All Stories

  1. Bacillus subtilis engineered for topical delivery of an antifungal agent

    Article • PLoS ONE, November 2023, PLOS

    Mark Prausnitz

  2. An ultra-low-cost electroporator with microneedle electrodes (ePatch) for SARS-CoV-2 vaccination

    Article • Proceedings of the National Academy of Sciences, October 2021, Proceedings of the National Academy of Sciences

    Mark Prausnitz

  3. Fabrication of pure-drug microneedles for delivery of montelukast sodium

    Article • Drug Delivery and Translational Research, September 2021, Springer Science + Business Media

    Mark Prausnitz

  4. Thermostability of Measles and Rubella Vaccines in a Microneedle Patch

    Article • Advanced Therapeutics, July 2021, Wiley

    Mark Prausnitz

  5. Efficient Drug Delivery into Skin Using a Biphasic Dissolvable Microneedle Patch with Water‐Insoluble Backing

    Article • Advanced Functional Materials, June 2021, Wiley

    Mark Prausnitz

  6. Serum Protects Cells and Increases Intracellular Delivery of Molecules by Nanoparticle-Mediated Photoporation

    Article • International Journal of Nanomedicine, May 2021, Taylor & Francis

    Mark Prausnitz

  7. Administration of pilocarpine by microneedle patch as a novel method for cystic fibrosis sweat testing

    Article • Bioengineering & Translational Medicine, April 2021, Wiley

    Mark Prausnitz, Dr Lokesh Guglani

  8. Dissolvable Microneedle Patches to Enable Increased Access to Vaccines against SARS-CoV-2 and Future Pandemic Outbreaks

    Article • Vaccines, April 2021, MDPI AG

    Mark Prausnitz

  9. Fabrication of microneedle patches with lyophilized influenza vaccine suspended in organic solvent

    Article • Drug Delivery and Translational Research, February 2021, Springer Science + Business Media

    Mark Prausnitz

  10. Sensitive sensing of biomarkers in interstitial fluid

    Article • Nature Biomedical Engineering, January 2021, Springer Science + Business Media

    Mark Prausnitz

  11. Sampling interstitial fluid from human skin using a microneedle patch

    Article • Science Translational Medicine, November 2020, American Association for the Advancement of Science

    Mark Prausnitz

  12. Relationship between bio-effects and energy transduction during nanoparticle-mediated photoporation

    Article • Journal of Applied Physics, November 2020, American Institute of Physics

    Mark Prausnitz

  13. STAR particles for enhanced topical drug and vaccine delivery

    Article • Nature Reports Stem Cells, March 2020, Springer Science + Business Media

    Mark Prausnitz

  14. Long-acting reversible contraception by effervescent microneedle patch

    Article • Science Advances, November 2019, American Association for the Advancement of Science

    Mark Prausnitz

  15. Microneedle patch drug delivery in the gut

    Article • Nature Reports Stem Cells, October 2019, Springer Science + Business Media

    Mark Prausnitz

  16. Targeting drug delivery within the suprachoroidal space

    Article • Drug Discovery Today, August 2019, Elsevier

    Mark Prausnitz

  17. Extended delivery of vaccines to the skin improves immune responses

    Article • Journal of Controlled Release, June 2019, Elsevier

    Mark Prausnitz

  18. Plasmonic Paper Microneedle Patch for On-Patch Detection of Molecules in Dermal Interstitial Fluid

    Article • ACS Sensors, May 2019, American Chemical Society (ACS)

    Mark Prausnitz

  19. Pharmaceutical jewelry: Earring patch for transdermal delivery of contraceptive hormone

    Article • Journal of Controlled Release, May 2019, Elsevier

    Mark Prausnitz

  20. Co-Delivery of M2e Virus-Like Particles with Influenza Split Vaccine to the Skin Using Microneedles Enhances the Efficacy of Cross Protection

    Article • Pharmaceutics, April 2019, MDPI AG

    Mark Prausnitz

  21. Electrospun Transdermal Patch for Contraceptive Hormone Delivery

    Article • Current Drug Delivery, March 2019, Bentham Science Publishers

    Mark Prausnitz

  22. Monitoring drug pharmacokinetics and immunologic biomarkers in dermal interstitial fluid using a microneedle patch

    Article • Biomedical Microdevices, February 2019, Springer Science + Business Media

    Mark Prausnitz

  23. Rapidly separable microneedle patch for the sustained release of a contraceptive

    Article • Nature Biomedical Engineering, January 2019, Springer Science + Business Media

