All Stories

  1. Analysis of Biologics Molecular Descriptors towards Predictive Modelling for Protein Drug Development Using Time-Gated Raman Spectroscopy

    Article • Pharmaceutics, August 2022, MDPI AG

    Marco Casteleijn

  2. Characterization, Stability, and In Vivo Efficacy Studies of Recombinant Human CNTF and Its Permeation into the Neural Retina in Ex Vivo Organotypic Retinal Explant Culture Models

    Article • Pharmaceutics, June 2020, MDPI AG

    Marco Casteleijn

  3. Assessment of recombinant protein production in E. coli with Time-Gated Surface Enhanced Raman Spectroscopy (TG-SERS)

    Article • Scientific Reports, February 2020, Springer Science + Business Media

    Marco Casteleijn

  4. CD44 aptamer mediated cargo delivery to lysosomes of retinal pigment epithelial cells to prevent age-related macular degeneration

    Article • Biochemistry and Biophysics Reports, July 2019, Elsevier

    Marco Casteleijn

  5. Accelerated pharmaceutical protein development with integrated cell free expression, purification, and bioconjugation

    Article • Scientific Reports, August 2018, Springer Science + Business Media

    Marco Casteleijn

  6. Interaction of lecithin:cholesterol acyltransferase with lipid surfaces and apolipoprotein A-I-derived peptides

    Article • Journal of Lipid Research, February 2018, American Society for Biochemistry & Molecular Biology (ASBMB)

    Marco Casteleijn

  7. Spin coated chitin films for biosensors and its analysis are dependent on chitin-surface interactions

    Article • Colloids and Surfaces A Physicochemical and Engineering Aspects, February 2018, Elsevier

    Marco Casteleijn

  8. Pharmacokinetic aspects of retinal drug delivery

    Article • Progress in Retinal and Eye Research, March 2017, Elsevier

    Marco Casteleijn

  9. Application of aptamers in diagnostics, drug-delivery and imaging

    Article • Journal of Biosciences, August 2016, Springer Science + Business Media

    Marco Casteleijn

  10. Expression without boundaries: Cell-free protein synthesis in pharmaceutical research

    Article • International Journal of Pharmaceutics, January 2013, Elsevier

    Marco Casteleijn

  11. High-temperature cultivation and 5′ mRNA optimization are key factors for the efficient overexpression of thermostable Deinococcus geothermalis purine nucleoside phosphorylase in Escherichia coli

    Article • Journal of Biotechnology, December 2011, Elsevier

    Marco Casteleijn

  12. Optimization of soluble expression of recombinant thermophilic nucleoside phosphorylases

    Article • Journal of Biotechnology, November 2010, Elsevier

    Marco Casteleijn

  13. Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase

    Article • Acta Crystallographica Section D Biological Crystallography, July 2010, International Union of Crystallography

    Marco Casteleijn

  14. CRYSTALLOGRAPHIC BINDING STUDIES WITH AN ENGINEERED MONOMERIC VARIANT OF TRIOSEPHOSPHATE ISOMERASE

    Article • January 2010, Protein Data Bank, Rutgers University

    Marco Casteleijn

  15. Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase

    Article • January 2010, Protein Data Bank, Rutgers University

    Marco Casteleijn

  16. Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase

    Article • January 2010, Protein Data Bank, Rutgers University

    Marco Casteleijn

  17. Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase

    Article • January 2010, Protein Data Bank, Rutgers University

    Marco Casteleijn

  18. Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase

    Article • January 2010, Protein Data Bank, Rutgers University

    Marco Casteleijn

  19. Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase

    Article • December 2009, Protein Data Bank, Rutgers University

    Marco Casteleijn

  20. Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase

    Article • December 2009, Protein Data Bank, Rutgers University

    Marco Casteleijn

  21. EnBase™: Novel high-cell-density-culture based screening platform

    Article • Chemie Ingenieur Technik, August 2009, Wiley

    Marco Casteleijn

  22. Enzyme controlled glucose auto-delivery for high cell density cultivations in microplates and shake flasks

    Article • Microbial Cell Factories, November 2008, Springer Science + Business Media

    Marco Casteleijn

  23. The A178L mutation in the C-terminal hinge of the flexible loop-6 of triosephosphate isomerase (TIM) induces a more closed conformation of this hinge region in dimeric and monomeric TIM

    Article • February 2008, Protein Data Bank, Rutgers University

    Marco Casteleijn

  24. Structure-based protein engineering efforts with a monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties

    Article • Protein Engineering Design and Selection, January 2008, Oxford University Press (OUP)

    Marco Casteleijn

  25. Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM

    Article • Acta Crystallographica Section D Biological Crystallography, January 2008, International Union of Crystallography

    Marco Casteleijn

  26. Controlled high-cell density cultivation in shake flasks

    Article • Journal of Biotechnology, September 2007, Elsevier

    Marco Casteleijn

  27. Protein engineering of non-natural enzymes

    Article • Journal of Biotechnology, September 2007, Elsevier

    Marco Casteleijn

  28. Creating new enzymes—From triosephosphate isomerase to kealases

    Article • Journal of Biotechnology, September 2007, Elsevier

    Marco Casteleijn

  29. High-cell density cultivation technique for microplates

    Article • Journal of Biotechnology, September 2007, Elsevier

    Marco Casteleijn

  30. The functional role of the conserved active site proline of triosephosphate isomerase

    Article • January 2007, Protein Data Bank, Rutgers University

    Marco Casteleijn

  31. The functional role of the conserved active site proline of triosephosphate isomerase

    Article • January 2007, Protein Data Bank, Rutgers University

    Marco Casteleijn

  32. Functional Role of the Conserved Active Site Proline of Triosephosphate Isomerase,

    Article • Biochemistry, December 2006, American Chemical Society (ACS)

    Marco Casteleijn

  33. Physicochemical studies on the stability of influenza haemagglutinin in vaccine bulk material

    Article • European Journal of Pharmaceutical Sciences, September 2004, Elsevier

    Marco Casteleijn