW: parametric analysis software for contrast-enhanced dynamic MR imaging in cancer.

    Article • Radiographics, March 1998, Radiological Society of North America (RSNA)

    Professor Martin O Leach

  395. A Simple Phantom to Locate the Origin of MRI Ghost Artefacts

    Article • Magnetic Resonance Imaging, January 1998, Elsevier

    Professor Martin O Leach

  396. Non-rigid registration of breast MR images using mutual information

    Article • January 1998, Springer Science + Business Media

    Professor Martin O Leach

  397. A pharmacokinetic and pharmacodynamic study In vivo of human HT29 tumours using 19F and 31P magnetic resonance spectroscopy

    Article • European Journal of Cancer, December 1997, Elsevier

    Professor Martin O Leach

  398. Implementation and evaluation of frequency offset corrected inversion (FOCI) pulses on a clinical MR system

    Article • Magnetic Resonance in Medicine, November 1997, Wiley

    Professor Martin O Leach

  399. Reconstruction of elastic modulus distribution from envelope detected B-mode data

    Article • European Journal of Ultrasound, October 1997, Elsevier

    Professor Martin O Leach

  400. Probing tumor microvascularity by measurement, analysis and display of contrast agent uptake kinetics

    Article • Journal of Magnetic Resonance Imaging, May 1997, Wiley

    Professor Martin O Leach

  401. Visual detectability of elastic contrast in real-time ultrasound images

    Article • April 1997, SPIE

    Professor Martin O Leach

  402. Quantification of phosphorus metabolites in human calf muscle and soft-tissue tumours from localized MR spectra acquired using surface coils

    Article • Physics in Medicine and Biology, April 1997, Institute of Physics Publishing

    Professor Martin O Leach

  403. MRI study of hepatic tumours following high intensity focused ultrasound surgery.

    Article • British Journal of Radiology, February 1997, Oxford University Press (OUP)

    Professor Martin O Leach

  404. Magnetic resonance imaging (MRI): considerations and applications in radiotherapy treatment planning

    Article • Radiotherapy and Oncology, January 1997, Elsevier

    Professor Martin O Leach

  405. MRI in the evaluation of late bone marrow changes following bone marrow transplantation

    Article • British Journal of Radiology, December 1996, Oxford University Press (OUP)

    Professor Martin O Leach

  406. Simultaneous localized 1H STEAM/31P ISIS spectroscopy in Vivo

    Article • Magnetic Resonance in Medicine, April 1996, Wiley

    Professor Martin O Leach

  407. Measurement of plasma 5-fluorouracil by high-performance liquid chromatography with comparison of results to tissue drug levels observed using in vivo 19F magnetic resonance spectroscopy in patients on a protracted venous infusion with or without inter...

    Article • Annals of Oncology, January 1996, Elsevier

    Professor Martin O Leach

  408. Increased noe enhancement in 1h decoupled 31p mrs

    Article • Magnetic Resonance in Medicine, December 1995, Wiley

    Professor Martin O Leach

  409. Pharmacokinetics of the 13C labeled anticancer agent temozolomide detected in vivo by selective cross‐polarization transfer

    Article • Magnetic Resonance in Medicine, September 1995, Wiley

    Professor Martin O Leach

  410. Quantification of signal selection efficiency, extra volume suppression and contamination for ISIS, STEAM and PRESS localized1H NMR spectroscopy using an EEC localization test object

    Article • Physics in Medicine and Biology, July 1995, Institute of Physics Publishing

    Professor Martin O Leach

  411. Calculation of Sensitivity Correction Factors for Surface Coil MRS

    Article • Magnetic Resonance in Medicine, January 1995, Wiley

    Professor Martin O Leach

  412. On doubling the signal in localised stimulated echo measurements

    Article • Magnetic Resonance Imaging, January 1995, Elsevier

    Professor Martin O Leach

  413. Quality assessment in in vivo NMR spectroscopy: II. A protocol for quality assessment

    Article • Magnetic Resonance Imaging, January 1995, Elsevier

    Professor Martin O Leach

  414. Quality assessment in in vivo NMR spectroscopy: III. Clinical test objects: Design, construction, and solutions

    Article • Magnetic Resonance Imaging, January 1995, Elsevier

    Professor Martin O Leach

  415. Quality assessment in in vivo NMR spectroscopy: IV. A multicentre trial of test objects and protocols for performance assessment in clinical NMR spectroscopy