    Mark Prausnitz

  24. Recruitment and Collection of Dermal Interstitial Fluid Using a Microneedle Patch

    Article • Advanced Healthcare Materials, January 2019, Wiley

    Mark Prausnitz

  25. Development of a thermostable microneedle patch for polio vaccination

    Article • Drug Delivery and Translational Research, December 2018, Springer Science + Business Media

    Mark Prausnitz

  26. Self-healing encapsulation and controlled release of vaccine antigens from PLGA microparticles delivered by microneedle patches

    Article • Bioengineering & Translational Medicine, October 2018, Wiley

    Mark Prausnitz

  27. Vaccination by microneedle patch with inactivated respiratory syncytial virus and monophosphoryl lipid A enhances the protective efficacy and diminishes inflammatory disease after challenge

    Article • PLoS ONE, October 2018, PLOS

    Mark Prausnitz

  28. Hepatitis B vaccination using a dissolvable microneedle patch is immunogenic in mice and rhesus macaques

    Article • Bioengineering & Translational Medicine, August 2018, Wiley

    Mark Prausnitz

  29. Heterosubtypic influenza protection elicited by double-layered polypeptide nanoparticles in mice

    Article • Proceedings of the National Academy of Sciences, July 2018, Proceedings of the National Academy of Sciences

    Mark Prausnitz

  30. Enhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch

    Article • Frontiers in Immunology, July 2018, Frontiers

    Mark Prausnitz

  31. Intradermal immunization by Ebola virus GP subunit vaccines using microneedle patches protects mice against lethal EBOV challenge

    Article • Scientific Reports, July 2018, Springer Science + Business Media

    Mark Prausnitz

  32. Effect of laser fluence, nanoparticle concentration and total energy input per cell on photoporation of cells

    Article • Nanomedicine Nanotechnology Biology and Medicine, July 2018, Elsevier

    Mark Prausnitz

  33. Individually coated microneedles for co-delivery of multiple compounds with different properties

    Article • Drug Delivery and Translational Research, June 2018, Springer Science + Business Media

    Mark Prausnitz

  34. Intradermal Vaccination With Adjuvanted Ebola Virus Soluble Glycoprotein Subunit Vaccine by Microneedle Patches Protects Mice Against Lethal Ebola Virus Challenge

    Article • The Journal of Infectious Diseases, June 2018, Oxford University Press (OUP)

    Mark Prausnitz

  35. Drug delivery using microneedle patches: not just for skin

    Article • Expert Opinion on Drug Delivery, May 2018, Taylor & Francis

    Mark Prausnitz

  36. Ocular drug delivery targeted by iontophoresis in the suprachoroidal space using a microneedle

    Article • Journal of Controlled Release, May 2018, Elsevier

    Mark Prausnitz

  37. A Microneedle Patch for Measles and Rubella Vaccination Is Immunogenic and Protective in Infant Rhesus Macaques

    Article • The Journal of Infectious Diseases, April 2018, Oxford University Press (OUP)

    Mark Prausnitz

  38. Mechanisms of sampling interstitial fluid from skin using a microneedle patch

    Article • Proceedings of the National Academy of Sciences, April 2018, Proceedings of the National Academy of Sciences

    Mark Prausnitz

  39. Stable incorporation of GM-CSF into dissolvable microneedle patch improves skin vaccination against influenza

    Article • Journal of Controlled Release, April 2018, Elsevier

    Mark Prausnitz

  40. Human Suction Blister Fluid Composition Determined Using High-Resolution Metabolomics

    Article • Analytical Chemistry, February 2018, American Chemical Society (ACS)

    Mark Prausnitz

  41. The suprachoroidal space as a route of administration to the posterior segment of the eye

    Article • Advanced Drug Delivery Reviews, February 2018, Elsevier

    Mark Prausnitz

  42. Inactivated rotavirus vaccine by parenteral administration induces mucosal immunity in mice

    Article • Scientific Reports, January 2018, Springer Science + Business Media

    Mark Prausnitz

  43. Photoporation Using Carbon Nanotubes for Intracellular Delivery of Molecules and Its Relationship to Photoacoustic Pressure

    Article • Advanced Healthcare Materials, December 2017, Wiley

    Michael Gray, Mark Prausnitz

  44. Dihydroergotamine mesylate-loaded dissolving microneedle patch made of polyvinylpyrrolidone for management of acute migraine therapy

