All Stories

  1. Tg.rasH2 Mice and not CByB6F1 Mice Should Be Used for 28-Day Dose Range Finding Studies Prior to 26-Week Tg.rasH2 Carcinogenicity Studies
  2. Exudative Inflammatory Lesions in the Nasal Cavities of the 26-Week Tg.rasH2 Mice Oral Gavage Carcinogenicity Studies
  3. Vascular proliferation on serosa of uterus in Tg.rasH2 mice can progress to hemangiosarcoma.
  4. Renal Tumors in 26-Week Tg.Rash2 Mice Carcinogenicity Studies
  5. Recommendations to eliminate high doses set at MTD in Tg.rasH2 carcinogenicity studies.
  6. Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron X-ray fluorescence microscopy
  7. Carcinogenicity assessment of the pan-caspase inhibitor, emricasan, in Tg.rasH2 mice
  8. Combination comet/micronucleus assay validation performed by BioReliance under the JaCVAM initiative
  9. Regulatory Forum Opinion Piece*
  10. Trend Analysis of Body Weight Parameters, Mortality, and Incidence of Spontaneous Tumors in Tg.rasH2 Mice
  11. Relationship of Body Weight Parameters with the Incidence of Common Spontaneous Tumors in Tg.rasH2 Mice
  12. The 26-Week Tg.Rash2 Mice Carcinogenicity Studies
  13. Incidence of Spontaneous Non-Neoplastic Lesions in Transgenic CBYB6F1-Tg(HRAS)2Jic Mice
  14. Historical Control Data of Spontaneous Tumors in Transgenic CByB6F1-Tg(HRAS)2Jic (Tg.rasH2) Mice
  15. Reduction in the Number of Animals and the Evaluation Period for the Positive Control Group in Tg.rasH2 Short-Term Carcinogenicity Studies
  16. Genotoxic assessment and toxicity evaluation of peginesatide in CByB6F1 hybrid mice
  17. Immunohistochemical and Clinical Evaluation of p53 in Canine Cutaneous Mast Cell Tumors
  18. Fluorosis in a Wild Cotton Rat (Sigmodon hispidus) Population Inhabiting a Petrochemical Waste Site
  19. Spontaneous Altered Hepatocellular Foci (AHF) in Captive Aged Male Cotton Rats (Sigmodon hispidus)