    Article • Magnetic Resonance Imaging, January 1995, Elsevier

    Professor Martin O Leach

  416. A gradient scheme suitable for localized shimming and in vivo1H/31P STEAM and ISIS NMR spectroscopy

    Article • Magnetic Resonance in Medicine, December 1994, Wiley

    Professor Martin O Leach

  417. Reducing motion artifacts in in vivo magnetic resonance imaging measurements of relaxation times

    Article • British Journal of Radiology, December 1994, Oxford University Press (OUP)

    Professor Martin O Leach

  418. International Workshop on Standardization in Clinical Magnetic Resonance Spectroscopy Measurements: Proceedings and recommendations

    Article • Academic Radiology, October 1994, Elsevier

    Professor Martin O Leach

  419. In vivo monitoring of fluoropyrimidine metabolites

    Article • Anti-Cancer Drugs, June 1994, Wolters Kluwer Health

    Professor Martin O Leach

  420. A Phase-Encoded Selection Technique (PEST) for Slice Selection without Resonant-Frequency-Offset Errors

    Article • Journal of Magnetic Resonance Series B, February 1994, Elsevier

    Professor Jonathan C Sharp, Professor Martin O Leach

  421. A rapid interleaved method for measuring signal intensity curves in both blood and tissue during contrast agent administration

    Article • Magnetic Resonance in Medicine, December 1993, Wiley

    Professor Martin O Leach

  422. Phospholipid metabolites, prognosis and proliferation in human breast carcinoma

    Article • NMR in Biomedicine, September 1993, Wiley

    Professor Martin O Leach

  423. The non-invasive monitoring of low dose, infusional 5-fluorouracil and its modulation by interferon-α using in vivo 19F magnetic resonance spectroscopy in patients with colorectal cancer: A pilot study

    Article • Annals of Oncology, August 1993, Elsevier

    Professor Martin O Leach

  424. The effect of oestrogen ablation on the phospholipid metabolite content of primary and transplanted rat mammary tumours

    Article • NMR in Biomedicine, May 1993, Wiley

    Professor Martin O Leach

  425. Radial diffusion coefficient mapping

    Article • British Journal of Radiology, October 1992, Oxford University Press (OUP)

    Professor Martin O Leach

  426. Practicalities of localization in animal and human tumours

    Article • NMR in Biomedicine, September 1992, Wiley

    Professor Martin O Leach

  427. Fast and accurate measurements of T1 using a multi‐readout single inversion‐recovery sequence

    Article • Magnetic Resonance in Medicine, July 1992, Wiley

    Professor Martin O Leach

  428. Threshold voltages for hyperbolic secant inversion pulses

    Article • NMR in Biomedicine, May 1992, Wiley

    Professor Martin O Leach

  429. A two‐point volume localized T1 measurement sequence for in vivo spectroscopy using a surface coil

    Article • NMR in Biomedicine, March 1992, Wiley

    Professor Martin O Leach

  430. Quantitative magnetic resonance spectroscopy by optimized numerical curve fitting

    Article • NMR in Biomedicine, March 1992, Wiley

    Professor Martin O Leach

  431. Rapid localization of concave volumes by conformal NMR spectroscopy

    Article • Magnetic Resonance in Medicine, February 1992, Wiley

    Professor Martin O Leach

  432. A single-shot shimming sequence using low-power RF noise pulses for localized in vivo NMR spectroscopy

    Article • Physics in Medicine and Biology, January 1992, Institute of Physics Publishing

    Professor Jonathan C Sharp, Professor Martin O Leach

  433. The effect of intra‐tumour heterogeneity on the distribution of phosphorus‐containing metabolites within human breast tumours: An In Vitro study using 31P NMR spectroscopy

    Article • NMR in Biomedicine, December 1991, Wiley

    Professor Martin O Leach

  434. The phosphocholine and glycerophosphocholine content of an oestrogen-sensitive rat mammary tumour correlates strongly with growth rate

