All Stories

  1. Cellular Uptake and Phototoxicity Optimization of Arene Ruthenium Porphyrin Derivatives

    Article • Inorganics, March 2024, MDPI AG

    Professor Ludmil T Benov

  2. Antibacterial Activity of Synthetic Cationic Iron Porphyrins

    Article • Antioxidants, October 2020, MDPI AG

    Professor Ludmil T Benov

  3. Effect of growth media on the MTT colorimetric assay in bacteria

    Article • PLOS One, August 2019, PLOS

    Professor Ludmil T Benov

  4. Sublethal Photodynamic Treatment Does Not Lead to Development of Resistance

    Article • Frontiers in Microbiology, July 2018, Frontiers

    Professor Ludmil T Benov

  5. Post-illumination cellular effects of photodynamic treatment

    Article • PLOS One, December 2017, PLOS

    Professor Ludmil T Benov

  6. Neuroprotective effect of green tea following crush nerve injury.

    Article • Journal of Neurosurgery Spine, November 2017, Journal of Neurosurgery Publishing Group (JNSPG)

    Waleed Renno, Professor Ludmil T Benov

  7. The Contribution of Superoxide Radical to Cadmium Toxicity in E. coli

    Article • Biological Trace Element Research, May 2017, Springer Science + Business Media

    Professor Ludmil T Benov

  8. Optimizing Zn porphyrin-based photosensitizers for efficient antibacterial photodynamic therapy

    Article • Photodiagnosis and Photodynamic Therapy, March 2017, Elsevier

    Professor Ludmil T Benov

  9. Cationic amphiphilic Zn-porphyrin with high antifungal photodynamic potency

    Article • Photochemical & Photobiological Sciences, January 2017, Springer Science + Business Media

    Professor Ludmil T Benov

  10. Important cellular targets for antimicrobial photodynamic therapy

    Article • Applied Microbiology and Biotechnology, May 2016, Springer Science + Business Media

    Professor Ludmil T Benov

  11. Is there a role for neurotrophic factors and their receptors in augmenting the neuroprotective effect of (−)-epigallocatechin-3-gallate treatment of sciatic nerve crush injury?

    Article • Neuropharmacology, March 2016, Elsevier

    Professor Ludmil T Benov

  12. Synthesis and biological evaluation of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives

    Article • European Journal of Medicinal Chemistry, December 2015, Elsevier

    Professor Oludotun A. Phillips, Professor Ludmil T Benov

  13. Anticancer therapeutic potential of Mn porphyrin/ascorbate system

    Article • Free Radical Biology and Medicine, December 2015, Elsevier

    Professor Ludmil T Benov

  14. A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics

    Article • Free Radical Biology and Medicine, September 2015, Elsevier

    Professor Ludmil T Benov

  15. Amphiphilic cationic Zn-porphyrins with high photodynamic antimicrobial activity

    Article • Future Microbiology, May 2015, Future Medicine

    Professor Ludmil T Benov

  16. Evaluation of the monoamine oxidases inhibitory activity of a small series of 5-(azole)methyl oxazolidinones

    Article • European Journal of Pharmaceutical Sciences, April 2015, Elsevier

    Professor Oludotun A. Phillips, Professor Ludmil T Benov

  17. Photodynamic Therapy: Current Status and Future Directions

    Article • Medical Principles and Practice, January 2015, Karger Publishers

    Professor Ludmil T Benov

  18. Rational Design of Superoxide Dismutase (SOD) Mimics: The Evaluation of the Therapeutic Potential of New Cationic Mn Porphyrins with Linear and Cyclic Substituents

    Article • Inorganic Chemistry, October 2014, American Chemical Society (ACS)

    Professor Ludmil T Benov

  19. Targeting Mitochondria by Zn(II)N-Alkylpyridylporphyrins: The Impact of Compound Sub-Mitochondrial Partition on Cell Respiration and Overall Photodynamic Efficacy

    Article • PLOS One, September 2014, PLOS

    Professor Ludmil T Benov

  20. Simple Biological Systems for Assessing the Activity of Superoxide Dismutase Mimics

    Article • Antioxidants & Redox Signaling, May 2014, Mary Ann Liebert Inc

    Professor Ludmil T Benov

  21. Effect of Molecular Characteristics on Cellular Uptake, Subcellular Localization, and Phototoxicity of Zn(II)N-Alkylpyridylporphyrins

    Article • Journal of Biological Chemistry, November 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Ludmil T Benov

  22. Differential Coordination Demands in Fe versus Mn Water-Soluble Cationic Metalloporphyrins Translate into Remarkably Different Aqueous Redox Chemistry and Biology

    Article • Inorganic Chemistry, May 2013, American Chemical Society (ACS)

    Professor Ludmil T Benov

  23. Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications

    Article • Redox Biology, January 2013, Elsevier

    Professor Ludmil T Benov

  24. A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity

    Article • Free Radical Biology and Medicine, May 2012, Elsevier

    Professor Ludmil T Benov

  25. Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

    Article • Free Radical Biology and Medicine, September 2011, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Professor Ludmil T Benov

  26. Cell-based bioassay for compounds with prooxidant activity

    Article • July 2011, WITPRESS LTD.