    Article • Journal of Controlled Release, December 2017, Elsevier

    Mark Prausnitz

  45. Skin immunization by microneedle patch overcomes statin-induced suppression of immune responses to influenza vaccine

    Article • Scientific Reports, December 2017, Springer Science + Business Media

    Mark Prausnitz

  46. Iontophoretic targeting of drug delivery in the eye via the suprachoroidal space

    Article • Acta Ophthalmologica, September 2017, Wiley

    Mark Prausnitz

  47. A boosting skin vaccination with dissolving microneedle patch encapsulating M2e vaccine broadens the protective efficacy of conventional influenza vaccines

    Article • Journal of Controlled Release, September 2017, Elsevier

    Mark Prausnitz

  48. The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial

    Article • The Lancet, August 2017, Elsevier

    Mark Prausnitz

  49. Microneedle patch delivery of influenza vaccine during pregnancy enhances maternal immune responses promoting survival and long-lasting passive immunity to offspring

    Article • Scientific Reports, July 2017, Springer Science + Business Media

    Mark Prausnitz

  50. Role of cytoskeletal mechanics and cell membrane fluidity in the intracellular delivery of molecules mediated by laser‐activated carbon nanoparticles

    Article • Biotechnology and Bioengineering, July 2017, Wiley

    Mark Prausnitz

  51. Engineering Microneedle Patches for Vaccination and Drug Delivery to Skin

    Article • Annual Review of Chemical and Biomolecular Engineering, June 2017, Annual Reviews

    Mark Prausnitz

  52. Tolerability, usability and acceptability of dissolving microneedle patch administration in human subjects

    Article • Biomaterials, June 2017, Elsevier

    Mark Prausnitz

  53. Energy Transfer Mechanisms during Molecular Delivery to Cells by Laser-Activated Carbon Nanoparticles

    Article • Biophysical Journal, March 2017, Elsevier

    Michael Gray, Mark Prausnitz

  54. Challenges and Future Prospects for the Delivery of Biologics: Oral Mucosal, Pulmonary, and Transdermal Routes

    Article • The AAPS Journal, February 2017, Springer Science + Business Media

    Mark Prausnitz

  55. Clearance Kinetics and Clearance Routes of Molecules From the Suprachoroidal Space After Microneedle Injection

    Article • Investigative Ophthalmology & Visual Science, January 2017, Association for Research in Vision and Ophthalmology (ARVO)

    Mark Prausnitz

  56. Thickness and Closure Kinetics of the Suprachoroidal Space Following Microneedle Injection of Liquid Formulations

    Article • Investigative Ophthalmology & Visual Science, January 2017, Association for Research in Vision and Ophthalmology (ARVO)

    Mark Prausnitz

  57. Evaluation of Microneedles in Human Subjects

    Article • January 2017, Springer Science + Business Media

    Mark Prausnitz

  58. Distribution of particles, small molecules and polymeric formulation excipients in the suprachoroidal space after microneedle injection

    Article • Experimental Eye Research, December 2016, Elsevier

    Mark Prausnitz

  59. Targeted Drug Delivery Within the Eye Through the Suprachoroidal Space

    Article • Journal of Ocular Pharmacology and Therapeutics, December 2016, Mary Ann Liebert Inc

    Mark Prausnitz

  60. Ebola Vaccination Using a DNA Vaccine Coated on PLGA-PLL/γPGA Nanoparticles Administered Using a Microneedle Patch

    Article • Advanced Healthcare Materials, November 2016, Wiley

    Mark Prausnitz

  61. Microneedle patches for vaccination in developing countries

    Article • Journal of Controlled Release, October 2016, Elsevier

    Mark Prausnitz

  62. Rabies vaccination in dogs using a dissolving microneedle patch

    Article • Journal of Controlled Release, October 2016, Elsevier

    Mark Prausnitz

  63. Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy

    Article • Journal of Controlled Release, August 2016, Elsevier

    Mark Prausnitz

  64. DNA uptake, intracellular trafficking and gene transfection after ultrasound exposure

    Article • Journal of Controlled Release, July 2016, Elsevier

    Mark Prausnitz

  65. Circumferential flow of particles in the suprachoroidal space is impeded by the posterior ciliary arteries

    Article • Experimental Eye Research, April 2016, Elsevier

    Mark Prausnitz

  66. Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma

    Article • Journal of Controlled Release, April 2016, Elsevier

    Mark Prausnitz

  67. Long-term stability of influenza vaccine in a dissolving microneedle patch

    Article • Drug Delivery and Translational Research, February 2016, Springer Science + Business Media

    Mark Prausnitz

  68. Intracellular delivery of molecules using microfabricated nanoneedle arrays

    Article • Biomedical Microdevices, January 2016, Springer Science + Business Media