    Article • British Journal of Cancer, November 1991, Springer Science + Business Media

    Professor Martin O Leach

  435. A phase II clinical and pharmacokinetic study of Lonidamine in patients with advanced breast cancer

    Article • British Journal of Cancer, September 1991, Springer Science + Business Media

    Professor Martin O Leach

  436. The water resonance as an alternative pH reference: Relevance to in Vivo31P NMR localized spectroscopy studies

    Article • Magnetic Resonance in Medicine, June 1991, Wiley

    Professor Martin O Leach

  437. A comparison of in vivo and in vitro 31P NMR spectra from human breast tumours: variations in phospholipid metabolism

    Article • British Journal of Cancer, April 1991, Springer Science + Business Media

    Professor Martin O Leach

  438. A simple method for the restoration of signal polarity in multi‐image inversion recovery sequences for measuring T1

    Article • Magnetic Resonance in Medicine, March 1991, Wiley

    Professor Martin O Leach

  439. A quantitative analysis of the accuracy of In Vivo pH measurements with 31P NMR spectroscopy: Assessment of pH measurement methodology

    Article • NMR in Biomedicine, February 1991, Wiley

    Professor Martin O Leach

  440. Comparison of 5-Fluorouracil pharmacokinetics following intraperitoneal and intravenous administration using in vivo  19F magnetic resonance spectroscopy

    Article • British Journal of Radiology, July 1990, Oxford University Press (OUP)

    Professor Martin O Leach

  441. An assessment of the sensitivity of in vivo  31P nuclear magnetic resonance spectroscopy as a means of detecting pH heterogeneity in tumours: a simulation study

    Article • British Journal of Radiology, February 1990, Oxford University Press (OUP)

    Professor Martin O Leach

  442. Installation of an ambient‐temperature control system in a 1.5‐tesla whole body system to facilitate animal studies

    Article • Medical Physics, November 1989, Wiley

    Professor Martin O Leach

  443. The use of an improved inversion pulse with the Spin‐Echo/ inversion‐recovery sequence to give increased accuracy and reduced imaging time for T1 measurements

    Article • Magnetic Resonance in Medicine, November 1989, Wiley

    Professor Martin O Leach

  444. Conformal NMR spectroscopy: Accurate localization to noncuboidal volumes with optimum SNR

    Article • Magnetic Resonance in Medicine, September 1989, Wiley

    Professor Martin O Leach

  445. pH calibration curve at 1.5 Tesla

    Article • Physics in Medicine and Biology, September 1989, Institute of Physics Publishing

    Professor Martin O Leach

  446. IN-VIVO 31P MAGNETIC RESONANCE SPECTROSCOPY FOR MONITORING TREATMENT RESPONSE IN BREAST CANCER

    Article • The Lancet, June 1989, Elsevier

    Professor Martin O Leach

  447. The performance characteristics of a simulator-based CT scanner

    Article • IEEE Transactions on Medical Imaging, June 1988, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Martin O Leach

  448. Clinical trials of the prototype Rutherford Appleton Laboratory MWPC positron camera at the Royal Marsden Hospital

    Article • Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment, June 1988, Elsevier

    Professor Martin O Leach

  449. Clinical dosimetry for radiotherapy to the breast based on imaging with the prototype Royal Marsden Hospital CT simulator

    Article • Physics in Medicine and Biology, July 1987, Institute of Physics Publishing

    Professor Martin O Leach

  450. Measurement of radiation dose to the thyroid using positron emission tomography

    Article • British Journal of Radiology, March 1987, Oxford University Press (OUP)

    Professor Martin O Leach

  451. The development of high‐efficiency cathode converters for a multiwire proportional chamber positron camera

    Article • Medical Physics, September 1986, Wiley

    Professor Martin O Leach

  452. The design and use of a dual-frequency surface coil providing proton images for improved localization in 3 1 P spectroscopy of small lesions

    Article • Medical Physics, July 1986, Wiley

    Professor Martin O Leach

  453. 3D positron emission tomography: preliminary results

    Article • British Journal of Radiology, April 1986, Oxford University Press (OUP)