    Professor Ludmil T Benov

  27. A Combination of Two Antioxidants (An SOD Mimic and Ascorbate) Produces a Pro-Oxidative Effect Forcing Escherichia coli to Adapt Via Induction of oxyR Regulon

    Article • Anti-Cancer Agents in Medicinal Chemistry, May 2011, Bentham Science Publishers

    Professor Ludmil T Benov

  28. The Potential of Zn(II) N-Alkylpyridylporphyrins for Anticancer Therapy

    Article • Anti-Cancer Agents in Medicinal Chemistry, February 2011, Bentham Science Publishers

    Professor Ludmil T Benov

  29. Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(iii) N-methoxyalkylpyridylporphyrins

    Article • Dalton Transactions, January 2011, Royal Society of Chemistry

    Professor Ludmil T Benov

  30. Comments on ‘The Effect of Training Type on Oxidative DNA Damage and Antioxidant Capacity during Three-Dimensional Space Exercise’

    Article • Medical Principles and Practice, January 2011, Karger Publishers

    Professor Ludmil T Benov

  31. Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site

    Article • Free Radical Research, October 2010, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong, Professor Ludmil T Benov

  32. Protein damage by photo-activated Zn(II) N-alkylpyridylporphyrins

    Article • Amino Acids, June 2010, Springer Science + Business Media

    Professor Ludmil T Benov

  33. High Lipophilicity of meta Mn(III)N-Alkylpyridylporphyrin-Based Superoxide Dismutase Mimics Compensates for Their Lower Antioxidant Potency and Makes Them as Effective as Ortho Analogues in Protecting Superoxide Dismutase-DeficientEscherichia coli

    Article • Journal of Medicinal Chemistry, December 2009, American Chemical Society (ACS)

    Professor Ludmil T Benov

  34. Effect of potent redox-modulating manganese porphyrin, MnTM-2-PyP, on the Na+/H+exchangers NHE-1 and NHE-3 in the diabetic rat

    Article • Redox Report, December 2009, Taylor & Francis

    Professor Ludmil T Benov

  35. ON THE HEAVY METAL COMPOUNDS HEMOLYTIC ACTION

    Article • Acta Pharmacologica et Toxicologica, March 2009, Wiley

    Professor Ludmil T Benov

  36. SOME INVESTIGATIONS ON THE Zn(II)-RED BLOOD CELL INTERACTION

    Article • Acta Pharmacologica et Toxicologica, March 2009, Wiley

    Professor Ludmil T Benov

  37. Pure MnTBAP selectively scavenges peroxynitrite over superoxide: Comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy

    Article • Free Radical Biology and Medicine, January 2009, Elsevier

    Professor Ludmil T Benov

  38. SOD-like activity of Mn(II) β-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)porphyrin equals that of the enzyme itself

    Article • Archives of Biochemistry and Biophysics, September 2008, Elsevier

    Professor Ludmil T Benov

  39. Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: Protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier

    Article • Free Radical Biology and Medicine, July 2008, Elsevier

    Professor Ludmil T Benov

  40. Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: The effect of charge distribution

