All Stories

  1. Obesity in the global haemophilia population: prevalence, implications and expert opinions for weight management

    Article • Obesity Reviews, September 2018, Wiley

    Dr Margareth Castro Ozelo, Dr Kate Khair

  2. Updates from guardian™: a comprehensive registration programme

    Article • European Journal Of Haematology, December 2015, Wiley

    Dr Margareth Castro Ozelo

  3. Long‐term patterns of safety and efficacy of bleeding prophylaxis with turoctocog alfa (NovoEight ® ) in previously treated patients with severe haemophilia A: interim results of the guardian ™ 2 extensio...

    Article • Haemophilia, June 2015, Wiley

    Dr Margareth Castro Ozelo

  4. Recombinant activated factor VII in the treatment of bleeds and for the prevention of surgery-related bleeding in congenital haemophilia with inhibitors

    Article • Blood Reviews, June 2015, Elsevier

    Dr Margareth Castro Ozelo

  5. Allergic reaction in a cohort of haemophilia A patients using plasma-derived factor VIII (FVIII) concentrate is rare and not necessarily triggered by FVIII

    Article • Haemophilia, April 2015, Wiley

    Dr Margareth Castro Ozelo

  6. A longitudinal evaluation of anti-FVIII antibodies demonstrated IgG4 subclass is mainly correlated with high-titre inhibitor in haemophilia A patients

    Article • Haemophilia, February 2015, Wiley

    Dr Margareth Castro Ozelo

  7. Impact of severe haemophilia A on patients' health status: results from the guardian ™ 1 clinical trial of turoctocog alfa (NovoEight ® )

    Article • Haemophilia, February 2015, Wiley

    Dr Margareth Castro Ozelo

  8. Switching to recombinant factor IX Fc fusion protein prophylaxis results in fewer infusions, decreased factor IX consumption and lower bleeding rates

    Article • British Journal of Haematology, September 2014, Wiley

    Dr Margareth Castro Ozelo

  9. Long‐acting recombinant factor IX Fc fusion protein ( rFIXF c) for perioperative management of subjects with haemophilia B in the phase 3 B‐LONG study

    Article • British Journal of Haematology, September 2014, Wiley

    Dr Margareth Castro Ozelo

  10. Systematic Analysis of Bleeding Phenotype in PT-VWD Compared to Type 2B VWD Using an Electronic Bleeding Questionnaire

    Article • Clinical and Applied Thrombosis/Hemostasis, July 2014, SAGE Publications

    Dr Margareth Castro Ozelo

  11. Safety and efficacy of cryoprecipitate-poor plasma as a replacement fluid for therapeutic plasma exchange in thrombotic thrombocytopenic purpura: A single center retrospective evaluation

    Article • Journal of Clinical Apheresis, June 2014, Wiley

    Dr Margareth Castro Ozelo

  12. Omental implantation of BOECs in hemophilia dogs results in circulating FVIII antigen and a complex immune response

    Article • Blood, May 2014, American Society of Hematology

    Dr Margareth Castro Ozelo

  13. Development of a serious game for children with hemophilia

    Article • May 2014, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Margareth Castro Ozelo

  14. Musculoskeletal evaluation in severe haemophilia A patients from Latin America

    Article • Haemophilia, December 2013, Wiley

    Dr Margareth Castro Ozelo

  15. Phase 3 Study of Recombinant Factor IX Fc Fusion Protein in Hemophilia B

    Article • New England Journal of Medicine, December 2013, New England Journal of Medicine (NEJM/MMS)

    Dr Margareth Castro Ozelo

  16. Increased adhesive and inflammatory properties in blood outgrowth endothelial cells from sickle cell anemia patients

    Article • Microvascular Research, November 2013, Elsevier

    Dr Margareth Castro Ozelo

  17. Results from a large multinational clinical trial (guardian™3) using prophylactic treatment with turoctocog alfa in paediatric patients with severe haemophilia A: safety, efficacy and pharmacokinetics