    Professor Martin O Leach

  454. An X-ray detector system and modified simulator providing CT images for radiotherapy dosimetry planning

    Article • Physics in Medicine and Biology, April 1985, Institute of Physics Publishing

    Professor Martin O Leach

  455. Constrained deconvolution of SPECT liver tomograms by direct digital image restoration

    Article • Medical Physics, January 1985, Wiley

    Professor Martin O Leach

  456. A clinical evaluation of a prototype positron camera for longitudinal emission tomography

    Article • British Journal of Radiology, December 1984, Oxford University Press (OUP)

    Professor Martin O Leach

  457. Reconstructions from a Nonstandard CT Scanner

    Article • IEEE Transactions on Medical Imaging, December 1984, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Martin O Leach

  458. The release rate of37Ar from human subjects following intravenous injection

    Article • Physics in Medicine and Biology, July 1984, Institute of Physics Publishing

    Professor Martin O Leach

  459. The measurement of resolution in single photon emission computerised tomography

    Article • Physics in Medicine and Biology, March 1984, Institute of Physics Publishing

    Professor Martin O Leach

  460. Tumour localisation in oncology using positron emitting radiopharmaceuticals and a multiwire proportional chamber positron camera; Techniques for 3D deconvolution

    Article • Nuclear Instruments and Methods in Physics Research, March 1984, Elsevier

    Professor Martin O Leach

  461. A comparison between 180° and 360° data reconstruction in single photon emission computed tomography of the liver and spleen

    Article • British Journal of Radiology, December 1983, Oxford University Press (OUP)

    Professor Martin O Leach

  462. The spatial resolution of a rotating gamma camera tomographic facility

    Article • British Journal of Radiology, December 1983, Oxford University Press (OUP)

    Professor Martin O Leach

  463. Preliminary clinical images from a prototype positron camera

    Article • British Journal of Radiology, October 1983, Oxford University Press (OUP)

    Professor Martin O Leach

  464. A comparison of attenuation correction methods for quantitative single photon emission computed tomography

    Article • Physics in Medicine and Biology, September 1983, Institute of Physics Publishing

    Professor Martin O Leach

  465. The retention and release of37Ar from samples of human bone examined in vitro and a review of the implications for argon transfer from bone in vivo

    Article • Physics in Medicine and Biology, April 1983, Institute of Physics Publishing

    Professor Martin O Leach

  466. Blood flow measurements and the partition coefficient of 133Xe in bone

    Article • Physics in Medicine and Biology, November 1982, Institute of Physics Publishing

    Professor Martin O Leach

  467. A compartmental model for investigating the influence of physiological factors on the rate of washout of133Xe and37Ar from the body

    Article • Physics in Medicine and Biology, September 1982, Institute of Physics Publishing

    Professor Martin O Leach

  468. The preparation of 37Ar in sterile solution suitable for injection in vivo

    Article • The International Journal of Applied Radiation and Isotopes, July 1982, Elsevier

    Professor Martin O Leach

  469. A rotate–translate CT scanner providing cross‐sectional data suitable for planning the dosimetry of radiotherapy treatment

    Article • Medical Physics, March 1982, Wiley

    Professor Martin O Leach

  470. In vivo measurement of calcium by the 37Ar method: a study of the effect of recirculating breath collection systems on the exhalation rate

    Article • Physics in Medicine and Biology, March 1978, Institute of Physics Publishing

    Professor Martin O Leach

  471. Total body nitrogen measured by the method: A study of the interfering reactions and the variation of spatial sensitivity with depth

    Article • The International Journal of Applied Radiation and Isotopes, March 1977, Elsevier

    Professor Martin O Leach

  472. Batch Fabrication of Micro-Coils for MR Spectroscopy on Silicon

    Article • Institute of Electrical & Electronics Engineers (IEEE)

    Professor Martin O Leach

  473. Does Registration Improve the Performance of a Computer Aided Diagnosis System for Dynamic Contrast-Enhanced MR Mammography?

    Article • Institute of Electrical & Electronics Engineers (IEEE)

    Professor Martin O Leach

  474. A method for the comparison of biomechanical breast models

    Article • Institute of Electrical & Electronics Engineers (IEEE)

    Professor Martin O Leach