    Mark Prausnitz

  69. Enhanced Stability of Inactivated Influenza Vaccine Encapsulated in Dissolving Microneedle Patches

    Article • Pharmaceutical Research, December 2015, Springer Science + Business Media

    Mark Prausnitz

  70. Inkjet printing of transdermal microneedles for the delivery of anticancer agents

    Article • International Journal of Pharmaceutics, October 2015, Elsevier

    Professor Dennis Douroumis, Mark Prausnitz

  71. Enhanced immune responses by skin vaccination with influenza subunit vaccine in young hosts

    Article • Vaccine, September 2015, Elsevier

    Mark Prausnitz

  72. Inactivated polio vaccination using a microneedle patch is immunogenic in the rhesus macaque

    Article • Vaccine, September 2015, Elsevier

    Mark Prausnitz

  73. A microneedle patch containing measles vaccine is immunogenic in non-human primates

    Article • Vaccine, September 2015, Elsevier

    Mark Prausnitz

  74. An economic model assessing the value of microneedle patch delivery of the seasonal influenza vaccine

    Article • Vaccine, September 2015, Elsevier

    Mark Prausnitz

  75. Formulation to target delivery to the ciliary body and choroid via the suprachoroidal space of the eye using microneedles

    Article • European Journal of Pharmaceutics and Biopharmaceutics, September 2015, Elsevier

    Mark Prausnitz

  76. Lidocaine-ibuprofen ionic liquid for dermal anesthesia

    Article • AIChE Journal, August 2015, Wiley

    Mark Prausnitz

  77. Effect of Osmotic Pressure on the Stability of Whole Inactivated Influenza Vaccine for Coating on Microneedles

    Article • PLoS ONE, July 2015, PLOS

    Mark Prausnitz

  78. Microneedle patch delivery to the skin of virus-like particles containing heterologous M2e extracellular domains of influenza virus induces broad heterosubtypic cross-protection

    Article • Journal of Controlled Release, July 2015, Elsevier

    Mark Prausnitz

  79. Delivery of siRNA to ovarian cancer cells using laser-activated carbon nanoparticles

    Article • Nanomedicine, June 2015, Future Medicine

    Mark Prausnitz

  80. Development of a Thermostable Microneedle Patch for Influenza Vaccination

    Article • Journal of Pharmaceutical Sciences, February 2015, Elsevier

    Mark Prausnitz

  81. Microneedle patches: Usability and acceptability for self-vaccination against influenza

    Article • Vaccine, April 2014, Elsevier

    Dr Paula M Frew, Mark Prausnitz

  82. Measles vaccination using a microneedle patch

    Article • Vaccine, July 2013, Elsevier

    Mark Prausnitz

  83. Targeted Drug Delivery to the Eye Enabled by Microneedles

    Article • January 2011, Springer Science + Business Media

    Mark Prausnitz

  84. Delivery Systems for Intradermal Vaccination

    Article • January 2011, Springer Science + Business Media

    Mark Prausnitz

  85. Microneedle-Based Vaccines

    Article • January 2009, Springer Science + Business Media

    Mark Prausnitz

  86. Microneedles for Drug Delivery

    Article • May 2008, Taylor & Francis

    Mark Prausnitz

  87. Microneedles

    Article • November 2005, Taylor & Francis

    Mark Prausnitz

  88. Assessment of Microneedles for Transdermal Drug Delivery

    Article • July 2005, Taylor & Francis

    Mark Prausnitz

  89. Microfabricated Microneedles for Transdermal Drug Delivery

    Article • November 2002, Taylor & Francis

    Mark Prausnitz

  90. Macromolecules as Novel Transdermal Transport Enhancers for Skin Electroporation

    Article • January 1999, Springer Science + Business Media

    Mark Prausnitz

  91. Recent Advances in Skin Electroporation: Mechanism and Efficacy

    Article • January 1999, Springer Science + Business Media

    Mark Prausnitz

  92. The Effects of Pulsed Electrical Protocols on Skin Damage, Sensation, and Pain

    Article • January 1999, Springer Science + Business Media

    Mark Prausnitz

  93. Transdermal Delivery of Macromolecules: Recent Advances by Modification of Skin's Barrier Properties

    Article • July 1997, American Chemical Society (ACS)

    Mark Prausnitz

  94. Electrical Impedance Spectroscopy for Rapid and Noninvasive Analysis of Skin Electroporation

    Article • Springer Science + Business Media

    Mark Prausnitz

  95. Mechanistic Studies of Skin Electroporation Using Biophysical Methods

    Article • Springer Science + Business Media

    Mark Prausnitz