    Article • Haemophilia, May 2013, Wiley

    Dr Margareth Castro Ozelo

  18. A novel use of thromboelastography in type 2B von Willebrand disease

    Article • International Journal of Laboratory Hematology, April 2013, Wiley

    Dr Margareth Castro Ozelo

  19. Establishing a harmonized haemophilia registry for countries with developing health care systems

    Article • Haemophilia, April 2013, Wiley

    Dr Margareth Castro Ozelo

  20. Surgery in patients with hemophilia: Is thromboprophylaxis mandatory?

    Article • Thrombosis Research, October 2012, Elsevier

    Dr Margareth Castro Ozelo

  21. Factor VIII inhibitors in patients with congenital severe haemophilia A and its relation to genotype

    Article • Haemophilia, August 2012, Wiley

    Dr Margareth Castro Ozelo

  22. Meeting the challenges of haemophilia care and patient support in China and Brazil

    Article • Haemophilia, July 2012, Wiley

    Dr Margareth Castro Ozelo

  23. Non-operative management of blunt major hepatic injury in a young adult with severe haemophilia A

    Article • Haemophilia, February 2012, Wiley

    Dr Margareth Castro Ozelo

  24. Brain plasticity for verbal and visual memories in patients with mesial temporal lobe epilepsy and hippocampal sclerosis: An fMRI study

    Article • Human Brain Mapping, October 2011, Wiley

    Dr Margareth Castro Ozelo

  25. Evaluation of the host response to endotoxemia of FVIII and FIX deficient mice

    Article • Haemophilia, June 2011, Wiley

    Dr Margareth Castro Ozelo

  26. A MicroRNA-regulated and GP64-pseudotyped Lentiviral Vector Mediates Stable Expression of FVIII in a Murine Model of Hemophilia A

    Article • Molecular Therapy, April 2011, Elsevier

    Dr Margareth Castro Ozelo

  27. Frequency of Platelet type versus Type 2B von Willebrand Disease

    Article • Thrombosis and Haemostasis, February 2011, Schattauer GmbH

    Dr Margareth Castro Ozelo

  28. Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy

    Article • Blood, September 2010, American Society of Hematology

    Dr Margareth Castro Ozelo

  29. VKORC1 V66M mutation in African Brazilian patients resistant to oral anticoagulant therapy

    Article • Thrombosis Research, September 2010, Elsevier

    Dr Margareth Castro Ozelo

  30. Long-term prospective study of recurrent venous thromboembolism in a Hispanic population

    Article • Blood Coagulation & Fibrinolysis, September 2010, Wolters Kluwer Health

    Dr Margareth Castro Ozelo

  31. Unique strategies for therapeutic gene transfer in haemophilia A and haemophilia B

    Article • Haemophilia, June 2010, Wiley

    Dr Margareth Castro Ozelo

  32. Simultaneous bleeding and thrombosis in superwarfarin poisoning

    Article • Thrombosis Research, February 2009, Elsevier

    Dr Margareth Castro Ozelo

  33. Reduction of the immune response to factor VIII mediated through tolerogenic factor VIII presentation by immature dendritic cells

    Article • Journal of Thrombosis and Haemostasis, December 2008, Wiley

    Dr Margareth Castro Ozelo

  34. Molecular Genetic Testing of Hemostasis and Thrombosis in Developing Countries: Achievements, Hopes, and Challenges

    Article • Seminars in Thrombosis and Hemostasis, September 2008, Thieme Publishing Group

    Dr Margareth Castro Ozelo

  35. Polymorphisms of methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), methionine synthase reductase (MTRR), and thymidylate synthase (TYMS) in multiple myeloma risk

    Article • Leukemia Research, March 2008, Elsevier

    Dr Margareth Castro Ozelo

  36. Efficacy and safety of dapsone as a second-line treatment in non-splenectomized adults with immune thrombocytopenic purpura

