All Stories

  1. Single cell analysis of human nickel allergy
  2. MEK inhibitor resistance by ERK5 in NRAS-driven melanoma
  3. Stress and STAT1 signaling in Hidradenitis suppurativa
  4. Interaction of transcription factor FoxO3 with histone acetyltransferase complex subunit TRRAP Modulates Gene Expression and Apoptosis
  5. The MEK5/ERK5 Pathway in Health and Disease
  6. Efficient suppression of NRAS-driven melanoma by co-inhibition of ERK1/2 and ERK5 MAPK pathways
  7. Improved metal allergen reactivity of artificial skin models by integration of TLR4‐positive cells
  8. Altered NOX expression does not seem to account for epidermal NLRP3 inflammasome activation in Hidradenitis Suppurativa
  9. Human “TH9” cells are a subpopulation of PPAR-γ+ TH2 cells
  10. Activation of ERK5 by bisphosphonates
  11. Innate Immune System Response in Metal Allergy: Toll-Like Receptors
  12. Potent NLRP3 inflammasome activation by the HIV reverse-transcriptase inhibitor abacavir
  13. Allergy-inducing chromium compounds trigger potent innate immune stimulation via ROS-dependent inflammasome activation
  14. Methods to Investigate the Role of Toll-Like Receptors in Allergic Contact Dermatitis
  15. Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa
  16. Serine 220 phosphorylation of the Merkel cell polyomavirus large T antigen crucially supports growth of Merkel cell carcinoma cells
  17. Endothelial-to-mesenchymal transition contributes to fibro-proliferative vascular disease and is modulated by fluid shear stress
  18. Immunology of metal allergies
  19. PAK1 repression via the MEK5/Erk5/KLF2 axis
  20. Metal allergens nickel and cobalt facilitate TLR4 homodimerization independently of MD2
  21. Inhibition of VCAM-1 expression in endothelial cells by CORM-3: The role of the ubiquitin–proteasome system, p38, and mitochondrial respiration
  22. Animal models for nickel allergy
  23. Nickel allergies: paying the Toll for innate immunity
  24. Mechanisms of chemical-induced innate immunity in allergic contact dermatitis
  25. Neues zur Pathophysiologie des allergischen Kontaktekzems auf Nickel
  26. Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel
  27. Erk5 Activation Elicits a Vasoprotective Endothelial Phenotype via Induction of Kruppel-like Factor 4 (KLF4)
  28. The contact allergen nickel sensitizes primary human endothelial cells and keratinocytes to TRAIL‐mediated apoptosis
  29. FOXO3 Modulates Endothelial Gene Expression and Function by Classical and Alternative Mechanisms
  30. MEK5/ERK5 Signaling Modulates Endothelial Cell Migration and Focal Contact Turnover
  31. The carbon monoxide releasing molecule (CORM‐3) inhibits expression of vascular cell adhesion molecule‐1 and E‐selectin independently of haem oxygenase‐1 expression
  32. Lack of T-Cell Receptor-Induced Signaling Is Crucial for CD95 Ligand Up-regulation and Protects Cutaneous T-Cell Lymphoma Cells from Activation-Induced Cell Death
  33. Candida albicans Triggers Activation of Distinct Signaling Pathways to Establish a Proinflammatory Gene Expression Program in Primary Human Endothelial Cells
  34. The Contact Allergen Nickel Triggers a Unique Inflammatory and Proangiogenic Gene Expression Pattern via Activation of NF- B and Hypoxia-Inducible Factor-1 
  35. Elevated serum levels of calcium-binding S100 proteins A8 and A9 reflect disease activity and abnormal differentiation of keratinocytes in psoriasis
  36. Exploiting the Compromised Spindle Assembly Checkpoint Function of Tumor Cells: Dawn on the Horizon?
  37. Ablation of the spindle assembly checkpoint by a compound targeting Mps1
  38. Cell Cycle Inhibition by FoxO Forkhead Transcription Factors Involves Downregulation of Cyclin D
  39. Selective Expression of Calcium-Binding Proteins S100A8 and S100A9 at Distinct Sites of Hair Follicles
  40. Ras-independent Activation of the Raf/MEK/ERK Pathway upon Calcium-induced Differentiation of Keratinocytes
  41. In vivo functional analysis of the Daughter of Sevenless protein in receptor tyrosine kinase signaling