All Stories

  1. Benchmarking antibody clustering methods using sequence, structural, and machine learning similarity measures for antibody discovery applications

    Article • Frontiers in Molecular Biosciences, March 2024, Frontiers

    PhD Marek Orlowski

  2. LAP: Liability Antibody Profiler by sequence & structural mapping of natural and therapeutic antibodies

    Article • PLoS Computational Biology, March 2024, PLOS

    PhD Marek Orlowski

  3. Rola kluczowych hormonów i ich receptorów w rozwoju owadów na przykładzie Drosophila melanogaster i Aedes aegypti

    Article • Kosmos, December 2022, Uniwersytet Mikolaja Kopernika/Nicolaus Copernicus University

    PhD Marek Orlowski

  4. Metal Ions Induce Liquid Condensate Formation by the F Domain of Aedes aegypti Ecdysteroid Receptor. New Perspectives of Nuclear Receptor Studies

    Article • Cells, March 2021, MDPI AG

    PhD Marek Orlowski

  5. Nuclear immunophilin FKBP39 from Drosophila melanogaster drives spontaneous liquid-liquid phase separation

    Article • International Journal of Biological Macromolecules, November 2020, Elsevier

    PhD Marek Orlowski

  6. Copper(II)-Binding Induces a Unique Polyproline Type II Helical Structure within the Ion-Binding Segment in the Intrinsically Disordered F-Domain of Ecdysteroid Receptor from Aedes aegypti

    Article • Inorganic Chemistry, August 2019, American Chemical Society (ACS)

    PhD Marek Orlowski

  7. The intrinsically disordered C-terminal F domain of the ecdysteroid receptor from Aedes aegypti exhibits metal ion-binding ability

    Article • The Journal of Steroid Biochemistry and Molecular Biology, February 2019, Elsevier

    PhD Marek Orlowski

  8. Intrinsically disordered N-terminal domain of the Helicoverpa armigera Ultraspiracle stabilizes the dimeric form via a scorpion-like structure

    Article • The Journal of Steroid Biochemistry and Molecular Biology, October 2018, Elsevier

    PhD Marek Orlowski

  9. Molecular determinants of FKBP39 subcellular distribution.

    Article • Biological Chemistry, January 2018, De Gruyter

    PhD Marek Orlowski, Jurek Dobrucki

  10. Homodimerization propensity of the intrinsically disordered N-terminal domain of Ultraspiracle from Aedes aegypti

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, June 2014, Elsevier

    PhD Marek Orlowski

  11. The Molecular Basis of Conformational Instability of the Ecdysone Receptor DNA Binding Domain Studied by In Silico and In Vitro Experiments

    Article • PLOS One, January 2014, PLOS

    PhD Marek Orlowski

  12. Multidomain sumoylation of the ecdysone receptor (EcR) from Drosophila melanogaster

    Article • The Journal of Steroid Biochemistry and Molecular Biology, November 2013, Elsevier

    PhD Marek Orlowski

  13. Conformational changes in the DNA-binding domains of the ecdysteroid receptor during the formation of a complex with the hsp27 response element

    Article • Journal of Biomolecular Structure and Dynamics, June 2012, Taylor & Francis

    PhD Marek Orlowski

  14. The composite nature of the interaction between nuclear receptors EcR and DHR38

    Article • Biological Chemistry, June 2012, De Gruyter

    Jurek Dobrucki, PhD Marek Orlowski

  15. Sequences that direct subcellular traffic of the Drosophila methoprene-tolerant protein (MET) are located predominantly in the PAS domains

    Article • Molecular and Cellular Endocrinology, October 2011, Elsevier

    Jurek Dobrucki, PhD Marek Orlowski

  16. The variety of complexes formed by EcR and Usp nuclear receptors in the nuclei of living cells

    Article • Molecular and Cellular Endocrinology, November 2008, Elsevier

    Jurek Dobrucki, PhD Marek Orlowski

  17. Regulatory elements in the juvenile hormone binding protein gene from Galleria mellonella — Topography of binding sites for Usp and EcRDBD

    Article • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, June 2008, Elsevier

    PhD Marek Orlowski

  18. Novel DNA-binding element within the C-terminal extension of the nuclear receptor DNA-binding domain

    Article • Nucleic Acids Research, April 2007, Oxford University Press (OUP)

    PhD Marek Orlowski

  19. EcR and Usp, components of the ecdysteroid nuclear receptor complex, exhibit differential distribution of molecular determinants directing subcellular trafficking

    Article • Cellular Signalling, March 2007, Elsevier

    Jurek Dobrucki, PhD Marek Orlowski

  20. The DNA-Binding Domain of the Ultraspiracle Drives Deformation of the Response Element Whereas the DNA-Binding Domain of the Ecdysone Receptor Is Responsible for a Slight Additional Change of the Preformed Structure

    Article • Biochemistry, December 2005, American Chemical Society (ACS)

    PhD Marek Orlowski

  21. Plasticity of the Ecdysone Receptor DNA Binding Domain

    Article • Molecular Endocrinology, September 2004, Endocrine Society

    PhD Marek Orlowski