    Article • Dalton Transactions, January 2008, Royal Society of Chemistry

    Professor Ludmil T Benov

  41. An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation

    Article • Free Radical Research, January 2008, Taylor & Francis

    Professor Ludmil T Benov

  42. Inactivation of metabolic enzymes by photo-treatment with zinc meta N-methylpyridylporphyrin

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, November 2007, Elsevier

    Professor Ludmil T Benov

  43. Induction of oxidative cell damage by photo-treatment with zincmetaN-methylpyridylporphyrin

    Article • Free Radical Research, January 2007, Taylor & Francis

    Professor Ludmil T Benov

  44. Glycolaldehyde induces growth inhibition and oxidative stress in human breast cancer cells*

    Article • Free Radical Biology and Medicine, April 2006, Elsevier

    Professor Ludmil T Benov

  45. Photosensitizing action of isomeric zincN-methylpyridylporphyrins in human carcinoma cells

    Article • Free Radical Research, January 2006, Taylor & Francis

    Professor Ludmil T Benov

  46. A Manganese porphyrin suppresses oxidative stress and extends the life span of streptozotocin-diabetic rats

    Article • Free Radical Research, January 2005, Taylor & Francis

    Professor Ludmil T Benov

  47. Escherichia coliΔfurmutant displays low HPII catalase activity in stationary phase

    Article • Redox Report, December 2003, Taylor & Francis

    Professor Ludmil T Benov

  48. Glycolaldehyde induces apoptosis in a human breast cancer cell line

    Article • Archives of Biochemistry and Biophysics, September 2003, Elsevier

    Professor Ludmil T Benov

  49. Triosephosphates are toxic to superoxide dismutase-deficient Escherichia coli

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, July 2003, Elsevier

    Professor Ludmil T Benov

  50. Superoxide-dependence of the short chain sugars-induced mutagenesis

    Article • Free Radical Biology and Medicine, February 2003, Elsevier

    Professor Ludmil T Benov

  51. Induction of the soxRS regulon of Escherichia coli by glycolaldehyde

    Article • Archives of Biochemistry and Biophysics, November 2002, Elsevier

    Professor Ludmil T Benov

  52. Is reduction of the sulfonated tetrazolium 2,3-bis (2-methoxy-4-nitro-5-sulfophenyl)-2-tetrazolium 5-carboxanilide a reliable measure of intracellular superoxide production?

    Article • Analytical Biochemistry, November 2002, Elsevier

    Professor Ludmil T Benov

  53. Disrupting Escherichia coli: A Comparison of Methods

    Article • BMB Reports, July 2002, Korean Society for Biochemistry and Molecular Biology - BMB Reports

    Professor Ludmil T Benov

  54. Manganese supplementation relieves the phenotypic deficits seen in superoxide-dismutase-null Escherichia coli

    Article • Archives of Biochemistry and Biophysics, June 2002, Elsevier

    Professor Ludmil T Benov

  55. Isomeric N-alkylpyridylporphyrins and their Zn(II) complexes: inactive as SOD mimics but powerful photosensitizers

    Article • Archives of Biochemistry and Biophysics, June 2002, Elsevier

    Professor Ludmil T Benov

  56. Polyphosphate accumulation and oxidative DNA damage in superoxide dismutase-deficient Escherichia coli

    Article • Free Radical Biology and Medicine, December 2001, Elsevier

    Professor Ludmil T Benov

  57. How superoxide radical damages the cell

    Article • PROTOPLASMA, March 2001, Springer Science + Business Media

    Professor Ludmil T Benov

  58. Glycerol metabolism in superoxide dismutase-deficientEscherichia coli

    Article • Free Radical Research, January 2001, Taylor & Francis

    Professor Ludmil T Benov

  59. An Anionic Impurity in Preparations of Cytochrome c Interferes with Assays of Cationic Catalysts of the Dismutation of the Superoxide Anion Radical

    Article • Analytical Biochemistry, November 1999, Elsevier

    Professor Ludmil T Benov

  60. Induction of thesoxRS Regulon ofEscherichia coliby Superoxide

    Article • Journal of Biological Chemistry, April 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Ludmil T Benov

  61. Why Superoxide Imposes an Aromatic Amino Acid Auxotrophy onEscherichia coli

    Article • Journal of Biological Chemistry, February 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Ludmil T Benov

  62. Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical

    Article • Free Radical Biology and Medicine, November 1998, Elsevier

    Professor Ludmil T Benov

  63. Superoxide Dependence of the Toxicity of Short Chain Sugars

    Article • Journal of Biological Chemistry, October 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Ludmil T Benov

  64. TheOrthoEffect Makes Manganese(III)Meso-Tetrakis(N-Methylpyridinium-2-yl)Porphyrin a Powerful and Potentially Useful Superoxide Dismutase Mimic

    Article • Journal of Biological Chemistry, September 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Ludmil T Benov

  65. Growth in Iron-enriched Medium Partially CompensatesEscherichia colifor the Lack of Manganese and Iron Superoxide Dismutase

    Article • Journal of Biological Chemistry, April 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Ludmil T Benov