    Article • Platelets, January 2008, Taylor & Francis

    Dr Margareth Castro Ozelo

  37. A cost evaluation of treatment alternatives for mild-to-moderate bleeding episodes in patients with haemophilia and inhibitors in Brazil

    Article • Haemophilia, September 2007, Wiley

    Dr Margareth Castro Ozelo

  38. Association between estrogen receptor alpha and beta gene polymorphisms and deep vein thrombosis

    Article • Thrombosis Research, January 2007, Elsevier

    Dr Margareth Castro Ozelo

  39. Evidence of Multiyear Factor IX Expression by AAV-Mediated Gene Transfer to Skeletal Muscle in an Individual with Severe Hemophilia B

    Article • Molecular Therapy, September 2006, Elsevier

    Dr Margareth Castro Ozelo

  40. An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis

    Article • Nature Genetics, June 2006, Springer Science + Business Media

    Dr Margareth Castro Ozelo

  41. Early in vivo anticoagulation inhibits the angiogenic response following hindlimb ischemia in a rodent model

    Article • Thrombosis and Haemostasis, June 2006, Schattauer GmbH

    Dr Margareth Castro Ozelo

  42. Clinical Impact of Oral Health Indexes in Dental Extraction of Hemophilic Patients

    Article • Journal of Oral and Maxillofacial Surgery, May 2006, Elsevier

    Dr Margareth Castro Ozelo

  43. Erratum: CORRIGENDUM: Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

    Article • Nature Reports Stem Cells, May 2006, Springer Science + Business Media

    Dr Margareth Castro Ozelo

  44. Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

    Article • Nature Reports Stem Cells, February 2006, Springer Science + Business Media

    Dr Margareth Castro Ozelo

  45. Use of recombinant factor VIIa in the management of severe bleeding episodes in patients with Bernard–Soulier syndrome

    Article • Annals of Hematology, November 2005, Springer Science + Business Media

    Dr Margareth Castro Ozelo

  46. What is a cure and how do we get there?

    Article • Haemophilia, October 2004, Wiley

    Dr Margareth Castro Ozelo

  47. Genetic variability of platelet glycoprotein Ibα gene

    Article • American Journal of Hematology, September 2004, Wiley

    Dr Margareth Castro Ozelo

  48. Platelet glycoprotein Ibα polymorphisms modulate the risk for myocardial infarction

    Article • Thrombosis and Haemostasis, July 2004, Schattauer GmbH

    Dr Margareth Castro Ozelo

  49. Effects of high platelet concentration in collecting and freezing dry platelets concentrates

    Article • Transfusion and Apheresis Science, June 2004, Elsevier

    Dr Margareth Castro Ozelo

  50. Rapid detection of the prothrombin C20209T variant by differential sensitivity to restriction endonuclease digestion

    Article • Journal of Thrombosis and Haemostasis, December 2003, Wiley

    Dr Margareth Castro Ozelo

  51. AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B

    Article • Blood, April 2003, American Society of Hematology

    Dr Margareth Castro Ozelo

  52. The impact of the search for thrombophilia risk factors among antiphospholipid syndrome patients with thrombosis

    Article • Blood Coagulation & Fibrinolysis, October 2000, Wolters Kluwer Health

    Dr Margareth Castro Ozelo

  53. Possible Association between Cytomegalovirus Infection and Gastrointestinal Bleeding in Hemophiliac Patients

    Article • Acta Haematologica, January 2000, Karger Publishers

    Dr Margareth Castro Ozelo

  54. Inherited Risk Factors for Thrombophilia Among Children with Legg-Calvé-Perthes Disease

    Article • Journal of Pediatric Orthopaedics, January 1999, Wolters Kluwer Health

    Dr Margareth Castro Ozelo

  55. 82 Megakaryopoiesis in myelodysplastic syndromes: Morphological and immunocytochemical features

    Article • Leukemia Research, April 1997, Elsevier

    Dr Margareth Castro Ozelo