  66. Superoxide Imposes Leakage of Sulfite fromEscherichia coli

    Article • Archives of Biochemistry and Biophysics, November 1997, Elsevier

    Professor Ludmil T Benov

  67. The Copper- and Zinc-Containing Superoxide Dismutase fromEscherichia coli:Molecular Weight and Stability

    Article • Archives of Biochemistry and Biophysics, April 1997, Elsevier

    Professor Ludmil T Benov

  68. The rate of adaptive mutagenesis in Escherichia coli is enhanced by oxygen (superoxide)

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, October 1996, Elsevier

    Professor Ludmil T Benov

  69. The Mechanism of the Auxotrophy for Sulfur-containing Amino Acids Imposed uponEscherichia coliby Superoxide

    Article • Journal of Biological Chemistry, August 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Ludmil T Benov

  70. Escherichia coli exhibits negative chemotaxis in gradients of hydrogen peroxide, hypochlorite, and N-chlorotaurine: products of the respiratory burst of phagocytic cells.

    Article • Proceedings of the National Academy of Sciences, May 1996, Proceedings of the National Academy of Sciences

    Professor Ludmil T Benov

  71. Functional Significance of the Cu,ZnSOD inEscherichia coli

    Article • Archives of Biochemistry and Biophysics, March 1996, Elsevier

    Professor Ludmil T Benov

  72. Purification and characterization of the Cu,Zn SOD from Escherichia coli

    Article • Free Radical Biology and Medicine, January 1996, Elsevier

    Professor Ludmil T Benov

  73. A Superoxide-Dismutase Mimic Protects SodA SodB Escherichia coli against Aerobic Heating and Stationary-Phase Death

    Article • Archives of Biochemistry and Biophysics, September 1995, Elsevier

    Professor Ludmil T Benov

  74. Copper, Zinc Superoxide Dismutase in Escherichia coli: Periplasmic Localization

    Article • Archives of Biochemistry and Biophysics, June 1995, Elsevier

    Professor Ludmil T Benov

  75. Superoxide dismutase protects against aerobic heat shock in Escherichia coli.

    Article • Journal of Bacteriology, January 1995, ASM Journals

    Professor Ludmil T Benov

  76. The antioxidant activity of Flavonoids Isolated fromCorylus colurna

    Article • Phytotherapy Research, March 1994, Wiley

    Professor Ludmil T Benov

  77. A chemiluminescent investigation of the interaction of red cell membranes with thiol compounds

    Article • Journal of Electroanalytical Chemistry, February 1992, Elsevier

    Professor Ludmil T Benov

  78. A chemiluminescent investigation of the interaction of red cell membranes with thiol compounds

    Article • Bioelectrochemistry and Bioenergetics, February 1992, Elsevier

    Professor Ludmil T Benov

  79. A chemiluminescence method for determination of lipid hydroperoxides.

    Article • Journal of Clinical Biochemistry and Nutrition, January 1990, The Society for Free Radical Research Japan

    Professor Ludmil T Benov

  80. Thiol antidotes effect on lipid peroxidation in mercury-poisoned rats

    Article • Chemico-Biological Interactions, January 1990, Elsevier

    Professor Ludmil T Benov

  81. Initiation of lipid peroxidation in lysosomal membranes by activated blood polymorphonuclear leukocytes

    Article • Bulletin of Experimental Biology and Medicine, June 1988, Springer Science + Business Media

    Professor Ludmil T Benov

  82. HgCl2 increases the methemoglobin prooxidant activity. Possible mechanism of Hg2+-induced lipid peroxidation in erythrocytes

    Article • Chemico-Biological Interactions, June 1984, Elsevier

    Professor Ludmil T Benov

  83. Hemoglobin-catalyzed lipid peroxidation in the presence of mercuric chloride

    Article • Chemico-Biological Interactions, July 1983, Elsevier

    Professor Ludmil T Benov

  84. Possible contribution of oxyhemoglobin to the iron-induced hemolysis simultaneous effect of iron and hemoglobin on lipid peroxidation

    Article • Blut Zeitschrift für die gesamte Blutforschung, April 1983, Springer Science + Business Media

    Professor Ludmil T Benov

  85. Hemolysis and peroxidation in heavy metal-treated erythrocytes; GSH content and activities of some protecting enzymes

    Article • Cellular and Molecular Life Sciences, November 1982, Springer Science + Business Media

    Professor Ludmil T Benov

  86. The effect of lead on hemoglobin-catalyzed lipid peroxidation

    Article • Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, June 1981, Elsevier

    Professor Ludmil T Benov

  87. Relationship between the hemolytic action of heavy metals and lipid peroxidation

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, February 1981, Elsevier

    Professor Ludmil T Benov

  88. Short Chain Sugars as Endogenous Toxins

    Article • Wiley

    Professor Ludmil T Benov